Compile Data Set for Download or QSAR
Report error Found 112 Enz. Inhib. hit(s) with all data for entry = 7079
LigandChemical structure of BindingDB Monomer ID 173175BDBM173175(US9096589, 8-Methoxy-5-methyl-2-{2-[1-(2-morpholin...)
Affinity DataIC50: 0.330nMT: 2°CAssay Description:A PDE10A assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2016
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 173179BDBM173179(US9096589, 5,8-Dimethyl-2-[2-(1-methyl-4-thiophen-...)
Affinity DataIC50: 0.390nMT: 2°CAssay Description:A PDE10A assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2016
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 173191BDBM173191(US9096589, 5,8-Dimethyl-2-[2-(1-methyl-4-thiazol-4...)
Affinity DataIC50: 0.400nMT: 2°CAssay Description:A PDE10A assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2016
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 173192BDBM173192(US9096589, 5,8-Dimethyl-2-[2-(1-methyl-4-pyrimidin...)
Affinity DataIC50: 0.440nMT: 2°CAssay Description:A PDE10A assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2016
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 173193BDBM173193(US9096589, 5,8-Dimethyl-2-[2-(1-methyl-4-pyrazin-2...)
Affinity DataIC50: 0.520nMT: 2°CAssay Description:A PDE10A assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2016
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 173112BDBM173112(US9096589, 5-Methyl-2-[2-(4-thiophen-2-yl-1H-imida...)
Affinity DataIC50: 0.540nMT: 2°CAssay Description:A PDE10A assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2016
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 173194BDBM173194(US9096589, 5,8-Dimethyl-2-[2-(1-methyl-4-pyridin-4...)
Affinity DataIC50: 0.550nMT: 2°CAssay Description:A PDE10A assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2016
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 173113BDBM173113(US9096589, 8-Methyl-2-[2-(4-thiophen-2-yl-1H-imida...)
Affinity DataIC50: 0.990nMT: 2°CAssay Description:A PDE10A assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2016
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 173171BDBM173171(US9096589, 5,8-Dimethyl-2-[2-(1-methyl-4-thiophen-...)
Affinity DataIC50: 1nMT: 2°CAssay Description:A PDE10A assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2016
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 173170BDBM173170(US9096589, 8-Methoxy-5-methyl-2-[2-(4-thiophen-2-y...)
Affinity DataIC50: 1.10nMT: 2°CAssay Description:A PDE10A assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2016
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 173172BDBM173172(US9096589, 8-Methoxy-5-methyl-2-[2-(1-propyl-4-thi...)
Affinity DataIC50: 1.20nMT: 2°CAssay Description:A PDE10A assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2016
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 173190BDBM173190(US9096589, 5,8-Dimethyl-2-[2-(1-methyl-4-thiazol-4...)
Affinity DataIC50: 1.29nMT: 2°CAssay Description:A PDE10A assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2016
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 173140BDBM173140(US9096589, 8-Methoxy-5-methyl-2-[2-(1-methyl-4-thi...)
Affinity DataIC50: 1.5nMT: 2°CAssay Description:A PDE10A assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2016
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 173176BDBM173176(US9096589, 8-Methoxy-5-methyl-2-[2-(1-methyl-4-thi...)
Affinity DataIC50: 1.70nMT: 2°CAssay Description:A PDE10A assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2016
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 173174BDBM173174(US9096589, 4-{2-[2-(8-Methoxy-5-methyl-[1,2,4]tria...)
Affinity DataIC50: 1.70nMT: 2°CAssay Description:A PDE10A assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2016
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 173180BDBM173180(US9096589, 5,8-Dimethyl-2-[2-(1-methyl-4-thiazol-2...)
Affinity DataIC50: 2.30nMT: 2°CAssay Description:A PDE10A assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2016
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 173129BDBM173129(US9096589, 8-Methoxy-5-methyl-2-[(E)-2-(1-methyl-4...)
Affinity DataIC50: 2.70nMT: 2°CAssay Description:A PDE10A assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2016
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 173181BDBM173181(US9096589, 5,8-Dimethyl-2-[2-(1-methyl-4-thiazol-2...)
Affinity DataIC50: 2.70nMT: 2°CAssay Description:A PDE10A assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2016
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 173137BDBM173137(US9096589, (R)-1-Chloro-3-{2-[2-(5-methyl-[1,2,4]t...)
Affinity DataIC50: 2.80nMT: 2°CAssay Description:A PDE10A assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2016
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 173187BDBM173187(US9096589, 2-[2-(4-Furan-3-yl-1-methyl-1H-imidazol...)
Affinity DataIC50: 2.90nMT: 2°CAssay Description:A PDE10A assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2016
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 173182BDBM173182(US9096589, 8-Methoxy-5-methyl-2-{2-[1-methyl-4-(4-...)
Affinity DataIC50: 3.10nMT: 2°CAssay Description:A PDE10A assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2016
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 173102BDBM173102(US9669029, 23 5,7-Dimethyl-2-[2-(1-propyl-4-thioph...)
Affinity DataIC50: 3.40nMT: 2°CAssay Description:A PDE10A assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2016
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 173177BDBM173177(US9096589, 2-[2-(4-Furan-3-yl-1-methyl-1H-imidazol...)
Affinity DataIC50: 4nMT: 2°CAssay Description:A PDE10A assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2016
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 173173BDBM173173(US9096589, 8-Methoxy-5-methyl-2-[2-(1-prop-2-ynyl-...)
Affinity DataIC50: 4.10nMT: 2°CAssay Description:A PDE10A assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2016
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 173130BDBM173130(US9096589, 5,7-Dimethyl-2-[2-(1-methyl-4-thiophen-...)
Affinity DataIC50: 4.20nMT: 2°CAssay Description:A PDE10A assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2016
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 173185BDBM173185(US9096589, 5,8-Dimethyl-2-{2-[1-methyl-4-(5-methyl...)
Affinity DataIC50: 4.20nMT: 2°CAssay Description:A PDE10A assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2016
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 173131BDBM173131(US9096589, 8-Methoxy-2-[2-(1-methyl-4-thiophen-2-y...)
Affinity DataIC50: 4.5nMT: 2°CAssay Description:A PDE10A assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2016
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 173111BDBM173111(US9096589, 1-(4-Chloro-phenyl)-2-{2-[2-(5,7-dimeth...)
Affinity DataIC50: 5.70nMT: 2°CAssay Description:A PDE10A assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2016
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 173119BDBM173119(US9096589, 5-Methyl-2-[2-(4-thiophen-3-yl-1H-imida...)
Affinity DataIC50: 5.70nMT: 2°CAssay Description:A PDE10A assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2016
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 173183BDBM173183(US9096589, 5,8-Dimethyl-2-[2-(1-methyl-4-pyridin-3...)
Affinity DataIC50: 5.70nMT: 2°CAssay Description:A PDE10A assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2016
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 173114BDBM173114(US9096589, (S)-2-{2-[2-(5-Methyl-[1,2,4]triazolo[1...)
Affinity DataIC50: 6.40nMT: 2°CAssay Description:A PDE10A assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2016
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 173178BDBM173178(US9096589, 5,8-Dimethyl-2-{2-[1-methyl-4-(5-methyl...)
Affinity DataIC50: 6.80nMT: 2°CAssay Description:A PDE10A assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2016
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 173105BDBM173105(US9669029, 26 5,7-Dimethyl-2-{2-[1-(3-methyl-butyl...)
Affinity DataIC50: 6.80nMT: 2°CAssay Description:A PDE10A assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2016
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 173189BDBM173189(US9096589, 5,8-Dimethyl-2-[2-(1-methyl-4-thiazol-5...)
Affinity DataIC50: 6.90nMT: 2°CAssay Description:A PDE10A assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2016
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 173115BDBM173115(US9096589, 1-Methoxy-3-{2-[2-(5-methyl-[1,2,4]tria...)
Affinity DataIC50: 7.5nMT: 2°CAssay Description:A PDE10A assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2016
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 173096BDBM173096(US9669029, 17 5,7-Dimethyl-2-[2-(4-thiophen-2-yl-1...)
Affinity DataIC50: 7.60nMT: 2°CAssay Description:A PDE10A assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2016
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 173101BDBM173101(US9096589, 1-{2-[2-(5,7-Dimethyl-imidazo[1,2-a]pyr...)
Affinity DataIC50: 7.90nMT: 2°CAssay Description:A PDE10A assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2016
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 173161BDBM173161(US9096589, 1-Methoxy-3-{2-[2-(8-methyl-[1,2,4]tria...)
Affinity DataIC50: 8.40nMT: 2°CAssay Description:A PDE10A assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2016
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 173153BDBM173153(US9096589, [((S)-2-Hydroxy-3-{2-[2-(5-methyl-[1,2,...)
Affinity DataIC50: 8.80nMT: 2°CAssay Description:A PDE10A assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2016
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 173100BDBM173100(US9669029, 21 (S)-2-{2-[2-(5,7-Dimethyl-imidazo[1,...)
Affinity DataIC50: 8.80nMT: 2°CAssay Description:A PDE10A assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2016
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 173083BDBM173083(US9669029, 3 5,7-Dimethyl-2-[(E)-2-(1-methyl-4-thi...)
Affinity DataIC50: 8.80nMT: 2°CAssay Description:A PDE10A assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2016
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 173184BDBM173184(US9096589, 5,8-Dimethyl-2-[2-(1-methyl-4-pyridin-3...)
Affinity DataIC50: 8.90nMT: 2°CAssay Description:A PDE10A assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2016
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 173162BDBM173162(US9096589, 5-Methyl-2-[2-(1-methyl-4-thiophen-2-yl...)
Affinity DataIC50: 9.20nMT: 2°CAssay Description:A PDE10A assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2016
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 173168BDBM173168(US9096589, 8-Methoxy-5-methyl-2-[2-(1-methyl-4-thi...)
Affinity DataIC50: 9.20nMT: 2°CAssay Description:A PDE10A assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2016
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 173095BDBM173095(US9096589, 5,7-Dimethyl-2-{2-[4-thiophen-2-yl-1-(2...)
Affinity DataIC50: 9.60nMT: 2°CAssay Description:A PDE10A assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2016
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 173120BDBM173120(US9096589, 5-Methyl-2-[2-(4-pyridin-3-yl-1H-imidaz...)
Affinity DataIC50: 9.60nMT: 2°CAssay Description:A PDE10A assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2016
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 173120BDBM173120(US9096589, 5-Methyl-2-[2-(4-pyridin-3-yl-1H-imidaz...)
Affinity DataIC50: 9.60nMT: 2°CAssay Description:A PDE10A assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2016
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 60522BDBM60522(US9096589, 5,8-Dimethyl-2-[2-(1-methyl-4-thiazol-2...)
Affinity DataIC50: 12nMT: 2°CAssay Description:A PDE10A assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2016
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 173106BDBM173106(US9096589, 2-[2-(1-Isobutyl-4-thiophen-2-yl-1H-imi...)
Affinity DataIC50: 12nMT: 2°CAssay Description:A PDE10A assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2016
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 173108BDBM173108(US9669029, 29 1-{2-[2-(5,7-Dimethyl-imidazo[1,2-a]...)
Affinity DataIC50: 14nMT: 2°CAssay Description:A PDE10A assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2016
Entry Details
US Patent

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