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Report error Found 28 Enz. Inhib. hit(s) with all data for entry = 6943
Target5-hydroxytryptamine receptor 3A(Human)
Albany Molecular Research

US Patent
LigandChemical structure of BindingDB Monomer ID 50334454BDBM50334454(Ramosetron | CHEMBL1643895 | US9045501, Ramosetron)
Affinity DataKi:  0.0600nM ΔG°:  -58.3kJ/molepH: 7.5 T: 2°CAssay Description:The relative affinity of the various compounds for the human 5-HT3 receptor was measured in a radioligand binding assay, using a scintillation proxim...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2016
Entry Details
US Patent

Target5-hydroxytryptamine receptor 3A(Human)
Albany Molecular Research

US Patent
LigandChemical structure of BindingDB Monomer ID 50014549BDBM50014549(CHEMBL3261480 | US9045501, 4)
Affinity DataKi:  0.200nM ΔG°:  -55.4kJ/molepH: 7.5 T: 2°CAssay Description:The relative affinity of the various compounds for the human 5-HT3 receptor was measured in a radioligand binding assay, using a scintillation proxim...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2016
Entry Details
US Patent

Target5-hydroxytryptamine receptor 3A(Human)
Albany Molecular Research

US Patent
LigandChemical structure of BindingDB Monomer ID 50014552BDBM50014552(CHEMBL3261483 | US9045501, 8)
Affinity DataKi:  0.5nM ΔG°:  -53.1kJ/molepH: 7.5 T: 2°CAssay Description:The relative affinity of the various compounds for the human 5-HT3 receptor was measured in a radioligand binding assay, using a scintillation proxim...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2016
Entry Details
US Patent

Target5-hydroxytryptamine receptor 3A(Human)
Albany Molecular Research

US Patent
LigandChemical structure of BindingDB Monomer ID 50014558BDBM50014558(CHEBI:253342 | Lotronex | ALOSETRON | US9045501, A...)
Affinity DataKi:  0.5nM ΔG°:  -53.1kJ/molepH: 7.5 T: 2°CAssay Description:The relative affinity of the various compounds for the human 5-HT3 receptor was measured in a radioligand binding assay, using a scintillation proxim...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2016
Entry Details
US Patent

Target5-hydroxytryptamine receptor 3A(Human)
Albany Molecular Research

US Patent
LigandChemical structure of BindingDB Monomer ID 160716BDBM160716(US9045501, 11)
Affinity DataKi:  0.800nM ΔG°:  -51.9kJ/molepH: 7.5 T: 2°CAssay Description:The relative affinity of the various compounds for the human 5-HT3 receptor was measured in a radioligand binding assay, using a scintillation proxim...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2016
Entry Details
US Patent

Target5-hydroxytryptamine receptor 3A(Human)
Albany Molecular Research

US Patent
LigandChemical structure of BindingDB Monomer ID 160732BDBM160732(US9045501, 29)
Affinity DataKi:  2nM ΔG°:  -49.7kJ/molepH: 7.5 T: 2°CAssay Description:The relative affinity of the various compounds for the human 5-HT3 receptor was measured in a radioligand binding assay, using a scintillation proxim...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2016
Entry Details
US Patent

Target5-hydroxytryptamine receptor 3A(Human)
Albany Molecular Research

US Patent
LigandChemical structure of BindingDB Monomer ID 160717BDBM160717(US9045501, 12)
Affinity DataKi:  2nM ΔG°:  -49.7kJ/molepH: 7.5 T: 2°CAssay Description:The relative affinity of the various compounds for the human 5-HT3 receptor was measured in a radioligand binding assay, using a scintillation proxim...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2016
Entry Details
US Patent

Target5-hydroxytryptamine receptor 3A(Human)
Albany Molecular Research

US Patent
LigandChemical structure of BindingDB Monomer ID 50014548BDBM50014548(CHEMBL3261479 | US9045501, 2)
Affinity DataKi:  4nM ΔG°:  -47.9kJ/molepH: 7.5 T: 2°CAssay Description:The relative affinity of the various compounds for the human 5-HT3 receptor was measured in a radioligand binding assay, using a scintillation proxim...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2016
Entry Details
US Patent

Target5-hydroxytryptamine receptor 3A(Human)
Albany Molecular Research

US Patent
LigandChemical structure of BindingDB Monomer ID 160711BDBM160711(US9045501, 3)
Affinity DataKi:  5nM ΔG°:  -47.4kJ/molepH: 7.5 T: 2°CAssay Description:The relative affinity of the various compounds for the human 5-HT3 receptor was measured in a radioligand binding assay, using a scintillation proxim...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2016
Entry Details
US Patent

Target5-hydroxytryptamine receptor 3A(Human)
Albany Molecular Research

US Patent
LigandChemical structure of BindingDB Monomer ID 160714BDBM160714(US9045501, 9)
Affinity DataKi:  6nM ΔG°:  -46.9kJ/molepH: 7.5 T: 2°CAssay Description:The relative affinity of the various compounds for the human 5-HT3 receptor was measured in a radioligand binding assay, using a scintillation proxim...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2016
Entry Details
US Patent

Target5-hydroxytryptamine receptor 3A(Human)
Albany Molecular Research

US Patent
LigandChemical structure of BindingDB Monomer ID 50014556BDBM50014556(CHEMBL3261486 | US9045501, 25)
Affinity DataKi:  7nM ΔG°:  -46.5kJ/molepH: 7.5 T: 2°CAssay Description:The relative affinity of the various compounds for the human 5-HT3 receptor was measured in a radioligand binding assay, using a scintillation proxim...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2016
Entry Details
US Patent

Target5-hydroxytryptamine receptor 3A(Human)
Albany Molecular Research

US Patent
LigandChemical structure of BindingDB Monomer ID 50014550BDBM50014550(CHEMBL3261481 | US9045501, 7)
Affinity DataKi:  8nM ΔG°:  -46.2kJ/molepH: 7.5 T: 2°CAssay Description:The relative affinity of the various compounds for the human 5-HT3 receptor was measured in a radioligand binding assay, using a scintillation proxim...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2016
Entry Details
US Patent

Target5-hydroxytryptamine receptor 3A(Human)
Albany Molecular Research

US Patent
LigandChemical structure of BindingDB Monomer ID 160730BDBM160730(US9045501, 27)
Affinity DataKi:  8nM ΔG°:  -46.2kJ/molepH: 7.5 T: 2°CAssay Description:The relative affinity of the various compounds for the human 5-HT3 receptor was measured in a radioligand binding assay, using a scintillation proxim...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2016
Entry Details
US Patent

Target5-hydroxytryptamine receptor 3A(Human)
Albany Molecular Research

US Patent
LigandChemical structure of BindingDB Monomer ID 160715BDBM160715(US9045501, 10)
Affinity DataKi:  14nM ΔG°:  -44.8kJ/molepH: 7.5 T: 2°CAssay Description:The relative affinity of the various compounds for the human 5-HT3 receptor was measured in a radioligand binding assay, using a scintillation proxim...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2016
Entry Details
US Patent

Target5-hydroxytryptamine receptor 3A(Human)
Albany Molecular Research

US Patent
LigandChemical structure of BindingDB Monomer ID 160733BDBM160733(US9045501, 30 (Enant. A) | US9045501, 31 (Enant. B...)
Affinity DataKi:  24nM ΔG°:  -43.5kJ/molepH: 7.5 T: 2°CAssay Description:The relative affinity of the various compounds for the human 5-HT3 receptor was measured in a radioligand binding assay, using a scintillation proxim...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2016
Entry Details
US Patent

Target5-hydroxytryptamine receptor 3A(Human)
Albany Molecular Research

US Patent
LigandChemical structure of BindingDB Monomer ID 160731BDBM160731(US9045501, 28)
Affinity DataKi:  30nM ΔG°:  -42.9kJ/molepH: 7.5 T: 2°CAssay Description:The relative affinity of the various compounds for the human 5-HT3 receptor was measured in a radioligand binding assay, using a scintillation proxim...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2016
Entry Details
US Patent

Target5-hydroxytryptamine receptor 3A(Human)
Albany Molecular Research

US Patent
LigandChemical structure of BindingDB Monomer ID 160718BDBM160718(US9045501, 13)
Affinity DataKi:  32nM ΔG°:  -42.8kJ/molepH: 7.5 T: 2°CAssay Description:The relative affinity of the various compounds for the human 5-HT3 receptor was measured in a radioligand binding assay, using a scintillation proxim...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2016
Entry Details
US Patent

Target5-hydroxytryptamine receptor 3A(Human)
Albany Molecular Research

US Patent
LigandChemical structure of BindingDB Monomer ID 160734BDBM160734(US9045501, 32)
Affinity DataKi:  73nM ΔG°:  -40.7kJ/molepH: 7.5 T: 2°CAssay Description:The relative affinity of the various compounds for the human 5-HT3 receptor was measured in a radioligand binding assay, using a scintillation proxim...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2016
Entry Details
US Patent

Target5-hydroxytryptamine receptor 3A(Human)
Albany Molecular Research

US Patent
LigandChemical structure of BindingDB Monomer ID 50014547BDBM50014547(CHEMBL3261478 | US9045501, 1)
Affinity DataKi:  74nM ΔG°:  -40.7kJ/molepH: 7.5 T: 2°CAssay Description:The relative affinity of the various compounds for the human 5-HT3 receptor was measured in a radioligand binding assay, using a scintillation proxim...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2016
Entry Details
US Patent

Target5-hydroxytryptamine receptor 3A(Human)
Albany Molecular Research

US Patent
LigandChemical structure of BindingDB Monomer ID 160722BDBM160722(US9045501, 17)
Affinity DataKi:  130nM ΔG°:  -39.3kJ/molepH: 7.5 T: 2°CAssay Description:The relative affinity of the various compounds for the human 5-HT3 receptor was measured in a radioligand binding assay, using a scintillation proxim...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2016
Entry Details
US Patent

Target5-hydroxytryptamine receptor 3A(Human)
Albany Molecular Research

US Patent
LigandChemical structure of BindingDB Monomer ID 160713BDBM160713(US9045501, 6)
Affinity DataKi:  205nM ΔG°:  -38.2kJ/molepH: 7.5 T: 2°CAssay Description:The relative affinity of the various compounds for the human 5-HT3 receptor was measured in a radioligand binding assay, using a scintillation proxim...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2016
Entry Details
US Patent

Target5-hydroxytryptamine receptor 3A(Human)
Albany Molecular Research

US Patent
LigandChemical structure of BindingDB Monomer ID 160728BDBM160728(US9045501, 23)
Affinity DataKi:  206nM ΔG°:  -38.2kJ/molepH: 7.5 T: 2°CAssay Description:The relative affinity of the various compounds for the human 5-HT3 receptor was measured in a radioligand binding assay, using a scintillation proxim...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2016
Entry Details
US Patent

Target5-hydroxytryptamine receptor 3A(Human)
Albany Molecular Research

US Patent
LigandChemical structure of BindingDB Monomer ID 160733BDBM160733(US9045501, 30 (Enant. A) | US9045501, 31 (Enant. B...)
Affinity DataKi:  217nM ΔG°:  -38.0kJ/molepH: 7.5 T: 2°CAssay Description:The relative affinity of the various compounds for the human 5-HT3 receptor was measured in a radioligand binding assay, using a scintillation proxim...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2016
Entry Details
US Patent

Target5-hydroxytryptamine receptor 3A(Human)
Albany Molecular Research

US Patent
LigandChemical structure of BindingDB Monomer ID 160735BDBM160735(US9045501, 33 (Enant. A) | US9045501, 34 (Enant. B...)
Affinity DataKi:  241nM ΔG°:  -37.8kJ/molepH: 7.5 T: 2°CAssay Description:The relative affinity of the various compounds for the human 5-HT3 receptor was measured in a radioligand binding assay, using a scintillation proxim...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2016
Entry Details
US Patent

Target5-hydroxytryptamine receptor 3A(Human)
Albany Molecular Research

US Patent
LigandChemical structure of BindingDB Monomer ID 160726BDBM160726(US9045501, 21)
Affinity DataKi:  406nM ΔG°:  -36.5kJ/molepH: 7.5 T: 2°CAssay Description:The relative affinity of the various compounds for the human 5-HT3 receptor was measured in a radioligand binding assay, using a scintillation proxim...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2016
Entry Details
US Patent

Target5-hydroxytryptamine receptor 3A(Human)
Albany Molecular Research

US Patent
LigandChemical structure of BindingDB Monomer ID 160712BDBM160712(US9045501, 5)
Affinity DataKi:  416nM ΔG°:  -36.4kJ/molepH: 7.5 T: 2°CAssay Description:The relative affinity of the various compounds for the human 5-HT3 receptor was measured in a radioligand binding assay, using a scintillation proxim...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2016
Entry Details
US Patent

Target5-hydroxytryptamine receptor 3A(Human)
Albany Molecular Research

US Patent
LigandChemical structure of BindingDB Monomer ID 160735BDBM160735(US9045501, 33 (Enant. A) | US9045501, 34 (Enant. B...)
Affinity DataKi:  579nM ΔG°:  -35.6kJ/molepH: 7.5 T: 2°CAssay Description:The relative affinity of the various compounds for the human 5-HT3 receptor was measured in a radioligand binding assay, using a scintillation proxim...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2016
Entry Details
US Patent

Target5-hydroxytryptamine receptor 3A(Human)
Albany Molecular Research

US Patent
LigandChemical structure of BindingDB Monomer ID 50014557BDBM50014557(CHEMBL3261487 | US9045501, 26)
Affinity DataKi:  701nM ΔG°:  -35.1kJ/molepH: 7.5 T: 2°CAssay Description:The relative affinity of the various compounds for the human 5-HT3 receptor was measured in a radioligand binding assay, using a scintillation proxim...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2016
Entry Details
US Patent