Compile Data Set for Download or QSAR
maximum 50k data
Found 30 Enz. Inhib. hit(s) with all data for entry = 6426
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Vanderbilt University

US Patent
LigandPNGBDBM128279(US8796295, Table 2: Compound: 3)
Affinity DataIC50:  6.90nMAssay Description:The utility of the compounds in accordance with the present invention as negative allosteric modulators of metabotropic glutamate receptor activity, ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Vanderbilt University

US Patent
LigandPNGBDBM128283(US8796295, Table 2: Compound: 7)
Affinity DataIC50:  8.10nMAssay Description:The utility of the compounds in accordance with the present invention as negative allosteric modulators of metabotropic glutamate receptor activity, ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Vanderbilt University

US Patent
LigandPNGBDBM128279(US8796295, Table 2: Compound: 3)
Affinity DataIC50:  9.30nMAssay Description:The utility of the compounds in accordance with the present invention as negative allosteric modulators of metabotropic glutamate receptor activity, ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Vanderbilt University

US Patent
LigandPNGBDBM128281(US8796295, Table 2: Compound: 5)
Affinity DataIC50:  11nMAssay Description:The utility of the compounds in accordance with the present invention as negative allosteric modulators of metabotropic glutamate receptor activity, ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Vanderbilt University

US Patent
LigandPNGBDBM128282(US8796295, Table 2: Compound: 6)
Affinity DataIC50:  15nMAssay Description:The utility of the compounds in accordance with the present invention as negative allosteric modulators of metabotropic glutamate receptor activity, ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Vanderbilt University

US Patent
LigandPNGBDBM128281(US8796295, Table 2: Compound: 5)
Affinity DataIC50:  16nMAssay Description:The utility of the compounds in accordance with the present invention as negative allosteric modulators of metabotropic glutamate receptor activity, ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Vanderbilt University

US Patent
LigandPNGBDBM128283(US8796295, Table 2: Compound: 7)
Affinity DataIC50:  17nMAssay Description:The utility of the compounds in accordance with the present invention as negative allosteric modulators of metabotropic glutamate receptor activity, ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Vanderbilt University

US Patent
LigandPNGBDBM128280(US8796295, Table 2: Compound: 4)
Affinity DataIC50:  19nMAssay Description:The utility of the compounds in accordance with the present invention as negative allosteric modulators of metabotropic glutamate receptor activity, ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Vanderbilt University

US Patent
LigandPNGBDBM128286(US8796295, Table 2: Compound: 10)
Affinity DataIC50:  20nMAssay Description:The utility of the compounds in accordance with the present invention as negative allosteric modulators of metabotropic glutamate receptor activity, ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Vanderbilt University

US Patent
LigandPNGBDBM128285(US8796295, Table 2: Compound: 9)
Affinity DataIC50:  21nMAssay Description:The utility of the compounds in accordance with the present invention as negative allosteric modulators of metabotropic glutamate receptor activity, ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Vanderbilt University

US Patent
LigandPNGBDBM128280(US8796295, Table 2: Compound: 4)
Affinity DataIC50:  21nMAssay Description:The utility of the compounds in accordance with the present invention as negative allosteric modulators of metabotropic glutamate receptor activity, ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Vanderbilt University

US Patent
LigandPNGBDBM50442525(CHEMBL2440659 | US8796295, Table 2: Compound: 1)
Affinity DataIC50:  23nMAssay Description:The utility of the compounds in accordance with the present invention as negative allosteric modulators of metabotropic glutamate receptor activity, ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Vanderbilt University

US Patent
LigandPNGBDBM50442525(CHEMBL2440659 | US8796295, Table 2: Compound: 1)
Affinity DataIC50:  25nMAssay Description:The utility of the compounds in accordance with the present invention as negative allosteric modulators of metabotropic glutamate receptor activity, ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Vanderbilt University

US Patent
LigandPNGBDBM128282(US8796295, Table 2: Compound: 6)
Affinity DataIC50:  31nMAssay Description:The utility of the compounds in accordance with the present invention as negative allosteric modulators of metabotropic glutamate receptor activity, ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Vanderbilt University

US Patent
LigandPNGBDBM128278(US8796295, Table 2: Compound: 2)
Affinity DataIC50:  44nMAssay Description:The utility of the compounds in accordance with the present invention as negative allosteric modulators of metabotropic glutamate receptor activity, ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Vanderbilt University

US Patent
LigandPNGBDBM128284(US8796295, Table 2: Compound: 8)
Affinity DataIC50:  51nMAssay Description:The utility of the compounds in accordance with the present invention as negative allosteric modulators of metabotropic glutamate receptor activity, ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Vanderbilt University

US Patent
LigandPNGBDBM128284(US8796295, Table 2: Compound: 8)
Affinity DataIC50:  65nMAssay Description:The utility of the compounds in accordance with the present invention as negative allosteric modulators of metabotropic glutamate receptor activity, ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Vanderbilt University

US Patent
LigandPNGBDBM128285(US8796295, Table 2: Compound: 9)
Affinity DataIC50:  78nMAssay Description:The utility of the compounds in accordance with the present invention as negative allosteric modulators of metabotropic glutamate receptor activity, ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Vanderbilt University

US Patent
LigandPNGBDBM128278(US8796295, Table 2: Compound: 2)
Affinity DataIC50:  129nMAssay Description:The utility of the compounds in accordance with the present invention as negative allosteric modulators of metabotropic glutamate receptor activity, ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Vanderbilt University

US Patent
LigandPNGBDBM128286(US8796295, Table 2: Compound: 10)
Affinity DataIC50:  296nMAssay Description:The utility of the compounds in accordance with the present invention as negative allosteric modulators of metabotropic glutamate receptor activity, ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Vanderbilt University

US Patent
LigandPNGBDBM128287(US8796295, Table 2: Compound: 11)
Affinity DataIC50:  407nMAssay Description:The utility of the compounds in accordance with the present invention as negative allosteric modulators of metabotropic glutamate receptor activity, ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Vanderbilt University

US Patent
LigandPNGBDBM128287(US8796295, Table 2: Compound: 11)
Affinity DataIC50:  477nMAssay Description:The utility of the compounds in accordance with the present invention as negative allosteric modulators of metabotropic glutamate receptor activity, ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Vanderbilt University

US Patent
LigandPNGBDBM128288(US8796295, Table 2: Compound: 12)
Affinity DataIC50:  813nMAssay Description:The utility of the compounds in accordance with the present invention as negative allosteric modulators of metabotropic glutamate receptor activity, ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Vanderbilt University

US Patent
LigandPNGBDBM128288(US8796295, Table 2: Compound: 12)
Affinity DataIC50:  1.07E+3nMAssay Description:The utility of the compounds in accordance with the present invention as negative allosteric modulators of metabotropic glutamate receptor activity, ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Vanderbilt University

US Patent
LigandPNGBDBM128290(US8796295, Table 2: Compound: 14)
Affinity DataIC50:  2.52E+3nMAssay Description:The utility of the compounds in accordance with the present invention as negative allosteric modulators of metabotropic glutamate receptor activity, ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Vanderbilt University

US Patent
LigandPNGBDBM128290(US8796295, Table 2: Compound: 14)
Affinity DataIC50:  3.14E+3nMAssay Description:The utility of the compounds in accordance with the present invention as negative allosteric modulators of metabotropic glutamate receptor activity, ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Vanderbilt University

US Patent
LigandPNGBDBM128289(US8796295, Table 2: Compound: 13)
Affinity DataIC50:  4.04E+3nMAssay Description:The utility of the compounds in accordance with the present invention as negative allosteric modulators of metabotropic glutamate receptor activity, ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Vanderbilt University

US Patent
LigandPNGBDBM128289(US8796295, Table 2: Compound: 13)
Affinity DataIC50:  5.12E+3nMAssay Description:The utility of the compounds in accordance with the present invention as negative allosteric modulators of metabotropic glutamate receptor activity, ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Vanderbilt University

US Patent
LigandPNGBDBM128291(US8796295, Table 2: Compound: 15)
Affinity DataIC50: >3.00E+4nMAssay Description:The utility of the compounds in accordance with the present invention as negative allosteric modulators of metabotropic glutamate receptor activity, ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Vanderbilt University

US Patent
LigandPNGBDBM128291(US8796295, Table 2: Compound: 15)
Affinity DataIC50: >3.00E+4nMAssay Description:The utility of the compounds in accordance with the present invention as negative allosteric modulators of metabotropic glutamate receptor activity, ...More data for this Ligand-Target Pair
In DepthDetails US Patent