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Found 6 Enz. Inhib. hit(s) with all data for entry = 7314
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM159345(US9034899, 36 | US9173879, 1 (-) - enantiomer | US...)
Affinity DataIC50:  1.80nMpH: 7.5 T: 2°CAssay Description:Compounds were dissolved in 100% DMSO at a concentration 100 times the desired highest assay concentration, serially diluted 1:3 in 100% DMSO, and 0....More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM159345(US9034899, 36 | US9173879, 1 (-) - enantiomer | US...)
Affinity DataIC50:  4.20nMpH: 7.5 T: 2°CAssay Description:Compounds were dissolved in 100% DMSO at a concentration 100 times the desired highest assay concentration, serially diluted 1:3 in 100% DMSO, and 0....More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM159345(US9034899, 36 | US9173879, 1 (-) - enantiomer | US...)
Affinity DataIC50:  4.80nMpH: 7.5 T: 2°CAssay Description:Compounds were dissolved in 100% DMSO at a concentration 100 times the desired highest assay concentration, serially diluted 1:3 in 100% DMSO, and 1....More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM159345(US9034899, 36 | US9173879, 1 (-) - enantiomer | US...)
Affinity DataIC50:  26nMpH: 7.5 T: 2°CAssay Description:Compounds were dissolved in 100% DMSO at a concentration 100 times the desired highest assay concentration, serially diluted 1:3 in 100% DMSO, and 1....More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM159345(US9034899, 36 | US9173879, 1 (-) - enantiomer | US...)
Affinity DataIC50:  30.8nMpH: 7.5 T: 2°CAssay Description:Compounds were dissolved in 100% DMSO at a concentration 100 times the desired highest assay concentration, serially diluted 1:3 in 100% DMSO, and 0....More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM159345(US9034899, 36 | US9173879, 1 (-) - enantiomer | US...)
Affinity DataIC50:  105nMpH: 7.5 T: 2°CAssay Description:Compounds were dissolved in 100% DMSO at a concentration 100 times the desired highest assay concentration, serially diluted 1:3 in 100% DMSO, and 0....More data for this Ligand-Target Pair
In DepthDetails US Patent