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Report error Found 20 Enz. Inhib. hit(s) with all data for entry = 7128
TargetLysosomal acid glucosylceramidase(Mouse)
Amicus Therapeutics

US Patent
LigandPNGBDBM175515(US9119845, 16)
Affinity DataKi:  440nM IC50: 1.07E+3nM EC50:  6.90E+3nMpH: 4.5Assay Description:To 2.5 μl of supernatant (in 96-well plates) was added 17.5 μl reaction buffer (citrate phosphate buffer, pH 4.5, no Triton X-100), and 50 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2016
Entry Details
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TargetLysosomal acid glucosylceramidase(Mouse)
Amicus Therapeutics

US Patent
LigandPNGBDBM175523(US9119845, 24)
Affinity DataKi:  880nM IC50: 2.13E+3nM EC50:  3.05E+4nMpH: 4.5Assay Description:To 2.5 μl of supernatant (in 96-well plates) was added 17.5 μl reaction buffer (citrate phosphate buffer, pH 4.5, no Triton X-100), and 50 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2016
Entry Details
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TargetLysosomal acid glucosylceramidase(Mouse)
Amicus Therapeutics

US Patent
LigandPNGBDBM175503(US9119845, 4)
Affinity DataKi:  1.66E+3nM IC50: 4.00E+3nM EC50:  6.30E+4nMpH: 4.5Assay Description:To 2.5 μl of supernatant (in 96-well plates) was added 17.5 μl reaction buffer (citrate phosphate buffer, pH 4.5, no Triton X-100), and 50 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2016
Entry Details
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TargetLysosomal acid glucosylceramidase(Mouse)
Amicus Therapeutics

US Patent
LigandPNGBDBM175512(US9119845, 13)
Affinity DataKi:  3.11E+3nM IC50: 7.50E+3nM EC50:  2.20E+3nMpH: 4.5Assay Description:To 2.5 μl of supernatant (in 96-well plates) was added 17.5 μl reaction buffer (citrate phosphate buffer, pH 4.5, no Triton X-100), and 50 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2016
Entry Details
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TargetLysosomal acid glucosylceramidase(Mouse)
Amicus Therapeutics

US Patent
LigandPNGBDBM175504(US9119845, 5)
Affinity DataKi:  2.48E+3nM IC50: 5.99E+3nM EC50:  6.07E+4nMpH: 4.5Assay Description:To 2.5 μl of supernatant (in 96-well plates) was added 17.5 μl reaction buffer (citrate phosphate buffer, pH 4.5, no Triton X-100), and 50 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2016
Entry Details
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TargetLysosomal acid glucosylceramidase(Mouse)
Amicus Therapeutics

US Patent
LigandPNGBDBM175511(US9119845, 12)
Affinity DataKi:  3.88E+3nM IC50: 9.36E+3nM EC50:  7.70E+3nMpH: 4.5Assay Description:To 2.5 μl of supernatant (in 96-well plates) was added 17.5 μl reaction buffer (citrate phosphate buffer, pH 4.5, no Triton X-100), and 50 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2016
Entry Details
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TargetLysosomal acid glucosylceramidase(Mouse)
Amicus Therapeutics

US Patent
LigandPNGBDBM175507(US9119845, 8)
Affinity DataKi:  5.26E+3nM IC50: 1.27E+4nM EC50:  1.16E+4nMpH: 4.5Assay Description:To 2.5 μl of supernatant (in 96-well plates) was added 17.5 μl reaction buffer (citrate phosphate buffer, pH 4.5, no Triton X-100), and 50 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2016
Entry Details
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TargetLysosomal acid glucosylceramidase(Mouse)
Amicus Therapeutics

US Patent
LigandPNGBDBM175522(US9119845, 23)
Affinity DataKi:  6.48E+3nM IC50: 1.56E+4nM EC50:  1.88E+4nMpH: 4.5Assay Description:To 2.5 μl of supernatant (in 96-well plates) was added 17.5 μl reaction buffer (citrate phosphate buffer, pH 4.5, no Triton X-100), and 50 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2016
Entry Details
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TargetLysosomal acid glucosylceramidase(Mouse)
Amicus Therapeutics

US Patent
LigandPNGBDBM175518(US9119845, 19)
Affinity DataKi:  8.02E+3nM IC50: 1.94E+4nM EC50:  3.50E+4nMpH: 4.5Assay Description:To 2.5 μl of supernatant (in 96-well plates) was added 17.5 μl reaction buffer (citrate phosphate buffer, pH 4.5, no Triton X-100), and 50 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2016
Entry Details
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TargetLysosomal acid glucosylceramidase(Mouse)
Amicus Therapeutics

US Patent
LigandPNGBDBM175502(US9119845, 3)
Affinity DataKi:  1.73E+4nM IC50: 4.17E+4nM EC50:  9.99E+3nMpH: 4.5Assay Description:To 2.5 μl of supernatant (in 96-well plates) was added 17.5 μl reaction buffer (citrate phosphate buffer, pH 4.5, no Triton X-100), and 50 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2016
Entry Details
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TargetLysosomal acid glucosylceramidase(Mouse)
Amicus Therapeutics

US Patent
LigandPNGBDBM175517(US9119845, 18)
Affinity DataKi:  1.14E+4nM IC50: 2.76E+4nM EC50:  1.39E+5nMpH: 4.5Assay Description:To 2.5 μl of supernatant (in 96-well plates) was added 17.5 μl reaction buffer (citrate phosphate buffer, pH 4.5, no Triton X-100), and 50 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2016
Entry Details
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TargetLysosomal acid glucosylceramidase(Mouse)
Amicus Therapeutics

US Patent
LigandPNGBDBM175500(US9119845, 1)
Affinity DataKi:  1.48E+4nM IC50: 3.58E+4nM EC50:  6.59E+4nMpH: 4.5Assay Description:To 2.5 μl of supernatant (in 96-well plates) was added 17.5 μl reaction buffer (citrate phosphate buffer, pH 4.5, no Triton X-100), and 50 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2016
Entry Details
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TargetLysosomal acid glucosylceramidase(Mouse)
Amicus Therapeutics

US Patent
LigandPNGBDBM175524(US9119845, 25)
Affinity DataKi:  1.86E+4nM IC50: 4.50E+4nM EC50:  1.64E+4nMpH: 4.5Assay Description:To 2.5 μl of supernatant (in 96-well plates) was added 17.5 μl reaction buffer (citrate phosphate buffer, pH 4.5, no Triton X-100), and 50 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2016
Entry Details
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TargetLysosomal acid glucosylceramidase(Mouse)
Amicus Therapeutics

US Patent
LigandPNGBDBM175514(US9119845, 15)
Affinity DataKi:  2.04E+4nM IC50: 4.92E+4nM EC50:  6.83E+4nMpH: 4.5Assay Description:To 2.5 μl of supernatant (in 96-well plates) was added 17.5 μl reaction buffer (citrate phosphate buffer, pH 4.5, no Triton X-100), and 50 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2016
Entry Details
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TargetLysosomal acid glucosylceramidase(Mouse)
Amicus Therapeutics

US Patent
LigandPNGBDBM175506(US9119845, 7)
Affinity DataKi:  2.88E+4nM IC50: 6.95E+4nM EC50:  4.64E+4nMpH: 4.5Assay Description:To 2.5 μl of supernatant (in 96-well plates) was added 17.5 μl reaction buffer (citrate phosphate buffer, pH 4.5, no Triton X-100), and 50 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2016
Entry Details
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TargetLysosomal acid glucosylceramidase(Mouse)
Amicus Therapeutics

US Patent
LigandPNGBDBM175508(US9119845, 9)
Affinity DataKi:  5.37E+4nM IC50: 1.30E+5nM EC50:  1.45E+5nMpH: 4.5Assay Description:To 2.5 μl of supernatant (in 96-well plates) was added 17.5 μl reaction buffer (citrate phosphate buffer, pH 4.5, no Triton X-100), and 50 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2016
Entry Details
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TargetLysosomal acid glucosylceramidase(Mouse)
Amicus Therapeutics

US Patent
LigandPNGBDBM175516(US9119845, 17)
Affinity DataKi:  1.16E+5nM IC50: 2.80E+5nM EC50:  6.56E+4nMpH: 4.5Assay Description:To 2.5 μl of supernatant (in 96-well plates) was added 17.5 μl reaction buffer (citrate phosphate buffer, pH 4.5, no Triton X-100), and 50 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2016
Entry Details
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TargetLysosomal acid glucosylceramidase(Mouse)
Amicus Therapeutics

US Patent
LigandPNGBDBM175509(US9119845, 10)
Affinity DataKi:  1.12E+5nM IC50: 2.70E+5nM EC50:  7.06E+4nMpH: 4.5Assay Description:To 2.5 μl of supernatant (in 96-well plates) was added 17.5 μl reaction buffer (citrate phosphate buffer, pH 4.5, no Triton X-100), and 50 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2016
Entry Details
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TargetLysosomal acid glucosylceramidase(Mouse)
Amicus Therapeutics

US Patent
LigandPNGBDBM175505(US9119845, 6)
Affinity DataKi:  8.30E+4nM IC50: 2.00E+5nM EC50:  1.15E+5nMpH: 4.5Assay Description:To 2.5 μl of supernatant (in 96-well plates) was added 17.5 μl reaction buffer (citrate phosphate buffer, pH 4.5, no Triton X-100), and 50 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2016
Entry Details
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TargetLysosomal acid glucosylceramidase(Mouse)
Amicus Therapeutics

US Patent
LigandPNGBDBM175501(US9119845, 2)
Affinity DataKi:  4.06E+5nM IC50: 9.80E+5nM EC50:  2.66E+5nMpH: 4.5Assay Description:To 2.5 μl of supernatant (in 96-well plates) was added 17.5 μl reaction buffer (citrate phosphate buffer, pH 4.5, no Triton X-100), and 50 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2016
Entry Details
Go to US Patent