Compile Data Set for Download or QSAR
Report error Found 8 Enz. Inhib. hit(s) with all data for entry = 6966
TargetDipeptidyl peptidase 4(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 60417BDBM60417(US9051329, Example 1)
Affinity DataIC50: 1.70nMpH: 7.5 T: 2°CAssay Description:DPP4 activity was measured using a continuous fluorometric assay. The substrate, Gly-Pro-AMC, was cleaved by DPP4 to release the fluorescent AMC grou...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/25/2016
Entry Details
US Patent
PDB3D3D Structure (crystal)
TargetDipeptidyl peptidase 4(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 162377BDBM162377(US9051329, Example 2)
Affinity DataIC50: 10.6nMpH: 7.5 T: 2°CAssay Description:DPP4 activity was measured using a continuous fluorometric assay. The substrate, Gly-Pro-AMC, was cleaved by DPP4 to release the fluorescent AMC grou...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/25/2016
Entry Details
US Patent

TargetDipeptidyl peptidase 4(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 162383BDBM162383(US9051329, Example 8)
Affinity DataIC50: 11.2nMpH: 7.5 T: 2°CAssay Description:DPP4 activity was measured using a continuous fluorometric assay. The substrate, Gly-Pro-AMC, was cleaved by DPP4 to release the fluorescent AMC grou...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/25/2016
Entry Details
US Patent

TargetDipeptidyl peptidase 4(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 162381BDBM162381(US9051329, Example 6)
Affinity DataIC50: 13.5nMpH: 7.5 T: 2°CAssay Description:DPP4 activity was measured using a continuous fluorometric assay. The substrate, Gly-Pro-AMC, was cleaved by DPP4 to release the fluorescent AMC grou...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/25/2016
Entry Details
US Patent

TargetDipeptidyl peptidase 4(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 162376BDBM162376(US9051329, Example 4 | US9051329, Example 1)
Affinity DataIC50: 27.4nMpH: 7.5 T: 2°CAssay Description:DPP4 activity was measured using a continuous fluorometric assay. The substrate, Gly-Pro-AMC, was cleaved by DPP4 to release the fluorescent AMC grou...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/25/2016
Entry Details
US Patent

TargetDipeptidyl peptidase 4(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 162380BDBM162380(US9051329, Example 5)
Affinity DataIC50: 123nMpH: 7.5 T: 2°CAssay Description:DPP4 activity was measured using a continuous fluorometric assay. The substrate, Gly-Pro-AMC, was cleaved by DPP4 to release the fluorescent AMC grou...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/25/2016
Entry Details
US Patent

TargetDipeptidyl peptidase 4(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 162378BDBM162378(US9051329, Example 3)
Affinity DataIC50: 156nMpH: 7.5 T: 2°CAssay Description:DPP4 activity was measured using a continuous fluorometric assay. The substrate, Gly-Pro-AMC, was cleaved by DPP4 to release the fluorescent AMC grou...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/25/2016
Entry Details
US Patent

TargetDipeptidyl peptidase 4(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 162382BDBM162382(US9051329, Example 7)
Affinity DataIC50: 625nMpH: 7.5 T: 2°CAssay Description:DPP4 activity was measured using a continuous fluorometric assay. The substrate, Gly-Pro-AMC, was cleaved by DPP4 to release the fluorescent AMC grou...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/25/2016
Entry Details
US Patent