Compile Data Set for Download or QSAR
Report error Found 8 Enz. Inhib. hit(s) with all data for entry = 6966
TargetDipeptidyl peptidase 4(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM60417(US9051329, Example 1)
Affinity DataIC50: 1.70nMpH: 7.5 T: 2°CAssay Description:DPP4 activity was measured using a continuous fluorometric assay. The substrate, Gly-Pro-AMC, was cleaved by DPP4 to release the fluorescent AMC grou...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/25/2016
Entry Details
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PDB3D3D Structure (crystal)
TargetDipeptidyl peptidase 4(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM162377(US9051329, Example 2)
Affinity DataIC50: 10.6nMpH: 7.5 T: 2°CAssay Description:DPP4 activity was measured using a continuous fluorometric assay. The substrate, Gly-Pro-AMC, was cleaved by DPP4 to release the fluorescent AMC grou...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/25/2016
Entry Details
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TargetDipeptidyl peptidase 4(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM162383(US9051329, Example 8)
Affinity DataIC50: 11.2nMpH: 7.5 T: 2°CAssay Description:DPP4 activity was measured using a continuous fluorometric assay. The substrate, Gly-Pro-AMC, was cleaved by DPP4 to release the fluorescent AMC grou...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/25/2016
Entry Details
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TargetDipeptidyl peptidase 4(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM162381(US9051329, Example 6)
Affinity DataIC50: 13.5nMpH: 7.5 T: 2°CAssay Description:DPP4 activity was measured using a continuous fluorometric assay. The substrate, Gly-Pro-AMC, was cleaved by DPP4 to release the fluorescent AMC grou...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/25/2016
Entry Details
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TargetDipeptidyl peptidase 4(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM162376(US9051329, Example 4 | US9051329, Example 1)
Affinity DataIC50: 27.4nMpH: 7.5 T: 2°CAssay Description:DPP4 activity was measured using a continuous fluorometric assay. The substrate, Gly-Pro-AMC, was cleaved by DPP4 to release the fluorescent AMC grou...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/25/2016
Entry Details
Go to US Patent

TargetDipeptidyl peptidase 4(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM162380(US9051329, Example 5)
Affinity DataIC50: 123nMpH: 7.5 T: 2°CAssay Description:DPP4 activity was measured using a continuous fluorometric assay. The substrate, Gly-Pro-AMC, was cleaved by DPP4 to release the fluorescent AMC grou...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/25/2016
Entry Details
Go to US Patent

TargetDipeptidyl peptidase 4(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM162378(US9051329, Example 3)
Affinity DataIC50: 156nMpH: 7.5 T: 2°CAssay Description:DPP4 activity was measured using a continuous fluorometric assay. The substrate, Gly-Pro-AMC, was cleaved by DPP4 to release the fluorescent AMC grou...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/25/2016
Entry Details
Go to US Patent

TargetDipeptidyl peptidase 4(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM162382(US9051329, Example 7)
Affinity DataIC50: 625nMpH: 7.5 T: 2°CAssay Description:DPP4 activity was measured using a continuous fluorometric assay. The substrate, Gly-Pro-AMC, was cleaved by DPP4 to release the fluorescent AMC grou...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/25/2016
Entry Details
Go to US Patent