Compile Data Set for Download or QSAR
Report error Found 32 Enz. Inhib. hit(s) with all data for entry = 7221
TargetCannabinoid receptor 2(Human)
The University of Tennessee Research Foundation

US Patent
LigandPNGBDBM50312840([11C](3',5'-dichloro-2,6-dimethoxybiphenyl-4-yl)(t...)
Affinity DataKi:  0.270nM ΔG°:  -55.5kJ/moleT: 2°CAssay Description:15.3 ug of membranes (20 ul of 1:20 dilution in incubation buffer) was incubated with 5 ul of drug solution (10E-4M to 10E-12M) and 5ul of 5.4 nM [3H...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2016
Entry Details
Go to US Patent

TargetCannabinoid receptor 2(Human)
The University of Tennessee Research Foundation

US Patent
LigandPNGBDBM50248606(3',5'-dichloro-4-(2-phenylpropan-2-yl)biphenyl-2,6...)
Affinity DataKi:  1.07nM ΔG°:  -52.1kJ/moleT: 2°CAssay Description:15.3 ug of membranes (20 ul of 1:20 dilution in incubation buffer) was incubated with 5 ul of drug solution (10E-4M to 10E-12M) and 5ul of 5.4 nM [3H...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2016
Entry Details
Go to US Patent

TargetCannabinoid receptor 2(Human)
The University of Tennessee Research Foundation

US Patent
LigandPNGBDBM181244(US9139546, 42)
Affinity DataKi:  1.40nM ΔG°:  -51.4kJ/moleT: 2°CAssay Description:15.3 ug of membranes (20 ul of 1:20 dilution in incubation buffer) was incubated with 5 ul of drug solution (10E-4M to 10E-12M) and 5ul of 5.4 nM [3H...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2016
Entry Details
Go to US Patent

TargetCannabinoid receptor 2(Human)
The University of Tennessee Research Foundation

US Patent
LigandPNGBDBM50248603((3',5'-dichloro-2,6-dimethoxybiphenyl-4-yl)(phenyl...)
Affinity DataKi:  1.66nM ΔG°:  -51.0kJ/moleT: 2°CAssay Description:15.3 ug of membranes (20 ul of 1:20 dilution in incubation buffer) was incubated with 5 ul of drug solution (10E-4M to 10E-12M) and 5ul of 5.4 nM [3H...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2016
Entry Details
Go to US Patent

TargetCannabinoid receptor 2(Human)
The University of Tennessee Research Foundation

US Patent
LigandPNGBDBM181241(US9139546, 31)
Affinity DataKi:  1.75nM ΔG°:  -50.8kJ/moleT: 2°CAssay Description:15.3 ug of membranes (20 ul of 1:20 dilution in incubation buffer) was incubated with 5 ul of drug solution (10E-4M to 10E-12M) and 5ul of 5.4 nM [3H...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2016
Entry Details
Go to US Patent

TargetCannabinoid receptor 2(Human)
The University of Tennessee Research Foundation

US Patent
LigandPNGBDBM181243(US9139546, 40)
Affinity DataKi:  2.30nM ΔG°:  -50.1kJ/moleT: 2°CAssay Description:15.3 ug of membranes (20 ul of 1:20 dilution in incubation buffer) was incubated with 5 ul of drug solution (10E-4M to 10E-12M) and 5ul of 5.4 nM [3H...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2016
Entry Details
Go to US Patent

TargetCannabinoid receptor 2(Human)
The University of Tennessee Research Foundation

US Patent
LigandPNGBDBM50312841([11C](3',5'-dichloro-2-hydroxy-6-methoxybiphenyl-4...)
Affinity DataKi:  2.32nM ΔG°:  -50.1kJ/moleT: 2°CAssay Description:15.3 ug of membranes (20 ul of 1:20 dilution in incubation buffer) was incubated with 5 ul of drug solution (10E-4M to 10E-12M) and 5ul of 5.4 nM [3H...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2016
Entry Details
Go to US Patent

TargetCannabinoid receptor 1(Human)
The University of Tennessee Research Foundation

US Patent
LigandPNGBDBM181246(US9139546, 44)
Affinity DataKi:  2.33nM ΔG°:  -50.1kJ/moleT: 2°CAssay Description:8 ug of membranes (20 ul of 1:8 dilution in incubation buffer) was incubated with 5 ul of drug solution (10E-4M to 10E-12M) and 5ul of 5.4 nM [3H]CP5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2016
Entry Details
Go to US Patent

TargetCannabinoid receptor 2(Human)
The University of Tennessee Research Foundation

US Patent
LigandPNGBDBM50248604((3',5'-dichloro-2,6-dihydroxybiphenyl-4-yl)(phenyl...)
Affinity DataKi:  2.94nM ΔG°:  -49.5kJ/moleT: 2°CAssay Description:15.3 ug of membranes (20 ul of 1:20 dilution in incubation buffer) was incubated with 5 ul of drug solution (10E-4M to 10E-12M) and 5ul of 5.4 nM [3H...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2016
Entry Details
Go to US Patent

TargetCannabinoid receptor 1(Human)
The University of Tennessee Research Foundation

US Patent
LigandPNGBDBM181245(US9139546, 43)
Affinity DataKi:  3.70nM ΔG°:  -48.9kJ/moleT: 2°CAssay Description:8 ug of membranes (20 ul of 1:8 dilution in incubation buffer) was incubated with 5 ul of drug solution (10E-4M to 10E-12M) and 5ul of 5.4 nM [3H]CP5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2016
Entry Details
Go to US Patent

TargetCannabinoid receptor 2(Human)
The University of Tennessee Research Foundation

US Patent
LigandPNGBDBM181242(US9139546, 39)
Affinity DataKi:  4.70nM ΔG°:  -48.3kJ/moleT: 2°CAssay Description:15.3 ug of membranes (20 ul of 1:20 dilution in incubation buffer) was incubated with 5 ul of drug solution (10E-4M to 10E-12M) and 5ul of 5.4 nM [3H...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2016
Entry Details
Go to US Patent

TargetCannabinoid receptor 2(Human)
The University of Tennessee Research Foundation

US Patent
LigandPNGBDBM50248605((3',5'-dichloro-2-hydroxy-6-methoxybiphenyl-4-yl)(...)
Affinity DataKi:  4.77nM ΔG°:  -48.3kJ/moleT: 2°CAssay Description:15.3 ug of membranes (20 ul of 1:20 dilution in incubation buffer) was incubated with 5 ul of drug solution (10E-4M to 10E-12M) and 5ul of 5.4 nM [3H...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2016
Entry Details
Go to US Patent

TargetCannabinoid receptor 2(Human)
The University of Tennessee Research Foundation

US Patent
LigandPNGBDBM181246(US9139546, 44)
Affinity DataKi:  5.69nM ΔG°:  -47.8kJ/moleT: 2°CAssay Description:15.3 ug of membranes (20 ul of 1:20 dilution in incubation buffer) was incubated with 5 ul of drug solution (10E-4M to 10E-12M) and 5ul of 5.4 nM [3H...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2016
Entry Details
Go to US Patent

TargetCannabinoid receptor 1(Human)
The University of Tennessee Research Foundation

US Patent
LigandPNGBDBM181247(US9139546, 45)
Affinity DataKi:  17.2nM ΔG°:  -45.1kJ/moleT: 2°CAssay Description:8 ug of membranes (20 ul of 1:8 dilution in incubation buffer) was incubated with 5 ul of drug solution (10E-4M to 10E-12M) and 5ul of 5.4 nM [3H]CP5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2016
Entry Details
Go to US Patent

TargetCannabinoid receptor 1(Human)
The University of Tennessee Research Foundation

US Patent
LigandPNGBDBM50248604((3',5'-dichloro-2,6-dihydroxybiphenyl-4-yl)(phenyl...)
Affinity DataKi:  27nM ΔG°:  -43.9kJ/moleT: 2°CAssay Description:8 ug of membranes (20 ul of 1:8 dilution in incubation buffer) was incubated with 5 ul of drug solution (10E-4M to 10E-12M) and 5ul of 5.4 nM [3H]CP5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2016
Entry Details
Go to US Patent

TargetCannabinoid receptor 2(Human)
The University of Tennessee Research Foundation

US Patent
LigandPNGBDBM181247(US9139546, 45)
Affinity DataKi:  37.2nM ΔG°:  -43.1kJ/moleT: 2°CAssay Description:15.3 ug of membranes (20 ul of 1:20 dilution in incubation buffer) was incubated with 5 ul of drug solution (10E-4M to 10E-12M) and 5ul of 5.4 nM [3H...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2016
Entry Details
Go to US Patent

TargetCannabinoid receptor 1(Human)
The University of Tennessee Research Foundation

US Patent
LigandPNGBDBM181242(US9139546, 39)
Affinity DataKi:  42.0nM ΔG°:  -42.8kJ/moleT: 2°CAssay Description:8 ug of membranes (20 ul of 1:8 dilution in incubation buffer) was incubated with 5 ul of drug solution (10E-4M to 10E-12M) and 5ul of 5.4 nM [3H]CP5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2016
Entry Details
Go to US Patent

TargetCannabinoid receptor 1(Human)
The University of Tennessee Research Foundation

US Patent
LigandPNGBDBM181243(US9139546, 40)
Affinity DataKi:  46.7nM ΔG°:  -42.5kJ/moleT: 2°CAssay Description:8 ug of membranes (20 ul of 1:8 dilution in incubation buffer) was incubated with 5 ul of drug solution (10E-4M to 10E-12M) and 5ul of 5.4 nM [3H]CP5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2016
Entry Details
Go to US Patent

TargetCannabinoid receptor 2(Human)
The University of Tennessee Research Foundation

US Patent
LigandPNGBDBM181245(US9139546, 43)
Affinity DataKi:  82.0nM ΔG°:  -41.1kJ/moleT: 2°CAssay Description:15.3 ug of membranes (20 ul of 1:20 dilution in incubation buffer) was incubated with 5 ul of drug solution (10E-4M to 10E-12M) and 5ul of 5.4 nM [3H...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2016
Entry Details
Go to US Patent

TargetCannabinoid receptor 1(Human)
The University of Tennessee Research Foundation

US Patent
LigandPNGBDBM50248606(3',5'-dichloro-4-(2-phenylpropan-2-yl)biphenyl-2,6...)
Affinity DataKi:  93.7nM ΔG°:  -40.8kJ/moleT: 2°CAssay Description:8 ug of membranes (20 ul of 1:8 dilution in incubation buffer) was incubated with 5 ul of drug solution (10E-4M to 10E-12M) and 5ul of 5.4 nM [3H]CP5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2016
Entry Details
Go to US Patent

TargetCannabinoid receptor 2(Human)
The University of Tennessee Research Foundation

US Patent
LigandPNGBDBM181239(US9139546, 26)
Affinity DataKi:  159nM ΔG°:  -39.5kJ/moleT: 2°CAssay Description:15.3 ug of membranes (20 ul of 1:20 dilution in incubation buffer) was incubated with 5 ul of drug solution (10E-4M to 10E-12M) and 5ul of 5.4 nM [3H...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2016
Entry Details
Go to US Patent

TargetCannabinoid receptor 1(Human)
The University of Tennessee Research Foundation

US Patent
LigandPNGBDBM181244(US9139546, 42)
Affinity DataKi:  199nM ΔG°:  -38.9kJ/moleT: 2°CAssay Description:8 ug of membranes (20 ul of 1:8 dilution in incubation buffer) was incubated with 5 ul of drug solution (10E-4M to 10E-12M) and 5ul of 5.4 nM [3H]CP5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2016
Entry Details
Go to US Patent

TargetCannabinoid receptor 2(Human)
The University of Tennessee Research Foundation

US Patent
LigandPNGBDBM181240(US9139546, 27)
Affinity DataKi:  225nM ΔG°:  -38.6kJ/moleT: 2°CAssay Description:15.3 ug of membranes (20 ul of 1:20 dilution in incubation buffer) was incubated with 5 ul of drug solution (10E-4M to 10E-12M) and 5ul of 5.4 nM [3H...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2016
Entry Details
Go to US Patent

TargetCannabinoid receptor 2(Human)
The University of Tennessee Research Foundation

US Patent
LigandPNGBDBM181238(US9139546, 25)
Affinity DataKi:  454nM ΔG°:  -36.8kJ/moleT: 2°CAssay Description:15.3 ug of membranes (20 ul of 1:20 dilution in incubation buffer) was incubated with 5 ul of drug solution (10E-4M to 10E-12M) and 5ul of 5.4 nM [3H...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2016
Entry Details
Go to US Patent

TargetCannabinoid receptor 1(Human)
The University of Tennessee Research Foundation

US Patent
LigandPNGBDBM50312841([11C](3',5'-dichloro-2-hydroxy-6-methoxybiphenyl-4...)
Affinity DataKi:  503nM ΔG°:  -36.6kJ/moleT: 2°CAssay Description:8 ug of membranes (20 ul of 1:8 dilution in incubation buffer) was incubated with 5 ul of drug solution (10E-4M to 10E-12M) and 5ul of 5.4 nM [3H]CP5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2016
Entry Details
Go to US Patent

TargetCannabinoid receptor 1(Human)
The University of Tennessee Research Foundation

US Patent
LigandPNGBDBM181239(US9139546, 26)
Affinity DataKi:  983nM ΔG°:  -34.9kJ/moleT: 2°CAssay Description:8 ug of membranes (20 ul of 1:8 dilution in incubation buffer) was incubated with 5 ul of drug solution (10E-4M to 10E-12M) and 5ul of 5.4 nM [3H]CP5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2016
Entry Details
Go to US Patent

TargetCannabinoid receptor 1(Human)
The University of Tennessee Research Foundation

US Patent
LigandPNGBDBM181241(US9139546, 31)
Affinity DataKi: >1.00E+3nM ΔG°: >-34.8kJ/moleT: 2°CAssay Description:8 ug of membranes (20 ul of 1:8 dilution in incubation buffer) was incubated with 5 ul of drug solution (10E-4M to 10E-12M) and 5ul of 5.4 nM [3H]CP5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2016
Entry Details
Go to US Patent

TargetCannabinoid receptor 1(Human)
The University of Tennessee Research Foundation

US Patent
LigandPNGBDBM50248605((3',5'-dichloro-2-hydroxy-6-methoxybiphenyl-4-yl)(...)
Affinity DataKi: >1.00E+3nM ΔG°: >-34.8kJ/moleT: 2°CAssay Description:8 ug of membranes (20 ul of 1:8 dilution in incubation buffer) was incubated with 5 ul of drug solution (10E-4M to 10E-12M) and 5ul of 5.4 nM [3H]CP5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2016
Entry Details
Go to US Patent

TargetCannabinoid receptor 1(Human)
The University of Tennessee Research Foundation

US Patent
LigandPNGBDBM181240(US9139546, 27)
Affinity DataKi: >1.00E+3nM ΔG°: >-34.8kJ/moleT: 2°CAssay Description:8 ug of membranes (20 ul of 1:8 dilution in incubation buffer) was incubated with 5 ul of drug solution (10E-4M to 10E-12M) and 5ul of 5.4 nM [3H]CP5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2016
Entry Details
Go to US Patent

TargetCannabinoid receptor 1(Human)
The University of Tennessee Research Foundation

US Patent
LigandPNGBDBM181238(US9139546, 25)
Affinity DataKi: >1.00E+3nM ΔG°: >-34.8kJ/moleT: 2°CAssay Description:8 ug of membranes (20 ul of 1:8 dilution in incubation buffer) was incubated with 5 ul of drug solution (10E-4M to 10E-12M) and 5ul of 5.4 nM [3H]CP5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2016
Entry Details
Go to US Patent

TargetCannabinoid receptor 1(Human)
The University of Tennessee Research Foundation

US Patent
LigandPNGBDBM50312840([11C](3',5'-dichloro-2,6-dimethoxybiphenyl-4-yl)(t...)
Affinity DataKi: >1.00E+3nM ΔG°: >-34.8kJ/moleT: 2°CAssay Description:8 ug of membranes (20 ul of 1:8 dilution in incubation buffer) was incubated with 5 ul of drug solution (10E-4M to 10E-12M) and 5ul of 5.4 nM [3H]CP5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2016
Entry Details
Go to US Patent

TargetCannabinoid receptor 1(Human)
The University of Tennessee Research Foundation

US Patent
LigandPNGBDBM50248603((3',5'-dichloro-2,6-dimethoxybiphenyl-4-yl)(phenyl...)
Affinity DataKi: >1.00E+3nM ΔG°: >-34.8kJ/moleT: 2°CAssay Description:8 ug of membranes (20 ul of 1:8 dilution in incubation buffer) was incubated with 5 ul of drug solution (10E-4M to 10E-12M) and 5ul of 5.4 nM [3H]CP5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2016
Entry Details
Go to US Patent