Compile Data Set for Download or QSAR
Report error Found 39 Enz. Inhib. hit(s) with all data for entry = 6581
TargetProtein O-GlcNAcase(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 139926BDBM139926(US8901087, 2)
Affinity DataKi:  0.0500nM ΔG°:  -58.8kJ/molepH: 7.0 T: 2°CAssay Description:Enzymatic reactions are carried out in a reaction containing 50 mM NaH2PO4, 100 mM NaCl and 0.1% BSA (pH 7.0) using 2 mM 4-Methylumbelliferyl N-acety...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/4/2015
Entry Details
US Patent

TargetProtein O-GlcNAcase(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 139933BDBM139933(US8901087, 27)
Affinity DataKi:  0.120nM ΔG°:  -56.6kJ/molepH: 7.0 T: 2°CAssay Description:Enzymatic reactions are carried out in a reaction containing 50 mM NaH2PO4, 100 mM NaCl and 0.1% BSA (pH 7.0) using 2 mM 4-Methylumbelliferyl N-acety...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/4/2015
Entry Details
US Patent

TargetProtein O-GlcNAcase(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 139959BDBM139959(US8901087, 191)
Affinity DataKi:  0.140nM ΔG°:  -56.2kJ/molepH: 7.0 T: 2°CAssay Description:Enzymatic reactions are carried out in a reaction containing 50 mM NaH2PO4, 100 mM NaCl and 0.1% BSA (pH 7.0) using 2 mM 4-Methylumbelliferyl N-acety...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/4/2015
Entry Details
US Patent

TargetProtein O-GlcNAcase(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 139951BDBM139951(US8901087, 95)
Affinity DataKi:  0.160nM ΔG°:  -55.9kJ/molepH: 7.0 T: 2°CAssay Description:Enzymatic reactions are carried out in a reaction containing 50 mM NaH2PO4, 100 mM NaCl and 0.1% BSA (pH 7.0) using 2 mM 4-Methylumbelliferyl N-acety...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/4/2015
Entry Details
US Patent

TargetProtein O-GlcNAcase(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 139952BDBM139952(US8901087, 97)
Affinity DataKi:  0.170nM ΔG°:  -55.8kJ/molepH: 7.0 T: 2°CAssay Description:Enzymatic reactions are carried out in a reaction containing 50 mM NaH2PO4, 100 mM NaCl and 0.1% BSA (pH 7.0) using 2 mM 4-Methylumbelliferyl N-acety...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/4/2015
Entry Details
US Patent

TargetProtein O-GlcNAcase(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 139925BDBM139925(US8901087, 1)
Affinity DataKi:  0.170nM ΔG°:  -55.8kJ/molepH: 7.0 T: 2°CAssay Description:Enzymatic reactions are carried out in a reaction containing 50 mM NaH2PO4, 100 mM NaCl and 0.1% BSA (pH 7.0) using 2 mM 4-Methylumbelliferyl N-acety...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/4/2015
Entry Details
US Patent

TargetProtein O-GlcNAcase(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 139946BDBM139946(US8901087, 76)
Affinity DataKi:  0.180nM ΔG°:  -55.6kJ/molepH: 7.0 T: 2°CAssay Description:Enzymatic reactions are carried out in a reaction containing 50 mM NaH2PO4, 100 mM NaCl and 0.1% BSA (pH 7.0) using 2 mM 4-Methylumbelliferyl N-acety...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/4/2015
Entry Details
US Patent

TargetProtein O-GlcNAcase(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 46008BDBM46008(US8901087, 96)
Affinity DataKi:  0.190nM ΔG°:  -55.5kJ/molepH: 7.0 T: 2°CAssay Description:Enzymatic reactions are carried out in a reaction containing 50 mM NaH2PO4, 100 mM NaCl and 0.1% BSA (pH 7.0) using 2 mM 4-Methylumbelliferyl N-acety...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/4/2015
Entry Details
US Patent

TargetProtein O-GlcNAcase(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 139941BDBM139941(US8901087, 63)
Affinity DataKi:  0.220nM ΔG°:  -55.1kJ/molepH: 7.0 T: 2°CAssay Description:Enzymatic reactions are carried out in a reaction containing 50 mM NaH2PO4, 100 mM NaCl and 0.1% BSA (pH 7.0) using 2 mM 4-Methylumbelliferyl N-acety...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/4/2015
Entry Details
US Patent

TargetProtein O-GlcNAcase(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 139930BDBM139930(US8901087, 11)
Affinity DataKi:  0.300nM ΔG°:  -54.4kJ/molepH: 7.0 T: 2°CAssay Description:Enzymatic reactions are carried out in a reaction containing 50 mM NaH2PO4, 100 mM NaCl and 0.1% BSA (pH 7.0) using 2 mM 4-Methylumbelliferyl N-acety...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/4/2015
Entry Details
US Patent

TargetProtein O-GlcNAcase(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 139939BDBM139939(US8901087, 57)
Affinity DataKi:  0.330nM ΔG°:  -54.1kJ/molepH: 7.0 T: 2°CAssay Description:Enzymatic reactions are carried out in a reaction containing 50 mM NaH2PO4, 100 mM NaCl and 0.1% BSA (pH 7.0) using 2 mM 4-Methylumbelliferyl N-acety...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/4/2015
Entry Details
US Patent

TargetProtein O-GlcNAcase(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 139931BDBM139931(US8901087, 13)
Affinity DataKi:  0.400nM ΔG°:  -53.6kJ/molepH: 7.0 T: 2°CAssay Description:Enzymatic reactions are carried out in a reaction containing 50 mM NaH2PO4, 100 mM NaCl and 0.1% BSA (pH 7.0) using 2 mM 4-Methylumbelliferyl N-acety...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/4/2015
Entry Details
US Patent

TargetProtein O-GlcNAcase(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 139961BDBM139961(US8901087, 211)
Affinity DataKi:  0.440nM ΔG°:  -53.4kJ/molepH: 7.0 T: 2°CAssay Description:Enzymatic reactions are carried out in a reaction containing 50 mM NaH2PO4, 100 mM NaCl and 0.1% BSA (pH 7.0) using 2 mM 4-Methylumbelliferyl N-acety...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/4/2015
Entry Details
US Patent

TargetProtein O-GlcNAcase(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 139942BDBM139942(US8901087, 65)
Affinity DataKi:  0.450nM ΔG°:  -53.3kJ/molepH: 7.0 T: 2°CAssay Description:Enzymatic reactions are carried out in a reaction containing 50 mM NaH2PO4, 100 mM NaCl and 0.1% BSA (pH 7.0) using 2 mM 4-Methylumbelliferyl N-acety...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/4/2015
Entry Details
US Patent

TargetProtein O-GlcNAcase(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 139948BDBM139948(US8901087, 80)
Affinity DataKi:  0.5nM ΔG°:  -53.1kJ/molepH: 7.0 T: 2°CAssay Description:Enzymatic reactions are carried out in a reaction containing 50 mM NaH2PO4, 100 mM NaCl and 0.1% BSA (pH 7.0) using 2 mM 4-Methylumbelliferyl N-acety...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/4/2015
Entry Details
US Patent

TargetProtein O-GlcNAcase(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 139950BDBM139950(US8901087, 91)
Affinity DataKi:  0.530nM ΔG°:  -52.9kJ/molepH: 7.0 T: 2°CAssay Description:Enzymatic reactions are carried out in a reaction containing 50 mM NaH2PO4, 100 mM NaCl and 0.1% BSA (pH 7.0) using 2 mM 4-Methylumbelliferyl N-acety...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/4/2015
Entry Details
US Patent

TargetProtein O-GlcNAcase(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 139929BDBM139929(US8901087, 8)
Affinity DataKi:  0.680nM ΔG°:  -52.3kJ/molepH: 7.0 T: 2°CAssay Description:Enzymatic reactions are carried out in a reaction containing 50 mM NaH2PO4, 100 mM NaCl and 0.1% BSA (pH 7.0) using 2 mM 4-Methylumbelliferyl N-acety...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/4/2015
Entry Details
US Patent

TargetProtein O-GlcNAcase(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 139938BDBM139938(US8901087, 53)
Affinity DataKi:  0.700nM ΔG°:  -52.3kJ/molepH: 7.0 T: 2°CAssay Description:Enzymatic reactions are carried out in a reaction containing 50 mM NaH2PO4, 100 mM NaCl and 0.1% BSA (pH 7.0) using 2 mM 4-Methylumbelliferyl N-acety...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/4/2015
Entry Details
US Patent

TargetProtein O-GlcNAcase(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 139932BDBM139932(US8901087, 25)
Affinity DataKi:  0.700nM ΔG°:  -52.3kJ/molepH: 7.0 T: 2°CAssay Description:Enzymatic reactions are carried out in a reaction containing 50 mM NaH2PO4, 100 mM NaCl and 0.1% BSA (pH 7.0) using 2 mM 4-Methylumbelliferyl N-acety...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/4/2015
Entry Details
US Patent

TargetProtein O-GlcNAcase(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 139958BDBM139958(US8901087, 181)
Affinity DataKi:  0.800nM ΔG°:  -51.9kJ/molepH: 7.0 T: 2°CAssay Description:Enzymatic reactions are carried out in a reaction containing 50 mM NaH2PO4, 100 mM NaCl and 0.1% BSA (pH 7.0) using 2 mM 4-Methylumbelliferyl N-acety...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/4/2015
Entry Details
US Patent

TargetProtein O-GlcNAcase(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 139956BDBM139956(US8901087, 141)
Affinity DataKi:  0.820nM ΔG°:  -51.9kJ/molepH: 7.0 T: 2°CAssay Description:Enzymatic reactions are carried out in a reaction containing 50 mM NaH2PO4, 100 mM NaCl and 0.1% BSA (pH 7.0) using 2 mM 4-Methylumbelliferyl N-acety...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/4/2015
Entry Details
US Patent

TargetProtein O-GlcNAcase(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 139927BDBM139927(US8901087, 3)
Affinity DataKi:  0.900nM ΔG°:  -51.6kJ/molepH: 7.0 T: 2°CAssay Description:Enzymatic reactions are carried out in a reaction containing 50 mM NaH2PO4, 100 mM NaCl and 0.1% BSA (pH 7.0) using 2 mM 4-Methylumbelliferyl N-acety...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/4/2015
Entry Details
US Patent

TargetProtein O-GlcNAcase(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 139935BDBM139935(US8901087, 42)
Affinity DataKi:  1.03nM ΔG°:  -51.3kJ/molepH: 7.0 T: 2°CAssay Description:Enzymatic reactions are carried out in a reaction containing 50 mM NaH2PO4, 100 mM NaCl and 0.1% BSA (pH 7.0) using 2 mM 4-Methylumbelliferyl N-acety...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/4/2015
Entry Details
US Patent

TargetProtein O-GlcNAcase(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 139943BDBM139943(US8901087, 67)
Affinity DataKi:  1.25nM ΔG°:  -50.8kJ/molepH: 7.0 T: 2°CAssay Description:Enzymatic reactions are carried out in a reaction containing 50 mM NaH2PO4, 100 mM NaCl and 0.1% BSA (pH 7.0) using 2 mM 4-Methylumbelliferyl N-acety...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/4/2015
Entry Details
US Patent

TargetProtein O-GlcNAcase(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 139957BDBM139957(US8901087, 159)
Affinity DataKi:  1.25nM ΔG°:  -50.8kJ/molepH: 7.0 T: 2°CAssay Description:Enzymatic reactions are carried out in a reaction containing 50 mM NaH2PO4, 100 mM NaCl and 0.1% BSA (pH 7.0) using 2 mM 4-Methylumbelliferyl N-acety...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/4/2015
Entry Details
US Patent

TargetProtein O-GlcNAcase(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 139953BDBM139953(US8901087, 98)
Affinity DataKi:  1.43nM ΔG°:  -50.5kJ/molepH: 7.0 T: 2°CAssay Description:Enzymatic reactions are carried out in a reaction containing 50 mM NaH2PO4, 100 mM NaCl and 0.1% BSA (pH 7.0) using 2 mM 4-Methylumbelliferyl N-acety...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/4/2015
Entry Details
US Patent

TargetProtein O-GlcNAcase(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 139962BDBM139962(US8901087, 215)
Affinity DataKi:  1.80nM ΔG°:  -49.9kJ/molepH: 7.0 T: 2°CAssay Description:Enzymatic reactions are carried out in a reaction containing 50 mM NaH2PO4, 100 mM NaCl and 0.1% BSA (pH 7.0) using 2 mM 4-Methylumbelliferyl N-acety...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/4/2015
Entry Details
US Patent

TargetProtein O-GlcNAcase(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 139940BDBM139940(US8901087, 61)
Affinity DataKi:  2.46nM ΔG°:  -49.1kJ/molepH: 7.0 T: 2°CAssay Description:Enzymatic reactions are carried out in a reaction containing 50 mM NaH2PO4, 100 mM NaCl and 0.1% BSA (pH 7.0) using 2 mM 4-Methylumbelliferyl N-acety...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/4/2015
Entry Details
US Patent

TargetProtein O-GlcNAcase(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 139928BDBM139928(US8901087, 4)
Affinity DataKi:  3.10nM ΔG°:  -48.6kJ/molepH: 7.0 T: 2°CAssay Description:Enzymatic reactions are carried out in a reaction containing 50 mM NaH2PO4, 100 mM NaCl and 0.1% BSA (pH 7.0) using 2 mM 4-Methylumbelliferyl N-acety...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/4/2015
Entry Details
US Patent

TargetProtein O-GlcNAcase(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 139960BDBM139960(US8901087, 203)
Affinity DataKi:  3.16nM ΔG°:  -48.5kJ/molepH: 7.0 T: 2°CAssay Description:Enzymatic reactions are carried out in a reaction containing 50 mM NaH2PO4, 100 mM NaCl and 0.1% BSA (pH 7.0) using 2 mM 4-Methylumbelliferyl N-acety...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/4/2015
Entry Details
US Patent

TargetProtein O-GlcNAcase(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 139955BDBM139955(US8901087, 105)
Affinity DataKi:  3.40nM ΔG°:  -48.3kJ/molepH: 7.0 T: 2°CAssay Description:Enzymatic reactions are carried out in a reaction containing 50 mM NaH2PO4, 100 mM NaCl and 0.1% BSA (pH 7.0) using 2 mM 4-Methylumbelliferyl N-acety...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/4/2015
Entry Details
US Patent

TargetProtein O-GlcNAcase(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 139954BDBM139954(US8901087, 104)
Affinity DataKi:  3.63nM ΔG°:  -48.2kJ/molepH: 7.0 T: 2°CAssay Description:Enzymatic reactions are carried out in a reaction containing 50 mM NaH2PO4, 100 mM NaCl and 0.1% BSA (pH 7.0) using 2 mM 4-Methylumbelliferyl N-acety...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/4/2015
Entry Details
US Patent

TargetProtein O-GlcNAcase(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 139937BDBM139937(US8901087, 51)
Affinity DataKi:  5.10nM ΔG°:  -47.3kJ/molepH: 7.0 T: 2°CAssay Description:Enzymatic reactions are carried out in a reaction containing 50 mM NaH2PO4, 100 mM NaCl and 0.1% BSA (pH 7.0) using 2 mM 4-Methylumbelliferyl N-acety...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/4/2015
Entry Details
US Patent

TargetProtein O-GlcNAcase(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 139949BDBM139949(US8901087, 82)
Affinity DataKi:  5.84nM ΔG°:  -47.0kJ/molepH: 7.0 T: 2°CAssay Description:Enzymatic reactions are carried out in a reaction containing 50 mM NaH2PO4, 100 mM NaCl and 0.1% BSA (pH 7.0) using 2 mM 4-Methylumbelliferyl N-acety...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/4/2015
Entry Details
US Patent

TargetProtein O-GlcNAcase(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 139936BDBM139936(US8901087, 47)
Affinity DataKi:  6.40nM ΔG°:  -46.8kJ/molepH: 7.0 T: 2°CAssay Description:Enzymatic reactions are carried out in a reaction containing 50 mM NaH2PO4, 100 mM NaCl and 0.1% BSA (pH 7.0) using 2 mM 4-Methylumbelliferyl N-acety...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/4/2015
Entry Details
US Patent

TargetProtein O-GlcNAcase(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 139934BDBM139934(US8901087, 40)
Affinity DataKi:  7.95nM ΔG°:  -46.2kJ/molepH: 7.0 T: 2°CAssay Description:Enzymatic reactions are carried out in a reaction containing 50 mM NaH2PO4, 100 mM NaCl and 0.1% BSA (pH 7.0) using 2 mM 4-Methylumbelliferyl N-acety...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/4/2015
Entry Details
US Patent

TargetProtein O-GlcNAcase(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 139945BDBM139945(US8901087, 71)
Affinity DataKi:  9.12nM ΔG°:  -45.9kJ/molepH: 7.0 T: 2°CAssay Description:Enzymatic reactions are carried out in a reaction containing 50 mM NaH2PO4, 100 mM NaCl and 0.1% BSA (pH 7.0) using 2 mM 4-Methylumbelliferyl N-acety...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/4/2015
Entry Details
US Patent

TargetProtein O-GlcNAcase(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 139944BDBM139944(US8901087, 69)
Affinity DataKi:  9.36nM ΔG°:  -45.8kJ/molepH: 7.0 T: 2°CAssay Description:Enzymatic reactions are carried out in a reaction containing 50 mM NaH2PO4, 100 mM NaCl and 0.1% BSA (pH 7.0) using 2 mM 4-Methylumbelliferyl N-acety...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/4/2015
Entry Details
US Patent

TargetProtein O-GlcNAcase(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 139947BDBM139947(US8901087, 77)
Affinity DataKi:  16.3nM ΔG°:  -44.5kJ/molepH: 7.0 T: 2°CAssay Description:Enzymatic reactions are carried out in a reaction containing 50 mM NaH2PO4, 100 mM NaCl and 0.1% BSA (pH 7.0) using 2 mM 4-Methylumbelliferyl N-acety...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/4/2015
Entry Details
US Patent