Compile Data Set for Download or QSAR
Report error Found 35 Enz. Inhib. hit(s) with all data for entry = 6513
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 135609BDBM135609(US8846000, G-2)
Affinity DataKi:  0.0240nMAssay Description:The activity of the compounds in accordance with the present invention as PDE10 inhibitors may be readily determined without undue experimentation us...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/9/2015
Entry Details
US Patent

TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 135597BDBM135597(US8846000, 1-13)
Affinity DataKi:  0.0550nMAssay Description:The activity of the compounds in accordance with the present invention as PDE10 inhibitors may be readily determined without undue experimentation us...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/9/2015
Entry Details
US Patent

TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 135600BDBM135600(US8846000, 1-16)
Affinity DataKi:  0.0730nMAssay Description:The activity of the compounds in accordance with the present invention as PDE10 inhibitors may be readily determined without undue experimentation us...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/9/2015
Entry Details
US Patent

TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 135598BDBM135598(US8846000, 1-14)
Affinity DataKi:  0.0770nMAssay Description:The activity of the compounds in accordance with the present invention as PDE10 inhibitors may be readily determined without undue experimentation us...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/9/2015
Entry Details
US Patent

TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 135608BDBM135608(US8846000, G-1)
Affinity DataKi:  0.100nMAssay Description:The activity of the compounds in accordance with the present invention as PDE10 inhibitors may be readily determined without undue experimentation us...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/9/2015
Entry Details
US Patent

TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 135606BDBM135606(US8846000, 1-24)
Affinity DataKi:  0.100nMAssay Description:The activity of the compounds in accordance with the present invention as PDE10 inhibitors may be readily determined without undue experimentation us...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/9/2015
Entry Details
US Patent

TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 135614BDBM135614(US8846000, D-7)
Affinity DataKi:  0.150nMAssay Description:The activity of the compounds in accordance with the present invention as PDE10 inhibitors may be readily determined without undue experimentation us...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/9/2015
Entry Details
US Patent

TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 135596BDBM135596(US8846000, 1-12)
Affinity DataKi:  0.190nMAssay Description:The activity of the compounds in accordance with the present invention as PDE10 inhibitors may be readily determined without undue experimentation us...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/9/2015
Entry Details
US Patent

TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 135613BDBM135613(US8846000, D-6)
Affinity DataKi:  0.280nMAssay Description:The activity of the compounds in accordance with the present invention as PDE10 inhibitors may be readily determined without undue experimentation us...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/9/2015
Entry Details
US Patent

TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 135599BDBM135599(US8846000, 1-15)
Affinity DataKi:  0.480nMAssay Description:The activity of the compounds in accordance with the present invention as PDE10 inhibitors may be readily determined without undue experimentation us...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/9/2015
Entry Details
US Patent

TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 135595BDBM135595(US8846000, 1-11)
Affinity DataKi:  0.560nMAssay Description:The activity of the compounds in accordance with the present invention as PDE10 inhibitors may be readily determined without undue experimentation us...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/9/2015
Entry Details
US Patent

TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 135591BDBM135591(US8846000, 1-7)
Affinity DataKi:  0.700nMAssay Description:The activity of the compounds in accordance with the present invention as PDE10 inhibitors may be readily determined without undue experimentation us...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/9/2015
Entry Details
US Patent

TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 135602BDBM135602(US8846000, 1-19)
Affinity DataKi:  0.790nMAssay Description:The activity of the compounds in accordance with the present invention as PDE10 inhibitors may be readily determined without undue experimentation us...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/9/2015
Entry Details
US Patent

TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 135612BDBM135612(US8846000, D-5)
Affinity DataKi:  0.830nMAssay Description:The activity of the compounds in accordance with the present invention as PDE10 inhibitors may be readily determined without undue experimentation us...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/9/2015
Entry Details
US Patent

TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 50398004BDBM50398004(CHEMBL2180401)
Affinity DataKi:  0.950nMAssay Description:The activity of the compounds in accordance with the present invention as PDE10 inhibitors may be readily determined without undue experimentation us...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/9/2015
Entry Details
US Patent

TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 135604BDBM135604(US8846000, 1-21)
Affinity DataKi:  1nMAssay Description:The activity of the compounds in accordance with the present invention as PDE10 inhibitors may be readily determined without undue experimentation us...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/9/2015
Entry Details
US Patent

TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 135592BDBM135592(US8846000, 1-8)
Affinity DataKi:  1.20nMAssay Description:The activity of the compounds in accordance with the present invention as PDE10 inhibitors may be readily determined without undue experimentation us...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/9/2015
Entry Details
US Patent

TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 135603BDBM135603(US8846000, 1-20)
Affinity DataKi:  1.30nMAssay Description:The activity of the compounds in accordance with the present invention as PDE10 inhibitors may be readily determined without undue experimentation us...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/9/2015
Entry Details
US Patent

TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 135611BDBM135611(US8846000, C-2)
Affinity DataKi:  1.80nMAssay Description:The activity of the compounds in accordance with the present invention as PDE10 inhibitors may be readily determined without undue experimentation us...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/9/2015
Entry Details
US Patent

TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 50398008BDBM50398008(CHEMBL2180426)
Affinity DataKi:  2nMAssay Description:The activity of the compounds in accordance with the present invention as PDE10 inhibitors may be readily determined without undue experimentation us...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/9/2015
Entry Details
US Patent

TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 135605BDBM135605(US8846000, 1-22)
Affinity DataKi:  2.08nMAssay Description:The activity of the compounds in accordance with the present invention as PDE10 inhibitors may be readily determined without undue experimentation us...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/9/2015
Entry Details
US Patent

TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 135607BDBM135607(US8846000, 1-25)
Affinity DataKi:  11nMAssay Description:The activity of the compounds in accordance with the present invention as PDE10 inhibitors may be readily determined without undue experimentation us...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/9/2015
Entry Details
US Patent

TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 135586BDBM135586(US8846000, 1-2)
Affinity DataKi:  14nMAssay Description:The activity of the compounds in accordance with the present invention as PDE10 inhibitors may be readily determined without undue experimentation us...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/9/2015
Entry Details
US Patent

TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 135610BDBM135610(US8846000, B-2)
Affinity DataKi:  22nMAssay Description:The activity of the compounds in accordance with the present invention as PDE10 inhibitors may be readily determined without undue experimentation us...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/9/2015
Entry Details
US Patent

TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 135589BDBM135589(US8846000, 1-5)
Affinity DataKi:  26nMAssay Description:The activity of the compounds in accordance with the present invention as PDE10 inhibitors may be readily determined without undue experimentation us...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/9/2015
Entry Details
US Patent

TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 135590BDBM135590(US8846000, 1-6)
Affinity DataKi:  33nMAssay Description:The activity of the compounds in accordance with the present invention as PDE10 inhibitors may be readily determined without undue experimentation us...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/9/2015
Entry Details
US Patent

TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 135585BDBM135585(US8846000, 1-1)
Affinity DataKi:  39nMAssay Description:The activity of the compounds in accordance with the present invention as PDE10 inhibitors may be readily determined without undue experimentation us...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/9/2015
Entry Details
US Patent

TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 135593BDBM135593(US8846000, 1-9)
Affinity DataKi:  39nMAssay Description:The activity of the compounds in accordance with the present invention as PDE10 inhibitors may be readily determined without undue experimentation us...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/9/2015
Entry Details
US Patent

TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 135594BDBM135594(US8846000, 1-10)
Affinity DataKi:  48nMAssay Description:The activity of the compounds in accordance with the present invention as PDE10 inhibitors may be readily determined without undue experimentation us...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/9/2015
Entry Details
US Patent

TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 135588BDBM135588(US8846000, 1-4)
Affinity DataKi:  61nMAssay Description:The activity of the compounds in accordance with the present invention as PDE10 inhibitors may be readily determined without undue experimentation us...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/9/2015
Entry Details
US Patent

TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 135587BDBM135587(US8846000, 1-3)
Affinity DataKi:  77nMAssay Description:The activity of the compounds in accordance with the present invention as PDE10 inhibitors may be readily determined without undue experimentation us...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/9/2015
Entry Details
US Patent

TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 50398010BDBM50398010(CHEMBL2180424)
Affinity DataKi:  87nMAssay Description:The activity of the compounds in accordance with the present invention as PDE10 inhibitors may be readily determined without undue experimentation us...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/9/2015
Entry Details
US Patent

TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 135615BDBM135615(US8846000, F-1)
Affinity DataKi:  140nMAssay Description:The activity of the compounds in accordance with the present invention as PDE10 inhibitors may be readily determined without undue experimentation us...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/9/2015
Entry Details
US Patent

TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 135601BDBM135601(US8846000, 1-18)
Affinity DataKi:  219nMAssay Description:The activity of the compounds in accordance with the present invention as PDE10 inhibitors may be readily determined without undue experimentation us...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/9/2015
Entry Details
US Patent

TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 50398009BDBM50398009(CHEMBL2180425)
Affinity DataKi:  1.90E+3nMAssay Description:The activity of the compounds in accordance with the present invention as PDE10 inhibitors may be readily determined without undue experimentation us...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/9/2015
Entry Details
US Patent