Compile Data Set for Download or QSAR
Report error Found 24 Enz. Inhib. hit(s) with all data for entry = 6666
TargetProstaglandin E2 receptor EP4 subtype(Human)
Merck Frosst Canada

US Patent
LigandChemical structure of BindingDB Monomer ID 144433BDBM144433(US8969394, 5)
Affinity DataKi:  0.470nM ΔG°:  -53.2kJ/molepH: 6.0 T: 2°CAssay Description:Transfected HEK 293(ebna) cells are maintained in culture, harvested and membranes are prepared by differential centrifugation, following lysis of th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2015
Entry Details
US Patent

TargetProstaglandin E2 receptor EP4 subtype(Human)
Merck Frosst Canada

US Patent
LigandChemical structure of BindingDB Monomer ID 50308131BDBM50308131(4-{1-[({2,5-Dimethyl-4-[4-(trifluoromethyl)benzyl]...)
Affinity DataKi:  0.5nM ΔG°:  -53.1kJ/molepH: 6.0 T: 2°CAssay Description:Transfected HEK 293(ebna) cells are maintained in culture, harvested and membranes are prepared by differential centrifugation, following lysis of th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2015
Entry Details
US Patent

TargetProstaglandin E2 receptor EP4 subtype(Human)
Merck Frosst Canada

US Patent
LigandChemical structure of BindingDB Monomer ID 144440BDBM144440(US8969394, 14)
Affinity DataKi:  0.600nM ΔG°:  -52.6kJ/molepH: 6.0 T: 2°CAssay Description:Transfected HEK 293(ebna) cells are maintained in culture, harvested and membranes are prepared by differential centrifugation, following lysis of th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2015
Entry Details
US Patent

TargetProstaglandin E2 receptor EP4 subtype(Human)
Merck Frosst Canada

US Patent
LigandChemical structure of BindingDB Monomer ID 144447BDBM144447(US8969394, 26)
Affinity DataKi:  0.700nM ΔG°:  -52.3kJ/molepH: 6.0 T: 2°CAssay Description:Transfected HEK 293(ebna) cells are maintained in culture, harvested and membranes are prepared by differential centrifugation, following lysis of th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2015
Entry Details
US Patent

TargetProstaglandin E2 receptor EP4 subtype(Human)
Merck Frosst Canada

US Patent
LigandChemical structure of BindingDB Monomer ID 144432BDBM144432(US8969394, 4)
Affinity DataKi:  0.710nM ΔG°:  -52.2kJ/molepH: 6.0 T: 2°CAssay Description:Transfected HEK 293(ebna) cells are maintained in culture, harvested and membranes are prepared by differential centrifugation, following lysis of th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2015
Entry Details
US Patent

TargetProstaglandin E2 receptor EP4 subtype(Human)
Merck Frosst Canada

US Patent
LigandChemical structure of BindingDB Monomer ID 50308130BDBM50308130(4-{1-[({2,5-Dimethyl-4-[3-(trifluoromethyl)benzyl]...)
Affinity DataKi:  0.800nM ΔG°:  -51.9kJ/molepH: 6.0 T: 2°CAssay Description:Transfected HEK 293(ebna) cells are maintained in culture, harvested and membranes are prepared by differential centrifugation, following lysis of th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2015
Entry Details
US Patent

TargetProstaglandin E2 receptor EP4 subtype(Human)
Merck Frosst Canada

US Patent
LigandChemical structure of BindingDB Monomer ID 144445BDBM144445(US8969394, 21)
Affinity DataKi:  0.800nM ΔG°:  -51.9kJ/molepH: 6.0 T: 2°CAssay Description:Transfected HEK 293(ebna) cells are maintained in culture, harvested and membranes are prepared by differential centrifugation, following lysis of th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2015
Entry Details
US Patent

TargetProstaglandin E2 receptor EP4 subtype(Human)
Merck Frosst Canada

US Patent
LigandChemical structure of BindingDB Monomer ID 50308134BDBM50308134(4-[({[2,5-Dichloro-4-(3-chlorobenzyl)-3-thienyl]ca...)
Affinity DataKi:  0.900nM ΔG°:  -51.6kJ/molepH: 6.0 T: 2°CAssay Description:Transfected HEK 293(ebna) cells are maintained in culture, harvested and membranes are prepared by differential centrifugation, following lysis of th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2015
Entry Details
US Patent

TargetProstaglandin E2 receptor EP4 subtype(Human)
Merck Frosst Canada

US Patent
LigandChemical structure of BindingDB Monomer ID 50308133BDBM50308133(4-[(1R)-1-({[2,5-Dichloro-4-(3-chlorobenzyl)-3-thi...)
Affinity DataKi:  0.900nM ΔG°:  -51.6kJ/molepH: 6.0 T: 2°CAssay Description:Transfected HEK 293(ebna) cells are maintained in culture, harvested and membranes are prepared by differential centrifugation, following lysis of th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2015
Entry Details
US Patent

TargetProstaglandin E2 receptor EP4 subtype(Human)
Merck Frosst Canada

US Patent
LigandChemical structure of BindingDB Monomer ID 50308125BDBM50308125(4-[(1S)-1-({[2,5-Dichloro-4-(3-chlorobenzyl)-3-thi...)
Affinity DataKi:  1.30nM ΔG°:  -50.7kJ/molepH: 6.0 T: 2°CAssay Description:Transfected HEK 293(ebna) cells are maintained in culture, harvested and membranes are prepared by differential centrifugation, following lysis of th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2015
Entry Details
US Patent

TargetProstaglandin E2 receptor EP4 subtype(Human)
Merck Frosst Canada

US Patent
LigandChemical structure of BindingDB Monomer ID 50308129BDBM50308129(4-{(1S)-1-[({2,5-Dimethyl-4-[4-(trifluoromethyl)be...)
Affinity DataKi:  1.40nM ΔG°:  -50.5kJ/molepH: 6.0 T: 2°CAssay Description:Transfected HEK 293(ebna) cells are maintained in culture, harvested and membranes are prepared by differential centrifugation, following lysis of th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2015
Entry Details
US Patent

TargetProstaglandin E2 receptor EP4 subtype(Human)
Merck Frosst Canada

US Patent
LigandChemical structure of BindingDB Monomer ID 144436BDBM144436(US8969394, 9)
Affinity DataKi:  1.80nM ΔG°:  -49.9kJ/molepH: 6.0 T: 2°CAssay Description:Transfected HEK 293(ebna) cells are maintained in culture, harvested and membranes are prepared by differential centrifugation, following lysis of th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2015
Entry Details
US Patent

TargetProstaglandin E2 receptor EP4 subtype(Human)
Merck Frosst Canada

US Patent
LigandChemical structure of BindingDB Monomer ID 50308127BDBM50308127(4-{(1S)-1-[({2,5-Dimethyl-4-[3-(trifluoromethyl)be...)
Affinity DataKi:  2.40nM ΔG°:  -49.2kJ/molepH: 6.0 T: 2°CAssay Description:Transfected HEK 293(ebna) cells are maintained in culture, harvested and membranes are prepared by differential centrifugation, following lysis of th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2015
Entry Details
US Patent

TargetProstaglandin E2 receptor EP4 subtype(Human)
Merck Frosst Canada

US Patent
LigandChemical structure of BindingDB Monomer ID 144431BDBM144431(US8969394, 2)
Affinity DataKi:  2.60nM ΔG°:  -49.0kJ/molepH: 6.0 T: 2°CAssay Description:Transfected HEK 293(ebna) cells are maintained in culture, harvested and membranes are prepared by differential centrifugation, following lysis of th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2015
Entry Details
US Patent

TargetProstaglandin E2 receptor EP4 subtype(Human)
Merck Frosst Canada

US Patent
LigandChemical structure of BindingDB Monomer ID 50308126BDBM50308126(4-[(1S)-1-({[4-(3-Chlorobenzyl)-2,5-dimethyl-3-thi...)
Affinity DataKi:  3.10nM ΔG°:  -48.6kJ/molepH: 6.0 T: 2°CAssay Description:Transfected HEK 293(ebna) cells are maintained in culture, harvested and membranes are prepared by differential centrifugation, following lysis of th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2015
Entry Details
US Patent

TargetProstaglandin E2 receptor EP4 subtype(Human)
Merck Frosst Canada

US Patent
LigandChemical structure of BindingDB Monomer ID 50308128BDBM50308128(4-[(1S)-1-({[4-(4-Chlorobenzyl)-2,5-dimethyl-3-thi...)
Affinity DataKi:  3.40nM ΔG°:  -48.3kJ/molepH: 6.0 T: 2°CAssay Description:Transfected HEK 293(ebna) cells are maintained in culture, harvested and membranes are prepared by differential centrifugation, following lysis of th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2015
Entry Details
US Patent

TargetProstaglandin E2 receptor EP4 subtype(Human)
Merck Frosst Canada

US Patent
LigandChemical structure of BindingDB Monomer ID 144430BDBM144430(US8969394, 1)
Affinity DataKi:  5.20nM ΔG°:  -47.3kJ/molepH: 6.0 T: 2°CAssay Description:Transfected HEK 293(ebna) cells are maintained in culture, harvested and membranes are prepared by differential centrifugation, following lysis of th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2015
Entry Details
US Patent

TargetProstaglandin E2 receptor EP4 subtype(Human)
Merck Frosst Canada

US Patent
LigandChemical structure of BindingDB Monomer ID 144437BDBM144437(US8969394, 10)
Affinity DataKi:  7.40nM ΔG°:  -46.4kJ/molepH: 6.0 T: 2°CAssay Description:Transfected HEK 293(ebna) cells are maintained in culture, harvested and membranes are prepared by differential centrifugation, following lysis of th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2015
Entry Details
US Patent

TargetProstaglandin E2 receptor EP4 subtype(Human)
Merck Frosst Canada

US Patent
LigandChemical structure of BindingDB Monomer ID 50308124BDBM50308124(4-[(1S)-1-({[4-(3-Chlorobenzyl)-3-thienyl]carbonyl...)
Affinity DataKi:  7.90nM ΔG°:  -46.2kJ/molepH: 6.0 T: 2°CAssay Description:Transfected HEK 293(ebna) cells are maintained in culture, harvested and membranes are prepared by differential centrifugation, following lysis of th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2015
Entry Details
US Patent

TargetProstaglandin E2 receptor EP4 subtype(Human)
Merck Frosst Canada

US Patent
LigandChemical structure of BindingDB Monomer ID 144446BDBM144446(US8969394, 25)
Affinity DataKi:  30nM ΔG°:  -42.9kJ/molepH: 6.0 T: 2°CAssay Description:Transfected HEK 293(ebna) cells are maintained in culture, harvested and membranes are prepared by differential centrifugation, following lysis of th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2015
Entry Details
US Patent

TargetProstaglandin E2 receptor EP4 subtype(Human)
Merck Frosst Canada

US Patent
LigandChemical structure of BindingDB Monomer ID 144435BDBM144435(US8969394, 8)
Affinity DataKi:  51nM ΔG°:  -41.6kJ/molepH: 6.0 T: 2°CAssay Description:Transfected HEK 293(ebna) cells are maintained in culture, harvested and membranes are prepared by differential centrifugation, following lysis of th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2015
Entry Details
US Patent

TargetProstaglandin E2 receptor EP4 subtype(Human)
Merck Frosst Canada

US Patent
LigandChemical structure of BindingDB Monomer ID 144434BDBM144434(US8969394, 6)
Affinity DataKi:  124nM ΔG°:  -39.4kJ/molepH: 6.0 T: 2°CAssay Description:Transfected HEK 293(ebna) cells are maintained in culture, harvested and membranes are prepared by differential centrifugation, following lysis of th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2015
Entry Details
US Patent

TargetProstaglandin E2 receptor EP4 subtype(Human)
Merck Frosst Canada

US Patent
LigandChemical structure of BindingDB Monomer ID 144444BDBM144444(US8969394, 19)
Affinity DataKi:  133nM ΔG°:  -39.2kJ/molepH: 6.0 T: 2°CAssay Description:Transfected HEK 293(ebna) cells are maintained in culture, harvested and membranes are prepared by differential centrifugation, following lysis of th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2015
Entry Details
US Patent

TargetProstaglandin E2 receptor EP4 subtype(Human)
Merck Frosst Canada

US Patent
LigandChemical structure of BindingDB Monomer ID 144443BDBM144443(US8969394, 18)
Affinity DataKi:  308nM ΔG°:  -37.2kJ/molepH: 6.0 T: 2°CAssay Description:Transfected HEK 293(ebna) cells are maintained in culture, harvested and membranes are prepared by differential centrifugation, following lysis of th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2015
Entry Details
US Patent