Compile Data Set for Download or QSAR
Report error Found 19 Enz. Inhib. hit(s) with all data for entry = 6840
TargetBeta-secretase 1(Human)
Shionogi

US Patent
LigandChemical structure of BindingDB Monomer ID 153625BDBM153625(US8999980, I-2)
Affinity DataIC50: 27nMpH: 5.0 T: 2°CAssay Description:48.5 .mu.L of substrate peptide solution (Biotin-XSEVNLDAEFRHDSGC-Eu: X=.epsilon.-amino-n-capronic acid, Eu=Europium cryptate) was added to each well...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2015
Entry Details
US Patent

TargetBeta-secretase 1(Human)
Shionogi

US Patent
LigandChemical structure of BindingDB Monomer ID 50432606BDBM50432606(CHEMBL2347206 | US8999980, I-53)
Affinity DataIC50: 46nMpH: 5.0 T: 2°CAssay Description:48.5 .mu.L of substrate peptide solution (Biotin-XSEVNLDAEFRHDSGC-Eu: X=.epsilon.-amino-n-capronic acid, Eu=Europium cryptate) was added to each well...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2015
Entry Details
US Patent
PDB3D3D Structure (crystal)
TargetBeta-secretase 1(Human)
Shionogi

US Patent
LigandChemical structure of BindingDB Monomer ID 153624BDBM153624(US8999980, I-1)
Affinity DataIC50: 47.3nMpH: 5.0 T: 2°CAssay Description:48.5 .mu.L of substrate peptide solution (Biotin-XSEVNLDAEFRHDSGC-Eu: X=.epsilon.-amino-n-capronic acid, Eu=Europium cryptate) was added to each well...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2015
Entry Details
US Patent

TargetBeta-secretase 1(Human)
Shionogi

US Patent
LigandChemical structure of BindingDB Monomer ID 50432609BDBM50432609(CHEMBL2347203 | US8999980, I-6)
Affinity DataIC50: 54nMpH: 5.0 T: 2°CAssay Description:48.5 .mu.L of substrate peptide solution (Biotin-XSEVNLDAEFRHDSGC-Eu: X=.epsilon.-amino-n-capronic acid, Eu=Europium cryptate) was added to each well...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2015
Entry Details
US Patent
PDB3D3D Structure (crystal)
TargetBeta-secretase 1(Human)
Shionogi

US Patent
LigandChemical structure of BindingDB Monomer ID 153632BDBM153632(US8999980, I-54)
Affinity DataIC50: 97nMpH: 5.0 T: 2°CAssay Description:48.5 .mu.L of substrate peptide solution (Biotin-XSEVNLDAEFRHDSGC-Eu: X=.epsilon.-amino-n-capronic acid, Eu=Europium cryptate) was added to each well...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2015
Entry Details
US Patent

TargetBeta-secretase 1(Human)
Shionogi

US Patent
LigandChemical structure of BindingDB Monomer ID 153633BDBM153633(US8999980, I-55)
Affinity DataIC50: 3.00E+4nMpH: 5.0 T: 2°CAssay Description:48.5 .mu.L of substrate peptide solution (Biotin-XSEVNLDAEFRHDSGC-Eu: X=.epsilon.-amino-n-capronic acid, Eu=Europium cryptate) was added to each well...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2015
Entry Details
US Patent

TargetBeta-secretase 1(Human)
Shionogi

US Patent
LigandChemical structure of BindingDB Monomer ID 153634BDBM153634(US8999980, I-56)
Affinity DataIC50: 3.00E+4nMpH: 5.0 T: 2°CAssay Description:48.5 .mu.L of substrate peptide solution (Biotin-XSEVNLDAEFRHDSGC-Eu: X=.epsilon.-amino-n-capronic acid, Eu=Europium cryptate) was added to each well...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2015
Entry Details
US Patent

TargetBeta-secretase 1(Human)
Shionogi

US Patent
LigandChemical structure of BindingDB Monomer ID 153635BDBM153635(US8999980, I-57)
Affinity DataIC50: 3.00E+4nMpH: 5.0 T: 2°CAssay Description:48.5 .mu.L of substrate peptide solution (Biotin-XSEVNLDAEFRHDSGC-Eu: X=.epsilon.-amino-n-capronic acid, Eu=Europium cryptate) was added to each well...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2015
Entry Details
US Patent

TargetBeta-secretase 1(Human)
Shionogi

US Patent
LigandChemical structure of BindingDB Monomer ID 153636BDBM153636(US8999980, I-58)
Affinity DataIC50: 3.00E+4nMpH: 5.0 T: 2°CAssay Description:48.5 .mu.L of substrate peptide solution (Biotin-XSEVNLDAEFRHDSGC-Eu: X=.epsilon.-amino-n-capronic acid, Eu=Europium cryptate) was added to each well...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2015
Entry Details
US Patent

TargetBeta-secretase 1(Human)
Shionogi

US Patent
LigandChemical structure of BindingDB Monomer ID 50432599BDBM50432599(CHEMBL2347209 | US8999980, I-8)
Affinity DataIC50: 3.00E+4nMpH: 5.0 T: 2°CAssay Description:48.5 .mu.L of substrate peptide solution (Biotin-XSEVNLDAEFRHDSGC-Eu: X=.epsilon.-amino-n-capronic acid, Eu=Europium cryptate) was added to each well...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2015
Entry Details
US Patent

TargetBeta-secretase 1(Human)
Shionogi

US Patent
LigandChemical structure of BindingDB Monomer ID 50436849BDBM50436849(CHEMBL2403768 | US8999980, I-9)
Affinity DataIC50: 3.00E+4nMpH: 5.0 T: 2°CAssay Description:48.5 .mu.L of substrate peptide solution (Biotin-XSEVNLDAEFRHDSGC-Eu: X=.epsilon.-amino-n-capronic acid, Eu=Europium cryptate) was added to each well...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2015
Entry Details
US Patent

TargetBeta-secretase 1(Human)
Shionogi

US Patent
LigandChemical structure of BindingDB Monomer ID 153630BDBM153630(US8999980, I-10)
Affinity DataIC50: 3.00E+4nMpH: 5.0 T: 2°CAssay Description:48.5 .mu.L of substrate peptide solution (Biotin-XSEVNLDAEFRHDSGC-Eu: X=.epsilon.-amino-n-capronic acid, Eu=Europium cryptate) was added to each well...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2015
Entry Details
US Patent

TargetBeta-secretase 1(Human)
Shionogi

US Patent
LigandChemical structure of BindingDB Monomer ID 153631BDBM153631(US8999980, I-11)
Affinity DataIC50: 3.00E+4nMpH: 5.0 T: 2°CAssay Description:48.5 .mu.L of substrate peptide solution (Biotin-XSEVNLDAEFRHDSGC-Eu: X=.epsilon.-amino-n-capronic acid, Eu=Europium cryptate) was added to each well...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2015
Entry Details
US Patent

TargetBeta-secretase 1(Human)
Shionogi

US Patent
LigandChemical structure of BindingDB Monomer ID 153637BDBM153637(US8999980, I-59)
Affinity DataIC50: 3.00E+4nMpH: 5.0 T: 2°CAssay Description:48.5 .mu.L of substrate peptide solution (Biotin-XSEVNLDAEFRHDSGC-Eu: X=.epsilon.-amino-n-capronic acid, Eu=Europium cryptate) was added to each well...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2015
Entry Details
US Patent

TargetBeta-secretase 1(Human)
Shionogi

US Patent
LigandChemical structure of BindingDB Monomer ID 153638BDBM153638(US8999980, I-60)
Affinity DataIC50: 3.00E+4nMpH: 5.0 T: 2°CAssay Description:48.5 .mu.L of substrate peptide solution (Biotin-XSEVNLDAEFRHDSGC-Eu: X=.epsilon.-amino-n-capronic acid, Eu=Europium cryptate) was added to each well...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2015
Entry Details
US Patent

TargetBeta-secretase 1(Human)
Shionogi

US Patent
LigandChemical structure of BindingDB Monomer ID 153626BDBM153626(US8999980, I-3)
Affinity DataIC50: 3.00E+4nMpH: 5.0 T: 2°CAssay Description:48.5 .mu.L of substrate peptide solution (Biotin-XSEVNLDAEFRHDSGC-Eu: X=.epsilon.-amino-n-capronic acid, Eu=Europium cryptate) was added to each well...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2015
Entry Details
US Patent

TargetBeta-secretase 1(Human)
Shionogi

US Patent
LigandChemical structure of BindingDB Monomer ID 153627BDBM153627(US8999980, I-4)
Affinity DataIC50: 3.00E+4nMpH: 5.0 T: 2°CAssay Description:48.5 .mu.L of substrate peptide solution (Biotin-XSEVNLDAEFRHDSGC-Eu: X=.epsilon.-amino-n-capronic acid, Eu=Europium cryptate) was added to each well...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2015
Entry Details
US Patent

TargetBeta-secretase 1(Human)
Shionogi

US Patent
LigandChemical structure of BindingDB Monomer ID 153628BDBM153628(US8999980, I-5)
Affinity DataIC50: 3.00E+4nMpH: 5.0 T: 2°CAssay Description:48.5 .mu.L of substrate peptide solution (Biotin-XSEVNLDAEFRHDSGC-Eu: X=.epsilon.-amino-n-capronic acid, Eu=Europium cryptate) was added to each well...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2015
Entry Details
US Patent

TargetBeta-secretase 1(Human)
Shionogi

US Patent
LigandChemical structure of BindingDB Monomer ID 153629BDBM153629(US8999980, I-7)
Affinity DataIC50: 3.00E+4nMpH: 5.0 T: 2°CAssay Description:48.5 .mu.L of substrate peptide solution (Biotin-XSEVNLDAEFRHDSGC-Eu: X=.epsilon.-amino-n-capronic acid, Eu=Europium cryptate) was added to each well...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2015
Entry Details
US Patent