Compile Data Set for Download or QSAR
Report error Found 749 Enz. Inhib. hit(s) with all data for entry = 6493
TargetCyclin-dependent kinase 4(Human)
Amgen

US Patent
LigandChemical structure of BindingDB Monomer ID 132266BDBM132266(US8841312, 8)
Affinity DataIC50: 0.130nMpH: 7.4 T: 2°CAssay Description:The Cdk4 and Cdk6 inhibitory activity of the compounds is measured with a kinase inhibition assay using recombinant Cdk4/CyclinD1 or Cdk6/CyclinD3 pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2015
Entry Details
US Patent

TargetCyclin-dependent kinase 4(Human)
Amgen

US Patent
LigandChemical structure of BindingDB Monomer ID 132275BDBM132275(US8841312, 17)
Affinity DataIC50: 0.320nMpH: 7.4 T: 2°CAssay Description:The Cdk4 and Cdk6 inhibitory activity of the compounds is measured with a kinase inhibition assay using recombinant Cdk4/CyclinD1 or Cdk6/CyclinD3 pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2015
Entry Details
US Patent

TargetCyclin-dependent kinase 6(Human)
Amgen

US Patent
LigandChemical structure of BindingDB Monomer ID 132275BDBM132275(US8841312, 17)
Affinity DataIC50: 0.360nMpH: 7.4 T: 2°CAssay Description:The Cdk4 and Cdk6 inhibitory activity of the compounds is measured with a kinase inhibition assay using recombinant Cdk4/CyclinD1 or Cdk6/CyclinD3 pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2015
Entry Details
US Patent

TargetCyclin-dependent kinase 6(Human)
Amgen

US Patent
LigandChemical structure of BindingDB Monomer ID 132279BDBM132279(US8841312, 21)
Affinity DataIC50: 0.410nMpH: 7.4 T: 2°CAssay Description:The Cdk4 and Cdk6 inhibitory activity of the compounds is measured with a kinase inhibition assay using recombinant Cdk4/CyclinD1 or Cdk6/CyclinD3 pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2015
Entry Details
US Patent

TargetCyclin-dependent kinase 4(Human)
Amgen

US Patent
LigandChemical structure of BindingDB Monomer ID 132261BDBM132261(US8841312, 3)
Affinity DataIC50: 0.450nMpH: 7.4 T: 2°CAssay Description:The Cdk4 and Cdk6 inhibitory activity of the compounds is measured with a kinase inhibition assay using recombinant Cdk4/CyclinD1 or Cdk6/CyclinD3 pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2015
Entry Details
US Patent

TargetCyclin-dependent kinase 6(Human)
Amgen

US Patent
LigandChemical structure of BindingDB Monomer ID 132303BDBM132303(US8841312, 46)
Affinity DataIC50: 0.75nMpH: 7.4 T: 2°CAssay Description:The Cdk4 and Cdk6 inhibitory activity of the compounds is measured with a kinase inhibition assay using recombinant Cdk4/CyclinD1 or Cdk6/CyclinD3 pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2015
Entry Details
US Patent

TargetCyclin-dependent kinase 4(Human)
Amgen

US Patent
LigandChemical structure of BindingDB Monomer ID 132293BDBM132293(US8841312, 36)
Affinity DataIC50: 0.830nMpH: 7.4 T: 2°CAssay Description:The Cdk4 and Cdk6 inhibitory activity of the compounds is measured with a kinase inhibition assay using recombinant Cdk4/CyclinD1 or Cdk6/CyclinD3 pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2015
Entry Details
US Patent

TargetCyclin-dependent kinase 4(Human)
Amgen

US Patent
LigandChemical structure of BindingDB Monomer ID 132263BDBM132263(US8841312, 5)
Affinity DataIC50: 0.910nMpH: 7.4 T: 2°CAssay Description:The Cdk4 and Cdk6 inhibitory activity of the compounds is measured with a kinase inhibition assay using recombinant Cdk4/CyclinD1 or Cdk6/CyclinD3 pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2015
Entry Details
US Patent

TargetCyclin-dependent kinase 4(Human)
Amgen

US Patent
LigandChemical structure of BindingDB Monomer ID 132281BDBM132281(US8841312, 24)
Affinity DataIC50: 0.940nMpH: 7.4 T: 2°CAssay Description:The Cdk4 and Cdk6 inhibitory activity of the compounds is measured with a kinase inhibition assay using recombinant Cdk4/CyclinD1 or Cdk6/CyclinD3 pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2015
Entry Details
US Patent

TargetCyclin-dependent kinase 4(Human)
Amgen

US Patent
LigandChemical structure of BindingDB Monomer ID 132311BDBM132311(US8841312, 56)
Affinity DataIC50: 0.970nMpH: 7.4 T: 2°CAssay Description:The Cdk4 and Cdk6 inhibitory activity of the compounds is measured with a kinase inhibition assay using recombinant Cdk4/CyclinD1 or Cdk6/CyclinD3 pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2015
Entry Details
US Patent

TargetCyclin-dependent kinase 4(Human)
Amgen

US Patent
LigandChemical structure of BindingDB Monomer ID 132732BDBM132732(US8841312, 258a)
Affinity DataIC50: 1nMpH: 7.4 T: 2°CAssay Description:The Cdk4 and Cdk6 inhibitory activity of the compounds is measured with a kinase inhibition assay using recombinant Cdk4/CyclinD1 or Cdk6/CyclinD3 pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2015
Entry Details
US Patent

TargetCyclin-dependent kinase 4(Human)
Amgen

US Patent
LigandChemical structure of BindingDB Monomer ID 132279BDBM132279(US8841312, 21)
Affinity DataIC50: 1nMpH: 7.4 T: 2°CAssay Description:The Cdk4 and Cdk6 inhibitory activity of the compounds is measured with a kinase inhibition assay using recombinant Cdk4/CyclinD1 or Cdk6/CyclinD3 pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2015
Entry Details
US Patent

TargetCyclin-dependent kinase 4(Human)
Amgen

US Patent
LigandChemical structure of BindingDB Monomer ID 132399BDBM132399(US8841312, 145)
Affinity DataIC50: 1nMpH: 7.4 T: 2°CAssay Description:The Cdk4 and Cdk6 inhibitory activity of the compounds is measured with a kinase inhibition assay using recombinant Cdk4/CyclinD1 or Cdk6/CyclinD3 pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2015
Entry Details
US Patent

TargetCyclin-dependent kinase 4(Human)
Amgen

US Patent
LigandChemical structure of BindingDB Monomer ID 132471BDBM132471(US8841312, 220)
Affinity DataIC50: 1nMpH: 7.4 T: 2°CAssay Description:The Cdk4 and Cdk6 inhibitory activity of the compounds is measured with a kinase inhibition assay using recombinant Cdk4/CyclinD1 or Cdk6/CyclinD3 pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2015
Entry Details
US Patent

TargetCyclin-dependent kinase 4(Human)
Amgen

US Patent
LigandChemical structure of BindingDB Monomer ID 132271BDBM132271(US8841312, 13)
Affinity DataIC50: 1nMpH: 7.4 T: 2°CAssay Description:The Cdk4 and Cdk6 inhibitory activity of the compounds is measured with a kinase inhibition assay using recombinant Cdk4/CyclinD1 or Cdk6/CyclinD3 pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2015
Entry Details
US Patent

TargetCyclin-dependent kinase 4(Human)
Amgen

US Patent
LigandChemical structure of BindingDB Monomer ID 132406BDBM132406(US8841312, 153)
Affinity DataIC50: 1nMpH: 7.4 T: 2°CAssay Description:The Cdk4 and Cdk6 inhibitory activity of the compounds is measured with a kinase inhibition assay using recombinant Cdk4/CyclinD1 or Cdk6/CyclinD3 pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2015
Entry Details
US Patent

TargetCyclin-dependent kinase 6(Human)
Amgen

US Patent
LigandChemical structure of BindingDB Monomer ID 132266BDBM132266(US8841312, 8)
Affinity DataIC50: 1.10nMpH: 7.4 T: 2°CAssay Description:The Cdk4 and Cdk6 inhibitory activity of the compounds is measured with a kinase inhibition assay using recombinant Cdk4/CyclinD1 or Cdk6/CyclinD3 pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2015
Entry Details
US Patent

TargetCyclin-dependent kinase 6(Human)
Amgen

US Patent
LigandChemical structure of BindingDB Monomer ID 50001539BDBM50001539(CHEMBL3237704 | US8841312, 204)
Affinity DataIC50: 1.10nMpH: 7.4 T: 2°CAssay Description:The Cdk4 and Cdk6 inhibitory activity of the compounds is measured with a kinase inhibition assay using recombinant Cdk4/CyclinD1 or Cdk6/CyclinD3 pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2015
Entry Details
US Patent

TargetCyclin-dependent kinase 6(Human)
Amgen

US Patent
LigandChemical structure of BindingDB Monomer ID 132294BDBM132294(US8841312, 37)
Affinity DataIC50: 1.20nMpH: 7.4 T: 2°CAssay Description:The Cdk4 and Cdk6 inhibitory activity of the compounds is measured with a kinase inhibition assay using recombinant Cdk4/CyclinD1 or Cdk6/CyclinD3 pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2015
Entry Details
US Patent

TargetCyclin-dependent kinase 4(Human)
Amgen

US Patent
LigandChemical structure of BindingDB Monomer ID 132392BDBM132392(US8841312, 138)
Affinity DataIC50: 1.20nMpH: 7.4 T: 2°CAssay Description:The Cdk4 and Cdk6 inhibitory activity of the compounds is measured with a kinase inhibition assay using recombinant Cdk4/CyclinD1 or Cdk6/CyclinD3 pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2015
Entry Details
US Patent

TargetCyclin-dependent kinase 4(Human)
Amgen

US Patent
LigandChemical structure of BindingDB Monomer ID 50001537BDBM50001537(CHEMBL3237702 | US8841312, 55)
Affinity DataIC50: 1.20nMpH: 7.4 T: 2°CAssay Description:The Cdk4 and Cdk6 inhibitory activity of the compounds is measured with a kinase inhibition assay using recombinant Cdk4/CyclinD1 or Cdk6/CyclinD3 pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2015
Entry Details
US Patent

TargetCyclin-dependent kinase 4(Human)
Amgen

US Patent
LigandChemical structure of BindingDB Monomer ID 132321BDBM132321(US8841312, 67)
Affinity DataIC50: 1.30nMpH: 7.4 T: 2°CAssay Description:The Cdk4 and Cdk6 inhibitory activity of the compounds is measured with a kinase inhibition assay using recombinant Cdk4/CyclinD1 or Cdk6/CyclinD3 pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2015
Entry Details
US Patent

TargetCyclin-dependent kinase 4(Human)
Amgen

US Patent
LigandChemical structure of BindingDB Monomer ID 132696BDBM132696(US8841312, 446)
Affinity DataIC50: 1.30nMpH: 7.4 T: 2°CAssay Description:The Cdk4 and Cdk6 inhibitory activity of the compounds is measured with a kinase inhibition assay using recombinant Cdk4/CyclinD1 or Cdk6/CyclinD3 pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2015
Entry Details
US Patent

TargetCyclin-dependent kinase 4(Human)
Amgen

US Patent
LigandChemical structure of BindingDB Monomer ID 132507BDBM132507(US8841312, 256)
Affinity DataIC50: 1.30nMpH: 7.4 T: 2°CAssay Description:The Cdk4 and Cdk6 inhibitory activity of the compounds is measured with a kinase inhibition assay using recombinant Cdk4/CyclinD1 or Cdk6/CyclinD3 pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2015
Entry Details
US Patent

TargetCyclin-dependent kinase 4(Human)
Amgen

US Patent
LigandChemical structure of BindingDB Monomer ID 132280BDBM132280(US8841312, 22)
Affinity DataIC50: 1.30nMpH: 7.4 T: 2°CAssay Description:The Cdk4 and Cdk6 inhibitory activity of the compounds is measured with a kinase inhibition assay using recombinant Cdk4/CyclinD1 or Cdk6/CyclinD3 pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2015
Entry Details
US Patent

TargetCyclin-dependent kinase 6(Human)
Amgen

US Patent
LigandChemical structure of BindingDB Monomer ID 132265BDBM132265(US8841312, 7)
Affinity DataIC50: 1.30nMpH: 7.4 T: 2°CAssay Description:The Cdk4 and Cdk6 inhibitory activity of the compounds is measured with a kinase inhibition assay using recombinant Cdk4/CyclinD1 or Cdk6/CyclinD3 pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2015
Entry Details
US Patent

TargetCyclin-dependent kinase 4(Human)
Amgen

US Patent
LigandChemical structure of BindingDB Monomer ID 132469BDBM132469(US8841312, 218)
Affinity DataIC50: 1.39nMpH: 7.4 T: 2°CAssay Description:The Cdk4 and Cdk6 inhibitory activity of the compounds is measured with a kinase inhibition assay using recombinant Cdk4/CyclinD1 or Cdk6/CyclinD3 pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2015
Entry Details
US Patent

TargetCyclin-dependent kinase 4(Human)
Amgen

US Patent
LigandChemical structure of BindingDB Monomer ID 132548BDBM132548(US8841312, 297)
Affinity DataIC50: 1.40nMpH: 7.4 T: 2°CAssay Description:The Cdk4 and Cdk6 inhibitory activity of the compounds is measured with a kinase inhibition assay using recombinant Cdk4/CyclinD1 or Cdk6/CyclinD3 pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2015
Entry Details
US Patent

TargetCyclin-dependent kinase 4(Human)
Amgen

US Patent
LigandChemical structure of BindingDB Monomer ID 132329BDBM132329(US8841312, 75)
Affinity DataIC50: 1.40nMpH: 7.4 T: 2°CAssay Description:The Cdk4 and Cdk6 inhibitory activity of the compounds is measured with a kinase inhibition assay using recombinant Cdk4/CyclinD1 or Cdk6/CyclinD3 pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2015
Entry Details
US Patent

TargetCyclin-dependent kinase 4(Human)
Amgen

US Patent
LigandChemical structure of BindingDB Monomer ID 132472BDBM132472(US8841312, 221)
Affinity DataIC50: 1.40nMpH: 7.4 T: 2°CAssay Description:The Cdk4 and Cdk6 inhibitory activity of the compounds is measured with a kinase inhibition assay using recombinant Cdk4/CyclinD1 or Cdk6/CyclinD3 pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2015
Entry Details
US Patent

TargetCyclin-dependent kinase 4(Human)
Amgen

US Patent
LigandChemical structure of BindingDB Monomer ID 132265BDBM132265(US8841312, 7)
Affinity DataIC50: 1.40nMpH: 7.4 T: 2°CAssay Description:The Cdk4 and Cdk6 inhibitory activity of the compounds is measured with a kinase inhibition assay using recombinant Cdk4/CyclinD1 or Cdk6/CyclinD3 pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2015
Entry Details
US Patent

TargetCyclin-dependent kinase 6(Human)
Amgen

US Patent
LigandChemical structure of BindingDB Monomer ID 132276BDBM132276(US8841312, 18)
Affinity DataIC50: 1.5nMpH: 7.4 T: 2°CAssay Description:The Cdk4 and Cdk6 inhibitory activity of the compounds is measured with a kinase inhibition assay using recombinant Cdk4/CyclinD1 or Cdk6/CyclinD3 pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2015
Entry Details
US Patent

TargetCyclin-dependent kinase 4(Human)
Amgen

US Patent
LigandChemical structure of BindingDB Monomer ID 132692BDBM132692(US8841312, 442)
Affinity DataIC50: 1.5nMpH: 7.4 T: 2°CAssay Description:The Cdk4 and Cdk6 inhibitory activity of the compounds is measured with a kinase inhibition assay using recombinant Cdk4/CyclinD1 or Cdk6/CyclinD3 pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2015
Entry Details
US Patent

TargetCyclin-dependent kinase 4(Human)
Amgen

US Patent
LigandChemical structure of BindingDB Monomer ID 132264BDBM132264(US8841312, 6)
Affinity DataIC50: 1.5nMpH: 7.4 T: 2°CAssay Description:The Cdk4 and Cdk6 inhibitory activity of the compounds is measured with a kinase inhibition assay using recombinant Cdk4/CyclinD1 or Cdk6/CyclinD3 pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2015
Entry Details
US Patent

TargetCyclin-dependent kinase 4(Human)
Amgen

US Patent
LigandChemical structure of BindingDB Monomer ID 132276BDBM132276(US8841312, 18)
Affinity DataIC50: 1.60nMpH: 7.4 T: 2°CAssay Description:The Cdk4 and Cdk6 inhibitory activity of the compounds is measured with a kinase inhibition assay using recombinant Cdk4/CyclinD1 or Cdk6/CyclinD3 pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2015
Entry Details
US Patent

TargetCyclin-dependent kinase 4(Human)
Amgen

US Patent
LigandChemical structure of BindingDB Monomer ID 132368BDBM132368(US8841312, 114)
Affinity DataIC50: 1.60nMpH: 7.4 T: 2°CAssay Description:The Cdk4 and Cdk6 inhibitory activity of the compounds is measured with a kinase inhibition assay using recombinant Cdk4/CyclinD1 or Cdk6/CyclinD3 pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2015
Entry Details
US Patent

TargetCyclin-dependent kinase 4(Human)
Amgen

US Patent
LigandChemical structure of BindingDB Monomer ID 132305BDBM132305(US8841312, 48)
Affinity DataIC50: 1.60nMpH: 7.4 T: 2°CAssay Description:The Cdk4 and Cdk6 inhibitory activity of the compounds is measured with a kinase inhibition assay using recombinant Cdk4/CyclinD1 or Cdk6/CyclinD3 pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2015
Entry Details
US Patent

TargetCyclin-dependent kinase 4(Human)
Amgen

US Patent
LigandChemical structure of BindingDB Monomer ID 132283BDBM132283(US8841312, 26)
Affinity DataIC50: 1.60nMpH: 7.4 T: 2°CAssay Description:The Cdk4 and Cdk6 inhibitory activity of the compounds is measured with a kinase inhibition assay using recombinant Cdk4/CyclinD1 or Cdk6/CyclinD3 pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2015
Entry Details
US Patent

TargetCyclin-dependent kinase 4(Human)
Amgen

US Patent
LigandChemical structure of BindingDB Monomer ID 132691BDBM132691(US8841312, 441)
Affinity DataIC50: 1.70nMpH: 7.4 T: 2°CAssay Description:The Cdk4 and Cdk6 inhibitory activity of the compounds is measured with a kinase inhibition assay using recombinant Cdk4/CyclinD1 or Cdk6/CyclinD3 pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2015
Entry Details
US Patent

TargetCyclin-dependent kinase 4(Human)
Amgen

US Patent
LigandChemical structure of BindingDB Monomer ID 132726BDBM132726(US8841312, 476)
Affinity DataIC50: 1.70nMpH: 7.4 T: 2°CAssay Description:The Cdk4 and Cdk6 inhibitory activity of the compounds is measured with a kinase inhibition assay using recombinant Cdk4/CyclinD1 or Cdk6/CyclinD3 pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2015
Entry Details
US Patent

TargetCyclin-dependent kinase 4(Human)
Amgen

US Patent
LigandChemical structure of BindingDB Monomer ID 132315BDBM132315(US8841312, 61)
Affinity DataIC50: 1.70nMpH: 7.4 T: 2°CAssay Description:The Cdk4 and Cdk6 inhibitory activity of the compounds is measured with a kinase inhibition assay using recombinant Cdk4/CyclinD1 or Cdk6/CyclinD3 pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2015
Entry Details
US Patent

TargetCyclin-dependent kinase 4(Human)
Amgen

US Patent
LigandChemical structure of BindingDB Monomer ID 132396BDBM132396(US8841312, 142)
Affinity DataIC50: 1.80nMpH: 7.4 T: 2°CAssay Description:The Cdk4 and Cdk6 inhibitory activity of the compounds is measured with a kinase inhibition assay using recombinant Cdk4/CyclinD1 or Cdk6/CyclinD3 pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2015
Entry Details
US Patent

TargetCyclin-dependent kinase 4(Human)
Amgen

US Patent
LigandChemical structure of BindingDB Monomer ID 132459BDBM132459(US8841312, 208)
Affinity DataIC50: 1.80nMpH: 7.4 T: 2°CAssay Description:The Cdk4 and Cdk6 inhibitory activity of the compounds is measured with a kinase inhibition assay using recombinant Cdk4/CyclinD1 or Cdk6/CyclinD3 pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2015
Entry Details
US Patent

TargetCyclin-dependent kinase 4(Human)
Amgen

US Patent
LigandChemical structure of BindingDB Monomer ID 132439BDBM132439(US8841312, 186A)
Affinity DataIC50: 1.90nMpH: 7.4 T: 2°CAssay Description:The Cdk4 and Cdk6 inhibitory activity of the compounds is measured with a kinase inhibition assay using recombinant Cdk4/CyclinD1 or Cdk6/CyclinD3 pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2015
Entry Details
US Patent

TargetCyclin-dependent kinase 4(Human)
Amgen

US Patent
LigandChemical structure of BindingDB Monomer ID 132694BDBM132694(US8841312, 444)
Affinity DataIC50: 1.90nMpH: 7.4 T: 2°CAssay Description:The Cdk4 and Cdk6 inhibitory activity of the compounds is measured with a kinase inhibition assay using recombinant Cdk4/CyclinD1 or Cdk6/CyclinD3 pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2015
Entry Details
US Patent

TargetCyclin-dependent kinase 4(Human)
Amgen

US Patent
LigandChemical structure of BindingDB Monomer ID 132363BDBM132363(US8841312, 109)
Affinity DataIC50: 1.90nMpH: 7.4 T: 2°CAssay Description:The Cdk4 and Cdk6 inhibitory activity of the compounds is measured with a kinase inhibition assay using recombinant Cdk4/CyclinD1 or Cdk6/CyclinD3 pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2015
Entry Details
US Patent

TargetCyclin-dependent kinase 4(Human)
Amgen

US Patent
LigandChemical structure of BindingDB Monomer ID 132370BDBM132370(US8841312, 116)
Affinity DataIC50: 2nMpH: 7.4 T: 2°CAssay Description:The Cdk4 and Cdk6 inhibitory activity of the compounds is measured with a kinase inhibition assay using recombinant Cdk4/CyclinD1 or Cdk6/CyclinD3 pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2015
Entry Details
US Patent

TargetCyclin-dependent kinase 4(Human)
Amgen

US Patent
LigandChemical structure of BindingDB Monomer ID 132433BDBM132433(US8841312, 180)
Affinity DataIC50: 2nMpH: 7.4 T: 2°CAssay Description:The Cdk4 and Cdk6 inhibitory activity of the compounds is measured with a kinase inhibition assay using recombinant Cdk4/CyclinD1 or Cdk6/CyclinD3 pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2015
Entry Details
US Patent

TargetCyclin-dependent kinase 6(Human)
Amgen

US Patent
LigandChemical structure of BindingDB Monomer ID 132439BDBM132439(US8841312, 186A)
Affinity DataIC50: 2nMpH: 7.4 T: 2°CAssay Description:The Cdk4 and Cdk6 inhibitory activity of the compounds is measured with a kinase inhibition assay using recombinant Cdk4/CyclinD1 or Cdk6/CyclinD3 pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2015
Entry Details
US Patent

TargetCyclin-dependent kinase 4(Human)
Amgen

US Patent
LigandChemical structure of BindingDB Monomer ID 132303BDBM132303(US8841312, 46)
Affinity DataIC50: 2nMpH: 7.4 T: 2°CAssay Description:The Cdk4 and Cdk6 inhibitory activity of the compounds is measured with a kinase inhibition assay using recombinant Cdk4/CyclinD1 or Cdk6/CyclinD3 pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2015
Entry Details
US Patent

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