Compile Data Set for Download or QSAR
Report error Found 372 Enz. Inhib. hit(s) with all data for entry = 6498
TargetGamma-aminobutyric acid receptor subunit alpha-5(Human)
Roche Palo Alto

US Patent
LigandChemical structure of BindingDB Monomer ID 133600BDBM133600(US8846719, 311)
Affinity DataKi:  0.100nM ΔG°:  -53.1kJ/molepH: 7.5 T: 2°CAssay Description:Radioligand binding assays were carried out in a volume of 200 mL (96-well plates) which contained 100 mL of cell memebranes, [3H]flumazenil at a con...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/3/2015
Entry Details
US Patent

TargetGamma-aminobutyric acid receptor subunit alpha-5(Human)
Roche Palo Alto

US Patent
LigandChemical structure of BindingDB Monomer ID 133597BDBM133597(US8846719, 308)
Affinity DataKi:  0.200nM ΔG°:  -51.5kJ/molepH: 7.5 T: 2°CAssay Description:Radioligand binding assays were carried out in a volume of 200 mL (96-well plates) which contained 100 mL of cell memebranes, [3H]flumazenil at a con...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/3/2015
Entry Details
US Patent

TargetGamma-aminobutyric acid receptor subunit alpha-5(Human)
Roche Palo Alto

US Patent
LigandChemical structure of BindingDB Monomer ID 10517BDBM10517(US8846719, 302)
Affinity DataKi:  0.300nM ΔG°:  -50.5kJ/molepH: 7.5 T: 2°CAssay Description:Radioligand binding assays were carried out in a volume of 200 mL (96-well plates) which contained 100 mL of cell memebranes, [3H]flumazenil at a con...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/3/2015
Entry Details
US Patent

TargetGamma-aminobutyric acid receptor subunit alpha-5(Human)
Roche Palo Alto

US Patent
LigandChemical structure of BindingDB Monomer ID 10521BDBM10521(US8846719, 303)
Affinity DataKi:  0.300nM ΔG°:  -50.5kJ/molepH: 7.5 T: 2°CAssay Description:Radioligand binding assays were carried out in a volume of 200 mL (96-well plates) which contained 100 mL of cell memebranes, [3H]flumazenil at a con...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/3/2015
Entry Details
US Patent

TargetGamma-aminobutyric acid receptor subunit alpha-5(Human)
Roche Palo Alto

US Patent
LigandChemical structure of BindingDB Monomer ID 10467BDBM10467(US8846719, 294)
Affinity DataKi:  0.300nM ΔG°:  -50.5kJ/molepH: 7.5 T: 2°CAssay Description:Radioligand binding assays were carried out in a volume of 200 mL (96-well plates) which contained 100 mL of cell memebranes, [3H]flumazenil at a con...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/3/2015
Entry Details
US Patent

TargetGamma-aminobutyric acid receptor subunit alpha-5(Human)
Roche Palo Alto

US Patent
LigandChemical structure of BindingDB Monomer ID 10673BDBM10673(US8846719, 289)
Affinity DataKi:  0.300nM ΔG°:  -50.5kJ/molepH: 7.5 T: 2°CAssay Description:Radioligand binding assays were carried out in a volume of 200 mL (96-well plates) which contained 100 mL of cell memebranes, [3H]flumazenil at a con...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/3/2015
Entry Details
US Patent

TargetGamma-aminobutyric acid receptor subunit alpha-5(Human)
Roche Palo Alto

US Patent
LigandChemical structure of BindingDB Monomer ID 133596BDBM133596(US8846719, 306)
Affinity DataKi:  0.300nM ΔG°:  -50.5kJ/molepH: 7.5 T: 2°CAssay Description:Radioligand binding assays were carried out in a volume of 200 mL (96-well plates) which contained 100 mL of cell memebranes, [3H]flumazenil at a con...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/3/2015
Entry Details
US Patent

TargetGamma-aminobutyric acid receptor subunit alpha-5(Human)
Roche Palo Alto

US Patent
LigandChemical structure of BindingDB Monomer ID 10484BDBM10484(US8846719, 301 | US11091471, Example RO-301 | US20...)
Affinity DataKi:  0.300nM ΔG°:  -50.5kJ/molepH: 7.5 T: 2°CAssay Description:Radioligand binding assays were carried out in a volume of 200 mL (96-well plates) which contained 100 mL of cell memebranes, [3H]flumazenil at a con...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/3/2015
Entry Details
US Patent

TargetGamma-aminobutyric acid receptor subunit alpha-5(Human)
Roche Palo Alto

US Patent
LigandChemical structure of BindingDB Monomer ID 10711BDBM10711(US8846719, 292)
Affinity DataKi:  0.400nM ΔG°:  -49.9kJ/molepH: 7.5 T: 2°CAssay Description:Radioligand binding assays were carried out in a volume of 200 mL (96-well plates) which contained 100 mL of cell memebranes, [3H]flumazenil at a con...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/3/2015
Entry Details
US Patent

TargetGamma-aminobutyric acid receptor subunit alpha-5(Human)
Roche Palo Alto

US Patent
LigandChemical structure of BindingDB Monomer ID 133578BDBM133578(US8846719, 270)
Affinity DataKi:  0.400nM ΔG°:  -49.9kJ/molepH: 7.5 T: 2°CAssay Description:Radioligand binding assays were carried out in a volume of 200 mL (96-well plates) which contained 100 mL of cell memebranes, [3H]flumazenil at a con...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/3/2015
Entry Details
US Patent

TargetGamma-aminobutyric acid receptor subunit alpha-5(Human)
Roche Palo Alto

US Patent
LigandChemical structure of BindingDB Monomer ID 133599BDBM133599(US8846719, 310)
Affinity DataKi:  0.400nM ΔG°:  -49.9kJ/molepH: 7.5 T: 2°CAssay Description:Radioligand binding assays were carried out in a volume of 200 mL (96-well plates) which contained 100 mL of cell memebranes, [3H]flumazenil at a con...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/3/2015
Entry Details
US Patent

TargetGamma-aminobutyric acid receptor subunit alpha-5(Human)
Roche Palo Alto

US Patent
LigandChemical structure of BindingDB Monomer ID 10468BDBM10468(US8846719, 295)
Affinity DataKi:  0.400nM ΔG°:  -49.9kJ/molepH: 7.5 T: 2°CAssay Description:Radioligand binding assays were carried out in a volume of 200 mL (96-well plates) which contained 100 mL of cell memebranes, [3H]flumazenil at a con...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/3/2015
Entry Details
US Patent

TargetGamma-aminobutyric acid receptor subunit alpha-5(Human)
Roche Palo Alto

US Patent
LigandChemical structure of BindingDB Monomer ID 10672BDBM10672(US8846719, 288)
Affinity DataKi:  0.400nM ΔG°:  -49.9kJ/molepH: 7.5 T: 2°CAssay Description:Radioligand binding assays were carried out in a volume of 200 mL (96-well plates) which contained 100 mL of cell memebranes, [3H]flumazenil at a con...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/3/2015
Entry Details
US Patent

TargetGamma-aminobutyric acid receptor subunit alpha-5(Human)
Roche Palo Alto

US Patent
LigandChemical structure of BindingDB Monomer ID 133565BDBM133565(US8846719, 257)
Affinity DataKi:  0.5nM ΔG°:  -49.3kJ/molepH: 7.5 T: 2°CAssay Description:Radioligand binding assays were carried out in a volume of 200 mL (96-well plates) which contained 100 mL of cell memebranes, [3H]flumazenil at a con...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/3/2015
Entry Details
US Patent

TargetGamma-aminobutyric acid receptor subunit alpha-5(Human)
Roche Palo Alto

US Patent
LigandChemical structure of BindingDB Monomer ID 133594BDBM133594(US8846719, 299)
Affinity DataKi:  0.5nM ΔG°:  -49.3kJ/molepH: 7.5 T: 2°CAssay Description:Radioligand binding assays were carried out in a volume of 200 mL (96-well plates) which contained 100 mL of cell memebranes, [3H]flumazenil at a con...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/3/2015
Entry Details
US Patent

TargetGamma-aminobutyric acid receptor subunit alpha-5(Human)
Roche Palo Alto

US Patent
LigandChemical structure of BindingDB Monomer ID 10667BDBM10667(US8846719, 284)
Affinity DataKi:  0.5nM ΔG°:  -49.3kJ/molepH: 7.5 T: 2°CAssay Description:Radioligand binding assays were carried out in a volume of 200 mL (96-well plates) which contained 100 mL of cell memebranes, [3H]flumazenil at a con...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/3/2015
Entry Details
US Patent

TargetGamma-aminobutyric acid receptor subunit alpha-5(Human)
Roche Palo Alto

US Patent
LigandChemical structure of BindingDB Monomer ID 133568BDBM133568(US8846719, 260)
Affinity DataKi:  0.5nM ΔG°:  -49.3kJ/molepH: 7.5 T: 2°CAssay Description:Radioligand binding assays were carried out in a volume of 200 mL (96-well plates) which contained 100 mL of cell memebranes, [3H]flumazenil at a con...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/3/2015
Entry Details
US Patent

TargetGamma-aminobutyric acid receptor subunit alpha-5(Human)
Roche Palo Alto

US Patent
LigandChemical structure of BindingDB Monomer ID 10483BDBM10483(US8846719, 297)
Affinity DataKi:  0.5nM ΔG°:  -49.3kJ/molepH: 7.5 T: 2°CAssay Description:Radioligand binding assays were carried out in a volume of 200 mL (96-well plates) which contained 100 mL of cell memebranes, [3H]flumazenil at a con...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/3/2015
Entry Details
US Patent

TargetGamma-aminobutyric acid receptor subunit alpha-5(Human)
Roche Palo Alto

US Patent
LigandChemical structure of BindingDB Monomer ID 133595BDBM133595(US8846719, 298)
Affinity DataKi:  0.600nM ΔG°:  -48.9kJ/molepH: 7.5 T: 2°CAssay Description:Radioligand binding assays were carried out in a volume of 200 mL (96-well plates) which contained 100 mL of cell memebranes, [3H]flumazenil at a con...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/3/2015
Entry Details
US Patent

TargetGamma-aminobutyric acid receptor subunit alpha-5(Human)
Roche Palo Alto

US Patent
LigandChemical structure of BindingDB Monomer ID 133542BDBM133542(US8846719, 234)
Affinity DataKi:  0.600nM ΔG°:  -48.9kJ/molepH: 7.5 T: 2°CAssay Description:Radioligand binding assays were carried out in a volume of 200 mL (96-well plates) which contained 100 mL of cell memebranes, [3H]flumazenil at a con...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/3/2015
Entry Details
US Patent

TargetGamma-aminobutyric acid receptor subunit alpha-5(Human)
Roche Palo Alto

US Patent
LigandChemical structure of BindingDB Monomer ID 133598BDBM133598(US8846719, 309)
Affinity DataKi:  0.600nM ΔG°:  -48.9kJ/molepH: 7.5 T: 2°CAssay Description:Radioligand binding assays were carried out in a volume of 200 mL (96-well plates) which contained 100 mL of cell memebranes, [3H]flumazenil at a con...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/3/2015
Entry Details
US Patent

TargetGamma-aminobutyric acid receptor subunit alpha-5(Human)
Roche Palo Alto

US Patent
LigandChemical structure of BindingDB Monomer ID 11505BDBM11505(US8846719, 307)
Affinity DataKi:  0.600nM ΔG°:  -48.9kJ/molepH: 7.5 T: 2°CAssay Description:Radioligand binding assays were carried out in a volume of 200 mL (96-well plates) which contained 100 mL of cell memebranes, [3H]flumazenil at a con...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/3/2015
Entry Details
US Patent

TargetGamma-aminobutyric acid receptor subunit alpha-5(Human)
Roche Palo Alto

US Patent
LigandChemical structure of BindingDB Monomer ID 10677BDBM10677(US8846719, 290)
Affinity DataKi:  0.600nM ΔG°:  -48.9kJ/molepH: 7.5 T: 2°CAssay Description:Radioligand binding assays were carried out in a volume of 200 mL (96-well plates) which contained 100 mL of cell memebranes, [3H]flumazenil at a con...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/3/2015
Entry Details
US Patent

TargetGamma-aminobutyric acid receptor subunit alpha-5(Human)
Roche Palo Alto

US Patent
LigandChemical structure of BindingDB Monomer ID 133593BDBM133593(US8846719, 305)
Affinity DataKi:  0.600nM ΔG°:  -48.9kJ/molepH: 7.5 T: 2°CAssay Description:Radioligand binding assays were carried out in a volume of 200 mL (96-well plates) which contained 100 mL of cell memebranes, [3H]flumazenil at a con...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/3/2015
Entry Details
US Patent

TargetGamma-aminobutyric acid receptor subunit alpha-5(Human)
Roche Palo Alto

US Patent
LigandChemical structure of BindingDB Monomer ID 133581BDBM133581(US8846719, 273)
Affinity DataKi:  0.600nM ΔG°:  -48.9kJ/molepH: 7.5 T: 2°CAssay Description:Radioligand binding assays were carried out in a volume of 200 mL (96-well plates) which contained 100 mL of cell memebranes, [3H]flumazenil at a con...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/3/2015
Entry Details
US Patent

TargetGamma-aminobutyric acid receptor subunit alpha-5(Human)
Roche Palo Alto

US Patent
LigandChemical structure of BindingDB Monomer ID 133518BDBM133518(US8846719, 208)
Affinity DataKi:  0.700nM ΔG°:  -48.6kJ/molepH: 7.5 T: 2°CAssay Description:Radioligand binding assays were carried out in a volume of 200 mL (96-well plates) which contained 100 mL of cell memebranes, [3H]flumazenil at a con...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/3/2015
Entry Details
US Patent

TargetGamma-aminobutyric acid receptor subunit alpha-5(Human)
Roche Palo Alto

US Patent
LigandChemical structure of BindingDB Monomer ID 133567BDBM133567(US8846719, 259)
Affinity DataKi:  0.700nM ΔG°:  -48.6kJ/molepH: 7.5 T: 2°CAssay Description:Radioligand binding assays were carried out in a volume of 200 mL (96-well plates) which contained 100 mL of cell memebranes, [3H]flumazenil at a con...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/3/2015
Entry Details
US Patent

TargetGamma-aminobutyric acid receptor subunit alpha-5(Human)
Roche Palo Alto

US Patent
LigandChemical structure of BindingDB Monomer ID 133422BDBM133422(US8846719, 107)
Affinity DataKi:  0.700nM ΔG°:  -48.6kJ/molepH: 7.5 T: 2°CAssay Description:Radioligand binding assays were carried out in a volume of 200 mL (96-well plates) which contained 100 mL of cell memebranes, [3H]flumazenil at a con...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/3/2015
Entry Details
US Patent

TargetGamma-aminobutyric acid receptor subunit alpha-5(Human)
Roche Palo Alto

US Patent
LigandChemical structure of BindingDB Monomer ID 133433BDBM133433(US8846719, 119)
Affinity DataKi:  0.700nM ΔG°:  -48.6kJ/molepH: 7.5 T: 2°CAssay Description:Radioligand binding assays were carried out in a volume of 200 mL (96-well plates) which contained 100 mL of cell memebranes, [3H]flumazenil at a con...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/3/2015
Entry Details
US Patent

TargetGamma-aminobutyric acid receptor subunit alpha-5(Human)
Roche Palo Alto

US Patent
LigandChemical structure of BindingDB Monomer ID 133507BDBM133507(US8846719, 196)
Affinity DataKi:  0.700nM ΔG°:  -48.6kJ/molepH: 7.5 T: 2°CAssay Description:Radioligand binding assays were carried out in a volume of 200 mL (96-well plates) which contained 100 mL of cell memebranes, [3H]flumazenil at a con...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/3/2015
Entry Details
US Patent

TargetGamma-aminobutyric acid receptor subunit alpha-5(Human)
Roche Palo Alto

US Patent
LigandChemical structure of BindingDB Monomer ID 133564BDBM133564(US8846719, 256)
Affinity DataKi:  0.800nM ΔG°:  -48.3kJ/molepH: 7.5 T: 2°CAssay Description:Radioligand binding assays were carried out in a volume of 200 mL (96-well plates) which contained 100 mL of cell memebranes, [3H]flumazenil at a con...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/3/2015
Entry Details
US Patent

TargetGamma-aminobutyric acid receptor subunit alpha-5(Human)
Roche Palo Alto

US Patent
LigandChemical structure of BindingDB Monomer ID 133561BDBM133561(US8846719, 253)
Affinity DataKi:  0.800nM ΔG°:  -48.3kJ/molepH: 7.5 T: 2°CAssay Description:Radioligand binding assays were carried out in a volume of 200 mL (96-well plates) which contained 100 mL of cell memebranes, [3H]flumazenil at a con...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/3/2015
Entry Details
US Patent

TargetGamma-aminobutyric acid receptor subunit alpha-5(Human)
Roche Palo Alto

US Patent
LigandChemical structure of BindingDB Monomer ID 133563BDBM133563(US8846719, 255)
Affinity DataKi:  0.800nM ΔG°:  -48.3kJ/molepH: 7.5 T: 2°CAssay Description:Radioligand binding assays were carried out in a volume of 200 mL (96-well plates) which contained 100 mL of cell memebranes, [3H]flumazenil at a con...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/3/2015
Entry Details
US Patent

TargetGamma-aminobutyric acid receptor subunit alpha-5(Human)
Roche Palo Alto

US Patent
LigandChemical structure of BindingDB Monomer ID 133435BDBM133435(US8846719, 121)
Affinity DataKi:  0.800nM ΔG°:  -48.3kJ/molepH: 7.5 T: 2°CAssay Description:Radioligand binding assays were carried out in a volume of 200 mL (96-well plates) which contained 100 mL of cell memebranes, [3H]flumazenil at a con...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/3/2015
Entry Details
US Patent

TargetGamma-aminobutyric acid receptor subunit alpha-5(Human)
Roche Palo Alto

US Patent
LigandChemical structure of BindingDB Monomer ID 133424BDBM133424(US8846719, 109)
Affinity DataKi:  0.800nM ΔG°:  -48.3kJ/molepH: 7.5 T: 2°CAssay Description:Radioligand binding assays were carried out in a volume of 200 mL (96-well plates) which contained 100 mL of cell memebranes, [3H]flumazenil at a con...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/3/2015
Entry Details
US Patent

TargetGamma-aminobutyric acid receptor subunit alpha-5(Human)
Roche Palo Alto

US Patent
LigandChemical structure of BindingDB Monomer ID 133559BDBM133559(US8846719, 251 | US11091471, Example RO-251 | US20...)
Affinity DataKi:  0.900nM ΔG°:  -48.0kJ/molepH: 7.5 T: 2°CAssay Description:Radioligand binding assays were carried out in a volume of 200 mL (96-well plates) which contained 100 mL of cell memebranes, [3H]flumazenil at a con...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/3/2015
Entry Details
US Patent

TargetGamma-aminobutyric acid receptor subunit alpha-5(Human)
Roche Palo Alto

US Patent
LigandChemical structure of BindingDB Monomer ID 133501BDBM133501(US8846719, 190)
Affinity DataKi:  1nM ΔG°:  -47.8kJ/molepH: 7.5 T: 2°CAssay Description:Radioligand binding assays were carried out in a volume of 200 mL (96-well plates) which contained 100 mL of cell memebranes, [3H]flumazenil at a con...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/3/2015
Entry Details
US Patent

TargetGamma-aminobutyric acid receptor subunit alpha-5(Human)
Roche Palo Alto

US Patent
LigandChemical structure of BindingDB Monomer ID 133560BDBM133560(US8846719, 252)
Affinity DataKi:  1nM ΔG°:  -47.8kJ/molepH: 7.5 T: 2°CAssay Description:Radioligand binding assays were carried out in a volume of 200 mL (96-well plates) which contained 100 mL of cell memebranes, [3H]flumazenil at a con...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/3/2015
Entry Details
US Patent

TargetGamma-aminobutyric acid receptor subunit alpha-5(Human)
Roche Palo Alto

US Patent
LigandChemical structure of BindingDB Monomer ID 133580BDBM133580(US8846719, 272 | US11091471, Example RO-272 | US20...)
Affinity DataKi:  1.10nM ΔG°:  -47.5kJ/molepH: 7.5 T: 2°CAssay Description:Radioligand binding assays were carried out in a volume of 200 mL (96-well plates) which contained 100 mL of cell memebranes, [3H]flumazenil at a con...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/3/2015
Entry Details
US Patent

TargetGamma-aminobutyric acid receptor subunit alpha-5(Human)
Roche Palo Alto

US Patent
LigandChemical structure of BindingDB Monomer ID 133554BDBM133554(US8846719, 246)
Affinity DataKi:  1.10nM ΔG°:  -47.5kJ/molepH: 7.5 T: 2°CAssay Description:Radioligand binding assays were carried out in a volume of 200 mL (96-well plates) which contained 100 mL of cell memebranes, [3H]flumazenil at a con...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/3/2015
Entry Details
US Patent

TargetGamma-aminobutyric acid receptor subunit alpha-5(Human)
Roche Palo Alto

US Patent
LigandChemical structure of BindingDB Monomer ID 133583BDBM133583(US8846719, 275)
Affinity DataKi:  1.10nM ΔG°:  -47.5kJ/molepH: 7.5 T: 2°CAssay Description:Radioligand binding assays were carried out in a volume of 200 mL (96-well plates) which contained 100 mL of cell memebranes, [3H]flumazenil at a con...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/3/2015
Entry Details
US Patent

TargetGamma-aminobutyric acid receptor subunit alpha-5(Human)
Roche Palo Alto

US Patent
LigandChemical structure of BindingDB Monomer ID 133545BDBM133545(US8846719, 237)
Affinity DataKi:  1.10nM ΔG°:  -47.5kJ/molepH: 7.5 T: 2°CAssay Description:Radioligand binding assays were carried out in a volume of 200 mL (96-well plates) which contained 100 mL of cell memebranes, [3H]flumazenil at a con...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/3/2015
Entry Details
US Patent

TargetGamma-aminobutyric acid receptor subunit alpha-5(Human)
Roche Palo Alto

US Patent
LigandChemical structure of BindingDB Monomer ID 133423BDBM133423(US8846719, 108)
Affinity DataKi:  1.10nM ΔG°:  -47.5kJ/molepH: 7.5 T: 2°CAssay Description:Radioligand binding assays were carried out in a volume of 200 mL (96-well plates) which contained 100 mL of cell memebranes, [3H]flumazenil at a con...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/3/2015
Entry Details
US Patent

TargetGamma-aminobutyric acid receptor subunit alpha-5(Human)
Roche Palo Alto

US Patent
LigandChemical structure of BindingDB Monomer ID 10657BDBM10657(US8846719, 280)
Affinity DataKi:  1.10nM ΔG°:  -47.5kJ/molepH: 7.5 T: 2°CAssay Description:Radioligand binding assays were carried out in a volume of 200 mL (96-well plates) which contained 100 mL of cell memebranes, [3H]flumazenil at a con...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/3/2015
Entry Details
US Patent

TargetGamma-aminobutyric acid receptor subunit alpha-5(Human)
Roche Palo Alto

US Patent
LigandChemical structure of BindingDB Monomer ID 10668BDBM10668(US8846719, 285)
Affinity DataKi:  1.10nM ΔG°:  -47.5kJ/molepH: 7.5 T: 2°CAssay Description:Radioligand binding assays were carried out in a volume of 200 mL (96-well plates) which contained 100 mL of cell memebranes, [3H]flumazenil at a con...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/3/2015
Entry Details
US Patent

TargetGamma-aminobutyric acid receptor subunit alpha-5(Human)
Roche Palo Alto

US Patent
LigandChemical structure of BindingDB Monomer ID 133434BDBM133434(US8846719, 120)
Affinity DataKi:  1.10nM ΔG°:  -47.5kJ/molepH: 7.5 T: 2°CAssay Description:Radioligand binding assays were carried out in a volume of 200 mL (96-well plates) which contained 100 mL of cell memebranes, [3H]flumazenil at a con...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/3/2015
Entry Details
US Patent

TargetGamma-aminobutyric acid receptor subunit alpha-5(Human)
Roche Palo Alto

US Patent
LigandChemical structure of BindingDB Monomer ID 133420BDBM133420(US8846719, 105)
Affinity DataKi:  1.20nM ΔG°:  -47.3kJ/molepH: 7.5 T: 2°CAssay Description:Radioligand binding assays were carried out in a volume of 200 mL (96-well plates) which contained 100 mL of cell memebranes, [3H]flumazenil at a con...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/3/2015
Entry Details
US Patent

TargetGamma-aminobutyric acid receptor subunit alpha-5(Human)
Roche Palo Alto

US Patent
LigandChemical structure of BindingDB Monomer ID 133534BDBM133534(US8846719, 230 | US8846719, 226)
Affinity DataKi:  1.20nM ΔG°:  -47.3kJ/molepH: 7.5 T: 2°CAssay Description:Radioligand binding assays were carried out in a volume of 200 mL (96-well plates) which contained 100 mL of cell memebranes, [3H]flumazenil at a con...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/3/2015
Entry Details
US Patent

TargetGamma-aminobutyric acid receptor subunit alpha-5(Human)
Roche Palo Alto

US Patent
LigandChemical structure of BindingDB Monomer ID 11456BDBM11456(US8846719, 293)
Affinity DataKi:  1.20nM ΔG°:  -47.3kJ/molepH: 7.5 T: 2°CAssay Description:Radioligand binding assays were carried out in a volume of 200 mL (96-well plates) which contained 100 mL of cell memebranes, [3H]flumazenil at a con...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/3/2015
Entry Details
US Patent

TargetGamma-aminobutyric acid receptor subunit alpha-5(Human)
Roche Palo Alto

US Patent
LigandChemical structure of BindingDB Monomer ID 10678BDBM10678(US8846719, 291)
Affinity DataKi:  1.20nM ΔG°:  -47.3kJ/molepH: 7.5 T: 2°CAssay Description:Radioligand binding assays were carried out in a volume of 200 mL (96-well plates) which contained 100 mL of cell memebranes, [3H]flumazenil at a con...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/3/2015
Entry Details
US Patent

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