Compile Data Set for Download or QSAR
Report error Found 75 Enz. Inhib. hit(s) with all data for entry = 6757
TargetRAC-alpha serine/threonine-protein kinase(Human)
Bayer Intellectual Property

US Patent
LigandChemical structure of BindingDB Monomer ID 151095BDBM151095(US8987273, 4-2)
Affinity DataIC50: 4nMpH: 7.5 T: 2°CAssay Description:Akt1 inhibitory activity of compounds of the present invention was quantified employing the Akt1 TR-FRET assay as described in the following paragrap...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2015
Entry Details
US Patent

TargetRAC-alpha serine/threonine-protein kinase(Human)
Bayer Intellectual Property

US Patent
LigandChemical structure of BindingDB Monomer ID 151092BDBM151092(US8987273, 3-0)
Affinity DataIC50: 5nMpH: 7.5 T: 2°CAssay Description:Akt1 inhibitory activity of compounds of the present invention was quantified employing the Akt1 TR-FRET assay as described in the following paragrap...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2015
Entry Details
US Patent

TargetRAC-alpha serine/threonine-protein kinase(Human)
Bayer Intellectual Property

US Patent
LigandChemical structure of BindingDB Monomer ID 151111BDBM151111(US8987273, 4-18)
Affinity DataIC50: 5nMpH: 7.5 T: 2°CAssay Description:Akt1 inhibitory activity of compounds of the present invention was quantified employing the Akt1 TR-FRET assay as described in the following paragrap...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2015
Entry Details
US Patent

TargetRAC-alpha serine/threonine-protein kinase(Human)
Bayer Intellectual Property

US Patent
LigandChemical structure of BindingDB Monomer ID 151098BDBM151098(US8987273, 4-5)
Affinity DataIC50: 6nMpH: 7.5 T: 2°CAssay Description:Akt1 inhibitory activity of compounds of the present invention was quantified employing the Akt1 TR-FRET assay as described in the following paragrap...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2015
Entry Details
US Patent

TargetRAC-alpha serine/threonine-protein kinase(Human)
Bayer Intellectual Property

US Patent
LigandChemical structure of BindingDB Monomer ID 151110BDBM151110(US8987273, 4-17)
Affinity DataIC50: 7nMpH: 7.5 T: 2°CAssay Description:Akt1 inhibitory activity of compounds of the present invention was quantified employing the Akt1 TR-FRET assay as described in the following paragrap...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2015
Entry Details
US Patent

TargetRAC-alpha serine/threonine-protein kinase(Human)
Bayer Intellectual Property

US Patent
LigandChemical structure of BindingDB Monomer ID 151105BDBM151105(US8987273, 4-12)
Affinity DataIC50: 9nMpH: 7.5 T: 2°CAssay Description:Akt1 inhibitory activity of compounds of the present invention was quantified employing the Akt1 TR-FRET assay as described in the following paragrap...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2015
Entry Details
US Patent

TargetRAC-alpha serine/threonine-protein kinase(Human)
Bayer Intellectual Property

US Patent
LigandChemical structure of BindingDB Monomer ID 151102BDBM151102(US8987273, 4-9)
Affinity DataIC50: 9nMpH: 7.5 T: 2°CAssay Description:Akt1 inhibitory activity of compounds of the present invention was quantified employing the Akt1 TR-FRET assay as described in the following paragrap...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2015
Entry Details
US Patent

TargetRAC-alpha serine/threonine-protein kinase(Human)
Bayer Intellectual Property

US Patent
LigandChemical structure of BindingDB Monomer ID 151108BDBM151108(US8987273, 4-15)
Affinity DataIC50: 11nMpH: 7.5 T: 2°CAssay Description:Akt1 inhibitory activity of compounds of the present invention was quantified employing the Akt1 TR-FRET assay as described in the following paragrap...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2015
Entry Details
US Patent

TargetRAC-alpha serine/threonine-protein kinase(Human)
Bayer Intellectual Property

US Patent
LigandChemical structure of BindingDB Monomer ID 151109BDBM151109(US8987273, 4-16)
Affinity DataIC50: 11nMpH: 7.5 T: 2°CAssay Description:Akt1 inhibitory activity of compounds of the present invention was quantified employing the Akt1 TR-FRET assay as described in the following paragrap...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2015
Entry Details
US Patent

TargetRAC-alpha serine/threonine-protein kinase(Human)
Bayer Intellectual Property

US Patent
LigandChemical structure of BindingDB Monomer ID 151104BDBM151104(US8987273, 4-11)
Affinity DataIC50: 13nMpH: 7.5 T: 2°CAssay Description:Akt1 inhibitory activity of compounds of the present invention was quantified employing the Akt1 TR-FRET assay as described in the following paragrap...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2015
Entry Details
US Patent

TargetRAC-alpha serine/threonine-protein kinase(Human)
Bayer Intellectual Property

US Patent
LigandChemical structure of BindingDB Monomer ID 151107BDBM151107(US8987273, 4-14)
Affinity DataIC50: 19nMpH: 7.5 T: 2°CAssay Description:Akt1 inhibitory activity of compounds of the present invention was quantified employing the Akt1 TR-FRET assay as described in the following paragrap...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2015
Entry Details
US Patent

TargetRAC-alpha serine/threonine-protein kinase(Human)
Bayer Intellectual Property

US Patent
LigandChemical structure of BindingDB Monomer ID 151099BDBM151099(US8987273, 4-6)
Affinity DataIC50: 19nMpH: 7.5 T: 2°CAssay Description:Akt1 inhibitory activity of compounds of the present invention was quantified employing the Akt1 TR-FRET assay as described in the following paragrap...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2015
Entry Details
US Patent

TargetRAC-beta serine/threonine-protein kinase(Human)
Bayer Intellectual Property

US Patent
LigandChemical structure of BindingDB Monomer ID 151109BDBM151109(US8987273, 4-16)
Affinity DataIC50: 22nMpH: 7.5 T: 2°CAssay Description:Akt2 inhibitory activity of compounds of the present invention was quantified employing the Akt2 TR-FRET assay as described in the following paragrap...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2015
Entry Details
US Patent

TargetRAC-alpha serine/threonine-protein kinase(Human)
Bayer Intellectual Property

US Patent
LigandChemical structure of BindingDB Monomer ID 151103BDBM151103(US8987273, 4-10)
Affinity DataIC50: 27nMpH: 7.5 T: 2°CAssay Description:Akt1 inhibitory activity of compounds of the present invention was quantified employing the Akt1 TR-FRET assay as described in the following paragrap...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2015
Entry Details
US Patent

TargetRAC-alpha serine/threonine-protein kinase(Human)
Bayer Intellectual Property

US Patent
LigandChemical structure of BindingDB Monomer ID 151096BDBM151096(US8987273, 4-3)
Affinity DataIC50: 36nMpH: 7.5 T: 2°CAssay Description:Akt1 inhibitory activity of compounds of the present invention was quantified employing the Akt1 TR-FRET assay as described in the following paragrap...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2015
Entry Details
US Patent

TargetRAC-beta serine/threonine-protein kinase(Human)
Bayer Intellectual Property

US Patent
LigandChemical structure of BindingDB Monomer ID 151098BDBM151098(US8987273, 4-5)
Affinity DataIC50: 37nMpH: 7.5 T: 2°CAssay Description:Akt2 inhibitory activity of compounds of the present invention was quantified employing the Akt2 TR-FRET assay as described in the following paragrap...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2015
Entry Details
US Patent

TargetRAC-alpha serine/threonine-protein kinase(Human)
Bayer Intellectual Property

US Patent
LigandChemical structure of BindingDB Monomer ID 151121BDBM151121(US8987273, 8-0)
Affinity DataIC50: 38nMpH: 7.5 T: 2°CAssay Description:Akt1 inhibitory activity of compounds of the present invention was quantified employing the Akt1 TR-FRET assay as described in the following paragrap...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2015
Entry Details
US Patent

TargetRAC-beta serine/threonine-protein kinase(Human)
Bayer Intellectual Property

US Patent
LigandChemical structure of BindingDB Monomer ID 151119BDBM151119(US8987273, 6-0)
Affinity DataIC50: 41nMpH: 7.5 T: 2°CAssay Description:Akt2 inhibitory activity of compounds of the present invention was quantified employing the Akt2 TR-FRET assay as described in the following paragrap...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2015
Entry Details
US Patent

TargetRAC-alpha serine/threonine-protein kinase(Human)
Bayer Intellectual Property

US Patent
LigandChemical structure of BindingDB Monomer ID 151122BDBM151122(US8987273, 9-0)
Affinity DataIC50: 44nMpH: 7.5 T: 2°CAssay Description:Akt1 inhibitory activity of compounds of the present invention was quantified employing the Akt1 TR-FRET assay as described in the following paragrap...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2015
Entry Details
US Patent

TargetRAC-alpha serine/threonine-protein kinase(Human)
Bayer Intellectual Property

US Patent
LigandChemical structure of BindingDB Monomer ID 151097BDBM151097(US8987273, 4-4)
Affinity DataIC50: 44nMpH: 7.5 T: 2°CAssay Description:Akt1 inhibitory activity of compounds of the present invention was quantified employing the Akt1 TR-FRET assay as described in the following paragrap...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2015
Entry Details
US Patent

TargetRAC-beta serine/threonine-protein kinase(Human)
Bayer Intellectual Property

US Patent
LigandChemical structure of BindingDB Monomer ID 151111BDBM151111(US8987273, 4-18)
Affinity DataIC50: 46nMpH: 7.5 T: 2°CAssay Description:Akt2 inhibitory activity of compounds of the present invention was quantified employing the Akt2 TR-FRET assay as described in the following paragrap...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2015
Entry Details
US Patent

TargetRAC-alpha serine/threonine-protein kinase(Human)
Bayer Intellectual Property

US Patent
LigandChemical structure of BindingDB Monomer ID 151100BDBM151100(US8987273, 4-7)
Affinity DataIC50: 47nMpH: 7.5 T: 2°CAssay Description:Akt1 inhibitory activity of compounds of the present invention was quantified employing the Akt1 TR-FRET assay as described in the following paragrap...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2015
Entry Details
US Patent

TargetRAC-beta serine/threonine-protein kinase(Human)
Bayer Intellectual Property

US Patent
LigandChemical structure of BindingDB Monomer ID 151095BDBM151095(US8987273, 4-2)
Affinity DataIC50: 58nMpH: 7.5 T: 2°CAssay Description:Akt2 inhibitory activity of compounds of the present invention was quantified employing the Akt2 TR-FRET assay as described in the following paragrap...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2015
Entry Details
US Patent

TargetRAC-beta serine/threonine-protein kinase(Human)
Bayer Intellectual Property

US Patent
LigandChemical structure of BindingDB Monomer ID 151105BDBM151105(US8987273, 4-12)
Affinity DataIC50: 67nMpH: 7.5 T: 2°CAssay Description:Akt2 inhibitory activity of compounds of the present invention was quantified employing the Akt2 TR-FRET assay as described in the following paragrap...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2015
Entry Details
US Patent

TargetRAC-beta serine/threonine-protein kinase(Human)
Bayer Intellectual Property

US Patent
LigandChemical structure of BindingDB Monomer ID 151104BDBM151104(US8987273, 4-11)
Affinity DataIC50: 68nMpH: 7.5 T: 2°CAssay Description:Akt2 inhibitory activity of compounds of the present invention was quantified employing the Akt2 TR-FRET assay as described in the following paragrap...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2015
Entry Details
US Patent

TargetRAC-alpha serine/threonine-protein kinase(Human)
Bayer Intellectual Property

US Patent
LigandChemical structure of BindingDB Monomer ID 151119BDBM151119(US8987273, 6-0)
Affinity DataIC50: 68nMpH: 7.5 T: 2°CAssay Description:Akt1 inhibitory activity of compounds of the present invention was quantified employing the Akt1 TR-FRET assay as described in the following paragrap...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2015
Entry Details
US Patent

TargetRAC-beta serine/threonine-protein kinase(Human)
Bayer Intellectual Property

US Patent
LigandChemical structure of BindingDB Monomer ID 151108BDBM151108(US8987273, 4-15)
Affinity DataIC50: 70nMpH: 7.5 T: 2°CAssay Description:Akt2 inhibitory activity of compounds of the present invention was quantified employing the Akt2 TR-FRET assay as described in the following paragrap...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2015
Entry Details
US Patent

TargetRAC-alpha serine/threonine-protein kinase(Human)
Bayer Intellectual Property

US Patent
LigandChemical structure of BindingDB Monomer ID 151101BDBM151101(US8987273, 4-8)
Affinity DataIC50: 74nMpH: 7.5 T: 2°CAssay Description:Akt1 inhibitory activity of compounds of the present invention was quantified employing the Akt1 TR-FRET assay as described in the following paragrap...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2015
Entry Details
US Patent

TargetRAC-beta serine/threonine-protein kinase(Human)
Bayer Intellectual Property

US Patent
LigandChemical structure of BindingDB Monomer ID 151096BDBM151096(US8987273, 4-3)
Affinity DataIC50: 81nMpH: 7.5 T: 2°CAssay Description:Akt2 inhibitory activity of compounds of the present invention was quantified employing the Akt2 TR-FRET assay as described in the following paragrap...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2015
Entry Details
US Patent

TargetRAC-beta serine/threonine-protein kinase(Human)
Bayer Intellectual Property

US Patent
LigandChemical structure of BindingDB Monomer ID 151092BDBM151092(US8987273, 3-0)
Affinity DataIC50: 82nMpH: 7.5 T: 2°CAssay Description:Akt2 inhibitory activity of compounds of the present invention was quantified employing the Akt2 TR-FRET assay as described in the following paragrap...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2015
Entry Details
US Patent

TargetRAC-beta serine/threonine-protein kinase(Human)
Bayer Intellectual Property

US Patent
LigandChemical structure of BindingDB Monomer ID 151102BDBM151102(US8987273, 4-9)
Affinity DataIC50: 92nMpH: 7.5 T: 2°CAssay Description:Akt2 inhibitory activity of compounds of the present invention was quantified employing the Akt2 TR-FRET assay as described in the following paragrap...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2015
Entry Details
US Patent

TargetRAC-alpha serine/threonine-protein kinase(Human)
Bayer Intellectual Property

US Patent
LigandChemical structure of BindingDB Monomer ID 151120BDBM151120(US8987273, 7-0)
Affinity DataIC50: 99nMpH: 7.5 T: 2°CAssay Description:Akt1 inhibitory activity of compounds of the present invention was quantified employing the Akt1 TR-FRET assay as described in the following paragrap...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2015
Entry Details
US Patent

TargetRAC-beta serine/threonine-protein kinase(Human)
Bayer Intellectual Property

US Patent
LigandChemical structure of BindingDB Monomer ID 151120BDBM151120(US8987273, 7-0)
Affinity DataIC50: 106nMpH: 7.5 T: 2°CAssay Description:Akt2 inhibitory activity of compounds of the present invention was quantified employing the Akt2 TR-FRET assay as described in the following paragrap...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2015
Entry Details
US Patent

TargetRAC-alpha serine/threonine-protein kinase(Human)
Bayer Intellectual Property

US Patent
LigandChemical structure of BindingDB Monomer ID 151093BDBM151093(US8987273, 4-0)
Affinity DataIC50: 110nMpH: 7.5 T: 2°CAssay Description:Akt1 inhibitory activity of compounds of the present invention was quantified employing the Akt1 TR-FRET assay as described in the following paragrap...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2015
Entry Details
US Patent

TargetRAC-beta serine/threonine-protein kinase(Human)
Bayer Intellectual Property

US Patent
LigandChemical structure of BindingDB Monomer ID 151110BDBM151110(US8987273, 4-17)
Affinity DataIC50: 110nMpH: 7.5 T: 2°CAssay Description:Akt2 inhibitory activity of compounds of the present invention was quantified employing the Akt2 TR-FRET assay as described in the following paragrap...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2015
Entry Details
US Patent

TargetRAC-beta serine/threonine-protein kinase(Human)
Bayer Intellectual Property

US Patent
LigandChemical structure of BindingDB Monomer ID 151107BDBM151107(US8987273, 4-14)
Affinity DataIC50: 115nMpH: 7.5 T: 2°CAssay Description:Akt2 inhibitory activity of compounds of the present invention was quantified employing the Akt2 TR-FRET assay as described in the following paragrap...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2015
Entry Details
US Patent

TargetRAC-beta serine/threonine-protein kinase(Human)
Bayer Intellectual Property

US Patent
LigandChemical structure of BindingDB Monomer ID 151103BDBM151103(US8987273, 4-10)
Affinity DataIC50: 118nMpH: 7.5 T: 2°CAssay Description:Akt2 inhibitory activity of compounds of the present invention was quantified employing the Akt2 TR-FRET assay as described in the following paragrap...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2015
Entry Details
US Patent

TargetRAC-beta serine/threonine-protein kinase(Human)
Bayer Intellectual Property

US Patent
LigandChemical structure of BindingDB Monomer ID 151099BDBM151099(US8987273, 4-6)
Affinity DataIC50: 123nMpH: 7.5 T: 2°CAssay Description:Akt2 inhibitory activity of compounds of the present invention was quantified employing the Akt2 TR-FRET assay as described in the following paragrap...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2015
Entry Details
US Patent

TargetRAC-alpha serine/threonine-protein kinase(Human)
Bayer Intellectual Property

US Patent
LigandChemical structure of BindingDB Monomer ID 151094BDBM151094(US8987273, 4-1)
Affinity DataIC50: 129nMpH: 7.5 T: 2°CAssay Description:Akt1 inhibitory activity of compounds of the present invention was quantified employing the Akt1 TR-FRET assay as described in the following paragrap...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2015
Entry Details
US Patent

TargetRAC-beta serine/threonine-protein kinase(Human)
Bayer Intellectual Property

US Patent
LigandChemical structure of BindingDB Monomer ID 151094BDBM151094(US8987273, 4-1)
Affinity DataIC50: 136nMpH: 7.5 T: 2°CAssay Description:Akt2 inhibitory activity of compounds of the present invention was quantified employing the Akt2 TR-FRET assay as described in the following paragrap...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2015
Entry Details
US Patent

TargetRAC-alpha serine/threonine-protein kinase(Human)
Bayer Intellectual Property

US Patent
LigandChemical structure of BindingDB Monomer ID 151106BDBM151106(US8987273, 4-13)
Affinity DataIC50: 146nMpH: 7.5 T: 2°CAssay Description:Akt1 inhibitory activity of compounds of the present invention was quantified employing the Akt1 TR-FRET assay as described in the following paragrap...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2015
Entry Details
US Patent

TargetRAC-beta serine/threonine-protein kinase(Human)
Bayer Intellectual Property

US Patent
LigandChemical structure of BindingDB Monomer ID 151100BDBM151100(US8987273, 4-7)
Affinity DataIC50: 151nMpH: 7.5 T: 2°CAssay Description:Akt2 inhibitory activity of compounds of the present invention was quantified employing the Akt2 TR-FRET assay as described in the following paragrap...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2015
Entry Details
US Patent

TargetRAC-beta serine/threonine-protein kinase(Human)
Bayer Intellectual Property

US Patent
LigandChemical structure of BindingDB Monomer ID 151121BDBM151121(US8987273, 8-0)
Affinity DataIC50: 222nMpH: 7.5 T: 2°CAssay Description:Akt2 inhibitory activity of compounds of the present invention was quantified employing the Akt2 TR-FRET assay as described in the following paragrap...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2015
Entry Details
US Patent

TargetRAC-alpha serine/threonine-protein kinase(Human)
Bayer Intellectual Property

US Patent
LigandChemical structure of BindingDB Monomer ID 50384861BDBM50384861(CHEMBL2035019)
Affinity DataIC50: 246nMpH: 7.5 T: 2°CAssay Description:Akt1 inhibitory activity of compounds of the present invention was quantified employing the Akt1 TR-FRET assay as described in the following paragrap...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2015
Entry Details
US Patent

TargetRAC-beta serine/threonine-protein kinase(Human)
Bayer Intellectual Property

US Patent
LigandChemical structure of BindingDB Monomer ID 151101BDBM151101(US8987273, 4-8)
Affinity DataIC50: 264nMpH: 7.5 T: 2°CAssay Description:Akt2 inhibitory activity of compounds of the present invention was quantified employing the Akt2 TR-FRET assay as described in the following paragrap...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2015
Entry Details
US Patent

TargetRAC-beta serine/threonine-protein kinase(Human)
Bayer Intellectual Property

US Patent
LigandChemical structure of BindingDB Monomer ID 151097BDBM151097(US8987273, 4-4)
Affinity DataIC50: 277nMpH: 7.5 T: 2°CAssay Description:Akt2 inhibitory activity of compounds of the present invention was quantified employing the Akt2 TR-FRET assay as described in the following paragrap...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2015
Entry Details
US Patent

TargetRAC-beta serine/threonine-protein kinase(Human)
Bayer Intellectual Property

US Patent
LigandChemical structure of BindingDB Monomer ID 151093BDBM151093(US8987273, 4-0)
Affinity DataIC50: 278nMpH: 7.5 T: 2°CAssay Description:Akt2 inhibitory activity of compounds of the present invention was quantified employing the Akt2 TR-FRET assay as described in the following paragrap...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2015
Entry Details
US Patent

TargetRAC-beta serine/threonine-protein kinase(Human)
Bayer Intellectual Property

US Patent
LigandChemical structure of BindingDB Monomer ID 151122BDBM151122(US8987273, 9-0)
Affinity DataIC50: 326nMpH: 7.5 T: 2°CAssay Description:Akt2 inhibitory activity of compounds of the present invention was quantified employing the Akt2 TR-FRET assay as described in the following paragrap...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2015
Entry Details
US Patent

TargetRAC-beta serine/threonine-protein kinase(Human)
Bayer Intellectual Property

US Patent
LigandChemical structure of BindingDB Monomer ID 151106BDBM151106(US8987273, 4-13)
Affinity DataIC50: 431nMpH: 7.5 T: 2°CAssay Description:Akt2 inhibitory activity of compounds of the present invention was quantified employing the Akt2 TR-FRET assay as described in the following paragrap...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2015
Entry Details
US Patent

TargetRAC-alpha serine/threonine-protein kinase(Human)
Bayer Intellectual Property

US Patent
LigandChemical structure of BindingDB Monomer ID 151091BDBM151091(US8987273, 2-0)
Affinity DataIC50: 441nMpH: 7.5 T: 2°CAssay Description:Akt1 inhibitory activity of compounds of the present invention was quantified employing the Akt1 TR-FRET assay as described in the following paragrap...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2015
Entry Details
US Patent

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