Compile Data Set for Download or QSAR
Report error Found 41 Enz. Inhib. hit(s) with all data for entry = 6357
TargetHistone deacetylase 6(Human)
Karus Therapeutics

US Patent
LigandPNGBDBM124206(US8748458, 14)
Affinity DataIC50: 2nMT: 2°CAssay Description:In vitro HDAC assays were performed using a HDAC fluorescent activity assay kit (Biomol, UK) according to the manufacturer's instructions. Compounds ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2014
Entry Details
US Patent

TargetHistone deacetylase 6(Human)
Karus Therapeutics

US Patent
LigandPNGBDBM124207(US8748458, 15)
Affinity DataIC50: 3nMT: 2°CAssay Description:In vitro HDAC assays were performed using a HDAC fluorescent activity assay kit (Biomol, UK) according to the manufacturer's instructions. Compounds ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2014
Entry Details
US Patent

TargetHistone deacetylase 6(Human)
Karus Therapeutics

US Patent
LigandPNGBDBM124199(US8748458, 3)
Affinity DataIC50: 9nMT: 2°CAssay Description:In vitro HDAC assays were performed using a HDAC fluorescent activity assay kit (Biomol, UK) according to the manufacturer's instructions. Compounds ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2014
Entry Details
US Patent

TargetHistone deacetylase 6(Human)
Karus Therapeutics

US Patent
LigandPNGBDBM124205(US8748458, 11)
Affinity DataIC50: 13nMT: 2°CAssay Description:In vitro HDAC assays were performed using a HDAC fluorescent activity assay kit (Biomol, UK) according to the manufacturer's instructions. Compounds ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2014
Entry Details
US Patent

TargetHistone deacetylase 6(Human)
Karus Therapeutics

US Patent
LigandPNGBDBM124200(US8748458, 4)
Affinity DataIC50: 16nMT: 2°CAssay Description:In vitro HDAC assays were performed using a HDAC fluorescent activity assay kit (Biomol, UK) according to the manufacturer's instructions. Compounds ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2014
Entry Details
US Patent

TargetHistone deacetylase 6(Human)
Karus Therapeutics

US Patent
LigandPNGBDBM124202(US8748458, 8)
Affinity DataIC50: 19nMT: 2°CAssay Description:In vitro HDAC assays were performed using a HDAC fluorescent activity assay kit (Biomol, UK) according to the manufacturer's instructions. Compounds ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2014
Entry Details
US Patent

TargetHistone deacetylase 6(Human)
Karus Therapeutics

US Patent
LigandPNGBDBM124201(US8748458, 5)
Affinity DataIC50: 22nMT: 2°CAssay Description:In vitro HDAC assays were performed using a HDAC fluorescent activity assay kit (Biomol, UK) according to the manufacturer's instructions. Compounds ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2014
Entry Details
US Patent

TargetHistone deacetylase 6(Human)
Karus Therapeutics

US Patent
LigandPNGBDBM124203(US8748458, 9)
Affinity DataIC50: 31nMT: 2°CAssay Description:In vitro HDAC assays were performed using a HDAC fluorescent activity assay kit (Biomol, UK) according to the manufacturer's instructions. Compounds ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2014
Entry Details
US Patent

TargetHistone deacetylase 6(Human)
Karus Therapeutics

US Patent
LigandPNGBDBM124204(US8748458, 10)
Affinity DataIC50: 57nMT: 2°CAssay Description:In vitro HDAC assays were performed using a HDAC fluorescent activity assay kit (Biomol, UK) according to the manufacturer's instructions. Compounds ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2014
Entry Details
US Patent

TargetHistone deacetylase 3(Human)
Karus Therapeutics

US Patent
LigandPNGBDBM124200(US8748458, 4)
Affinity DataIC50: 62nMT: 2°CAssay Description:In vitro HDAC assays were performed using a HDAC fluorescent activity assay kit (Biomol, UK) according to the manufacturer's instructions. Compounds ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2014
Entry Details
US Patent

TargetHistone deacetylase 1(Human)
Karus Therapeutics

US Patent
LigandPNGBDBM124206(US8748458, 14)
Affinity DataIC50: 64nMT: 2°CAssay Description:In vitro HDAC assays were performed using a HDAC fluorescent activity assay kit (Biomol, UK) according to the manufacturer's instructions. Compounds ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2014
Entry Details
US Patent

TargetHistone deacetylase 6(Human)
Karus Therapeutics

US Patent
LigandPNGBDBM124198(US8748458, 1)
Affinity DataIC50: 68nMT: 2°CAssay Description:In vitro HDAC assays were performed using a HDAC fluorescent activity assay kit (Biomol, UK) according to the manufacturer's instructions. Compounds ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2014
Entry Details
US Patent

TargetHistone deacetylase 1(Human)
Karus Therapeutics

US Patent
LigandPNGBDBM124200(US8748458, 4)
Affinity DataIC50: 71nMT: 2°CAssay Description:In vitro HDAC assays were performed using a HDAC fluorescent activity assay kit (Biomol, UK) according to the manufacturer's instructions. Compounds ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2014
Entry Details
US Patent

TargetHistone deacetylase 9(Human)
Karus Therapeutics

US Patent
LigandPNGBDBM124200(US8748458, 4)
Affinity DataIC50: 90nMT: 2°CAssay Description:In vitro HDAC assays were performed using a HDAC fluorescent activity assay kit (Biomol, UK) according to the manufacturer's instructions. Compounds ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2014
Entry Details
US Patent

TargetHistone deacetylase 11(Human)
Karus Therapeutics

US Patent
LigandPNGBDBM124200(US8748458, 4)
Affinity DataIC50: 112nMT: 2°CAssay Description:In vitro HDAC assays were performed using a HDAC fluorescent activity assay kit (Biomol, UK) according to the manufacturer's instructions. Compounds ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2014
Entry Details
US Patent

TargetHistone deacetylase 1(Human)
Karus Therapeutics

US Patent
LigandPNGBDBM124202(US8748458, 8)
Affinity DataIC50: 116nMT: 2°CAssay Description:In vitro HDAC assays were performed using a HDAC fluorescent activity assay kit (Biomol, UK) according to the manufacturer's instructions. Compounds ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2014
Entry Details
US Patent

TargetHistone deacetylase 5(Human)
Karus Therapeutics

US Patent
LigandPNGBDBM124200(US8748458, 4)
Affinity DataIC50: 123nMT: 2°CAssay Description:In vitro HDAC assays were performed using a HDAC fluorescent activity assay kit (Biomol, UK) according to the manufacturer's instructions. Compounds ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2014
Entry Details
US Patent

TargetPolyamine deacetylase HDAC10(Human)
Karus Therapeutics

US Patent
LigandPNGBDBM124200(US8748458, 4)
Affinity DataIC50: 126nMT: 2°CAssay Description:In vitro HDAC assays were performed using a HDAC fluorescent activity assay kit (Biomol, UK) according to the manufacturer's instructions. Compounds ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2014
Entry Details
US Patent

TargetHistone deacetylase 9(Human)
Karus Therapeutics

US Patent
LigandPNGBDBM124206(US8748458, 14)
Affinity DataIC50: 145nMT: 2°CAssay Description:In vitro HDAC assays were performed using a HDAC fluorescent activity assay kit (Biomol, UK) according to the manufacturer's instructions. Compounds ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2014
Entry Details
US Patent

TargetHistone deacetylase 1(Human)
Karus Therapeutics

US Patent
LigandPNGBDBM124207(US8748458, 15)
Affinity DataIC50: 151nMT: 2°CAssay Description:In vitro HDAC assays were performed using a HDAC fluorescent activity assay kit (Biomol, UK) according to the manufacturer's instructions. Compounds ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2014
Entry Details
US Patent

TargetHistone deacetylase 7(Human)
Karus Therapeutics

US Patent
LigandPNGBDBM124200(US8748458, 4)
Affinity DataIC50: 157nMT: 2°CAssay Description:In vitro HDAC assays were performed using a HDAC fluorescent activity assay kit (Biomol, UK) according to the manufacturer's instructions. Compounds ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2014
Entry Details
US Patent

TargetHistone deacetylase 1(Human)
Karus Therapeutics

US Patent
LigandPNGBDBM124198(US8748458, 1)
Affinity DataIC50: 158nMT: 2°CAssay Description:In vitro HDAC assays were performed using a HDAC fluorescent activity assay kit (Biomol, UK) according to the manufacturer's instructions. Compounds ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2014
Entry Details
US Patent

TargetHistone deacetylase 1(Human)
Karus Therapeutics

US Patent
LigandPNGBDBM124205(US8748458, 11)
Affinity DataIC50: 182nMT: 2°CAssay Description:In vitro HDAC assays were performed using a HDAC fluorescent activity assay kit (Biomol, UK) according to the manufacturer's instructions. Compounds ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2014
Entry Details
US Patent

TargetHistone deacetylase 1(Human)
Karus Therapeutics

US Patent
LigandPNGBDBM124204(US8748458, 10)
Affinity DataIC50: 182nMT: 2°CAssay Description:In vitro HDAC assays were performed using a HDAC fluorescent activity assay kit (Biomol, UK) according to the manufacturer's instructions. Compounds ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2014
Entry Details
US Patent

TargetHistone deacetylase 2(Human)
Karus Therapeutics

US Patent
LigandPNGBDBM124200(US8748458, 4)
Affinity DataIC50: 212nMT: 2°CAssay Description:In vitro HDAC assays were performed using a HDAC fluorescent activity assay kit (Biomol, UK) according to the manufacturer's instructions. Compounds ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2014
Entry Details
US Patent

TargetHistone deacetylase 2(Human)
Karus Therapeutics

US Patent
LigandPNGBDBM124206(US8748458, 14)
Affinity DataIC50: 306nMT: 2°CAssay Description:In vitro HDAC assays were performed using a HDAC fluorescent activity assay kit (Biomol, UK) according to the manufacturer's instructions. Compounds ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2014
Entry Details
US Patent

TargetHistone deacetylase 4(Human)
Karus Therapeutics

US Patent
LigandPNGBDBM124199(US8748458, 3)
Affinity DataIC50: 307nMT: 2°CAssay Description:In vitro HDAC assays were performed using a HDAC fluorescent activity assay kit (Biomol, UK) according to the manufacturer's instructions. Compounds ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2014
Entry Details
US Patent

TargetHistone deacetylase 8(Human)
Karus Therapeutics

US Patent
LigandPNGBDBM124200(US8748458, 4)
Affinity DataIC50: 312nMT: 2°CAssay Description:In vitro HDAC assays were performed using a HDAC fluorescent activity assay kit (Biomol, UK) according to the manufacturer's instructions. Compounds ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2014
Entry Details
US Patent

TargetHistone deacetylase 9(Human)
Karus Therapeutics

US Patent
LigandPNGBDBM124207(US8748458, 15)
Affinity DataIC50: 423nMT: 2°CAssay Description:In vitro HDAC assays were performed using a HDAC fluorescent activity assay kit (Biomol, UK) according to the manufacturer's instructions. Compounds ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2014
Entry Details
US Patent

TargetHistone deacetylase 1(Human)
Karus Therapeutics

US Patent
LigandPNGBDBM124203(US8748458, 9)
Affinity DataIC50: 453nMT: 2°CAssay Description:In vitro HDAC assays were performed using a HDAC fluorescent activity assay kit (Biomol, UK) according to the manufacturer's instructions. Compounds ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2014
Entry Details
US Patent

TargetHistone deacetylase 5(Human)
Karus Therapeutics

US Patent
LigandPNGBDBM124199(US8748458, 3)
Affinity DataIC50: 458nMT: 2°CAssay Description:In vitro HDAC assays were performed using a HDAC fluorescent activity assay kit (Biomol, UK) according to the manufacturer's instructions. Compounds ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2014
Entry Details
US Patent

TargetHistone deacetylase 1(Human)
Karus Therapeutics

US Patent
LigandPNGBDBM124199(US8748458, 3)
Affinity DataIC50: 458nMT: 2°CAssay Description:In vitro HDAC assays were performed using a HDAC fluorescent activity assay kit (Biomol, UK) according to the manufacturer's instructions. Compounds ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2014
Entry Details
US Patent

TargetHistone deacetylase 4(Human)
Karus Therapeutics

US Patent
LigandPNGBDBM124200(US8748458, 4)
Affinity DataIC50: 545nMT: 2°CAssay Description:In vitro HDAC assays were performed using a HDAC fluorescent activity assay kit (Biomol, UK) according to the manufacturer's instructions. Compounds ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2014
Entry Details
US Patent

TargetHistone deacetylase 2(Human)
Karus Therapeutics

US Patent
LigandPNGBDBM124207(US8748458, 15)
Affinity DataIC50: 612nMT: 2°CAssay Description:In vitro HDAC assays were performed using a HDAC fluorescent activity assay kit (Biomol, UK) according to the manufacturer's instructions. Compounds ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2014
Entry Details
US Patent

TargetHistone deacetylase 1(Human)
Karus Therapeutics

US Patent
LigandPNGBDBM124201(US8748458, 5)
Affinity DataIC50: 642nMT: 2°CAssay Description:In vitro HDAC assays were performed using a HDAC fluorescent activity assay kit (Biomol, UK) according to the manufacturer's instructions. Compounds ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2014
Entry Details
US Patent

TargetHistone deacetylase 3(Human)
Karus Therapeutics

US Patent
LigandPNGBDBM124199(US8748458, 3)
Affinity DataIC50: 710nMT: 2°CAssay Description:In vitro HDAC assays were performed using a HDAC fluorescent activity assay kit (Biomol, UK) according to the manufacturer's instructions. Compounds ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2014
Entry Details
US Patent

TargetHistone deacetylase 9(Human)
Karus Therapeutics

US Patent
LigandPNGBDBM124203(US8748458, 9)
Affinity DataIC50: 759nMT: 2°CAssay Description:In vitro HDAC assays were performed using a HDAC fluorescent activity assay kit (Biomol, UK) according to the manufacturer's instructions. Compounds ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2014
Entry Details
US Patent

TargetHistone deacetylase 9(Human)
Karus Therapeutics

US Patent
LigandPNGBDBM124205(US8748458, 11)
Affinity DataIC50: 759nMT: 2°CAssay Description:In vitro HDAC assays were performed using a HDAC fluorescent activity assay kit (Biomol, UK) according to the manufacturer's instructions. Compounds ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2014
Entry Details
US Patent

TargetHistone deacetylase 2(Human)
Karus Therapeutics

US Patent
LigandPNGBDBM124205(US8748458, 11)
Affinity DataIC50: 883nMT: 2°CAssay Description:In vitro HDAC assays were performed using a HDAC fluorescent activity assay kit (Biomol, UK) according to the manufacturer's instructions. Compounds ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2014
Entry Details
US Patent

TargetHistone deacetylase 2(Human)
Karus Therapeutics

US Patent
LigandPNGBDBM124203(US8748458, 9)
Affinity DataIC50: 1.14E+3nMT: 2°CAssay Description:In vitro HDAC assays were performed using a HDAC fluorescent activity assay kit (Biomol, UK) according to the manufacturer's instructions. Compounds ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2014
Entry Details
US Patent

TargetHistone deacetylase 2(Human)
Karus Therapeutics

US Patent
LigandPNGBDBM124199(US8748458, 3)
Affinity DataIC50: 1.54E+3nMT: 2°CAssay Description:In vitro HDAC assays were performed using a HDAC fluorescent activity assay kit (Biomol, UK) according to the manufacturer's instructions. Compounds ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2014
Entry Details
US Patent