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Found 19 Enz. Inhib. hit(s) with all data for entry = 6948
TargetTransient receptor potential cation channel subfamily A member 1(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM161012(US9108905, 1 | US9186360, 89)
Affinity DataIC50:  74nMT: 2°CAssay Description:Ca2+ influx was measured using a FLIPR calcium assay kit (R8033; Molecular Devices, Sunnyvale, Calif.). The Ca2+ indicator dye was dissolved in Hanks...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTransient receptor potential cation channel subfamily A member 1(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM161015(US9108905, 4)
Affinity DataIC50:  500nMT: 2°CAssay Description:Ca2+ influx was measured using a FLIPR calcium assay kit (R8033; Molecular Devices, Sunnyvale, Calif.). The Ca2+ indicator dye was dissolved in Hanks...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTransient receptor potential cation channel subfamily A member 1(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM161025(US9108905, 14)
Affinity DataIC50:  574nMT: 2°CAssay Description:Ca2+ influx was measured using a FLIPR calcium assay kit (R8033; Molecular Devices, Sunnyvale, Calif.). The Ca2+ indicator dye was dissolved in Hanks...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTransient receptor potential cation channel subfamily A member 1(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM161021(US9108905, 10)
Affinity DataIC50:  701nMT: 2°CAssay Description:Ca2+ influx was measured using a FLIPR calcium assay kit (R8033; Molecular Devices, Sunnyvale, Calif.). The Ca2+ indicator dye was dissolved in Hanks...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTransient receptor potential cation channel subfamily A member 1(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM161018(US9108905, 7)
Affinity DataIC50:  850nMT: 2°CAssay Description:Ca2+ influx was measured using a FLIPR calcium assay kit (R8033; Molecular Devices, Sunnyvale, Calif.). The Ca2+ indicator dye was dissolved in Hanks...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTransient receptor potential cation channel subfamily A member 1(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM161019(US9108905, 8)
Affinity DataIC50:  3.30E+3nMT: 2°CAssay Description:Ca2+ influx was measured using a FLIPR calcium assay kit (R8033; Molecular Devices, Sunnyvale, Calif.). The Ca2+ indicator dye was dissolved in Hanks...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTransient receptor potential cation channel subfamily A member 1(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM161017(US9108905, 6)
Affinity DataIC50:  4.40E+3nMT: 2°CAssay Description:Ca2+ influx was measured using a FLIPR calcium assay kit (R8033; Molecular Devices, Sunnyvale, Calif.). The Ca2+ indicator dye was dissolved in Hanks...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTransient receptor potential cation channel subfamily A member 1(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM161014(US9108905, 3)
Affinity DataIC50:  4.60E+3nMT: 2°CAssay Description:Ca2+ influx was measured using a FLIPR calcium assay kit (R8033; Molecular Devices, Sunnyvale, Calif.). The Ca2+ indicator dye was dissolved in Hanks...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTransient receptor potential cation channel subfamily A member 1(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM161026(US9108905, 15)
Affinity DataIC50:  4.67E+3nMT: 2°CAssay Description:Ca2+ influx was measured using a FLIPR calcium assay kit (R8033; Molecular Devices, Sunnyvale, Calif.). The Ca2+ indicator dye was dissolved in Hanks...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTransient receptor potential cation channel subfamily A member 1(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM161023(US9108905, 12)
Affinity DataIC50:  5.91E+3nMT: 2°CAssay Description:Ca2+ influx was measured using a FLIPR calcium assay kit (R8033; Molecular Devices, Sunnyvale, Calif.). The Ca2+ indicator dye was dissolved in Hanks...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTransient receptor potential cation channel subfamily A member 1(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM161020(US9108905, 9)
Affinity DataIC50:  6.00E+3nMT: 2°CAssay Description:Ca2+ influx was measured using a FLIPR calcium assay kit (R8033; Molecular Devices, Sunnyvale, Calif.). The Ca2+ indicator dye was dissolved in Hanks...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTransient receptor potential cation channel subfamily A member 1(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM161016(US9108905, 5)
Affinity DataIC50:  8.00E+3nMT: 2°CAssay Description:Ca2+ influx was measured using a FLIPR calcium assay kit (R8033; Molecular Devices, Sunnyvale, Calif.). The Ca2+ indicator dye was dissolved in Hanks...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTransient receptor potential cation channel subfamily A member 1(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM161013(US9108905, 2)
Affinity DataIC50:  8.30E+3nMT: 2°CAssay Description:Ca2+ influx was measured using a FLIPR calcium assay kit (R8033; Molecular Devices, Sunnyvale, Calif.). The Ca2+ indicator dye was dissolved in Hanks...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTransient receptor potential cation channel subfamily A member 1(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM161024(US9108905, 13)
Affinity DataIC50:  9.46E+3nMT: 2°CAssay Description:Ca2+ influx was measured using a FLIPR calcium assay kit (R8033; Molecular Devices, Sunnyvale, Calif.). The Ca2+ indicator dye was dissolved in Hanks...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTransient receptor potential cation channel subfamily A member 1(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM161022(US9108905, 11)
Affinity DataIC50:  2.06E+4nMT: 2°CAssay Description:Ca2+ influx was measured using a FLIPR calcium assay kit (R8033; Molecular Devices, Sunnyvale, Calif.). The Ca2+ indicator dye was dissolved in Hanks...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTransient receptor potential cation channel subfamily A member 1(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM161030(US9108905, 19)
Affinity DataIC50: >1.00E+5nMT: 2°CAssay Description:Ca2+ influx was measured using a FLIPR calcium assay kit (R8033; Molecular Devices, Sunnyvale, Calif.). The Ca2+ indicator dye was dissolved in Hanks...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTransient receptor potential cation channel subfamily A member 1(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM161027(US9108905, 16)
Affinity DataIC50: >1.00E+5nMT: 2°CAssay Description:Ca2+ influx was measured using a FLIPR calcium assay kit (R8033; Molecular Devices, Sunnyvale, Calif.). The Ca2+ indicator dye was dissolved in Hanks...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTransient receptor potential cation channel subfamily A member 1(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM161028(US9108905, 17)
Affinity DataIC50: >1.00E+5nMT: 2°CAssay Description:Ca2+ influx was measured using a FLIPR calcium assay kit (R8033; Molecular Devices, Sunnyvale, Calif.). The Ca2+ indicator dye was dissolved in Hanks...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTransient receptor potential cation channel subfamily A member 1(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM161029(US9108905, 18)
Affinity DataIC50: >1.00E+5nMT: 2°CAssay Description:Ca2+ influx was measured using a FLIPR calcium assay kit (R8033; Molecular Devices, Sunnyvale, Calif.). The Ca2+ indicator dye was dissolved in Hanks...More data for this Ligand-Target Pair
In DepthDetails US Patent