Compile Data Set for Download or QSAR
Report error Found 26 Enz. Inhib. hit(s) with all data for entry = 6636
LigandChemical structure of BindingDB Monomer ID 142416BDBM142416(US8927738, 2-[2-(2-Furan-3-yl-1H-imidazol-4-yl)-et...)
Affinity DataIC50: 0.270nMT: 2°CAssay Description:A PDE10A assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2015
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 142410BDBM142410(US8927738, 5,8-Dimethyl-2-[2-(2-thiophen-2-yl-1H-i...)
Affinity DataIC50: 0.340nMT: 2°CAssay Description:A PDE10A assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2015
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 142414BDBM142414(US8927738, 5,8-Dimethyl-2-[2-(2-thiophen-2-yl-1H-i...)
Affinity DataIC50: 0.400nMT: 2°CAssay Description:A PDE10A assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2015
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 142412BDBM142412(US8927738, 2-[2-(2-Furan-2-yl-1H-imidazol-4-yl)-et...)
Affinity DataIC50: 0.620nMT: 2°CAssay Description:A PDE10A assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2015
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 142415BDBM142415(US8927738, 5,8-Dimethyl-2-[2-(2-thiazol-2-yl-1H-im...)
Affinity DataIC50: 0.630nMT: 2°CAssay Description:A PDE10A assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2015
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 142413BDBM142413(US8927738, 2-[2-(2-Furan-3-yl-1H-imidazol-4-yl)-et...)
Affinity DataIC50: 0.650nMT: 2°CAssay Description:A PDE10A assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2015
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 142409BDBM142409(US8927738, 2-[2-(2-Furan-2-yl-1-methyl-1H-imidazol...)
Affinity DataIC50: 0.75nMT: 2°CAssay Description:A PDE10A assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2015
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 142417BDBM142417(US8927738, 2-[2-(2-Furan-2-yl-1H-imidazol-4-yl)-et...)
Affinity DataIC50: 0.970nMT: 2°CAssay Description:A PDE10A assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2015
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 50397979BDBM50397979(US8927738, 5,8-Dimethyl-2-[2-(1-methyl-2-thiophen-...)
Affinity DataIC50: 1nMT: 2°CAssay Description:A PDE10A assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2015
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 142406BDBM142406(US8927738, 2-[2-(2-Furan-2-yl-1-methyl-1H-imidazol...)
Affinity DataIC50: 1.10nMT: 2°CAssay Description:A PDE10A assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2015
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 142411BDBM142411(US8927738, 5,8-Dimethyl-2-[2-(2-thiazol-2-yl-1H-im...)
Affinity DataIC50: 1.60nMT: 2°CAssay Description:A PDE10A assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2015
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 142404BDBM142404(US8927738, 5,8-Dimethyl-2-[2-(2-thiazol-5-yl-1H-im...)
Affinity DataIC50: 3.10nMT: 2°CAssay Description:A PDE10A assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2015
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 142407BDBM142407(US8927738, 5,8-Dimethyl-2-[2-(2-thiazol-4-yl-1H-im...)
Affinity DataIC50: 3.5nMT: 2°CAssay Description:A PDE10A assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2015
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 142408BDBM142408(US8927738, 5,8-Dimethyl-2-[2-(2-thiazol-4-yl-1H-im...)
Affinity DataIC50: 3.5nMT: 2°CAssay Description:A PDE10A assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2015
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 142418BDBM142418(US8927738, 5,8-Dimethyl-2-{2-[1-methyl-2-(5-methyl...)
Affinity DataIC50: 3.5nMT: 2°CAssay Description:A PDE10A assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2015
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 142399BDBM142399(US8927738, 5,8-Dimethyl-2-[2-(2-phenyl-1H-imidazol...)
Affinity DataIC50: 4.20nMT: 2°CAssay Description:A PDE10A assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2015
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 142396BDBM142396(US8927738, 8-Methoxy-5-methyl-2-[2-(2-phenyl-1H-im...)
Affinity DataIC50: 5.90nMT: 2°CAssay Description:A PDE10A assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2015
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 142403BDBM142403(US8927738, 5,8-Dimethyl-2-[2-(2-thiazol-5-yl-1H-im...)
Affinity DataIC50: 6.5nMT: 2°CAssay Description:A PDE10A assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2015
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 142402BDBM142402(US8927738, 5,8-Dimethyl-2-[2-(1-methyl-2-thiazol-2...)
Affinity DataIC50: 7.70nMT: 2°CAssay Description:A PDE10A assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2015
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 142401BDBM142401(US8927738, 8-Methoxy-5-methyl-2-[2-(1-methyl-2-thi...)
Affinity DataIC50: 9nMT: 2°CAssay Description:A PDE10A assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2015
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 142419BDBM142419(US8927738, 5,8-Dimethyl-2-[2-(1-methyl-2-thiazol-4...)
Affinity DataIC50: 11nMT: 2°CAssay Description:A PDE10A assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2015
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 142420BDBM142420(US8927738, 2-{2-[2-(4-Fluoro-phenyl)-1H-imidazol-4...)
Affinity DataIC50: 12nMT: 2°CAssay Description:A PDE10A assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2015
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 142405BDBM142405(US8927738, 5,8-Dimethyl-2-[2-(1-methyl-2-thiazol-5...)
Affinity DataIC50: 22nMT: 2°CAssay Description:A PDE10A assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2015
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 142398BDBM142398(US8927738, 8-Ethyl-5-methyl-2-[2-(1-methyl-2-pheny...)
Affinity DataIC50: 23nMT: 2°CAssay Description:A PDE10A assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2015
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 142400BDBM142400(US8927738, 5,8-Dimethyl-2-[2-(1-methyl-2-phenyl-1H...)
Affinity DataIC50: 45nMT: 2°CAssay Description:A PDE10A assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2015
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 142397BDBM142397(US8927738, 8-Methoxy-5-methyl-2-[2-(1-methyl-2-phe...)
Affinity DataIC50: 79nMT: 2°CAssay Description:A PDE10A assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2015
Entry Details
US Patent