Compile Data Set for Download or QSAR
Report error Found 27 Enz. Inhib. hit(s) with all data for entry = 7291
TargetStearoyl-CoA desaturase(Human)
Merck Canada

US Patent
LigandChemical structure of BindingDB Monomer ID 186596BDBM186596(US9168248, 28)
Affinity DataIC50: 1nMpH: 7.5Assay Description:The potency of compounds of formula I against the stearoyl-CoA desaturase was determined by measuring the conversion of radiolabeled stearoyl-CoA to ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/18/2016
Entry Details
US Patent

TargetStearoyl-CoA desaturase(Human)
Merck Canada

US Patent
LigandChemical structure of BindingDB Monomer ID 186595BDBM186595(US9168248, 22)
Affinity DataIC50: 1nMpH: 7.5Assay Description:The potency of compounds of formula I against the stearoyl-CoA desaturase was determined by measuring the conversion of radiolabeled stearoyl-CoA to ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/18/2016
Entry Details
US Patent

TargetStearoyl-CoA desaturase(Human)
Merck Canada

US Patent
LigandChemical structure of BindingDB Monomer ID 186597BDBM186597(US9168248, 42)
Affinity DataIC50: 1nMpH: 7.5Assay Description:The potency of compounds of formula I against the stearoyl-CoA desaturase was determined by measuring the conversion of radiolabeled stearoyl-CoA to ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/18/2016
Entry Details
US Patent

TargetStearoyl-CoA desaturase(Human)
Merck Canada

US Patent
LigandChemical structure of BindingDB Monomer ID 186592BDBM186592(US9168248, 16)
Affinity DataIC50: 1nMpH: 7.5Assay Description:The potency of compounds of formula I against the stearoyl-CoA desaturase was determined by measuring the conversion of radiolabeled stearoyl-CoA to ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/18/2016
Entry Details
US Patent

TargetStearoyl-CoA desaturase(Human)
Merck Canada

US Patent
LigandChemical structure of BindingDB Monomer ID 186594BDBM186594(US9168248, 18)
Affinity DataIC50: 1nMpH: 7.5Assay Description:The potency of compounds of formula I against the stearoyl-CoA desaturase was determined by measuring the conversion of radiolabeled stearoyl-CoA to ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/18/2016
Entry Details
US Patent

TargetStearoyl-CoA desaturase(Human)
Merck Canada

US Patent
LigandChemical structure of BindingDB Monomer ID 186593BDBM186593(US9168248, 17)
Affinity DataIC50: 1nMpH: 7.5Assay Description:The potency of compounds of formula I against the stearoyl-CoA desaturase was determined by measuring the conversion of radiolabeled stearoyl-CoA to ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/18/2016
Entry Details
US Patent

TargetStearoyl-CoA desaturase(Human)
Merck Canada

US Patent
LigandChemical structure of BindingDB Monomer ID 186603BDBM186603(US9168248, 76)
Affinity DataIC50: 1nMpH: 7.5Assay Description:The potency of compounds of formula I against the stearoyl-CoA desaturase was determined by measuring the conversion of radiolabeled stearoyl-CoA to ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/18/2016
Entry Details
US Patent

TargetStearoyl-CoA desaturase(Human)
Merck Canada

US Patent
LigandChemical structure of BindingDB Monomer ID 186602BDBM186602(US9168248, 75)
Affinity DataIC50: 1nMpH: 7.5Assay Description:The potency of compounds of formula I against the stearoyl-CoA desaturase was determined by measuring the conversion of radiolabeled stearoyl-CoA to ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/18/2016
Entry Details
US Patent

TargetStearoyl-CoA desaturase(Human)
Merck Canada

US Patent
LigandChemical structure of BindingDB Monomer ID 186600BDBM186600(US9168248, 68)
Affinity DataIC50: 3nMpH: 7.5Assay Description:The potency of compounds of formula I against the stearoyl-CoA desaturase was determined by measuring the conversion of radiolabeled stearoyl-CoA to ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/18/2016
Entry Details
US Patent

TargetStearoyl-CoA desaturase(Human)
Merck Canada

US Patent
LigandChemical structure of BindingDB Monomer ID 186577BDBM186577(US9168248, 1 | US9168248, 72)
Affinity DataIC50: 3nMpH: 7.5Assay Description:The potency of compounds of formula I against the stearoyl-CoA desaturase was determined by measuring the conversion of radiolabeled stearoyl-CoA to ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/18/2016
Entry Details
US Patent

TargetStearoyl-CoA desaturase(Human)
Merck Canada

US Patent
LigandChemical structure of BindingDB Monomer ID 186578BDBM186578(US9168248, 2)
Affinity DataIC50: 11nMpH: 7.5Assay Description:The potency of compounds of formula I against the stearoyl-CoA desaturase was determined by measuring the conversion of radiolabeled stearoyl-CoA to ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/18/2016
Entry Details
US Patent

TargetStearoyl-CoA desaturase(Human)
Merck Canada

US Patent
LigandChemical structure of BindingDB Monomer ID 186577BDBM186577(US9168248, 1 | US9168248, 72)
Affinity DataIC50: 12nMpH: 7.5Assay Description:The potency of compounds of formula I against the stearoyl-CoA desaturase was determined by measuring the conversion of radiolabeled stearoyl-CoA to ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/18/2016
Entry Details
US Patent

TargetStearoyl-CoA desaturase(Human)
Merck Canada

US Patent
LigandChemical structure of BindingDB Monomer ID 186590BDBM186590(US9168248, 14)
Affinity DataIC50: 12nMpH: 7.5Assay Description:The potency of compounds of formula I against the stearoyl-CoA desaturase was determined by measuring the conversion of radiolabeled stearoyl-CoA to ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/18/2016
Entry Details
US Patent

TargetStearoyl-CoA desaturase(Human)
Merck Canada

US Patent
LigandChemical structure of BindingDB Monomer ID 186579BDBM186579(US9168248, 3)
Affinity DataIC50: 13nMpH: 7.5Assay Description:The potency of compounds of formula I against the stearoyl-CoA desaturase was determined by measuring the conversion of radiolabeled stearoyl-CoA to ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/18/2016
Entry Details
US Patent

TargetStearoyl-CoA desaturase(Human)
Merck Canada

US Patent
LigandChemical structure of BindingDB Monomer ID 186587BDBM186587(US9168248, 11)
Affinity DataIC50: 13nMpH: 7.5Assay Description:The potency of compounds of formula I against the stearoyl-CoA desaturase was determined by measuring the conversion of radiolabeled stearoyl-CoA to ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/18/2016
Entry Details
US Patent

TargetStearoyl-CoA desaturase(Human)
Merck Canada

US Patent
LigandChemical structure of BindingDB Monomer ID 186591BDBM186591(US9168248, 15)
Affinity DataIC50: 17nMpH: 7.5Assay Description:The potency of compounds of formula I against the stearoyl-CoA desaturase was determined by measuring the conversion of radiolabeled stearoyl-CoA to ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/18/2016
Entry Details
US Patent

TargetStearoyl-CoA desaturase(Human)
Merck Canada

US Patent
LigandChemical structure of BindingDB Monomer ID 186598BDBM186598(US9168248, 46)
Affinity DataIC50: 21nMpH: 7.5Assay Description:The potency of compounds of formula I against the stearoyl-CoA desaturase was determined by measuring the conversion of radiolabeled stearoyl-CoA to ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/18/2016
Entry Details
US Patent

TargetStearoyl-CoA desaturase(Human)
Merck Canada

US Patent
LigandChemical structure of BindingDB Monomer ID 186589BDBM186589(US9168248, 13)
Affinity DataIC50: 24nMpH: 7.5Assay Description:The potency of compounds of formula I against the stearoyl-CoA desaturase was determined by measuring the conversion of radiolabeled stearoyl-CoA to ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/18/2016
Entry Details
US Patent

TargetStearoyl-CoA desaturase(Human)
Merck Canada

US Patent
LigandChemical structure of BindingDB Monomer ID 186580BDBM186580(US9168248, 4)
Affinity DataIC50: 41nMpH: 7.5Assay Description:The potency of compounds of formula I against the stearoyl-CoA desaturase was determined by measuring the conversion of radiolabeled stearoyl-CoA to ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/18/2016
Entry Details
US Patent

TargetStearoyl-CoA desaturase(Human)
Merck Canada

US Patent
LigandChemical structure of BindingDB Monomer ID 186581BDBM186581(US9168248, 5)
Affinity DataIC50: 49nMpH: 7.5Assay Description:The potency of compounds of formula I against the stearoyl-CoA desaturase was determined by measuring the conversion of radiolabeled stearoyl-CoA to ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/18/2016
Entry Details
US Patent

TargetStearoyl-CoA desaturase(Human)
Merck Canada

US Patent
LigandChemical structure of BindingDB Monomer ID 186599BDBM186599(US9168248, 54)
Affinity DataIC50: 62nMpH: 7.5Assay Description:The potency of compounds of formula I against the stearoyl-CoA desaturase was determined by measuring the conversion of radiolabeled stearoyl-CoA to ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/18/2016
Entry Details
US Patent

TargetStearoyl-CoA desaturase(Human)
Merck Canada

US Patent
LigandChemical structure of BindingDB Monomer ID 186582BDBM186582(US9168248, 6)
Affinity DataIC50: 65nMpH: 7.5Assay Description:The potency of compounds of formula I against the stearoyl-CoA desaturase was determined by measuring the conversion of radiolabeled stearoyl-CoA to ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/18/2016
Entry Details
US Patent

TargetStearoyl-CoA desaturase(Human)
Merck Canada

US Patent
LigandChemical structure of BindingDB Monomer ID 186585BDBM186585(US9168248, 9)
Affinity DataIC50: 181nMpH: 7.5Assay Description:The potency of compounds of formula I against the stearoyl-CoA desaturase was determined by measuring the conversion of radiolabeled stearoyl-CoA to ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/18/2016
Entry Details
US Patent

TargetStearoyl-CoA desaturase(Human)
Merck Canada

US Patent
LigandChemical structure of BindingDB Monomer ID 186583BDBM186583(US9168248, 7)
Affinity DataIC50: 244nMpH: 7.5Assay Description:The potency of compounds of formula I against the stearoyl-CoA desaturase was determined by measuring the conversion of radiolabeled stearoyl-CoA to ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/18/2016
Entry Details
US Patent

TargetStearoyl-CoA desaturase(Human)
Merck Canada

US Patent
LigandChemical structure of BindingDB Monomer ID 186586BDBM186586(US9168248, 10)
Affinity DataIC50: 338nMpH: 7.5Assay Description:The potency of compounds of formula I against the stearoyl-CoA desaturase was determined by measuring the conversion of radiolabeled stearoyl-CoA to ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/18/2016
Entry Details
US Patent

TargetStearoyl-CoA desaturase(Human)
Merck Canada

US Patent
LigandChemical structure of BindingDB Monomer ID 186588BDBM186588(US9168248, 12)
Affinity DataIC50: 366nMpH: 7.5Assay Description:The potency of compounds of formula I against the stearoyl-CoA desaturase was determined by measuring the conversion of radiolabeled stearoyl-CoA to ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/18/2016
Entry Details
US Patent

TargetStearoyl-CoA desaturase(Human)
Merck Canada

US Patent
LigandChemical structure of BindingDB Monomer ID 186584BDBM186584(US9168248, 8)
Affinity DataIC50: 708nMpH: 7.5Assay Description:The potency of compounds of formula I against the stearoyl-CoA desaturase was determined by measuring the conversion of radiolabeled stearoyl-CoA to ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/18/2016
Entry Details
US Patent