Compile Data Set for Download or QSAR
Report error Found 29 Enz. Inhib. hit(s) with all data for entry = 7317
TargetThyrotropin receptor(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 60862BDBM60862(BDBM189328 | US9174940, 32)
Affinity DataIC50: 12nMAssay Description:Antagonist activity of three test compounds against human TSI at the human TSH receptor was tested in Chinese Hamster Ovary (CHO) cells (cultured 16 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/2/2016
Entry Details
US Patent

TargetThyrotropin receptor(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 189329BDBM189329(US9174940, Compound C | (+)-(1-Acetyl-4-methyl-4-p...)
Affinity DataIC50: 47nMAssay Description:Antagonist activity of three test compounds against human TSI at the human TSH receptor was tested in Chinese Hamster Ovary (CHO) cells (cultured 16 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/2/2016
Entry Details
US Patent

TargetThyrotropin subunit beta(Bovine)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 60862BDBM60862(BDBM189328 | US9174940, 32)
Affinity DataIC50: 48nMAssay Description:Antagonist activity of three test compounds against human TSI at the human TSH receptor was tested in Chinese Hamster Ovary (CHO) cells (cultured 16 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/2/2016
Entry Details
US Patent

TargetThyrotropin receptor(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 189327BDBM189327(US9174940, Compound A | Hexanoic acid (Compound A))
Affinity DataIC50: 88nMAssay Description:Antagonist activity of three test compounds against human TSI at the human TSH receptor was tested in Chinese Hamster Ovary (CHO) cells (cultured 16 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/2/2016
Entry Details
US Patent

TargetThyrotropin receptor(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 60844BDBM60844(US9174940, 4)
Affinity DataIC50: 100nMAssay Description:Antagonist activity of three test compounds against human TSI at the human TSH receptor was tested in Chinese Hamster Ovary (CHO) cells (cultured 16 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/2/2016
Entry Details
US Patent

TargetThyrotropin receptor(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 60845BDBM60845(US9174940, 6)
Affinity DataIC50: 100nMAssay Description:Antagonist activity of three test compounds against human TSI at the human TSH receptor was tested in Chinese Hamster Ovary (CHO) cells (cultured 16 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/2/2016
Entry Details
US Patent

TargetThyrotropin receptor(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 60847BDBM60847(US9174940, 7)
Affinity DataIC50: 100nMAssay Description:Antagonist activity of three test compounds against human TSI at the human TSH receptor was tested in Chinese Hamster Ovary (CHO) cells (cultured 16 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/2/2016
Entry Details
US Patent

TargetThyrotropin receptor(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 60848BDBM60848(US9174940, 26 | US9174940, 11)
Affinity DataIC50: 100nMAssay Description:Antagonist activity of three test compounds against human TSI at the human TSH receptor was tested in Chinese Hamster Ovary (CHO) cells (cultured 16 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/2/2016
Entry Details
US Patent

TargetThyrotropin receptor(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 60843BDBM60843(US9174940, 1)
Affinity DataIC50: 100nMAssay Description:Antagonist activity of three test compounds against human TSI at the human TSH receptor was tested in Chinese Hamster Ovary (CHO) cells (cultured 16 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/2/2016
Entry Details
US Patent

TargetThyrotropin receptor(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 60853BDBM60853(US9174940, 27)
Affinity DataIC50: 100nMAssay Description:Antagonist activity of three test compounds against human TSI at the human TSH receptor was tested in Chinese Hamster Ovary (CHO) cells (cultured 16 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/2/2016
Entry Details
US Patent

TargetThyrotropin receptor(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 60855BDBM60855(US9174940, 28)
Affinity DataIC50: 100nMAssay Description:Antagonist activity of three test compounds against human TSI at the human TSH receptor was tested in Chinese Hamster Ovary (CHO) cells (cultured 16 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/2/2016
Entry Details
US Patent

TargetThyrotropin receptor(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 60856BDBM60856(US9174940, 29)
Affinity DataIC50: 100nMAssay Description:Antagonist activity of three test compounds against human TSI at the human TSH receptor was tested in Chinese Hamster Ovary (CHO) cells (cultured 16 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/2/2016
Entry Details
US Patent

TargetThyrotropin receptor(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 60857BDBM60857(US9174940, 30)
Affinity DataIC50: 100nMAssay Description:Antagonist activity of three test compounds against human TSI at the human TSH receptor was tested in Chinese Hamster Ovary (CHO) cells (cultured 16 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/2/2016
Entry Details
US Patent

TargetThyrotropin receptor(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 60849BDBM60849(US9174940, 12)
Affinity DataIC50: 100nMAssay Description:Antagonist activity of three test compounds against human TSI at the human TSH receptor was tested in Chinese Hamster Ovary (CHO) cells (cultured 16 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/2/2016
Entry Details
US Patent

TargetThyrotropin receptor(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 60850BDBM60850(US9174940, 13)
Affinity DataIC50: 100nMAssay Description:Antagonist activity of three test compounds against human TSI at the human TSH receptor was tested in Chinese Hamster Ovary (CHO) cells (cultured 16 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/2/2016
Entry Details
US Patent

TargetThyrotropin receptor(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 60851BDBM60851(US9174940, 18)
Affinity DataIC50: 100nMAssay Description:Antagonist activity of three test compounds against human TSI at the human TSH receptor was tested in Chinese Hamster Ovary (CHO) cells (cultured 16 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/2/2016
Entry Details
US Patent

TargetThyrotropin receptor(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 60848BDBM60848(US9174940, 26 | US9174940, 11)
Affinity DataIC50: 100nMAssay Description:Antagonist activity of three test compounds against human TSI at the human TSH receptor was tested in Chinese Hamster Ovary (CHO) cells (cultured 16 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/2/2016
Entry Details
US Patent

TargetThyrotropin receptor(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 60865BDBM60865(US9174940, 35)
Affinity DataIC50: 100nMAssay Description:Antagonist activity of three test compounds against human TSI at the human TSH receptor was tested in Chinese Hamster Ovary (CHO) cells (cultured 16 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/2/2016
Entry Details
US Patent

TargetThyrotropin receptor(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 60866BDBM60866(US9174940, 36)
Affinity DataIC50: 100nMAssay Description:Antagonist activity of three test compounds against human TSI at the human TSH receptor was tested in Chinese Hamster Ovary (CHO) cells (cultured 16 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/2/2016
Entry Details
US Patent

TargetThyrotropin receptor(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 60867BDBM60867(US9174940, 37)
Affinity DataIC50: 100nMAssay Description:Antagonist activity of three test compounds against human TSI at the human TSH receptor was tested in Chinese Hamster Ovary (CHO) cells (cultured 16 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/2/2016
Entry Details
US Patent

TargetThyrotropin receptor(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 60869BDBM60869(US9174940, 38)
Affinity DataIC50: 100nMAssay Description:Antagonist activity of three test compounds against human TSI at the human TSH receptor was tested in Chinese Hamster Ovary (CHO) cells (cultured 16 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/2/2016
Entry Details
US Patent

TargetThyrotropin receptor(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 60860BDBM60860(US9174940, 31)
Affinity DataIC50: 100nMAssay Description:Antagonist activity of three test compounds against human TSI at the human TSH receptor was tested in Chinese Hamster Ovary (CHO) cells (cultured 16 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/2/2016
Entry Details
US Patent

TargetThyrotropin receptor(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 60862BDBM60862(BDBM189328 | US9174940, 32)
Affinity DataIC50: 100nMAssay Description:Antagonist activity of three test compounds against human TSI at the human TSH receptor was tested in Chinese Hamster Ovary (CHO) cells (cultured 16 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/2/2016
Entry Details
US Patent

TargetThyrotropin receptor(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 60863BDBM60863(US9174940, 33)
Affinity DataIC50: 100nMAssay Description:Antagonist activity of three test compounds against human TSI at the human TSH receptor was tested in Chinese Hamster Ovary (CHO) cells (cultured 16 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/2/2016
Entry Details
US Patent

TargetThyrotropin receptor(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 60864BDBM60864(US9174940, 34)
Affinity DataIC50: 100nMAssay Description:Antagonist activity of three test compounds against human TSI at the human TSH receptor was tested in Chinese Hamster Ovary (CHO) cells (cultured 16 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/2/2016
Entry Details
US Patent

TargetThyrotropin receptor(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 60870BDBM60870(US9174940, 39)
Affinity DataIC50: 100nMAssay Description:Antagonist activity of three test compounds against human TSI at the human TSH receptor was tested in Chinese Hamster Ovary (CHO) cells (cultured 16 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/2/2016
Entry Details
US Patent

TargetThyrotropin receptor(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 60872BDBM60872(US9174940, 40)
Affinity DataIC50: 100nMAssay Description:Antagonist activity of three test compounds against human TSI at the human TSH receptor was tested in Chinese Hamster Ovary (CHO) cells (cultured 16 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/2/2016
Entry Details
US Patent

TargetThyrotropin subunit beta(Bovine)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 189329BDBM189329(US9174940, Compound C | (+)-(1-Acetyl-4-methyl-4-p...)
Affinity DataIC50: 192nMAssay Description:Antagonist activity of three test compounds against human TSI at the human TSH receptor was tested in Chinese Hamster Ovary (CHO) cells (cultured 16 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/2/2016
Entry Details
US Patent

TargetThyrotropin subunit beta(Bovine)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 189327BDBM189327(US9174940, Compound A | Hexanoic acid (Compound A))
Affinity DataIC50: 368nMAssay Description:Antagonist activity of three test compounds against human TSI at the human TSH receptor was tested in Chinese Hamster Ovary (CHO) cells (cultured 16 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/2/2016
Entry Details
US Patent