Compile Data Set for Download or QSAR
maximum 50k data
Report error Found 25 Enz. Inhib. hit(s) with all data for entry = 6742
TargetBeta-secretase 1(Human)
Vitae Pharmaceuticals

US Patent
LigandPNGBDBM150700(US8981112, 7 | US9526727, 7 | US9949975, Example 7)
Affinity DataIC50:  2nMpH: 4.4Assay Description:The inhibitory activity of compounds was assessed by a fluorescence quench assay of BACE1 activity using commercially available substrate HiLyte Fluo...More data for this Ligand-Target Pair
In DepthDetails US Patent


TargetBeta-secretase 1(Human)
Vitae Pharmaceuticals

US Patent
LigandPNGBDBM150705(US8981112, 12 | US9526727, 12 | US9949975, Example...)
Affinity DataIC50:  3nMpH: 4.4Assay Description:The inhibitory activity of compounds was assessed by a fluorescence quench assay of BACE1 activity using commercially available substrate HiLyte Fluo...More data for this Ligand-Target Pair
In DepthDetails US Patent


TargetBeta-secretase 1(Human)
Vitae Pharmaceuticals

US Patent
LigandPNGBDBM150704(US8981112, 11 | US9526727, 11 | US9949975, Example...)
Affinity DataIC50:  4nMpH: 4.4Assay Description:The inhibitory activity of compounds was assessed by a fluorescence quench assay of BACE1 activity using commercially available substrate HiLyte Fluo...More data for this Ligand-Target Pair
In DepthDetails US Patent


TargetBeta-secretase 1(Human)
Vitae Pharmaceuticals

US Patent
LigandPNGBDBM150717(US8981112, 24 | US9526727, 24 | US9949975, Example...)
Affinity DataIC50:  5nMpH: 4.4Assay Description:The inhibitory activity of compounds was assessed by a fluorescence quench assay of BACE1 activity using commercially available substrate HiLyte Fluo...More data for this Ligand-Target Pair
In DepthDetails US Patent


TargetBeta-secretase 1(Human)
Vitae Pharmaceuticals

US Patent
LigandPNGBDBM150697(US8981112, 4 | US9526727, 4)
Affinity DataIC50:  5nMpH: 4.4Assay Description:The inhibitory activity of compounds was assessed by a fluorescence quench assay of BACE1 activity using commercially available substrate HiLyte Fluo...More data for this Ligand-Target Pair
In DepthDetails US Patent


TargetBeta-secretase 1(Human)
Vitae Pharmaceuticals

US Patent
LigandPNGBDBM150714(US8981112, 21 | US9526727, 21 | US9949975, Example...)
Affinity DataIC50:  5nMpH: 4.4Assay Description:The inhibitory activity of compounds was assessed by a fluorescence quench assay of BACE1 activity using commercially available substrate HiLyte Fluo...More data for this Ligand-Target Pair
In DepthDetails US Patent


TargetBeta-secretase 1(Human)
Vitae Pharmaceuticals

US Patent
LigandPNGBDBM150707(US8981112, 14 | US9526727, 14 | US9949975, Example...)
Affinity DataIC50:  5nMpH: 4.4Assay Description:The inhibitory activity of compounds was assessed by a fluorescence quench assay of BACE1 activity using commercially available substrate HiLyte Fluo...More data for this Ligand-Target Pair
In DepthDetails US Patent


TargetBeta-secretase 1(Human)
Vitae Pharmaceuticals

US Patent
LigandPNGBDBM150701(US8981112, 8 | US9526727, 8 | US9949975, Example 8)
Affinity DataIC50:  5nMpH: 4.4Assay Description:The inhibitory activity of compounds was assessed by a fluorescence quench assay of BACE1 activity using commercially available substrate HiLyte Fluo...More data for this Ligand-Target Pair
In DepthDetails US Patent


TargetBeta-secretase 1(Human)
Vitae Pharmaceuticals

US Patent
LigandPNGBDBM150712(US8981112, 19 | US9526727, 19 | US9949975, Example...)
Affinity DataIC50:  6nMpH: 4.4Assay Description:The inhibitory activity of compounds was assessed by a fluorescence quench assay of BACE1 activity using commercially available substrate HiLyte Fluo...More data for this Ligand-Target Pair
In DepthDetails US Patent


TargetBeta-secretase 1(Human)
Vitae Pharmaceuticals

US Patent
LigandPNGBDBM150720(US8981112, 27 | US9526727, 27 | US9949975, Example...)
Affinity DataIC50:  6nMpH: 4.4Assay Description:The inhibitory activity of compounds was assessed by a fluorescence quench assay of BACE1 activity using commercially available substrate HiLyte Fluo...More data for this Ligand-Target Pair
In DepthDetails US Patent


TargetBeta-secretase 1(Human)
Vitae Pharmaceuticals

US Patent
LigandPNGBDBM150698(US8981112, 5)
Affinity DataIC50:  8nMpH: 4.4Assay Description:The inhibitory activity of compounds was assessed by a fluorescence quench assay of BACE1 activity using commercially available substrate HiLyte Fluo...More data for this Ligand-Target Pair
In DepthDetails US Patent


TargetBeta-secretase 1(Human)
Vitae Pharmaceuticals

US Patent
LigandPNGBDBM150715(US8981112, 22 | US9526727, 22 | US9949975, Example...)
Affinity DataIC50:  8nMpH: 4.4Assay Description:The inhibitory activity of compounds was assessed by a fluorescence quench assay of BACE1 activity using commercially available substrate HiLyte Fluo...More data for this Ligand-Target Pair
In DepthDetails US Patent


TargetBeta-secretase 1(Human)
Vitae Pharmaceuticals

US Patent
LigandPNGBDBM150695(US8981112, 2 | US9526727, 2 | US9949975, Example 2)
Affinity DataIC50:  8nMpH: 4.4Assay Description:The inhibitory activity of compounds was assessed by a fluorescence quench assay of BACE1 activity using commercially available substrate HiLyte Fluo...More data for this Ligand-Target Pair
In DepthDetails US Patent


TargetBeta-secretase 1(Human)
Vitae Pharmaceuticals

US Patent
LigandPNGBDBM150703(US8981112, 10 | US9526727, 10 | US9949975, Example...)
Affinity DataIC50:  9nMpH: 4.4Assay Description:The inhibitory activity of compounds was assessed by a fluorescence quench assay of BACE1 activity using commercially available substrate HiLyte Fluo...More data for this Ligand-Target Pair
In DepthDetails US Patent


TargetBeta-secretase 1(Human)
Vitae Pharmaceuticals

US Patent
LigandPNGBDBM150702(US8981112, 9 | US9526727, 9 | US9949975, Example 9)
Affinity DataIC50:  9nMpH: 4.4Assay Description:The inhibitory activity of compounds was assessed by a fluorescence quench assay of BACE1 activity using commercially available substrate HiLyte Fluo...More data for this Ligand-Target Pair
In DepthDetails US Patent


TargetBeta-secretase 1(Human)
Vitae Pharmaceuticals

US Patent
LigandPNGBDBM150706(US8981112, 13 | US9526727, 13 | US9949975, Example...)
Affinity DataIC50:  9nMpH: 4.4Assay Description:The inhibitory activity of compounds was assessed by a fluorescence quench assay of BACE1 activity using commercially available substrate HiLyte Fluo...More data for this Ligand-Target Pair
In DepthDetails US Patent


TargetBeta-secretase 1(Human)
Vitae Pharmaceuticals

US Patent
LigandPNGBDBM150719(US8981112, 26 | US9526727, 26 | US9949975, Example...)
Affinity DataIC50:  9nMpH: 4.4Assay Description:The inhibitory activity of compounds was assessed by a fluorescence quench assay of BACE1 activity using commercially available substrate HiLyte Fluo...More data for this Ligand-Target Pair
In DepthDetails US Patent


TargetBeta-secretase 1(Human)
Vitae Pharmaceuticals

US Patent
LigandPNGBDBM150711(US8981112, 18 | US9526727, 18 | US9949975, Example...)
Affinity DataIC50:  9nMpH: 4.4Assay Description:The inhibitory activity of compounds was assessed by a fluorescence quench assay of BACE1 activity using commercially available substrate HiLyte Fluo...More data for this Ligand-Target Pair
In DepthDetails US Patent


TargetBeta-secretase 1(Human)
Vitae Pharmaceuticals

US Patent
LigandPNGBDBM150696(US8981112, 3 | US9526727, 3 | US9949975, Example 3)
Affinity DataIC50:  10nMpH: 4.4Assay Description:The inhibitory activity of compounds was assessed by a fluorescence quench assay of BACE1 activity using commercially available substrate HiLyte Fluo...More data for this Ligand-Target Pair
In DepthDetails US Patent


TargetBeta-secretase 1(Human)
Vitae Pharmaceuticals

US Patent
LigandPNGBDBM150708(US8981112, 15 | US9526727, 15 | US9949975, Example...)
Affinity DataIC50:  11nMpH: 4.4Assay Description:The inhibitory activity of compounds was assessed by a fluorescence quench assay of BACE1 activity using commercially available substrate HiLyte Fluo...More data for this Ligand-Target Pair
In DepthDetails US Patent


TargetBeta-secretase 1(Human)
Vitae Pharmaceuticals

US Patent
LigandPNGBDBM150699(US8981112, 6 | US9526727, 6 | US9949975, Example 6)
Affinity DataIC50:  11nMpH: 4.4Assay Description:The inhibitory activity of compounds was assessed by a fluorescence quench assay of BACE1 activity using commercially available substrate HiLyte Fluo...More data for this Ligand-Target Pair
In DepthDetails US Patent


TargetBeta-secretase 1(Human)
Vitae Pharmaceuticals

US Patent
LigandPNGBDBM150694(US8981112, 1)
Affinity DataIC50:  11nMpH: 4.4Assay Description:The inhibitory activity of compounds was assessed by a fluorescence quench assay of BACE1 activity using commercially available substrate HiLyte Fluo...More data for this Ligand-Target Pair
In DepthDetails US Patent


TargetBeta-secretase 1(Human)
Vitae Pharmaceuticals

US Patent
LigandPNGBDBM150709(US8981112, 16 | US9526727, 16 | US9949975, Example...)
Affinity DataIC50:  11nMpH: 4.4Assay Description:The inhibitory activity of compounds was assessed by a fluorescence quench assay of BACE1 activity using commercially available substrate HiLyte Fluo...More data for this Ligand-Target Pair
In DepthDetails US Patent


TargetBeta-secretase 1(Human)
Vitae Pharmaceuticals

US Patent
LigandPNGBDBM150716(US8981112, 23 | US9526727, 23 | US9949975, Example...)
Affinity DataIC50:  12nMpH: 4.4Assay Description:The inhibitory activity of compounds was assessed by a fluorescence quench assay of BACE1 activity using commercially available substrate HiLyte Fluo...More data for this Ligand-Target Pair
In DepthDetails US Patent


TargetBeta-secretase 1(Human)
Vitae Pharmaceuticals

US Patent
LigandPNGBDBM150710(US8981112, 17 | US9526727, 17 | US9949975, Example...)
Affinity DataIC50:  14nMpH: 4.4Assay Description:The inhibitory activity of compounds was assessed by a fluorescence quench assay of BACE1 activity using commercially available substrate HiLyte Fluo...More data for this Ligand-Target Pair
In DepthDetails US Patent