Compile Data Set for Download or QSAR
Report error Found 9 Enz. Inhib. hit(s) with all data for entry = 6351
TargetGenome polyprotein(Hepacivirus C)
Janssen Ireland

US Patent
LigandChemical structure of BindingDB Monomer ID 123410BDBM123410(US8754106, 82 | US8754106, 91 | US8741926, 82)
Affinity DataKi:  0.0500nMAssay Description:The aim of this in vitro assay was to measure the inhibition of HCV NS3/4A protease complexes by the compounds of the present invention. This assay p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2014
Entry Details
US Patent

TargetGenome polyprotein(Hepacivirus C)
Janssen Ireland

US Patent
LigandChemical structure of BindingDB Monomer ID 123413BDBM123413(US8754106, 94 | US8741926, 94)
Affinity DataKi:  0.100nMAssay Description:The aim of this in vitro assay was to measure the inhibition of HCV NS3/4A protease complexes by the compounds of the present invention. This assay p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2014
Entry Details
US Patent

TargetGenome polyprotein(Hepacivirus C)
Janssen Ireland

US Patent
LigandChemical structure of BindingDB Monomer ID 124106BDBM124106(US8754106, 56)
Affinity DataKi:  0.100nMAssay Description:The aim of this in vitro assay was to measure the inhibition of HCV NS3/4A protease complexes by the compounds of the present invention. This assay p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2014
Entry Details
US Patent

TargetGenome polyprotein(Hepacivirus C)
Janssen Ireland

US Patent
LigandChemical structure of BindingDB Monomer ID 123415BDBM123415(US8754106, 95 | US8741926, 95)
Affinity DataKi:  0.100nMAssay Description:The aim of this in vitro assay was to measure the inhibition of HCV NS3/4A protease complexes by the compounds of the present invention. This assay p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2014
Entry Details
US Patent

TargetGenome polyprotein(Hepacivirus C)
Janssen Ireland

US Patent
LigandChemical structure of BindingDB Monomer ID 123414BDBM123414(US8754106, 48 | US8741926, 48)
Affinity DataKi:  0.25nMAssay Description:The aim of this in vitro assay was to measure the inhibition of HCV NS3/4A protease complexes by the compounds of the present invention. This assay p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2014
Entry Details
US Patent

TargetGenome polyprotein(Hepacivirus C)
Janssen Ireland

US Patent
LigandChemical structure of BindingDB Monomer ID 123412BDBM123412(US8754106, 57 | US8741926, 57)
Affinity DataKi:  0.300nMAssay Description:The aim of this in vitro assay was to measure the inhibition of HCV NS3/4A protease complexes by the compounds of the present invention. This assay p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2014
Entry Details
US Patent

TargetGenome polyprotein(Hepacivirus C)
Janssen Ireland

US Patent
LigandChemical structure of BindingDB Monomer ID 50336504BDBM50336504((2R,3aR,11aS,12aR,14aR)-N-(cyclopropylsulfonyl)-2-...)
Affinity DataKi:  0.5nMAssay Description:The aim of this in vitro assay was to measure the inhibition of HCV NS3/4A protease complexes by the compounds of the present invention. This assay p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2014
Entry Details
US Patent

TargetGenome polyprotein(Hepacivirus C)
Janssen Ireland

US Patent
LigandChemical structure of BindingDB Monomer ID 124105BDBM124105(US8754106, 55)
Affinity DataKi:  5nMAssay Description:The aim of this in vitro assay was to measure the inhibition of HCV NS3/4A protease complexes by the compounds of the present invention. This assay p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2014
Entry Details
US Patent

TargetGenome polyprotein(Hepacivirus C)
Janssen Ireland

US Patent
LigandChemical structure of BindingDB Monomer ID 123410BDBM123410(US8754106, 82 | US8754106, 91 | US8741926, 82)
Affinity DataKi:  9.40nMAssay Description:The aim of this in vitro assay was to measure the inhibition of HCV NS3/4A protease complexes by the compounds of the present invention. This assay p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2014
Entry Details
US Patent