Compile Data Set for Download or QSAR
Report error Found 256 Enz. Inhib. hit(s) with all data for entry = 7336
LigandChemical structure of BindingDB Monomer ID 190202BDBM190202(US9175331, 32 | EPZ008337 | US12390472, Example EP...)
Affinity DataIC50: 0.800nMAssay Description:Test compounds were serially diluted 3-fold in DMSO in a 10 point-curve and 1 uL was spotted into a 384-well microplate in duplicate using a Platemat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/8/2016
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 172176BDBM172176(US9175331, 61 | US9090562, 184 | EPZ009161 | US101...)
Affinity DataIC50: 0.800nMAssay Description:Test compounds were serially diluted 3-fold in DMSO in a 10 point-curve and 1 uL was spotted into a 384-well microplate in duplicate using a Platemat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/8/2016
Entry Details
US Patent

TargetHistone-lysine N-methyltransferase EZH2(Human)
Epizyme

US Patent
LigandChemical structure of BindingDB Monomer ID 172176BDBM172176(US9175331, 61 | US9090562, 184 | EPZ009161 | US101...)
Affinity DataIC50: 0.900nMAssay Description:Test compounds were serially diluted 3-fold in DMSO in a 10 point-curve and 1 uL was spotted into a 384-well microplate in duplicate using a Platemat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/8/2016
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 172176BDBM172176(US9175331, 61 | US9090562, 184 | EPZ009161 | US101...)
Affinity DataIC50: 1.10nMAssay Description:Test compounds were serially diluted 3-fold in DMSO in a 10 point-curve and 1 uL was spotted into a 384-well microplate in duplicate using a Platemat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/8/2016
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 190201BDBM190201(US9175331, 31 | EPZ008336)
Affinity DataIC50: 1.30nMAssay Description:Test compounds were serially diluted 3-fold in DMSO in a 10 point-curve and 1 uL was spotted into a 384-well microplate in duplicate using a Platemat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/8/2016
Entry Details
US Patent

TargetHistone-lysine N-methyltransferase EZH2(Human)
Epizyme

US Patent
LigandChemical structure of BindingDB Monomer ID 172138BDBM172138(US9175331, 16 | US9090562, 145 | EPZ007428 | US101...)
Affinity DataIC50: 1.40nMAssay Description:Test compounds were serially diluted 3-fold in DMSO in a 10 point-curve and 1 uL was spotted into a 384-well microplate in duplicate using a Platemat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/8/2016
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 190202BDBM190202(US9175331, 32 | EPZ008337 | US12390472, Example EP...)
Affinity DataIC50: 1.40nMAssay Description:Test compounds were serially diluted 3-fold in DMSO in a 10 point-curve and 1 uL was spotted into a 384-well microplate in duplicate using a Platemat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/8/2016
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 190204BDBM190204(US9175331, 35 | EPZ008491)
Affinity DataIC50: 1.40nMAssay Description:Test compounds were serially diluted 3-fold in DMSO in a 10 point-curve and 1 uL was spotted into a 384-well microplate in duplicate using a Platemat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/8/2016
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 190202BDBM190202(US9175331, 32 | EPZ008337 | US12390472, Example EP...)
Affinity DataIC50: 1.5nMAssay Description:Test compounds were serially diluted 3-fold in DMSO in a 10 point-curve and 1 uL was spotted into a 384-well microplate in duplicate using a Platemat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/8/2016
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 172174BDBM172174(US9175331, 44 | US9090562, 182 | EPZ008681 | US101...)
Affinity DataIC50: 1.5nMAssay Description:Test compounds were serially diluted 3-fold in DMSO in a 10 point-curve and 1 uL was spotted into a 384-well microplate in duplicate using a Platemat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/8/2016
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 190200BDBM190200(US9175331, 30 | EPZ008335)
Affinity DataIC50: 1.5nMAssay Description:Test compounds were serially diluted 3-fold in DMSO in a 10 point-curve and 1 uL was spotted into a 384-well microplate in duplicate using a Platemat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/8/2016
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 190199BDBM190199(US9175331, 29 | EPZ008286)
Affinity DataIC50: 1.5nMAssay Description:Test compounds were serially diluted 3-fold in DMSO in a 10 point-curve and 1 uL was spotted into a 384-well microplate in duplicate using a Platemat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/8/2016
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 172038BDBM172038(US10647700, Compound EPZ6438 | BDBM190183 | US1015...)
Affinity DataIC50: 1.5nMAssay Description:Test compounds were serially diluted 3-fold in DMSO in a 10 point-curve and 1 uL was spotted into a 384-well microplate in duplicate using a Platemat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/8/2016
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 190223BDBM190223(US9175331, 60 | EPZ009158)
Affinity DataIC50: 1.60nMAssay Description:Test compounds were serially diluted 3-fold in DMSO in a 10 point-curve and 1 uL was spotted into a 384-well microplate in duplicate using a Platemat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/8/2016
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 190211BDBM190211(US9175331, 47 | EPZ008990)
Affinity DataIC50: 1.60nMAssay Description:Test compounds were serially diluted 3-fold in DMSO in a 10 point-curve and 1 uL was spotted into a 384-well microplate in duplicate using a Platemat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/8/2016
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 190203BDBM190203(US9175331, 34 | EPZ008344)
Affinity DataIC50: 1.60nMAssay Description:Test compounds were serially diluted 3-fold in DMSO in a 10 point-curve and 1 uL was spotted into a 384-well microplate in duplicate using a Platemat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/8/2016
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 190211BDBM190211(US9175331, 47 | EPZ008990)
Affinity DataIC50: 1.70nMAssay Description:Test compounds were serially diluted 3-fold in DMSO in a 10 point-curve and 1 uL was spotted into a 384-well microplate in duplicate using a Platemat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/8/2016
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 190199BDBM190199(US9175331, 29 | EPZ008286)
Affinity DataIC50: 1.80nMAssay Description:Test compounds were serially diluted 3-fold in DMSO in a 10 point-curve and 1 uL was spotted into a 384-well microplate in duplicate using a Platemat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/8/2016
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 172138BDBM172138(US9175331, 16 | US9090562, 145 | EPZ007428 | US101...)
Affinity DataIC50: 1.90nMAssay Description:Test compounds were serially diluted 3-fold in DMSO in a 10 point-curve and 1 uL was spotted into a 384-well microplate in duplicate using a Platemat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/8/2016
Entry Details
US Patent

TargetHistone-lysine N-methyltransferase EZH2(Human)
Epizyme

US Patent
LigandChemical structure of BindingDB Monomer ID 190223BDBM190223(US9175331, 60 | EPZ009158)
Affinity DataIC50: 2.10nMAssay Description:Test compounds were serially diluted 3-fold in DMSO in a 10 point-curve and 1 uL was spotted into a 384-well microplate in duplicate using a Platemat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/8/2016
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 172138BDBM172138(US9175331, 16 | US9090562, 145 | EPZ007428 | US101...)
Affinity DataIC50: 2.10nMAssay Description:Test compounds were serially diluted 3-fold in DMSO in a 10 point-curve and 1 uL was spotted into a 384-well microplate in duplicate using a Platemat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/8/2016
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 190198BDBM190198(US9175331, 27 | EPZ008279)
Affinity DataIC50: 2.20nMAssay Description:Test compounds were serially diluted 3-fold in DMSO in a 10 point-curve and 1 uL was spotted into a 384-well microplate in duplicate using a Platemat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/8/2016
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 190210BDBM190210(US9175331, 46 | EPZ008989)
Affinity DataIC50: 2.20nMAssay Description:Test compounds were serially diluted 3-fold in DMSO in a 10 point-curve and 1 uL was spotted into a 384-well microplate in duplicate using a Platemat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/8/2016
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 172038BDBM172038(US10647700, Compound EPZ6438 | BDBM190183 | US1015...)
Affinity DataIC50: 2.20nMAssay Description:Test compounds were serially diluted 3-fold in DMSO in a 10 point-curve and 1 uL was spotted into a 384-well microplate in duplicate using a Platemat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/8/2016
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 190196BDBM190196(US9175331, 25 | EPZ008277)
Affinity DataIC50: 2.30nMAssay Description:Test compounds were serially diluted 3-fold in DMSO in a 10 point-curve and 1 uL was spotted into a 384-well microplate in duplicate using a Platemat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/8/2016
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 190201BDBM190201(US9175331, 31 | EPZ008336)
Affinity DataIC50: 2.40nMAssay Description:Test compounds were serially diluted 3-fold in DMSO in a 10 point-curve and 1 uL was spotted into a 384-well microplate in duplicate using a Platemat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/8/2016
Entry Details
US Patent

TargetHistone-lysine N-methyltransferase EZH2(Human)
Epizyme

US Patent
LigandChemical structure of BindingDB Monomer ID 172081BDBM172081(BDBM190184 | US10155002, Compound 87 | US9090562, ...)
Affinity DataIC50: 2.5nMAssay Description:Test compounds were serially diluted 3-fold in DMSO in a 10 point-curve and 1 uL was spotted into a 384-well microplate in duplicate using a Platemat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/8/2016
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 190199BDBM190199(US9175331, 29 | EPZ008286)
Affinity DataIC50: 2.5nMAssay Description:Test compounds were serially diluted 3-fold in DMSO in a 10 point-curve and 1 uL was spotted into a 384-well microplate in duplicate using a Platemat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/8/2016
Entry Details
US Patent

TargetHistone-lysine N-methyltransferase EZH2(Human)
Epizyme

US Patent
LigandChemical structure of BindingDB Monomer ID 190190BDBM190190(US9175331, 18 | EPZ007648)
Affinity DataIC50: 2.5nMAssay Description:Test compounds were serially diluted 3-fold in DMSO in a 10 point-curve and 1 uL was spotted into a 384-well microplate in duplicate using a Platemat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/8/2016
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 172174BDBM172174(US9175331, 44 | US9090562, 182 | EPZ008681 | US101...)
Affinity DataIC50: 2.70nMAssay Description:Test compounds were serially diluted 3-fold in DMSO in a 10 point-curve and 1 uL was spotted into a 384-well microplate in duplicate using a Platemat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/8/2016
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 190223BDBM190223(US9175331, 60 | EPZ009158)
Affinity DataIC50: 2.70nMAssay Description:Test compounds were serially diluted 3-fold in DMSO in a 10 point-curve and 1 uL was spotted into a 384-well microplate in duplicate using a Platemat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/8/2016
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 190223BDBM190223(US9175331, 60 | EPZ009158)
Affinity DataIC50: 2.70nMAssay Description:Test compounds were serially diluted 3-fold in DMSO in a 10 point-curve and 1 uL was spotted into a 384-well microplate in duplicate using a Platemat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/8/2016
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 190206BDBM190206(US9175331, 37 | EPZ008494)
Affinity DataIC50: 2.80nMAssay Description:Test compounds were serially diluted 3-fold in DMSO in a 10 point-curve and 1 uL was spotted into a 384-well microplate in duplicate using a Platemat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/8/2016
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 172166BDBM172166(US9175331, 28 | US9090562, 174 | EPZ008280 | US101...)
Affinity DataIC50: 2.80nMAssay Description:Test compounds were serially diluted 3-fold in DMSO in a 10 point-curve and 1 uL was spotted into a 384-well microplate in duplicate using a Platemat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/8/2016
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 190210BDBM190210(US9175331, 46 | EPZ008989)
Affinity DataIC50: 2.80nMAssay Description:Test compounds were serially diluted 3-fold in DMSO in a 10 point-curve and 1 uL was spotted into a 384-well microplate in duplicate using a Platemat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/8/2016
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 190204BDBM190204(US9175331, 35 | EPZ008491)
Affinity DataIC50: 2.90nMAssay Description:Test compounds were serially diluted 3-fold in DMSO in a 10 point-curve and 1 uL was spotted into a 384-well microplate in duplicate using a Platemat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/8/2016
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 190217BDBM190217(US9175331, 54 | EPZ009152)
Affinity DataIC50: 2.90nMAssay Description:Test compounds were serially diluted 3-fold in DMSO in a 10 point-curve and 1 uL was spotted into a 384-well microplate in duplicate using a Platemat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/8/2016
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 172166BDBM172166(US9175331, 28 | US9090562, 174 | EPZ008280 | US101...)
Affinity DataIC50: 2.90nMAssay Description:Test compounds were serially diluted 3-fold in DMSO in a 10 point-curve and 1 uL was spotted into a 384-well microplate in duplicate using a Platemat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/8/2016
Entry Details
US Patent

TargetHistone-lysine N-methyltransferase EZH2(Human)
Epizyme

US Patent
LigandChemical structure of BindingDB Monomer ID 172174BDBM172174(US9175331, 44 | US9090562, 182 | EPZ008681 | US101...)
Affinity DataIC50: 2.90nMAssay Description:Test compounds were serially diluted 3-fold in DMSO in a 10 point-curve and 1 uL was spotted into a 384-well microplate in duplicate using a Platemat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/8/2016
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 190204BDBM190204(US9175331, 35 | EPZ008491)
Affinity DataIC50: 2.90nMAssay Description:Test compounds were serially diluted 3-fold in DMSO in a 10 point-curve and 1 uL was spotted into a 384-well microplate in duplicate using a Platemat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/8/2016
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 190200BDBM190200(US9175331, 30 | EPZ008335)
Affinity DataIC50: 2.90nMAssay Description:Test compounds were serially diluted 3-fold in DMSO in a 10 point-curve and 1 uL was spotted into a 384-well microplate in duplicate using a Platemat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/8/2016
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 190208BDBM190208(US9175331, 43 | EPZ008630)
Affinity DataIC50: 2.90nMAssay Description:Test compounds were serially diluted 3-fold in DMSO in a 10 point-curve and 1 uL was spotted into a 384-well microplate in duplicate using a Platemat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/8/2016
Entry Details
US Patent

TargetHistone-lysine N-methyltransferase EZH2(Human)
Epizyme

US Patent
LigandChemical structure of BindingDB Monomer ID 190217BDBM190217(US9175331, 54 | EPZ009152)
Affinity DataIC50: 3nMAssay Description:Test compounds were serially diluted 3-fold in DMSO in a 10 point-curve and 1 uL was spotted into a 384-well microplate in duplicate using a Platemat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/8/2016
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 172167BDBM172167(US9175331, 33 | US9090562, 175 | EPZ008338 | US101...)
Affinity DataIC50: 3.10nMAssay Description:Test compounds were serially diluted 3-fold in DMSO in a 10 point-curve and 1 uL was spotted into a 384-well microplate in duplicate using a Platemat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/8/2016
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 190217BDBM190217(US9175331, 54 | EPZ009152)
Affinity DataIC50: 3.10nMAssay Description:Test compounds were serially diluted 3-fold in DMSO in a 10 point-curve and 1 uL was spotted into a 384-well microplate in duplicate using a Platemat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/8/2016
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 172081BDBM172081(BDBM190184 | US10155002, Compound 87 | US9090562, ...)
Affinity DataIC50: 3.20nMAssay Description:Test compounds were serially diluted 3-fold in DMSO in a 10 point-curve and 1 uL was spotted into a 384-well microplate in duplicate using a Platemat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/8/2016
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 190218BDBM190218(US9175331, 55 | EPZ009153)
Affinity DataIC50: 3.20nMAssay Description:Test compounds were serially diluted 3-fold in DMSO in a 10 point-curve and 1 uL was spotted into a 384-well microplate in duplicate using a Platemat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/8/2016
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 190185BDBM190185(US9175331, 11 | EPZ007038)
Affinity DataIC50: 3.20nMAssay Description:Test compounds were serially diluted 3-fold in DMSO in a 10 point-curve and 1 uL was spotted into a 384-well microplate in duplicate using a Platemat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/8/2016
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 190208BDBM190208(US9175331, 43 | EPZ008630)
Affinity DataIC50: 3.20nMAssay Description:Test compounds were serially diluted 3-fold in DMSO in a 10 point-curve and 1 uL was spotted into a 384-well microplate in duplicate using a Platemat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/8/2016
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 190217BDBM190217(US9175331, 54 | EPZ009152)
Affinity DataIC50: 3.30nMAssay Description:Test compounds were serially diluted 3-fold in DMSO in a 10 point-curve and 1 uL was spotted into a 384-well microplate in duplicate using a Platemat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/8/2016
Entry Details
US Patent

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