Compile Data Set for Download or QSAR
Report error Found 205 Enz. Inhib. hit(s) with all data for entry = 6700
TargetCyclin-dependent kinase 4(Human)
Novartis

US Patent
LigandPNGBDBM148254(US8962630, 63)
Affinity DataIC50: 8nMpH: 7.5 T: 2°CAssay Description:A 384-well microtiter Lance TR-FRET (time-resolved-fluorescence energy transfer) endpoint assay was used for CDK4/cyclin D1 kinase activity measureme...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2015
Entry Details
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TargetCyclin-dependent kinase 4(Human)
Novartis

US Patent
LigandPNGBDBM148264(US8962630, 74 | Ribociclib | LEE011 | Kisqali | 7-...)
Affinity DataIC50: 10nMpH: 7.5 T: 2°CAssay Description:A 384-well microtiter Lance TR-FRET (time-resolved-fluorescence energy transfer) endpoint assay was used for CDK4/cyclin D1 kinase activity measureme...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2015
Entry Details
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TargetCyclin-dependent kinase 4(Human)
Novartis

US Patent
LigandPNGBDBM148218(US8962630, 26)
Affinity DataIC50: 26nMpH: 7.5 T: 2°CAssay Description:A 384-well microtiter Lance TR-FRET (time-resolved-fluorescence energy transfer) endpoint assay was used for CDK4/cyclin D1 kinase activity measureme...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2015
Entry Details
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TargetCyclin-dependent kinase 1(Human)
Novartis

US Patent
LigandPNGBDBM148210(US8962630, 18)
Affinity DataIC50: 1.10E+3nMT: 2°CAssay Description:A 384-well microtiter IMAP-FPT (Molecular Devices Trade Mark Technology) endpoint assay was used for CDK1/cyclin B kinase activity measurements. The ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2015
Entry Details
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TargetCyclin-dependent kinase 1(Human)
Novartis

US Patent
LigandPNGBDBM148203(US8962630, 11)
Affinity DataIC50: 1.30E+3nMT: 2°CAssay Description:A 384-well microtiter IMAP-FPT (Molecular Devices Trade Mark Technology) endpoint assay was used for CDK1/cyclin B kinase activity measurements. The ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2015
Entry Details
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TargetCyclin-dependent kinase 1(Human)
Novartis

US Patent
LigandPNGBDBM148238(US8962630, 47)
Affinity DataIC50: 2.60E+3nMT: 2°CAssay Description:A 384-well microtiter IMAP-FPT (Molecular Devices Trade Mark Technology) endpoint assay was used for CDK1/cyclin B kinase activity measurements. The ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2015
Entry Details
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TargetCyclin-dependent kinase 2(Human)
Novartis

US Patent
LigandPNGBDBM148210(US8962630, 18)
Affinity DataIC50: 2.80E+3nMAssay Description:The assay was run under the conditions identical to that for CDK1/cyclin B except 0.25 nM CDK1/cyclin B was replaced with 0.3 nM CDK2/cyclin A. A 384...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2015
Entry Details
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TargetCyclin-dependent kinase 2(Human)
Novartis

US Patent
LigandPNGBDBM148226(US8962630, 35)
Affinity DataIC50: 2.90E+3nMAssay Description:The assay was run under the conditions identical to that for CDK1/cyclin B except 0.25 nM CDK1/cyclin B was replaced with 0.3 nM CDK2/cyclin A. A 384...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2015
Entry Details
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TargetCyclin-dependent kinase 2(Human)
Novartis

US Patent
LigandPNGBDBM148203(US8962630, 11)
Affinity DataIC50: 3.50E+3nMAssay Description:The assay was run under the conditions identical to that for CDK1/cyclin B except 0.25 nM CDK1/cyclin B was replaced with 0.3 nM CDK2/cyclin A. A 384...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2015
Entry Details
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TargetCyclin-dependent kinase 2(Human)
Novartis

US Patent
LigandPNGBDBM148232(US8962630, 41)
Affinity DataIC50: 4.70E+3nMAssay Description:The assay was run under the conditions identical to that for CDK1/cyclin B except 0.25 nM CDK1/cyclin B was replaced with 0.3 nM CDK2/cyclin A. A 384...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2015
Entry Details
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TargetCyclin-dependent kinase 1(Human)
Novartis

US Patent
LigandPNGBDBM148226(US8962630, 35)
Affinity DataIC50: 4.70E+3nMT: 2°CAssay Description:A 384-well microtiter IMAP-FPT (Molecular Devices Trade Mark Technology) endpoint assay was used for CDK1/cyclin B kinase activity measurements. The ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2015
Entry Details
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TargetCyclin-dependent kinase 2(Human)
Novartis

US Patent
LigandPNGBDBM148199(US8962630, 8)
Affinity DataIC50: 8.00E+3nMAssay Description:The assay was run under the conditions identical to that for CDK1/cyclin B except 0.25 nM CDK1/cyclin B was replaced with 0.3 nM CDK2/cyclin A. A 384...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2015
Entry Details
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TargetCyclin-dependent kinase 2(Human)
Novartis

US Patent
LigandPNGBDBM148238(US8962630, 47)
Affinity DataIC50: 8.30E+3nMAssay Description:The assay was run under the conditions identical to that for CDK1/cyclin B except 0.25 nM CDK1/cyclin B was replaced with 0.3 nM CDK2/cyclin A. A 384...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2015
Entry Details
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TargetCyclin-dependent kinase 1(Human)
Novartis

US Patent
LigandPNGBDBM148202(US8962630, 10A)
Affinity DataIC50: 1.20E+4nMT: 2°CAssay Description:A 384-well microtiter IMAP-FPT (Molecular Devices Trade Mark Technology) endpoint assay was used for CDK1/cyclin B kinase activity measurements. The ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2015
Entry Details
Go to US Patent

TargetCyclin-dependent kinase 1(Human)
Novartis

US Patent
LigandPNGBDBM148277(US8962630, 87)
Affinity DataIC50: 1.30E+4nMT: 2°CAssay Description:A 384-well microtiter IMAP-FPT (Molecular Devices Trade Mark Technology) endpoint assay was used for CDK1/cyclin B kinase activity measurements. The ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2015
Entry Details
Go to US Patent

TargetCyclin-dependent kinase 2(Human)
Novartis

US Patent
LigandPNGBDBM148202(US8962630, 10A)
Affinity DataIC50: 1.40E+4nMAssay Description:The assay was run under the conditions identical to that for CDK1/cyclin B except 0.25 nM CDK1/cyclin B was replaced with 0.3 nM CDK2/cyclin A. A 384...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2015
Entry Details
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TargetCyclin-dependent kinase 1(Human)
Novartis

US Patent
LigandPNGBDBM148199(US8962630, 8)
Affinity DataIC50: 1.40E+4nMT: 2°CAssay Description:A 384-well microtiter IMAP-FPT (Molecular Devices Trade Mark Technology) endpoint assay was used for CDK1/cyclin B kinase activity measurements. The ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2015
Entry Details
Go to US Patent

TargetCyclin-dependent kinase 1(Human)
Novartis

US Patent
LigandPNGBDBM148232(US8962630, 41)
Affinity DataIC50: 1.48E+4nMT: 2°CAssay Description:A 384-well microtiter IMAP-FPT (Molecular Devices Trade Mark Technology) endpoint assay was used for CDK1/cyclin B kinase activity measurements. The ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2015
Entry Details
Go to US Patent

TargetCyclin-dependent kinase 2(Human)
Novartis

US Patent
LigandPNGBDBM148223(US8962630, 32)
Affinity DataIC50: 1.50E+4nMAssay Description:The assay was run under the conditions identical to that for CDK1/cyclin B except 0.25 nM CDK1/cyclin B was replaced with 0.3 nM CDK2/cyclin A. A 384...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2015
Entry Details
Go to US Patent

TargetCyclin-dependent kinase 2(Human)
Novartis

US Patent
LigandPNGBDBM148250(US8962630, 59)
Affinity DataIC50: 1.50E+4nMAssay Description:The assay was run under the conditions identical to that for CDK1/cyclin B except 0.25 nM CDK1/cyclin B was replaced with 0.3 nM CDK2/cyclin A. A 384...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2015
Entry Details
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TargetCyclin-dependent kinase 2(Human)
Novartis

US Patent
LigandPNGBDBM148273(US8962630, 83)
Affinity DataIC50: 1.50E+4nMAssay Description:The assay was run under the conditions identical to that for CDK1/cyclin B except 0.25 nM CDK1/cyclin B was replaced with 0.3 nM CDK2/cyclin A. A 384...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2015
Entry Details
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TargetCyclin-dependent kinase 2(Human)
Novartis

US Patent
LigandPNGBDBM148196(US8962630, 4)
Affinity DataIC50: 1.50E+4nMAssay Description:The assay was run under the conditions identical to that for CDK1/cyclin B except 0.25 nM CDK1/cyclin B was replaced with 0.3 nM CDK2/cyclin A. A 384...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2015
Entry Details
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TargetCyclin-dependent kinase 2(Human)
Novartis

US Patent
LigandPNGBDBM148205(US8962630, 13)
Affinity DataIC50: 1.50E+4nMAssay Description:The assay was run under the conditions identical to that for CDK1/cyclin B except 0.25 nM CDK1/cyclin B was replaced with 0.3 nM CDK2/cyclin A. A 384...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2015
Entry Details
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TargetCyclin-dependent kinase 2(Human)
Novartis

US Patent
LigandPNGBDBM148230(US8962630, 39)
Affinity DataIC50: 1.50E+4nMAssay Description:The assay was run under the conditions identical to that for CDK1/cyclin B except 0.25 nM CDK1/cyclin B was replaced with 0.3 nM CDK2/cyclin A. A 384...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2015
Entry Details
Go to US Patent

TargetCyclin-dependent kinase 2(Human)
Novartis

US Patent
LigandPNGBDBM148246(US8962630, 55)
Affinity DataIC50: 1.50E+4nMAssay Description:The assay was run under the conditions identical to that for CDK1/cyclin B except 0.25 nM CDK1/cyclin B was replaced with 0.3 nM CDK2/cyclin A. A 384...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2015
Entry Details
Go to US Patent

TargetCyclin-dependent kinase 2(Human)
Novartis

US Patent
LigandPNGBDBM148251(US8962630, 60)
Affinity DataIC50: 1.50E+4nMAssay Description:The assay was run under the conditions identical to that for CDK1/cyclin B except 0.25 nM CDK1/cyclin B was replaced with 0.3 nM CDK2/cyclin A. A 384...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2015
Entry Details
Go to US Patent

TargetCyclin-dependent kinase 2(Human)
Novartis

US Patent
LigandPNGBDBM148252(US8962630, 61)
Affinity DataIC50: 1.50E+4nMAssay Description:The assay was run under the conditions identical to that for CDK1/cyclin B except 0.25 nM CDK1/cyclin B was replaced with 0.3 nM CDK2/cyclin A. A 384...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2015
Entry Details
Go to US Patent

TargetCyclin-dependent kinase 2(Human)
Novartis

US Patent
LigandPNGBDBM148253(US8962630, 62)
Affinity DataIC50: 1.50E+4nMAssay Description:The assay was run under the conditions identical to that for CDK1/cyclin B except 0.25 nM CDK1/cyclin B was replaced with 0.3 nM CDK2/cyclin A. A 384...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2015
Entry Details
Go to US Patent

TargetCyclin-dependent kinase 2(Human)
Novartis

US Patent
LigandPNGBDBM148225(US8962630, 34)
Affinity DataIC50: 1.50E+4nMAssay Description:The assay was run under the conditions identical to that for CDK1/cyclin B except 0.25 nM CDK1/cyclin B was replaced with 0.3 nM CDK2/cyclin A. A 384...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2015
Entry Details
Go to US Patent

TargetCyclin-dependent kinase 2(Human)
Novartis

US Patent
LigandPNGBDBM148233(US8962630, 42)
Affinity DataIC50: 1.50E+4nMAssay Description:The assay was run under the conditions identical to that for CDK1/cyclin B except 0.25 nM CDK1/cyclin B was replaced with 0.3 nM CDK2/cyclin A. A 384...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2015
Entry Details
Go to US Patent

TargetCyclin-dependent kinase 2(Human)
Novartis

US Patent
LigandPNGBDBM148234(US8962630, 43)
Affinity DataIC50: 1.50E+4nMAssay Description:The assay was run under the conditions identical to that for CDK1/cyclin B except 0.25 nM CDK1/cyclin B was replaced with 0.3 nM CDK2/cyclin A. A 384...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2015
Entry Details
Go to US Patent

TargetCyclin-dependent kinase 2(Human)
Novartis

US Patent
LigandPNGBDBM148245(US8962630, 54)
Affinity DataIC50: 1.50E+4nMAssay Description:The assay was run under the conditions identical to that for CDK1/cyclin B except 0.25 nM CDK1/cyclin B was replaced with 0.3 nM CDK2/cyclin A. A 384...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2015
Entry Details
Go to US Patent

TargetCyclin-dependent kinase 2(Human)
Novartis

US Patent
LigandPNGBDBM148267(US8962630, 77)
Affinity DataIC50: 1.50E+4nMAssay Description:The assay was run under the conditions identical to that for CDK1/cyclin B except 0.25 nM CDK1/cyclin B was replaced with 0.3 nM CDK2/cyclin A. A 384...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2015
Entry Details
Go to US Patent

TargetCyclin-dependent kinase 2(Human)
Novartis

US Patent
LigandPNGBDBM148275(US8962630, 85)
Affinity DataIC50: 1.50E+4nMAssay Description:The assay was run under the conditions identical to that for CDK1/cyclin B except 0.25 nM CDK1/cyclin B was replaced with 0.3 nM CDK2/cyclin A. A 384...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2015
Entry Details
Go to US Patent

TargetCyclin-dependent kinase 2(Human)
Novartis

US Patent
LigandPNGBDBM148256(US8962630, 66)
Affinity DataIC50: 1.50E+4nMAssay Description:The assay was run under the conditions identical to that for CDK1/cyclin B except 0.25 nM CDK1/cyclin B was replaced with 0.3 nM CDK2/cyclin A. A 384...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2015
Entry Details
Go to US Patent

TargetCyclin-dependent kinase 2(Human)
Novartis

US Patent
LigandPNGBDBM148195(US8962630, 3)
Affinity DataIC50: 1.50E+4nMAssay Description:The assay was run under the conditions identical to that for CDK1/cyclin B except 0.25 nM CDK1/cyclin B was replaced with 0.3 nM CDK2/cyclin A. A 384...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2015
Entry Details
Go to US Patent

TargetCyclin-dependent kinase 2(Human)
Novartis

US Patent
LigandPNGBDBM148255(US8962630, 65)
Affinity DataIC50: 1.50E+4nMAssay Description:The assay was run under the conditions identical to that for CDK1/cyclin B except 0.25 nM CDK1/cyclin B was replaced with 0.3 nM CDK2/cyclin A. A 384...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2015
Entry Details
Go to US Patent

TargetCyclin-dependent kinase 2(Human)
Novartis

US Patent
LigandPNGBDBM148263(US8962630, 73)
Affinity DataIC50: 1.50E+4nMAssay Description:The assay was run under the conditions identical to that for CDK1/cyclin B except 0.25 nM CDK1/cyclin B was replaced with 0.3 nM CDK2/cyclin A. A 384...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2015
Entry Details
Go to US Patent

TargetCyclin-dependent kinase 2(Human)
Novartis

US Patent
LigandPNGBDBM148265(US8962630, 75)
Affinity DataIC50: 1.50E+4nMAssay Description:The assay was run under the conditions identical to that for CDK1/cyclin B except 0.25 nM CDK1/cyclin B was replaced with 0.3 nM CDK2/cyclin A. A 384...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2015
Entry Details
Go to US Patent

TargetCyclin-dependent kinase 2(Human)
Novartis

US Patent
LigandPNGBDBM148266(US8962630, 76)
Affinity DataIC50: 1.50E+4nMAssay Description:The assay was run under the conditions identical to that for CDK1/cyclin B except 0.25 nM CDK1/cyclin B was replaced with 0.3 nM CDK2/cyclin A. A 384...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2015
Entry Details
Go to US Patent

TargetCyclin-dependent kinase 2(Human)
Novartis

US Patent
LigandPNGBDBM148277(US8962630, 87)
Affinity DataIC50: 1.50E+4nMAssay Description:The assay was run under the conditions identical to that for CDK1/cyclin B except 0.25 nM CDK1/cyclin B was replaced with 0.3 nM CDK2/cyclin A. A 384...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2015
Entry Details
Go to US Patent

TargetCyclin-dependent kinase 2(Human)
Novartis

US Patent
LigandPNGBDBM148197(US8962630, 6)
Affinity DataIC50: 1.50E+4nMAssay Description:The assay was run under the conditions identical to that for CDK1/cyclin B except 0.25 nM CDK1/cyclin B was replaced with 0.3 nM CDK2/cyclin A. A 384...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2015
Entry Details
Go to US Patent

TargetCyclin-dependent kinase 2(Human)
Novartis

US Patent
LigandPNGBDBM148212(US8962630, 20)
Affinity DataIC50: 1.50E+4nMAssay Description:The assay was run under the conditions identical to that for CDK1/cyclin B except 0.25 nM CDK1/cyclin B was replaced with 0.3 nM CDK2/cyclin A. A 384...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2015
Entry Details
Go to US Patent

TargetCyclin-dependent kinase 2(Human)
Novartis

US Patent
LigandPNGBDBM148244(US8962630, 53)
Affinity DataIC50: 1.50E+4nMAssay Description:The assay was run under the conditions identical to that for CDK1/cyclin B except 0.25 nM CDK1/cyclin B was replaced with 0.3 nM CDK2/cyclin A. A 384...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2015
Entry Details
Go to US Patent

TargetCyclin-dependent kinase 2(Human)
Novartis

US Patent
LigandPNGBDBM148240(US8962630, 49)
Affinity DataIC50: 1.50E+4nMAssay Description:The assay was run under the conditions identical to that for CDK1/cyclin B except 0.25 nM CDK1/cyclin B was replaced with 0.3 nM CDK2/cyclin A. A 384...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2015
Entry Details
Go to US Patent

TargetCyclin-dependent kinase 2(Human)
Novartis

US Patent
LigandPNGBDBM148284(US8962630, 96)
Affinity DataIC50: 1.50E+4nMAssay Description:The assay was run under the conditions identical to that for CDK1/cyclin B except 0.25 nM CDK1/cyclin B was replaced with 0.3 nM CDK2/cyclin A. A 384...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2015
Entry Details
Go to US Patent

TargetCyclin-dependent kinase 2(Human)
Novartis

US Patent
LigandPNGBDBM148241(US8962630, 50)
Affinity DataIC50: 1.50E+4nMAssay Description:The assay was run under the conditions identical to that for CDK1/cyclin B except 0.25 nM CDK1/cyclin B was replaced with 0.3 nM CDK2/cyclin A. A 384...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2015
Entry Details
Go to US Patent

TargetCyclin-dependent kinase 2(Human)
Novartis

US Patent
LigandPNGBDBM148257(US8962630, 67)
Affinity DataIC50: 1.50E+4nMAssay Description:The assay was run under the conditions identical to that for CDK1/cyclin B except 0.25 nM CDK1/cyclin B was replaced with 0.3 nM CDK2/cyclin A. A 384...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2015
Entry Details
Go to US Patent

TargetCyclin-dependent kinase 2(Human)
Novartis

US Patent
LigandPNGBDBM148260(US8962630, 70)
Affinity DataIC50: 1.50E+4nMAssay Description:The assay was run under the conditions identical to that for CDK1/cyclin B except 0.25 nM CDK1/cyclin B was replaced with 0.3 nM CDK2/cyclin A. A 384...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2015
Entry Details
Go to US Patent

TargetCyclin-dependent kinase 2(Human)
Novartis

US Patent
LigandPNGBDBM148228(US8962630, 37)
Affinity DataIC50: 1.50E+4nMAssay Description:The assay was run under the conditions identical to that for CDK1/cyclin B except 0.25 nM CDK1/cyclin B was replaced with 0.3 nM CDK2/cyclin A. A 384...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2015
Entry Details
Go to US Patent

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