Compile Data Set for Download or QSAR
Report error Found 30 Enz. Inhib. hit(s) with all data for entry = 6426
TargetMetabotropic glutamate receptor 5(Rat)
Vanderbilt University

US Patent
LigandChemical structure of BindingDB Monomer ID 128279BDBM128279(US8796295, Table 2: Compound: 3)
Affinity DataIC50: 6.90nMAssay Description:The utility of the compounds in accordance with the present invention as negative allosteric modulators of metabotropic glutamate receptor activity, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/12/2015
Entry Details
US Patent

TargetMetabotropic glutamate receptor 5(Human)
Vanderbilt University

US Patent
LigandChemical structure of BindingDB Monomer ID 128283BDBM128283(US8796295, Table 2: Compound: 7)
Affinity DataIC50: 8.10nMAssay Description:The utility of the compounds in accordance with the present invention as negative allosteric modulators of metabotropic glutamate receptor activity, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/12/2015
Entry Details
US Patent

TargetMetabotropic glutamate receptor 5(Human)
Vanderbilt University

US Patent
LigandChemical structure of BindingDB Monomer ID 128279BDBM128279(US8796295, Table 2: Compound: 3)
Affinity DataIC50: 9.30nMAssay Description:The utility of the compounds in accordance with the present invention as negative allosteric modulators of metabotropic glutamate receptor activity, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/12/2015
Entry Details
US Patent

TargetMetabotropic glutamate receptor 5(Human)
Vanderbilt University

US Patent
LigandChemical structure of BindingDB Monomer ID 128281BDBM128281(US8796295, Table 2: Compound: 5)
Affinity DataIC50: 11nMAssay Description:The utility of the compounds in accordance with the present invention as negative allosteric modulators of metabotropic glutamate receptor activity, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/12/2015
Entry Details
US Patent

TargetMetabotropic glutamate receptor 5(Human)
Vanderbilt University

US Patent
LigandChemical structure of BindingDB Monomer ID 128282BDBM128282(US8796295, Table 2: Compound: 6)
Affinity DataIC50: 15nMAssay Description:The utility of the compounds in accordance with the present invention as negative allosteric modulators of metabotropic glutamate receptor activity, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/12/2015
Entry Details
US Patent

TargetMetabotropic glutamate receptor 5(Rat)
Vanderbilt University

US Patent
LigandChemical structure of BindingDB Monomer ID 128281BDBM128281(US8796295, Table 2: Compound: 5)
Affinity DataIC50: 16nMAssay Description:The utility of the compounds in accordance with the present invention as negative allosteric modulators of metabotropic glutamate receptor activity, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/12/2015
Entry Details
US Patent

TargetMetabotropic glutamate receptor 5(Rat)
Vanderbilt University

US Patent
LigandChemical structure of BindingDB Monomer ID 128283BDBM128283(US8796295, Table 2: Compound: 7)
Affinity DataIC50: 17nMAssay Description:The utility of the compounds in accordance with the present invention as negative allosteric modulators of metabotropic glutamate receptor activity, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/12/2015
Entry Details
US Patent

TargetMetabotropic glutamate receptor 5(Human)
Vanderbilt University

US Patent
LigandChemical structure of BindingDB Monomer ID 128280BDBM128280(US8796295, Table 2: Compound: 4)
Affinity DataIC50: 19nMAssay Description:The utility of the compounds in accordance with the present invention as negative allosteric modulators of metabotropic glutamate receptor activity, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/12/2015
Entry Details
US Patent

TargetMetabotropic glutamate receptor 5(Rat)
Vanderbilt University

US Patent
LigandChemical structure of BindingDB Monomer ID 128286BDBM128286(US8796295, Table 2: Compound: 10)
Affinity DataIC50: 20nMAssay Description:The utility of the compounds in accordance with the present invention as negative allosteric modulators of metabotropic glutamate receptor activity, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/12/2015
Entry Details
US Patent

TargetMetabotropic glutamate receptor 5(Rat)
Vanderbilt University

US Patent
LigandChemical structure of BindingDB Monomer ID 128285BDBM128285(US8796295, Table 2: Compound: 9)
Affinity DataIC50: 21nMAssay Description:The utility of the compounds in accordance with the present invention as negative allosteric modulators of metabotropic glutamate receptor activity, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/12/2015
Entry Details
US Patent

TargetMetabotropic glutamate receptor 5(Rat)
Vanderbilt University

US Patent
LigandChemical structure of BindingDB Monomer ID 128280BDBM128280(US8796295, Table 2: Compound: 4)
Affinity DataIC50: 21nMAssay Description:The utility of the compounds in accordance with the present invention as negative allosteric modulators of metabotropic glutamate receptor activity, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/12/2015
Entry Details
US Patent

TargetMetabotropic glutamate receptor 5(Human)
Vanderbilt University

US Patent
LigandChemical structure of BindingDB Monomer ID 50442525BDBM50442525(CHEMBL2440659 | US8796295, Table 2: Compound: 1)
Affinity DataIC50: 23nMAssay Description:The utility of the compounds in accordance with the present invention as negative allosteric modulators of metabotropic glutamate receptor activity, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/12/2015
Entry Details
US Patent

TargetMetabotropic glutamate receptor 5(Rat)
Vanderbilt University

US Patent
LigandChemical structure of BindingDB Monomer ID 50442525BDBM50442525(CHEMBL2440659 | US8796295, Table 2: Compound: 1)
Affinity DataIC50: 25nMAssay Description:The utility of the compounds in accordance with the present invention as negative allosteric modulators of metabotropic glutamate receptor activity, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/12/2015
Entry Details
US Patent

TargetMetabotropic glutamate receptor 5(Rat)
Vanderbilt University

US Patent
LigandChemical structure of BindingDB Monomer ID 128282BDBM128282(US8796295, Table 2: Compound: 6)
Affinity DataIC50: 31nMAssay Description:The utility of the compounds in accordance with the present invention as negative allosteric modulators of metabotropic glutamate receptor activity, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/12/2015
Entry Details
US Patent

TargetMetabotropic glutamate receptor 5(Rat)
Vanderbilt University

US Patent
LigandChemical structure of BindingDB Monomer ID 128278BDBM128278(US8796295, Table 2: Compound: 2)
Affinity DataIC50: 44nMAssay Description:The utility of the compounds in accordance with the present invention as negative allosteric modulators of metabotropic glutamate receptor activity, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/12/2015
Entry Details
US Patent

TargetMetabotropic glutamate receptor 5(Human)
Vanderbilt University

US Patent
LigandChemical structure of BindingDB Monomer ID 128284BDBM128284(US8796295, Table 2: Compound: 8)
Affinity DataIC50: 51nMAssay Description:The utility of the compounds in accordance with the present invention as negative allosteric modulators of metabotropic glutamate receptor activity, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/12/2015
Entry Details
US Patent

TargetMetabotropic glutamate receptor 5(Rat)
Vanderbilt University

US Patent
LigandChemical structure of BindingDB Monomer ID 128284BDBM128284(US8796295, Table 2: Compound: 8)
Affinity DataIC50: 65nMAssay Description:The utility of the compounds in accordance with the present invention as negative allosteric modulators of metabotropic glutamate receptor activity, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/12/2015
Entry Details
US Patent

TargetMetabotropic glutamate receptor 5(Human)
Vanderbilt University

US Patent
LigandChemical structure of BindingDB Monomer ID 128285BDBM128285(US8796295, Table 2: Compound: 9)
Affinity DataIC50: 78nMAssay Description:The utility of the compounds in accordance with the present invention as negative allosteric modulators of metabotropic glutamate receptor activity, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/12/2015
Entry Details
US Patent

TargetMetabotropic glutamate receptor 5(Human)
Vanderbilt University

US Patent
LigandChemical structure of BindingDB Monomer ID 128278BDBM128278(US8796295, Table 2: Compound: 2)
Affinity DataIC50: 129nMAssay Description:The utility of the compounds in accordance with the present invention as negative allosteric modulators of metabotropic glutamate receptor activity, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/12/2015
Entry Details
US Patent

TargetMetabotropic glutamate receptor 5(Human)
Vanderbilt University

US Patent
LigandChemical structure of BindingDB Monomer ID 128286BDBM128286(US8796295, Table 2: Compound: 10)
Affinity DataIC50: 296nMAssay Description:The utility of the compounds in accordance with the present invention as negative allosteric modulators of metabotropic glutamate receptor activity, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/12/2015
Entry Details
US Patent

TargetMetabotropic glutamate receptor 5(Rat)
Vanderbilt University

US Patent
LigandChemical structure of BindingDB Monomer ID 128287BDBM128287(US8796295, Table 2: Compound: 11)
Affinity DataIC50: 407nMAssay Description:The utility of the compounds in accordance with the present invention as negative allosteric modulators of metabotropic glutamate receptor activity, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/12/2015
Entry Details
US Patent

TargetMetabotropic glutamate receptor 5(Human)
Vanderbilt University

US Patent
LigandChemical structure of BindingDB Monomer ID 128287BDBM128287(US8796295, Table 2: Compound: 11)
Affinity DataIC50: 477nMAssay Description:The utility of the compounds in accordance with the present invention as negative allosteric modulators of metabotropic glutamate receptor activity, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/12/2015
Entry Details
US Patent

TargetMetabotropic glutamate receptor 5(Rat)
Vanderbilt University

US Patent
LigandChemical structure of BindingDB Monomer ID 128288BDBM128288(US8796295, Table 2: Compound: 12)
Affinity DataIC50: 813nMAssay Description:The utility of the compounds in accordance with the present invention as negative allosteric modulators of metabotropic glutamate receptor activity, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/12/2015
Entry Details
US Patent

TargetMetabotropic glutamate receptor 5(Human)
Vanderbilt University

US Patent
LigandChemical structure of BindingDB Monomer ID 128288BDBM128288(US8796295, Table 2: Compound: 12)
Affinity DataIC50: 1.07E+3nMAssay Description:The utility of the compounds in accordance with the present invention as negative allosteric modulators of metabotropic glutamate receptor activity, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/12/2015
Entry Details
US Patent

TargetMetabotropic glutamate receptor 5(Rat)
Vanderbilt University

US Patent
LigandChemical structure of BindingDB Monomer ID 128290BDBM128290(US8796295, Table 2: Compound: 14)
Affinity DataIC50: 2.52E+3nMAssay Description:The utility of the compounds in accordance with the present invention as negative allosteric modulators of metabotropic glutamate receptor activity, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/12/2015
Entry Details
US Patent

TargetMetabotropic glutamate receptor 5(Human)
Vanderbilt University

US Patent
LigandChemical structure of BindingDB Monomer ID 128290BDBM128290(US8796295, Table 2: Compound: 14)
Affinity DataIC50: 3.14E+3nMAssay Description:The utility of the compounds in accordance with the present invention as negative allosteric modulators of metabotropic glutamate receptor activity, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/12/2015
Entry Details
US Patent

TargetMetabotropic glutamate receptor 5(Rat)
Vanderbilt University

US Patent
LigandChemical structure of BindingDB Monomer ID 128289BDBM128289(US8796295, Table 2: Compound: 13)
Affinity DataIC50: 4.04E+3nMAssay Description:The utility of the compounds in accordance with the present invention as negative allosteric modulators of metabotropic glutamate receptor activity, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/12/2015
Entry Details
US Patent

TargetMetabotropic glutamate receptor 5(Human)
Vanderbilt University

US Patent
LigandChemical structure of BindingDB Monomer ID 128289BDBM128289(US8796295, Table 2: Compound: 13)
Affinity DataIC50: 5.12E+3nMAssay Description:The utility of the compounds in accordance with the present invention as negative allosteric modulators of metabotropic glutamate receptor activity, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/12/2015
Entry Details
US Patent

TargetMetabotropic glutamate receptor 5(Rat)
Vanderbilt University

US Patent
LigandChemical structure of BindingDB Monomer ID 128291BDBM128291(US8796295, Table 2: Compound: 15)
Affinity DataIC50: 3.00E+4nMAssay Description:The utility of the compounds in accordance with the present invention as negative allosteric modulators of metabotropic glutamate receptor activity, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/12/2015
Entry Details
US Patent

TargetMetabotropic glutamate receptor 5(Human)
Vanderbilt University

US Patent
LigandChemical structure of BindingDB Monomer ID 128291BDBM128291(US8796295, Table 2: Compound: 15)
Affinity DataIC50: 3.00E+4nMAssay Description:The utility of the compounds in accordance with the present invention as negative allosteric modulators of metabotropic glutamate receptor activity, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/12/2015
Entry Details
US Patent