Compile Data Set for Download or QSAR
Report error Found 8 Enz. Inhib. hit(s) with all data for entry = 6534
TargetTyrosyl-DNA phosphodiesterase 1(Human)
The United States of America, As Represented By The Secretary, Dept. of Health and Human Services

US Patent
LigandChemical structure of BindingDB Monomer ID 136689BDBM136689(US8865686, Table 1, Compound 2)
Affinity DataIC50: 9.00E+3nMpH: 8.0 T: 2°CAssay Description:Assay: Unless indicated otherwise, Tdp1 assays were performed in 20 ul mixtures containing 50 mM Tris-HCl, pH 8.0, 80 mM KCl, 2 mM EDTA, 1 mM dithiot...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/6/2015
Entry Details
US Patent

TargetTyrosyl-DNA phosphodiesterase 1(Human)
The United States of America, As Represented By The Secretary, Dept. of Health and Human Services

US Patent
LigandChemical structure of BindingDB Monomer ID 136691BDBM136691(US8865686, Table 1, Compound 3)
Affinity DataIC50: 2.90E+4nMpH: 8.0 T: 2°CAssay Description:Assay: Unless indicated otherwise, Tdp1 assays were performed in 20 ul mixtures containing 50 mM Tris-HCl, pH 8.0, 80 mM KCl, 2 mM EDTA, 1 mM dithiot...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/6/2015
Entry Details
US Patent

TargetTyrosyl-DNA phosphodiesterase 1(Human)
The United States of America, As Represented By The Secretary, Dept. of Health and Human Services

US Patent
LigandChemical structure of BindingDB Monomer ID 136692BDBM136692(US8865686, Table 1, Compound 4)
Affinity DataIC50: 4.90E+4nMpH: 8.0 T: 2°CAssay Description:Assay: Unless indicated otherwise, Tdp1 assays were performed in 20 ul mixtures containing 50 mM Tris-HCl, pH 8.0, 80 mM KCl, 2 mM EDTA, 1 mM dithiot...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/6/2015
Entry Details
US Patent

TargetTyrosyl-DNA phosphodiesterase 1(Human)
The United States of America, As Represented By The Secretary, Dept. of Health and Human Services

US Patent
LigandChemical structure of BindingDB Monomer ID 136693BDBM136693(US8865686, Table 1, Compound 5)
Affinity DataIC50: 8.40E+4nMpH: 8.0 T: 2°CAssay Description:Assay: Unless indicated otherwise, Tdp1 assays were performed in 20 ul mixtures containing 50 mM Tris-HCl, pH 8.0, 80 mM KCl, 2 mM EDTA, 1 mM dithiot...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/6/2015
Entry Details
US Patent

TargetTyrosyl-DNA phosphodiesterase 1(Human)
The United States of America, As Represented By The Secretary, Dept. of Health and Human Services

US Patent
LigandChemical structure of BindingDB Monomer ID 136694BDBM136694(US8865686, Table 1, Compound 6)
Affinity DataIC50: 1.06E+5nMpH: 8.0 T: 2°CAssay Description:Assay: Unless indicated otherwise, Tdp1 assays were performed in 20 ul mixtures containing 50 mM Tris-HCl, pH 8.0, 80 mM KCl, 2 mM EDTA, 1 mM dithiot...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/6/2015
Entry Details
US Patent

TargetTyrosyl-DNA phosphodiesterase 1(Human)
The United States of America, As Represented By The Secretary, Dept. of Health and Human Services

US Patent
LigandChemical structure of BindingDB Monomer ID 136695BDBM136695(US8865686, Table 1, Compound 7)
Affinity DataIC50: 1.22E+5nMpH: 8.0 T: 2°CAssay Description:Assay: Unless indicated otherwise, Tdp1 assays were performed in 20 ul mixtures containing 50 mM Tris-HCl, pH 8.0, 80 mM KCl, 2 mM EDTA, 1 mM dithiot...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/6/2015
Entry Details
US Patent

TargetTyrosyl-DNA phosphodiesterase 1(Human)
The United States of America, As Represented By The Secretary, Dept. of Health and Human Services

US Patent
LigandChemical structure of BindingDB Monomer ID 136696BDBM136696(US8865686, Table 1, Compound 8)
Affinity DataIC50: 1.41E+5nMpH: 8.0 T: 2°CAssay Description:Assay: Unless indicated otherwise, Tdp1 assays were performed in 20 ul mixtures containing 50 mM Tris-HCl, pH 8.0, 80 mM KCl, 2 mM EDTA, 1 mM dithiot...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/6/2015
Entry Details
US Patent

TargetTyrosyl-DNA phosphodiesterase 1(Human)
The United States of America, As Represented By The Secretary, Dept. of Health and Human Services

US Patent
LigandChemical structure of BindingDB Monomer ID 136690BDBM136690(US8865686, Table 1, Compound 1)
Affinity DataIC50: 7.85E+5nMpH: 8.0 T: 2°CAssay Description:Assay: Unless indicated otherwise, Tdp1 assays were performed in 20 ul mixtures containing 50 mM Tris-HCl, pH 8.0, 80 mM KCl, 2 mM EDTA, 1 mM dithiot...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/6/2015
Entry Details
US Patent