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Found 16 Enz. Inhib. hit(s) with all data for entry = 6888
TargetBeta-secretase 1(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM156246(US9018391, 8)
Affinity DataIC50:  1.90nMpH: 4.4Assay Description:The inhibitory activity of compounds was assessed by a fluorescence quench assay of BACE1 activity using commercially available substrate HiLyte Fluo...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetBeta-secretase 1(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM156243(US9018391, 5)
Affinity DataIC50:  2.60nMpH: 4.4Assay Description:The inhibitory activity of compounds was assessed by a fluorescence quench assay of BACE1 activity using commercially available substrate HiLyte Fluo...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetBeta-secretase 1(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM156242(US9018391, 4)
Affinity DataIC50:  2.70nMpH: 4.4Assay Description:The inhibitory activity of compounds was assessed by a fluorescence quench assay of BACE1 activity using commercially available substrate HiLyte Fluo...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetBeta-secretase 1(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM156241(US9018391, 3)
Affinity DataIC50:  3nMpH: 4.4Assay Description:The inhibitory activity of compounds was assessed by a fluorescence quench assay of BACE1 activity using commercially available substrate HiLyte Fluo...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetBeta-secretase 1(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM156245(US9018391, 7)
Affinity DataIC50:  3.40nMpH: 4.4Assay Description:The inhibitory activity of compounds was assessed by a fluorescence quench assay of BACE1 activity using commercially available substrate HiLyte Fluo...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetBeta-secretase 1(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM156252(US9018391, 14)
Affinity DataIC50:  4.5nMpH: 4.4Assay Description:The inhibitory activity of compounds was assessed by a fluorescence quench assay of BACE1 activity using commercially available substrate HiLyte Fluo...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetBeta-secretase 1(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM156244(US9018391, 6)
Affinity DataIC50:  6.30nMpH: 4.4Assay Description:The inhibitory activity of compounds was assessed by a fluorescence quench assay of BACE1 activity using commercially available substrate HiLyte Fluo...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetBeta-secretase 1(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM156250(US9018391, 12)
Affinity DataIC50:  6.80nMpH: 4.4Assay Description:The inhibitory activity of compounds was assessed by a fluorescence quench assay of BACE1 activity using commercially available substrate HiLyte Fluo...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetBeta-secretase 1(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM156251(US9018391, 13)
Affinity DataIC50:  8.70nMpH: 4.4Assay Description:The inhibitory activity of compounds was assessed by a fluorescence quench assay of BACE1 activity using commercially available substrate HiLyte Fluo...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetBeta-secretase 1(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM156254(US9018391, 16)
Affinity DataIC50:  9.40nMpH: 4.4Assay Description:The inhibitory activity of compounds was assessed by a fluorescence quench assay of BACE1 activity using commercially available substrate HiLyte Fluo...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetBeta-secretase 1(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM156253(US9018391, 15)
Affinity DataIC50:  9.70nMpH: 4.4Assay Description:The inhibitory activity of compounds was assessed by a fluorescence quench assay of BACE1 activity using commercially available substrate HiLyte Fluo...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetBeta-secretase 1(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM156240(US9018391, 2)
Affinity DataIC50:  10.3nMpH: 4.4Assay Description:The inhibitory activity of compounds was assessed by a fluorescence quench assay of BACE1 activity using commercially available substrate HiLyte Fluo...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetBeta-secretase 1(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM156248(US9018391, 10)
Affinity DataIC50:  10.6nMpH: 4.4Assay Description:The inhibitory activity of compounds was assessed by a fluorescence quench assay of BACE1 activity using commercially available substrate HiLyte Fluo...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetBeta-secretase 1(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM156247(US9018391, 9)
Affinity DataIC50:  10.7nMpH: 4.4Assay Description:The inhibitory activity of compounds was assessed by a fluorescence quench assay of BACE1 activity using commercially available substrate HiLyte Fluo...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetBeta-secretase 1(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM156239(US9018391, 1)
Affinity DataIC50:  14.6nMpH: 4.4Assay Description:The inhibitory activity of compounds was assessed by a fluorescence quench assay of BACE1 activity using commercially available substrate HiLyte Fluo...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetBeta-secretase 1(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM156249(US9018391, 11)
Affinity DataIC50:  14.6nMpH: 4.4Assay Description:The inhibitory activity of compounds was assessed by a fluorescence quench assay of BACE1 activity using commercially available substrate HiLyte Fluo...More data for this Ligand-Target Pair
In DepthDetails US Patent