Compile Data Set for Download or QSAR
Report error Found 62 Enz. Inhib. hit(s) with all data for entry = 6526
TargetPurine nucleoside phosphorylase(Human)
Industrial Research

US Patent
LigandChemical structure of BindingDB Monomer ID 50293091BDBM50293091(7-({[(1R,2S)-2,3-DIHYDROXY-1-(HYDROXYMETHYL)PROPYL...)
Affinity DataKd:  0.00860nMT: 2°CAssay Description:The inhibitor dissociation constants reported in Table 1 below are for phosphorolysis of inosine by PNP and were based on reaction rates measurements...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/16/2015
Entry Details
US Patent

TargetPurine nucleoside phosphorylase(Human)
Industrial Research

US Patent
LigandChemical structure of BindingDB Monomer ID 50293060BDBM50293060(7-{(1S)-1-[(1,3-Dihydroxypropan-2-yl)amino]-2-hydr...)
Affinity DataKd:  0.210nMT: 2°CAssay Description:The inhibitor dissociation constants reported in Table 1 below are for phosphorolysis of inosine by PNP and were based on reaction rates measurements...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/16/2015
Entry Details
US Patent

TargetPurine nucleoside phosphorylase(Human)
Industrial Research

US Patent
LigandChemical structure of BindingDB Monomer ID 50293063BDBM50293063(7-{[(1,3-Dihydroxypropan-2-yl)(2-hydroxyethyl)amin...)
Affinity DataKd:  0.469nMT: 2°CAssay Description:The inhibitor dissociation constants reported in Table 1 below are for phosphorolysis of inosine by PNP and were based on reaction rates measurements...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/16/2015
Entry Details
US Patent

TargetPurine nucleoside phosphorylase(Human)
Industrial Research

US Patent
LigandChemical structure of BindingDB Monomer ID 50293064BDBM50293064(Immucillins, 10 | CHEMBL523107 | 7-({[1,3-Dihydrox...)
Affinity DataKd:  0.620nMT: 2°CAssay Description:The inhibitor dissociation constants reported in Table 1 below are for phosphorolysis of inosine by PNP and were based on reaction rates measurements...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/16/2015
Entry Details
US Patent

TargetPurine nucleoside phosphorylase(Human)
Industrial Research

US Patent
LigandChemical structure of BindingDB Monomer ID 50293085BDBM50293085(7-({[(2R/S,3S/R)-3,4-Dihydroxy-2-(hydroxymethyl)bu...)
Affinity DataKd:  0.780nMT: 2°CAssay Description:The inhibitor dissociation constants reported in Table 1 below are for phosphorolysis of inosine by PNP and were based on reaction rates measurements...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/16/2015
Entry Details
US Patent

TargetPurine nucleoside phosphorylase(Human)
Industrial Research

US Patent
LigandChemical structure of BindingDB Monomer ID 50293067BDBM50293067(7-({[(2S,3R)-1,3,4-Trihydroxybutan-2-yl]amino}meth...)
Affinity DataKd:  1nMT: 2°CAssay Description:The inhibitor dissociation constants reported in Table 1 below are for phosphorolysis of inosine by PNP and were based on reaction rates measurements...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/16/2015
Entry Details
US Patent

TargetPurine nucleoside phosphorylase(Human)
Industrial Research

US Patent
LigandChemical structure of BindingDB Monomer ID 50293068BDBM50293068(7-{[(2-Hydroxyethyl)amino]methyl}-3,5-dihydro-4H-p...)
Affinity DataKd:  1.10nMT: 2°CAssay Description:The inhibitor dissociation constants reported in Table 1 below are for phosphorolysis of inosine by PNP and were based on reaction rates measurements...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/16/2015
Entry Details
US Patent

TargetPurine nucleoside phosphorylase(Human)
Industrial Research

US Patent
LigandChemical structure of BindingDB Monomer ID 136302BDBM136302(US8853224, 12 | US9290501, MT-TrisMe-ImmH)
Affinity DataKd:  3nMT: 2°CAssay Description:The inhibitor dissociation constants reported in Table 1 below are for phosphorolysis of inosine by PNP and were based on reaction rates measurements...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/16/2015
Entry Details
US Patent

TargetPurine nucleoside phosphorylase(Human)
Industrial Research

US Patent
LigandChemical structure of BindingDB Monomer ID 50293070BDBM50293070(7-({[3-Hydroxy-2-(hydroxymethyl)propyl](methyl)ami...)
Affinity DataKd:  3.70nMT: 2°CAssay Description:The inhibitor dissociation constants reported in Table 1 below are for phosphorolysis of inosine by PNP and were based on reaction rates measurements...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/16/2015
Entry Details
US Patent

TargetPurine nucleoside phosphorylase(Human)
Industrial Research

US Patent
LigandChemical structure of BindingDB Monomer ID 50293071BDBM50293071(7-({[(2S)-2,3-Dihydroxypropyl]amino}methyl)-3,5-di...)
Affinity DataKd:  4.20nMT: 2°CAssay Description:The inhibitor dissociation constants reported in Table 1 below are for phosphorolysis of inosine by PNP and were based on reaction rates measurements...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/16/2015
Entry Details
US Patent

TargetPurine nucleoside phosphorylase(Human)
Industrial Research

US Patent
LigandChemical structure of BindingDB Monomer ID 50293072BDBM50293072(7-({[(2R,3R)-1,3,4-Trihydroxybutan-2-yl]amino}meth...)
Affinity DataKd:  4.30nMT: 2°CAssay Description:The inhibitor dissociation constants reported in Table 1 below are for phosphorolysis of inosine by PNP and were based on reaction rates measurements...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/16/2015
Entry Details
US Patent

TargetPurine nucleoside phosphorylase(Human)
Industrial Research

US Patent
LigandChemical structure of BindingDB Monomer ID 50293073BDBM50293073(7-({[(2S,3S)-1,3,4-Trihydroxybutan-2-yl]amino}meth...)
Affinity DataKd:  5.20nMT: 2°CAssay Description:The inhibitor dissociation constants reported in Table 1 below are for phosphorolysis of inosine by PNP and were based on reaction rates measurements...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/16/2015
Entry Details
US Patent

TargetPurine nucleoside phosphorylase(Human)
Industrial Research

US Patent
LigandChemical structure of BindingDB Monomer ID 136310BDBM136310(US8853224, 28)
Affinity DataKd:  5.60nMT: 2°CAssay Description:The inhibitor dissociation constants reported in Table 1 below are for phosphorolysis of inosine by PNP and were based on reaction rates measurements...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/16/2015
Entry Details
US Patent

TargetPurine nucleoside phosphorylase(Human)
Industrial Research

US Patent
LigandChemical structure of BindingDB Monomer ID 50293075BDBM50293075(7-({[3-Hydroxy-2-(hydroxymethyl)propyl]amino}methy...)
Affinity DataKd:  14.1nMT: 2°CAssay Description:The inhibitor dissociation constants reported in Table 1 below are for phosphorolysis of inosine by PNP and were based on reaction rates measurements...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/16/2015
Entry Details
US Patent

TargetPurine nucleoside phosphorylase(Human)
Industrial Research

US Patent
LigandChemical structure of BindingDB Monomer ID 50293076BDBM50293076(7-({[(2R)-2,3-Dihydroxypropyl]amino}methyl)-3,5-di...)
Affinity DataKd:  14.9nMT: 2°CAssay Description:The inhibitor dissociation constants reported in Table 1 below are for phosphorolysis of inosine by PNP and were based on reaction rates measurements...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/16/2015
Entry Details
US Patent

TargetPurine nucleoside phosphorylase(Human)
Industrial Research

US Patent
LigandChemical structure of BindingDB Monomer ID 136306BDBM136306(US8853224, 24)
Affinity DataKd:  15nMT: 2°CAssay Description:The inhibitor dissociation constants reported in Table 1 below are for phosphorolysis of inosine by PNP and were based on reaction rates measurements...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/16/2015
Entry Details
US Patent

TargetPurine nucleoside phosphorylase(malaria parasite P. falciparum)
Industrial Research

US Patent
LigandChemical structure of BindingDB Monomer ID 136306BDBM136306(US8853224, 24)
Affinity DataKd:  19nMT: 2°CAssay Description:The inhibitor dissociation constants reported in Table 1 below are for phosphorolysis of inosine by PNP and were based on reaction rates measurements...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/16/2015
Entry Details
US Patent

TargetPurine nucleoside phosphorylase(Human)
Industrial Research

US Patent
LigandChemical structure of BindingDB Monomer ID 136312BDBM136312(US8853224, 29)
Affinity DataKd:  22nMT: 2°CAssay Description:The inhibitor dissociation constants reported in Table 1 below are for phosphorolysis of inosine by PNP and were based on reaction rates measurements...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/16/2015
Entry Details
US Patent

TargetPurine nucleoside phosphorylase(Human)
Industrial Research

US Patent
LigandChemical structure of BindingDB Monomer ID 50293077BDBM50293077(7-{[(4-Hydroxybutyl)amino]methyl}-3,5-dihydro-4H-p...)
Affinity DataKd:  25nMT: 2°CAssay Description:The inhibitor dissociation constants reported in Table 1 below are for phosphorolysis of inosine by PNP and were based on reaction rates measurements...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/16/2015
Entry Details
US Patent

TargetPurine nucleoside phosphorylase(Human)
Industrial Research

US Patent
LigandChemical structure of BindingDB Monomer ID 50293078BDBM50293078(7-({[(2S,3R)-2,3,4-Trihydroxybutyl]amino}methyl)-3...)
Affinity DataKd:  31nMT: 2°CAssay Description:The inhibitor dissociation constants reported in Table 1 below are for phosphorolysis of inosine by PNP and were based on reaction rates measurements...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/16/2015
Entry Details
US Patent

TargetPurine nucleoside phosphorylase(Human)
Industrial Research

US Patent
LigandChemical structure of BindingDB Monomer ID 136313BDBM136313(US8853224, 19)
Affinity DataKd:  51nMT: 2°CAssay Description:The inhibitor dissociation constants reported in Table 1 below are for phosphorolysis of inosine by PNP and were based on reaction rates measurements...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/16/2015
Entry Details
US Patent

TargetPurine nucleoside phosphorylase(malaria parasite P. falciparum)
Industrial Research

US Patent
LigandChemical structure of BindingDB Monomer ID 50293091BDBM50293091(7-({[(1R,2S)-2,3-DIHYDROXY-1-(HYDROXYMETHYL)PROPYL...)
Affinity DataKd:  55nMT: 2°CAssay Description:The inhibitor dissociation constants reported in Table 1 below are for phosphorolysis of inosine by PNP and were based on reaction rates measurements...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/16/2015
Entry Details
US Patent

TargetPurine nucleoside phosphorylase(Human)
Industrial Research

US Patent
LigandChemical structure of BindingDB Monomer ID 136308BDBM136308(US8853224, 26)
Affinity DataKd:  71nMT: 2°CAssay Description:The inhibitor dissociation constants reported in Table 1 below are for phosphorolysis of inosine by PNP and were based on reaction rates measurements...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/16/2015
Entry Details
US Patent

TargetPurine nucleoside phosphorylase(Human)
Industrial Research

US Patent
LigandChemical structure of BindingDB Monomer ID 136307BDBM136307(US8853224, 25)
Affinity DataKd:  74nMT: 2°CAssay Description:The inhibitor dissociation constants reported in Table 1 below are for phosphorolysis of inosine by PNP and were based on reaction rates measurements...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/16/2015
Entry Details
US Patent

TargetPurine nucleoside phosphorylase(Human)
Industrial Research

US Patent
LigandChemical structure of BindingDB Monomer ID 136304BDBM136304(US8853224, 20.5)
Affinity DataKd:  84nMT: 2°CAssay Description:The inhibitor dissociation constants reported in Table 1 below are for phosphorolysis of inosine by PNP and were based on reaction rates measurements...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/16/2015
Entry Details
US Patent

TargetPurine nucleoside phosphorylase(Human)
Industrial Research

US Patent
LigandChemical structure of BindingDB Monomer ID 50293081BDBM50293081(7-({[(2R)-2,3-Dihydroxypropyl](2-hydroxyethyl)amin...)
Affinity DataKd:  96nMT: 2°CAssay Description:The inhibitor dissociation constants reported in Table 1 below are for phosphorolysis of inosine by PNP and were based on reaction rates measurements...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/16/2015
Entry Details
US Patent

TargetPurine nucleoside phosphorylase(Human)
Industrial Research

US Patent
LigandChemical structure of BindingDB Monomer ID 136309BDBM136309(US8853224, 27)
Affinity DataKd:  142nMT: 2°CAssay Description:The inhibitor dissociation constants reported in Table 1 below are for phosphorolysis of inosine by PNP and were based on reaction rates measurements...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/16/2015
Entry Details
US Patent

TargetPurine nucleoside phosphorylase(Human)
Industrial Research

US Patent
LigandChemical structure of BindingDB Monomer ID 136311BDBM136311(US8853224, 23)
Affinity DataKd:  159nMT: 2°CAssay Description:The inhibitor dissociation constants reported in Table 1 below are for phosphorolysis of inosine by PNP and were based on reaction rates measurements...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/16/2015
Entry Details
US Patent

TargetPurine nucleoside phosphorylase(malaria parasite P. falciparum)
Industrial Research

US Patent
LigandChemical structure of BindingDB Monomer ID 50293064BDBM50293064(Immucillins, 10 | CHEMBL523107 | 7-({[1,3-Dihydrox...)
Affinity DataKd:  163nMT: 2°CAssay Description:The inhibitor dissociation constants reported in Table 1 below are for phosphorolysis of inosine by PNP and were based on reaction rates measurements...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/16/2015
Entry Details
US Patent

TargetPurine nucleoside phosphorylase(Human)
Industrial Research

US Patent
LigandChemical structure of BindingDB Monomer ID 50293079BDBM50293079(7-({[(2S)-2,3-Dihydroxypropyl](2-hydroxyethyl)amin...)
Affinity DataKd:  165nMT: 2°CAssay Description:The inhibitor dissociation constants reported in Table 1 below are for phosphorolysis of inosine by PNP and were based on reaction rates measurements...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/16/2015
Entry Details
US Patent

TargetPurine nucleoside phosphorylase(malaria parasite P. falciparum)
Industrial Research

US Patent
LigandChemical structure of BindingDB Monomer ID 50293067BDBM50293067(7-({[(2S,3R)-1,3,4-Trihydroxybutan-2-yl]amino}meth...)
Affinity DataKd:  210nMT: 2°CAssay Description:The inhibitor dissociation constants reported in Table 1 below are for phosphorolysis of inosine by PNP and were based on reaction rates measurements...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/16/2015
Entry Details
US Patent

TargetPurine nucleoside phosphorylase(malaria parasite P. falciparum)
Industrial Research

US Patent
LigandChemical structure of BindingDB Monomer ID 50293075BDBM50293075(7-({[3-Hydroxy-2-(hydroxymethyl)propyl]amino}methy...)
Affinity DataKd:  210nMT: 2°CAssay Description:The inhibitor dissociation constants reported in Table 1 below are for phosphorolysis of inosine by PNP and were based on reaction rates measurements...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/16/2015
Entry Details
US Patent

TargetPurine nucleoside phosphorylase(Human)
Industrial Research

US Patent
LigandChemical structure of BindingDB Monomer ID 50293083BDBM50293083(7-({[(2R/S)-2,4-Dihydroxybutyl](methyl)amino}methy...)
Affinity DataKd:  227nMT: 2°CAssay Description:The inhibitor dissociation constants reported in Table 1 below are for phosphorolysis of inosine by PNP and were based on reaction rates measurements...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/16/2015
Entry Details
US Patent

TargetPurine nucleoside phosphorylase(malaria parasite P. falciparum)
Industrial Research

US Patent
LigandChemical structure of BindingDB Monomer ID 50293071BDBM50293071(7-({[(2S)-2,3-Dihydroxypropyl]amino}methyl)-3,5-di...)
Affinity DataKd:  260nMT: 2°CAssay Description:The inhibitor dissociation constants reported in Table 1 below are for phosphorolysis of inosine by PNP and were based on reaction rates measurements...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/16/2015
Entry Details
US Patent

TargetPurine nucleoside phosphorylase(malaria parasite P. falciparum)
Industrial Research

US Patent
LigandChemical structure of BindingDB Monomer ID 50293060BDBM50293060(7-{(1S)-1-[(1,3-Dihydroxypropan-2-yl)amino]-2-hydr...)
Affinity DataKd:  297nMT: 2°CAssay Description:The inhibitor dissociation constants reported in Table 1 below are for phosphorolysis of inosine by PNP and were based on reaction rates measurements...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/16/2015
Entry Details
US Patent

TargetPurine nucleoside phosphorylase(Human)
Industrial Research

US Patent
LigandChemical structure of BindingDB Monomer ID 136303BDBM136303(US8853224, 3.4)
Affinity DataKd:  300nMT: 2°CAssay Description:The inhibitor dissociation constants reported in Table 1 below are for phosphorolysis of inosine by PNP and were based on reaction rates measurements...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/16/2015
Entry Details
US Patent

TargetPurine nucleoside phosphorylase(malaria parasite P. falciparum)
Industrial Research

US Patent
LigandChemical structure of BindingDB Monomer ID 50293068BDBM50293068(7-{[(2-Hydroxyethyl)amino]methyl}-3,5-dihydro-4H-p...)
Affinity DataKd:  430nMT: 2°CAssay Description:The inhibitor dissociation constants reported in Table 1 below are for phosphorolysis of inosine by PNP and were based on reaction rates measurements...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/16/2015
Entry Details
US Patent

TargetPurine nucleoside phosphorylase(malaria parasite P. falciparum)
Industrial Research

US Patent
LigandChemical structure of BindingDB Monomer ID 50293079BDBM50293079(7-({[(2S)-2,3-Dihydroxypropyl](2-hydroxyethyl)amin...)
Affinity DataKd:  550nMT: 2°CAssay Description:The inhibitor dissociation constants reported in Table 1 below are for phosphorolysis of inosine by PNP and were based on reaction rates measurements...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/16/2015
Entry Details
US Patent

TargetPurine nucleoside phosphorylase(malaria parasite P. falciparum)
Industrial Research

US Patent
LigandChemical structure of BindingDB Monomer ID 50293077BDBM50293077(7-{[(4-Hydroxybutyl)amino]methyl}-3,5-dihydro-4H-p...)
Affinity DataKd:  770nMT: 2°CAssay Description:The inhibitor dissociation constants reported in Table 1 below are for phosphorolysis of inosine by PNP and were based on reaction rates measurements...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/16/2015
Entry Details
US Patent

TargetPurine nucleoside phosphorylase(malaria parasite P. falciparum)
Industrial Research

US Patent
LigandChemical structure of BindingDB Monomer ID 50293083BDBM50293083(7-({[(2R/S)-2,4-Dihydroxybutyl](methyl)amino}methy...)
Affinity DataKd:  770nMT: 2°CAssay Description:The inhibitor dissociation constants reported in Table 1 below are for phosphorolysis of inosine by PNP and were based on reaction rates measurements...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/16/2015
Entry Details
US Patent

TargetPurine nucleoside phosphorylase(malaria parasite P. falciparum)
Industrial Research

US Patent
LigandChemical structure of BindingDB Monomer ID 50293072BDBM50293072(7-({[(2R,3R)-1,3,4-Trihydroxybutan-2-yl]amino}meth...)
Affinity DataKd:  770nMT: 2°CAssay Description:The inhibitor dissociation constants reported in Table 1 below are for phosphorolysis of inosine by PNP and were based on reaction rates measurements...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/16/2015
Entry Details
US Patent

TargetPurine nucleoside phosphorylase(Human)
Industrial Research

US Patent
LigandChemical structure of BindingDB Monomer ID 136314BDBM136314(US8853224, 20.8)
Affinity DataKd:  789nMT: 2°CAssay Description:The inhibitor dissociation constants reported in Table 1 below are for phosphorolysis of inosine by PNP and were based on reaction rates measurements...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/16/2015
Entry Details
US Patent

TargetPurine nucleoside phosphorylase(Human)
Industrial Research

US Patent
LigandChemical structure of BindingDB Monomer ID 136305BDBM136305(US8853224, 22)
Affinity DataKd:  900nMT: 2°CAssay Description:The inhibitor dissociation constants reported in Table 1 below are for phosphorolysis of inosine by PNP and were based on reaction rates measurements...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/16/2015
Entry Details
US Patent

TargetPurine nucleoside phosphorylase(malaria parasite P. falciparum)
Industrial Research

US Patent
LigandChemical structure of BindingDB Monomer ID 50293063BDBM50293063(7-{[(1,3-Dihydroxypropan-2-yl)(2-hydroxyethyl)amin...)
Affinity DataKd:  1.00E+3nMT: 2°CAssay Description:The inhibitor dissociation constants reported in Table 1 below are for phosphorolysis of inosine by PNP and were based on reaction rates measurements...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/16/2015
Entry Details
US Patent

TargetPurine nucleoside phosphorylase(malaria parasite P. falciparum)
Industrial Research

US Patent
LigandChemical structure of BindingDB Monomer ID 136312BDBM136312(US8853224, 29)
Affinity DataKd:  1.10E+3nMT: 2°CAssay Description:The inhibitor dissociation constants reported in Table 1 below are for phosphorolysis of inosine by PNP and were based on reaction rates measurements...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/16/2015
Entry Details
US Patent

TargetPurine nucleoside phosphorylase(malaria parasite P. falciparum)
Industrial Research

US Patent
LigandChemical structure of BindingDB Monomer ID 50293081BDBM50293081(7-({[(2R)-2,3-Dihydroxypropyl](2-hydroxyethyl)amin...)
Affinity DataKd:  1.38E+3nMT: 2°CAssay Description:The inhibitor dissociation constants reported in Table 1 below are for phosphorolysis of inosine by PNP and were based on reaction rates measurements...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/16/2015
Entry Details
US Patent

TargetPurine nucleoside phosphorylase(malaria parasite P. falciparum)
Industrial Research

US Patent
LigandChemical structure of BindingDB Monomer ID 50293076BDBM50293076(7-({[(2R)-2,3-Dihydroxypropyl]amino}methyl)-3,5-di...)
Affinity DataKd:  1.80E+3nMT: 2°CAssay Description:The inhibitor dissociation constants reported in Table 1 below are for phosphorolysis of inosine by PNP and were based on reaction rates measurements...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/16/2015
Entry Details
US Patent

TargetPurine nucleoside phosphorylase(malaria parasite P. falciparum)
Industrial Research

US Patent
LigandChemical structure of BindingDB Monomer ID 50293070BDBM50293070(7-({[3-Hydroxy-2-(hydroxymethyl)propyl](methyl)ami...)
Affinity DataKd:  2.00E+3nMT: 2°CAssay Description:The inhibitor dissociation constants reported in Table 1 below are for phosphorolysis of inosine by PNP and were based on reaction rates measurements...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/16/2015
Entry Details
US Patent

TargetPurine nucleoside phosphorylase(malaria parasite P. falciparum)
Industrial Research

US Patent
LigandChemical structure of BindingDB Monomer ID 136303BDBM136303(US8853224, 3.4)
Affinity DataKd:  2.00E+3nMT: 2°CAssay Description:The inhibitor dissociation constants reported in Table 1 below are for phosphorolysis of inosine by PNP and were based on reaction rates measurements...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/16/2015
Entry Details
US Patent

TargetPurine nucleoside phosphorylase(malaria parasite P. falciparum)
Industrial Research

US Patent
LigandChemical structure of BindingDB Monomer ID 50293085BDBM50293085(7-({[(2R/S,3S/R)-3,4-Dihydroxy-2-(hydroxymethyl)bu...)
Affinity DataKd:  2.20E+3nMT: 2°CAssay Description:The inhibitor dissociation constants reported in Table 1 below are for phosphorolysis of inosine by PNP and were based on reaction rates measurements...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/16/2015
Entry Details
US Patent

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