Compile Data Set for Download or QSAR
Report error Found 7 Enz. Inhib. hit(s) with all data for entry = 6549
TargetNeprilysin(Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 138390BDBM138390(US8877786, Example 3-1)
Affinity DataIC50: 0.0900nMpH: 7.4 T: 2°CAssay Description:The in vitro inhibition of recombinant human neutral endopeptidase (NEP, EC 3.424.11) can be determined as follows:Recombinant human neutral endopept...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2015
Entry Details
US Patent

TargetNeprilysin(Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 138395BDBM138395(US8877786, Example 3-12)
Affinity DataIC50: 0.200nMpH: 7.4 T: 2°CAssay Description:The in vitro inhibition of recombinant human neutral endopeptidase (NEP, EC 3.424.11) can be determined as follows:Recombinant human neutral endopept...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2015
Entry Details
US Patent

TargetNeprilysin(Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 138396BDBM138396(US8877786, Example 3-13)
Affinity DataIC50: 0.200nMpH: 7.4 T: 2°CAssay Description:The in vitro inhibition of recombinant human neutral endopeptidase (NEP, EC 3.424.11) can be determined as follows:Recombinant human neutral endopept...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2015
Entry Details
US Patent

TargetNeprilysin(Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 138391BDBM138391(US8877786, Example 3-2)
Affinity DataIC50: 0.300nMpH: 7.4 T: 2°CAssay Description:The in vitro inhibition of recombinant human neutral endopeptidase (NEP, EC 3.424.11) can be determined as follows:Recombinant human neutral endopept...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2015
Entry Details
US Patent

TargetNeprilysin(Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 138393BDBM138393(US8877786, Example 3-7 | US8993631, 32-4)
Affinity DataIC50: 2.40nMpH: 7.4 T: 2°CAssay Description:The in vitro inhibition of recombinant human neutral endopeptidase (NEP, EC 3.424.11) can be determined as follows:Recombinant human neutral endopept...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2015
Entry Details
US Patent

TargetNeprilysin(Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 138392BDBM138392(US8877786, Example 3-4)
Affinity DataIC50: 11nMpH: 7.4 T: 2°CAssay Description:The in vitro inhibition of recombinant human neutral endopeptidase (NEP, EC 3.424.11) can be determined as follows:Recombinant human neutral endopept...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2015
Entry Details
US Patent

TargetNeprilysin(Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 138394BDBM138394(US8877786, Example 3-10)
Affinity DataIC50: 91nMpH: 7.4 T: 2°CAssay Description:The in vitro inhibition of recombinant human neutral endopeptidase (NEP, EC 3.424.11) can be determined as follows:Recombinant human neutral endopept...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2015
Entry Details
US Patent