Compile Data Set for Download or QSAR
Report error Found 5 Enz. Inhib. hit(s) with all data for entry = 6535
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A(Human)
Basilea Pharmaceutica

US Patent
LigandPNGBDBM136701(US8865662, 4)
Affinity DataIC50: 30nMpH: 7.2Assay Description:PDE4 specifically hydrolyzes cAMP and releases the product AMP. The potency of PDE inhibition by said agents is determined in an in vitro enzymatic a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/6/2015
Entry Details
US Patent

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A(Human)
Basilea Pharmaceutica

US Patent
LigandPNGBDBM136700(US8865662, 5)
Affinity DataIC50: 200nMpH: 7.2Assay Description:PDE4 specifically hydrolyzes cAMP and releases the product AMP. The potency of PDE inhibition by said agents is determined in an in vitro enzymatic a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/6/2015
Entry Details
US Patent

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A(Human)
Basilea Pharmaceutica

US Patent
LigandPNGBDBM136697(US8865662, 1)
Affinity DataIC50: 230nMpH: 7.2Assay Description:PDE4 specifically hydrolyzes cAMP and releases the product AMP. The potency of PDE inhibition by said agents is determined in an in vitro enzymatic a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/6/2015
Entry Details
US Patent

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A(Human)
Basilea Pharmaceutica

US Patent
LigandPNGBDBM136699(US8865662, 3 | US9738676, WS2011/018510, Expl. 2)
Affinity DataIC50: 630nMpH: 7.2Assay Description:PDE4 specifically hydrolyzes cAMP and releases the product AMP. The potency of PDE inhibition by said agents is determined in an in vitro enzymatic a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/6/2015
Entry Details
US Patent

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A(Human)
Basilea Pharmaceutica

US Patent
LigandPNGBDBM136698(US8865662, 2)
Affinity DataIC50: 880nMpH: 7.2Assay Description:PDE4 specifically hydrolyzes cAMP and releases the product AMP. The potency of PDE inhibition by said agents is determined in an in vitro enzymatic a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/6/2015
Entry Details
US Patent