Compile Data Set for Download or QSAR
Report error Found 25 Enz. Inhib. hit(s) with all data for entry = 6481
TargetSphingosine 1-phosphate receptor 1(Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 131715BDBM131715(US8835470, 74)
Affinity DataIC50: 0.300nMpH: 7.5Assay Description:Membranes were prepared from CHO cells expressing human S1P1. Cells were dissociated in buffer containing 20 mM HEPES, pH 7.5, 50 mM NaCl, 2 mM EDTA ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/16/2015
Entry Details
US Patent

TargetSphingosine 1-phosphate receptor 1(Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 131700BDBM131700(US8835470, 6)
Affinity DataIC50: 0.460nMpH: 7.5Assay Description:Membranes were prepared from CHO cells expressing human S1P1. Cells were dissociated in buffer containing 20 mM HEPES, pH 7.5, 50 mM NaCl, 2 mM EDTA ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/16/2015
Entry Details
US Patent

TargetSphingosine 1-phosphate receptor 1(Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 131714BDBM131714(US8835470, 71)
Affinity DataIC50: 0.850nMpH: 7.5Assay Description:Membranes were prepared from CHO cells expressing human S1P1. Cells were dissociated in buffer containing 20 mM HEPES, pH 7.5, 50 mM NaCl, 2 mM EDTA ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/16/2015
Entry Details
US Patent

TargetSphingosine 1-phosphate receptor 1(Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 131701BDBM131701(US8835470, 10)
Affinity DataIC50: 2nMpH: 7.5Assay Description:Membranes were prepared from CHO cells expressing human S1P1. Cells were dissociated in buffer containing 20 mM HEPES, pH 7.5, 50 mM NaCl, 2 mM EDTA ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/16/2015
Entry Details
US Patent

TargetSphingosine 1-phosphate receptor 1(Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 131721BDBM131721(US8835470, 126)
Affinity DataIC50: 2.10nMpH: 7.5Assay Description:Membranes were prepared from CHO cells expressing human S1P1. Cells were dissociated in buffer containing 20 mM HEPES, pH 7.5, 50 mM NaCl, 2 mM EDTA ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/16/2015
Entry Details
US Patent

TargetSphingosine 1-phosphate receptor 1(Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 131709BDBM131709(US8835470, 41)
Affinity DataIC50: 2.60nMpH: 7.5Assay Description:Membranes were prepared from CHO cells expressing human S1P1. Cells were dissociated in buffer containing 20 mM HEPES, pH 7.5, 50 mM NaCl, 2 mM EDTA ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/16/2015
Entry Details
US Patent

TargetSphingosine 1-phosphate receptor 1(Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 131708BDBM131708(US8835470, 32)
Affinity DataIC50: 2.60nMpH: 7.5Assay Description:Membranes were prepared from CHO cells expressing human S1P1. Cells were dissociated in buffer containing 20 mM HEPES, pH 7.5, 50 mM NaCl, 2 mM EDTA ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/16/2015
Entry Details
US Patent

TargetSphingosine 1-phosphate receptor 1(Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 131719BDBM131719(US8835470, 93)
Affinity DataIC50: 2.90nMpH: 7.5Assay Description:Membranes were prepared from CHO cells expressing human S1P1. Cells were dissociated in buffer containing 20 mM HEPES, pH 7.5, 50 mM NaCl, 2 mM EDTA ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/16/2015
Entry Details
US Patent

TargetSphingosine 1-phosphate receptor 1(Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 131712BDBM131712(US8835470, 62)
Affinity DataIC50: 3.20nMpH: 7.5Assay Description:Membranes were prepared from CHO cells expressing human S1P1. Cells were dissociated in buffer containing 20 mM HEPES, pH 7.5, 50 mM NaCl, 2 mM EDTA ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/16/2015
Entry Details
US Patent

TargetSphingosine 1-phosphate receptor 1(Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 131706BDBM131706(US8835470, 30)
Affinity DataIC50: 4.5nMpH: 7.5Assay Description:Membranes were prepared from CHO cells expressing human S1P1. Cells were dissociated in buffer containing 20 mM HEPES, pH 7.5, 50 mM NaCl, 2 mM EDTA ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/16/2015
Entry Details
US Patent

TargetSphingosine 1-phosphate receptor 1(Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 131707BDBM131707(US8835470, 31)
Affinity DataIC50: 4.5nMpH: 7.5Assay Description:Membranes were prepared from CHO cells expressing human S1P1. Cells were dissociated in buffer containing 20 mM HEPES, pH 7.5, 50 mM NaCl, 2 mM EDTA ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/16/2015
Entry Details
US Patent

TargetSphingosine 1-phosphate receptor 1(Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 131723BDBM131723(US8835470, 137)
Affinity DataIC50: 4.90nMpH: 7.5Assay Description:Membranes were prepared from CHO cells expressing human S1P1. Cells were dissociated in buffer containing 20 mM HEPES, pH 7.5, 50 mM NaCl, 2 mM EDTA ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/16/2015
Entry Details
US Patent

TargetSphingosine 1-phosphate receptor 1(Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 131702BDBM131702(US8835470, 17)
Affinity DataIC50: 6.70nMpH: 7.5Assay Description:Membranes were prepared from CHO cells expressing human S1P1. Cells were dissociated in buffer containing 20 mM HEPES, pH 7.5, 50 mM NaCl, 2 mM EDTA ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/16/2015
Entry Details
US Patent

TargetSphingosine 1-phosphate receptor 1(Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 131711BDBM131711(US8835470, 61)
Affinity DataIC50: 8.5nMpH: 7.5Assay Description:Membranes were prepared from CHO cells expressing human S1P1. Cells were dissociated in buffer containing 20 mM HEPES, pH 7.5, 50 mM NaCl, 2 mM EDTA ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/16/2015
Entry Details
US Patent

TargetSphingosine 1-phosphate receptor 1(Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 131718BDBM131718(US8835470, 90)
Affinity DataIC50: 13nMpH: 7.5Assay Description:Membranes were prepared from CHO cells expressing human S1P1. Cells were dissociated in buffer containing 20 mM HEPES, pH 7.5, 50 mM NaCl, 2 mM EDTA ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/16/2015
Entry Details
US Patent

TargetSphingosine 1-phosphate receptor 1(Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 131713BDBM131713(US8835470, 67)
Affinity DataIC50: 17nMpH: 7.5Assay Description:Membranes were prepared from CHO cells expressing human S1P1. Cells were dissociated in buffer containing 20 mM HEPES, pH 7.5, 50 mM NaCl, 2 mM EDTA ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/16/2015
Entry Details
US Patent

TargetSphingosine 1-phosphate receptor 1(Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 131717BDBM131717(US8835470, 88)
Affinity DataIC50: 29nMpH: 7.5Assay Description:Membranes were prepared from CHO cells expressing human S1P1. Cells were dissociated in buffer containing 20 mM HEPES, pH 7.5, 50 mM NaCl, 2 mM EDTA ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/16/2015
Entry Details
US Patent

TargetSphingosine 1-phosphate receptor 1(Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 131703BDBM131703(US8835470, 22)
Affinity DataIC50: 29nMpH: 7.5Assay Description:Membranes were prepared from CHO cells expressing human S1P1. Cells were dissociated in buffer containing 20 mM HEPES, pH 7.5, 50 mM NaCl, 2 mM EDTA ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/16/2015
Entry Details
US Patent

TargetSphingosine 1-phosphate receptor 1(Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 131710BDBM131710(US8835470, 51)
Affinity DataIC50: 31nMpH: 7.5Assay Description:Membranes were prepared from CHO cells expressing human S1P1. Cells were dissociated in buffer containing 20 mM HEPES, pH 7.5, 50 mM NaCl, 2 mM EDTA ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/16/2015
Entry Details
US Patent

TargetSphingosine 1-phosphate receptor 1(Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 131722BDBM131722(US8835470, 132)
Affinity DataIC50: 42nMpH: 7.5Assay Description:Membranes were prepared from CHO cells expressing human S1P1. Cells were dissociated in buffer containing 20 mM HEPES, pH 7.5, 50 mM NaCl, 2 mM EDTA ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/16/2015
Entry Details
US Patent

TargetSphingosine 1-phosphate receptor 1(Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 131720BDBM131720(US8835470, 116)
Affinity DataIC50: 43nMpH: 7.5Assay Description:Membranes were prepared from CHO cells expressing human S1P1. Cells were dissociated in buffer containing 20 mM HEPES, pH 7.5, 50 mM NaCl, 2 mM EDTA ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/16/2015
Entry Details
US Patent

TargetSphingosine 1-phosphate receptor 1(Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 131716BDBM131716(US8835470, 86)
Affinity DataIC50: 180nMpH: 7.5Assay Description:Membranes were prepared from CHO cells expressing human S1P1. Cells were dissociated in buffer containing 20 mM HEPES, pH 7.5, 50 mM NaCl, 2 mM EDTA ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/16/2015
Entry Details
US Patent

TargetSphingosine 1-phosphate receptor 1(Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 131724BDBM131724(US8835470, 152)
Affinity DataIC50: 260nMpH: 7.5Assay Description:Membranes were prepared from CHO cells expressing human S1P1. Cells were dissociated in buffer containing 20 mM HEPES, pH 7.5, 50 mM NaCl, 2 mM EDTA ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/16/2015
Entry Details
US Patent

TargetSphingosine 1-phosphate receptor 1(Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 131704BDBM131704(US8835470, 24)
Affinity DataIC50: 350nMpH: 7.5Assay Description:Membranes were prepared from CHO cells expressing human S1P1. Cells were dissociated in buffer containing 20 mM HEPES, pH 7.5, 50 mM NaCl, 2 mM EDTA ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/16/2015
Entry Details
US Patent

TargetSphingosine 1-phosphate receptor 1(Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 131705BDBM131705(US8835470, 26)
Affinity DataIC50: 910nMpH: 7.5Assay Description:Membranes were prepared from CHO cells expressing human S1P1. Cells were dissociated in buffer containing 20 mM HEPES, pH 7.5, 50 mM NaCl, 2 mM EDTA ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/16/2015
Entry Details
US Patent