Compile Data Set for Download or QSAR
maximum 50k data
Found 7 Enz. Inhib. hit(s) with all data for entry = 6479
TargetNAD-dependent protein deacetylase sirtuin-1(Homo sapiens (Human))
Ikerchem

US Patent
LigandPNGBDBM131030(US8835659, 11)
Affinity DataIC50:  1.84E+3nMpH: 8.0Assay Description:50 uM of substrate peptide (acetylated AMC-labeled peptide from p53 residues 379-382, RHKKAc, BioMol. Cat. #KI-177), 91 nM of human SIRT1 (full lengt...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetNAD-dependent protein deacetylase sirtuin-1(Homo sapiens (Human))
Ikerchem

US Patent
LigandPNGBDBM50336799(5,5',5''-[1,3,6-naphthalenetriyltris(sulfonylimino...)
Affinity DataIC50:  2.62E+3nMpH: 8.0Assay Description:50 uM of substrate peptide (acetylated AMC-labeled peptide from p53 residues 379-382, RHKKAc, BioMol. Cat. #KI-177), 91 nM of human SIRT1 (full lengt...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetNAD-dependent protein deacetylase sirtuin-1(Homo sapiens (Human))
Ikerchem

US Patent
LigandPNGBDBM131032(US8835659, 15)
Affinity DataIC50:  2.28E+4nMpH: 8.0Assay Description:50 uM of substrate peptide (acetylated AMC-labeled peptide from p53 residues 379-382, RHKKAc, BioMol. Cat. #KI-177), 91 nM of human SIRT1 (full lengt...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetNAD-dependent protein deacetylase sirtuin-1(Homo sapiens (Human))
Ikerchem

US Patent
LigandPNGBDBM131031(US8835659, 13)
Affinity DataIC50:  3.67E+4nMpH: 8.0Assay Description:50 uM of substrate peptide (acetylated AMC-labeled peptide from p53 residues 379-382, RHKKAc, BioMol. Cat. #KI-177), 91 nM of human SIRT1 (full lengt...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNAD-dependent protein deacetylase sirtuin-1(Homo sapiens (Human))
Ikerchem

US Patent
LigandPNGBDBM131035(US8835659, 20)
Affinity DataIC50:  7.63E+4nMpH: 8.0Assay Description:50 uM of substrate peptide (acetylated AMC-labeled peptide from p53 residues 379-382, RHKKAc, BioMol. Cat. #KI-177), 91 nM of human SIRT1 (full lengt...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNAD-dependent protein deacetylase sirtuin-1(Homo sapiens (Human))
Ikerchem

US Patent
LigandPNGBDBM131034(US8835659, 19)
Affinity DataIC50:  1.92E+5nMpH: 8.0Assay Description:50 uM of substrate peptide (acetylated AMC-labeled peptide from p53 residues 379-382, RHKKAc, BioMol. Cat. #KI-177), 91 nM of human SIRT1 (full lengt...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetNAD-dependent protein deacetylase sirtuin-1(Homo sapiens (Human))
Ikerchem

US Patent
LigandPNGBDBM131033(US8835659, 16)
Affinity DataIC50:  2.74E+5nMpH: 8.0Assay Description:50 uM of substrate peptide (acetylated AMC-labeled peptide from p53 residues 379-382, RHKKAc, BioMol. Cat. #KI-177), 91 nM of human SIRT1 (full lengt...More data for this Ligand-Target Pair
In DepthDetails US Patent