Compile Data Set for Download or QSAR
Report error Found 175 Enz. Inhib. hit(s) with all data for entry = 6615
TargetNeuronal acetylcholine receptor subunit alpha-4(Human)
Targacept

US Patent
LigandChemical structure of BindingDB Monomer ID 50397942BDBM50397942(CHEMBL2179534)
Affinity DataKi:  1.5nM ΔG°:  -49.7kJ/moleT: 2°CAssay Description:The binding of [3H]MLA was measured using a modification of the methods of Davies et al., Neuropharmacol. 38: 679 (1999). [3H]MLA (Specific Activity=...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2015
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 50397942BDBM50397942(CHEMBL2179534)
Affinity DataKi:  1.5nM ΔG°:  -49.7kJ/moleT: 2°CAssay Description:The binding of [3H]MLA was measured using a modification of the methods of Davies et al., Neuropharmacol. 38: 679 (1999). [3H]MLA (Specific Activity=...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2015
Entry Details
US Patent

TargetNeuronal acetylcholine receptor subunit alpha-4(Human)
Targacept

US Patent
LigandChemical structure of BindingDB Monomer ID 141885BDBM141885(US8921410, Table 2 Compound 20)
Affinity DataKi:  1.60nM ΔG°:  -49.5kJ/moleT: 2°CAssay Description:The binding of [3H]MLA was measured using a modification of the methods of Davies et al., Neuropharmacol. 38: 679 (1999). [3H]MLA (Specific Activity=...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2015
Entry Details
US Patent

TargetNeuronal acetylcholine receptor subunit alpha-4(Human)
Targacept

US Patent
LigandChemical structure of BindingDB Monomer ID 50397929BDBM50397929(CHEMBL2179547)
Affinity DataKi:  1.70nM ΔG°:  -49.4kJ/moleT: 2°CAssay Description:The binding of [3H]MLA was measured using a modification of the methods of Davies et al., Neuropharmacol. 38: 679 (1999). [3H]MLA (Specific Activity=...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2015
Entry Details
US Patent

TargetNeuronal acetylcholine receptor subunit alpha-4(Human)
Targacept

US Patent
LigandChemical structure of BindingDB Monomer ID 50397888BDBM50397888(CHEMBL2179531)
Affinity DataKi:  2.40nM ΔG°:  -48.5kJ/moleT: 2°CAssay Description:The binding of [3H]MLA was measured using a modification of the methods of Davies et al., Neuropharmacol. 38: 679 (1999). [3H]MLA (Specific Activity=...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2015
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 50397888BDBM50397888(CHEMBL2179531)
Affinity DataKi:  2.80nM ΔG°:  -48.2kJ/moleT: 2°CAssay Description:The binding of [3H]MLA was measured using a modification of the methods of Davies et al., Neuropharmacol. 38: 679 (1999). [3H]MLA (Specific Activity=...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2015
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 141885BDBM141885(US8921410, Table 2 Compound 20)
Affinity DataKi:  4nM ΔG°:  -47.3kJ/moleT: 2°CAssay Description:The binding of [3H]MLA was measured using a modification of the methods of Davies et al., Neuropharmacol. 38: 679 (1999). [3H]MLA (Specific Activity=...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2015
Entry Details
US Patent

TargetNeuronal acetylcholine receptor subunit alpha-4(Human)
Targacept

US Patent
LigandChemical structure of BindingDB Monomer ID 50397936BDBM50397936(CHEMBL2179540)
Affinity DataKi:  4.60nM ΔG°:  -46.9kJ/moleT: 2°CAssay Description:The binding of [3H]MLA was measured using a modification of the methods of Davies et al., Neuropharmacol. 38: 679 (1999). [3H]MLA (Specific Activity=...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2015
Entry Details
US Patent

TargetNeuronal acetylcholine receptor subunit alpha-4(Human)
Targacept

US Patent
LigandChemical structure of BindingDB Monomer ID 141867BDBM141867(US8921410, Table 1 Compound 33)
Affinity DataKi:  4.90nM ΔG°:  -46.8kJ/moleT: 2°CAssay Description:The binding of [3H]MLA was measured using a modification of the methods of Davies et al., Neuropharmacol. 38: 679 (1999). [3H]MLA (Specific Activity=...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2015
Entry Details
US Patent

TargetNeuronal acetylcholine receptor subunit alpha-4(Human)
Targacept

US Patent
LigandChemical structure of BindingDB Monomer ID 141887BDBM141887(US8921410, Table 2 Compound 25)
Affinity DataKi:  5.20nM ΔG°:  -46.6kJ/moleT: 2°CAssay Description:The binding of [3H]MLA was measured using a modification of the methods of Davies et al., Neuropharmacol. 38: 679 (1999). [3H]MLA (Specific Activity=...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2015
Entry Details
US Patent

TargetNeuronal acetylcholine receptor subunit alpha-4(Human)
Targacept

US Patent
LigandChemical structure of BindingDB Monomer ID 50397932BDBM50397932(CHEMBL2179544)
Affinity DataKi:  5.20nM ΔG°:  -46.6kJ/moleT: 2°CAssay Description:The binding of [3H]MLA was measured using a modification of the methods of Davies et al., Neuropharmacol. 38: 679 (1999). [3H]MLA (Specific Activity=...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2015
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 141875BDBM141875(US8921410, Table 2 Compound 8)
Affinity DataKi:  5.90nM ΔG°:  -46.3kJ/moleT: 2°CAssay Description:The binding of [3H]MLA was measured using a modification of the methods of Davies et al., Neuropharmacol. 38: 679 (1999). [3H]MLA (Specific Activity=...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2015
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 141883BDBM141883(US8921410, Table 2 Compound 18)
Affinity DataKi:  6.30nM ΔG°:  -46.2kJ/moleT: 2°CAssay Description:The binding of [3H]MLA was measured using a modification of the methods of Davies et al., Neuropharmacol. 38: 679 (1999). [3H]MLA (Specific Activity=...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2015
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 50397936BDBM50397936(CHEMBL2179540)
Affinity DataKi:  6.40nM ΔG°:  -46.1kJ/moleT: 2°CAssay Description:The binding of [3H]MLA was measured using a modification of the methods of Davies et al., Neuropharmacol. 38: 679 (1999). [3H]MLA (Specific Activity=...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2015
Entry Details
US Patent

TargetNeuronal acetylcholine receptor subunit alpha-4(Human)
Targacept

US Patent
LigandChemical structure of BindingDB Monomer ID 50397933BDBM50397933(CHEMBL2179543)
Affinity DataKi:  7.30nM ΔG°:  -45.8kJ/moleT: 2°CAssay Description:The binding of [3H]MLA was measured using a modification of the methods of Davies et al., Neuropharmacol. 38: 679 (1999). [3H]MLA (Specific Activity=...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2015
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 141887BDBM141887(US8921410, Table 2 Compound 25)
Affinity DataKi:  7.5nM ΔG°:  -45.8kJ/moleT: 2°CAssay Description:The binding of [3H]MLA was measured using a modification of the methods of Davies et al., Neuropharmacol. 38: 679 (1999). [3H]MLA (Specific Activity=...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2015
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 50397893BDBM50397893(CHEMBL2179526)
Affinity DataKi:  8.30nM ΔG°:  -45.5kJ/moleT: 2°CAssay Description:The binding of [3H]MLA was measured using a modification of the methods of Davies et al., Neuropharmacol. 38: 679 (1999). [3H]MLA (Specific Activity=...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2015
Entry Details
US Patent

TargetNeuronal acetylcholine receptor subunit alpha-4(Human)
Targacept

US Patent
LigandChemical structure of BindingDB Monomer ID 141891BDBM141891(US8921410, Table 2 Compound 30)
Affinity DataKi:  8.70nM ΔG°:  -45.4kJ/moleT: 2°CAssay Description:The binding of [3H]MLA was measured using a modification of the methods of Davies et al., Neuropharmacol. 38: 679 (1999). [3H]MLA (Specific Activity=...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2015
Entry Details
US Patent

TargetNeuronal acetylcholine receptor subunit alpha-4(Human)
Targacept

US Patent
LigandChemical structure of BindingDB Monomer ID 50397913BDBM50397913(CHEMBL2179516)
Affinity DataKi:  9.20nM ΔG°:  -45.3kJ/moleT: 2°CAssay Description:The binding of [3H]MLA was measured using a modification of the methods of Davies et al., Neuropharmacol. 38: 679 (1999). [3H]MLA (Specific Activity=...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2015
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 141879BDBM141879(US8921410, Table 2 Compound 12)
Affinity DataKi:  9.5nM ΔG°:  -45.2kJ/moleT: 2°CAssay Description:The binding of [3H]MLA was measured using a modification of the methods of Davies et al., Neuropharmacol. 38: 679 (1999). [3H]MLA (Specific Activity=...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2015
Entry Details
US Patent

TargetNeuronal acetylcholine receptor subunit alpha-4(Human)
Targacept

US Patent
LigandChemical structure of BindingDB Monomer ID 50397889BDBM50397889(CHEMBL2179530)
Affinity DataKi:  9.70nM ΔG°:  -45.1kJ/moleT: 2°CAssay Description:The binding of [3H]MLA was measured using a modification of the methods of Davies et al., Neuropharmacol. 38: 679 (1999). [3H]MLA (Specific Activity=...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2015
Entry Details
US Patent

TargetNeuronal acetylcholine receptor subunit alpha-4(Human)
Targacept

US Patent
LigandChemical structure of BindingDB Monomer ID 50397899BDBM50397899(CHEMBL2179967)
Affinity DataKi:  9.90nM ΔG°:  -45.1kJ/moleT: 2°CAssay Description:The binding of [3H]MLA was measured using a modification of the methods of Davies et al., Neuropharmacol. 38: 679 (1999). [3H]MLA (Specific Activity=...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2015
Entry Details
US Patent

TargetNeuronal acetylcholine receptor subunit alpha-4(Human)
Targacept

US Patent
LigandChemical structure of BindingDB Monomer ID 141886BDBM141886(US8921410, Table 2 Compound 24)
Affinity DataKi:  10nM ΔG°:  -45.0kJ/moleT: 2°CAssay Description:The binding of [3H]MLA was measured using a modification of the methods of Davies et al., Neuropharmacol. 38: 679 (1999). [3H]MLA (Specific Activity=...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2015
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 50397929BDBM50397929(CHEMBL2179547)
Affinity DataKi:  12nM ΔG°:  -44.6kJ/moleT: 2°CAssay Description:The binding of [3H]MLA was measured using a modification of the methods of Davies et al., Neuropharmacol. 38: 679 (1999). [3H]MLA (Specific Activity=...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2015
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 141884BDBM141884(US8921410, Table 2 Compound 19)
Affinity DataKi:  12nM ΔG°:  -44.6kJ/moleT: 2°CAssay Description:The binding of [3H]MLA was measured using a modification of the methods of Davies et al., Neuropharmacol. 38: 679 (1999). [3H]MLA (Specific Activity=...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2015
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 50397932BDBM50397932(CHEMBL2179544)
Affinity DataKi:  13nM ΔG°:  -44.4kJ/moleT: 2°CAssay Description:The binding of [3H]MLA was measured using a modification of the methods of Davies et al., Neuropharmacol. 38: 679 (1999). [3H]MLA (Specific Activity=...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2015
Entry Details
US Patent

TargetNeuronal acetylcholine receptor subunit alpha-4(Human)
Targacept

US Patent
LigandChemical structure of BindingDB Monomer ID 50397935BDBM50397935(CHEMBL2179541)
Affinity DataKi:  14nM ΔG°:  -44.2kJ/moleT: 2°CAssay Description:The binding of [3H]MLA was measured using a modification of the methods of Davies et al., Neuropharmacol. 38: 679 (1999). [3H]MLA (Specific Activity=...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2015
Entry Details
US Patent

TargetNeuronal acetylcholine receptor subunit alpha-4(Human)
Targacept

US Patent
LigandChemical structure of BindingDB Monomer ID 141872BDBM141872(US8921410, Table 1 Compound 41)
Affinity DataKi:  14nM ΔG°:  -44.2kJ/moleT: 2°CAssay Description:The binding of [3H]MLA was measured using a modification of the methods of Davies et al., Neuropharmacol. 38: 679 (1999). [3H]MLA (Specific Activity=...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2015
Entry Details
US Patent

TargetNeuronal acetylcholine receptor subunit alpha-4(Human)
Targacept

US Patent
LigandChemical structure of BindingDB Monomer ID 141868BDBM141868(US8921410, Table 1 Compound 35)
Affinity DataKi:  14nM ΔG°:  -44.2kJ/moleT: 2°CAssay Description:The binding of [3H]MLA was measured using a modification of the methods of Davies et al., Neuropharmacol. 38: 679 (1999). [3H]MLA (Specific Activity=...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2015
Entry Details
US Patent

TargetNeuronal acetylcholine receptor subunit alpha-4(Human)
Targacept

US Patent
LigandChemical structure of BindingDB Monomer ID 141856BDBM141856(US8921410, Table 1 Compound 20)
Affinity DataKi:  14nM ΔG°:  -44.2kJ/moleT: 2°CAssay Description:The binding of [3H]MLA was measured using a modification of the methods of Davies et al., Neuropharmacol. 38: 679 (1999). [3H]MLA (Specific Activity=...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2015
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 50397913BDBM50397913(CHEMBL2179516)
Affinity DataKi:  15nM ΔG°:  -44.1kJ/moleT: 2°CAssay Description:The binding of [3H]MLA was measured using a modification of the methods of Davies et al., Neuropharmacol. 38: 679 (1999). [3H]MLA (Specific Activity=...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2015
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 50397933BDBM50397933(CHEMBL2179543)
Affinity DataKi:  15nM ΔG°:  -44.1kJ/moleT: 2°CAssay Description:The binding of [3H]MLA was measured using a modification of the methods of Davies et al., Neuropharmacol. 38: 679 (1999). [3H]MLA (Specific Activity=...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2015
Entry Details
US Patent

TargetNeuronal acetylcholine receptor subunit alpha-4(Human)
Targacept

US Patent
LigandChemical structure of BindingDB Monomer ID 50397893BDBM50397893(CHEMBL2179526)
Affinity DataKi:  16nM ΔG°:  -43.9kJ/moleT: 2°CAssay Description:The binding of [3H]MLA was measured using a modification of the methods of Davies et al., Neuropharmacol. 38: 679 (1999). [3H]MLA (Specific Activity=...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2015
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 141850BDBM141850(US8921410, Table 1 Compound 12)
Affinity DataKi:  17nM ΔG°:  -43.8kJ/moleT: 2°CAssay Description:The binding of [3H]MLA was measured using a modification of the methods of Davies et al., Neuropharmacol. 38: 679 (1999). [3H]MLA (Specific Activity=...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2015
Entry Details
US Patent

TargetNeuronal acetylcholine receptor subunit alpha-4(Human)
Targacept

US Patent
LigandChemical structure of BindingDB Monomer ID 50397928BDBM50397928(CHEMBL2179548)
Affinity DataKi:  17nM ΔG°:  -43.8kJ/moleT: 2°CAssay Description:The binding of [3H]MLA was measured using a modification of the methods of Davies et al., Neuropharmacol. 38: 679 (1999). [3H]MLA (Specific Activity=...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2015
Entry Details
US Patent

TargetNeuronal acetylcholine receptor subunit alpha-4(Human)
Targacept

US Patent
LigandChemical structure of BindingDB Monomer ID 50397895BDBM50397895(CHEMBL2179524)
Affinity DataKi:  18nM ΔG°:  -43.6kJ/moleT: 2°CAssay Description:The binding of [3H]MLA was measured using a modification of the methods of Davies et al., Neuropharmacol. 38: 679 (1999). [3H]MLA (Specific Activity=...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2015
Entry Details
US Patent

TargetNeuronal acetylcholine receptor subunit alpha-4(Human)
Targacept

US Patent
LigandChemical structure of BindingDB Monomer ID 50397886BDBM50397886(CHEMBL2179533)
Affinity DataKi:  18nM ΔG°:  -43.6kJ/moleT: 2°CAssay Description:The binding of [3H]MLA was measured using a modification of the methods of Davies et al., Neuropharmacol. 38: 679 (1999). [3H]MLA (Specific Activity=...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2015
Entry Details
US Patent

TargetNeuronal acetylcholine receptor subunit alpha-4(Human)
Targacept

US Patent
LigandChemical structure of BindingDB Monomer ID 141875BDBM141875(US8921410, Table 2 Compound 8)
Affinity DataKi:  18nM ΔG°:  -43.6kJ/moleT: 2°CAssay Description:The binding of [3H]MLA was measured using a modification of the methods of Davies et al., Neuropharmacol. 38: 679 (1999). [3H]MLA (Specific Activity=...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2015
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 141848BDBM141848(US8921410, Table 1 Compound 6)
Affinity DataKi:  19nM ΔG°:  -43.5kJ/moleT: 2°CAssay Description:The binding of [3H]MLA was measured using a modification of the methods of Davies et al., Neuropharmacol. 38: 679 (1999). [3H]MLA (Specific Activity=...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2015
Entry Details
US Patent

TargetNeuronal acetylcholine receptor subunit alpha-4(Human)
Targacept

US Patent
LigandChemical structure of BindingDB Monomer ID 141848BDBM141848(US8921410, Table 1 Compound 6)
Affinity DataKi:  19nM ΔG°:  -43.5kJ/moleT: 2°CAssay Description:The binding of [3H]MLA was measured using a modification of the methods of Davies et al., Neuropharmacol. 38: 679 (1999). [3H]MLA (Specific Activity=...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2015
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 141864BDBM141864(US8921410, Table 1 Compound 28)
Affinity DataKi:  20nM ΔG°:  -43.4kJ/moleT: 2°CAssay Description:The binding of [3H]MLA was measured using a modification of the methods of Davies et al., Neuropharmacol. 38: 679 (1999). [3H]MLA (Specific Activity=...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2015
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 141878BDBM141878(US8921410, Table 2 Compound 11)
Affinity DataKi:  20nM ΔG°:  -43.4kJ/moleT: 2°CAssay Description:The binding of [3H]MLA was measured using a modification of the methods of Davies et al., Neuropharmacol. 38: 679 (1999). [3H]MLA (Specific Activity=...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2015
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 50397900BDBM50397900(CHEMBL2179966)
Affinity DataKi:  20nM ΔG°:  -43.4kJ/moleT: 2°CAssay Description:The binding of [3H]MLA was measured using a modification of the methods of Davies et al., Neuropharmacol. 38: 679 (1999). [3H]MLA (Specific Activity=...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2015
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 141867BDBM141867(US8921410, Table 1 Compound 33)
Affinity DataKi:  20nM ΔG°:  -43.4kJ/moleT: 2°CAssay Description:The binding of [3H]MLA was measured using a modification of the methods of Davies et al., Neuropharmacol. 38: 679 (1999). [3H]MLA (Specific Activity=...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2015
Entry Details
US Patent

TargetNeuronal acetylcholine receptor subunit alpha-4(Human)
Targacept

US Patent
LigandChemical structure of BindingDB Monomer ID 141866BDBM141866(US8921410, Table 1 Compound 30)
Affinity DataKi:  21nM ΔG°:  -43.2kJ/moleT: 2°CAssay Description:The binding of [3H]MLA was measured using a modification of the methods of Davies et al., Neuropharmacol. 38: 679 (1999). [3H]MLA (Specific Activity=...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2015
Entry Details
US Patent

TargetNeuronal acetylcholine receptor subunit alpha-4(Human)
Targacept

US Patent
LigandChemical structure of BindingDB Monomer ID 141879BDBM141879(US8921410, Table 2 Compound 12)
Affinity DataKi:  21nM ΔG°:  -43.2kJ/moleT: 2°CAssay Description:The binding of [3H]MLA was measured using a modification of the methods of Davies et al., Neuropharmacol. 38: 679 (1999). [3H]MLA (Specific Activity=...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2015
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 50397889BDBM50397889(CHEMBL2179530)
Affinity DataKi:  21nM ΔG°:  -43.2kJ/moleT: 2°CAssay Description:The binding of [3H]MLA was measured using a modification of the methods of Davies et al., Neuropharmacol. 38: 679 (1999). [3H]MLA (Specific Activity=...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2015
Entry Details
US Patent

TargetNeuronal acetylcholine receptor subunit alpha-4(Human)
Targacept

US Patent
LigandChemical structure of BindingDB Monomer ID 50397892BDBM50397892(CHEMBL2179527)
Affinity DataKi:  21nM ΔG°:  -43.2kJ/moleT: 2°CAssay Description:The binding of [3H]MLA was measured using a modification of the methods of Davies et al., Neuropharmacol. 38: 679 (1999). [3H]MLA (Specific Activity=...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2015
Entry Details
US Patent

TargetNeuronal acetylcholine receptor subunit alpha-4(Human)
Targacept

US Patent
LigandChemical structure of BindingDB Monomer ID 141864BDBM141864(US8921410, Table 1 Compound 28)
Affinity DataKi:  22nM ΔG°:  -43.1kJ/moleT: 2°CAssay Description:The binding of [3H]MLA was measured using a modification of the methods of Davies et al., Neuropharmacol. 38: 679 (1999). [3H]MLA (Specific Activity=...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2015
Entry Details
US Patent

TargetNeuronal acetylcholine receptor subunit alpha-4(Human)
Targacept

US Patent
LigandChemical structure of BindingDB Monomer ID 141894BDBM141894(US8921410, Table 2 Compound 33)
Affinity DataKi:  23nM ΔG°:  -43.0kJ/moleT: 2°CAssay Description:The binding of [3H]MLA was measured using a modification of the methods of Davies et al., Neuropharmacol. 38: 679 (1999). [3H]MLA (Specific Activity=...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2015
Entry Details
US Patent

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