Compile Data Set for Download or QSAR
Report error Found 47 Enz. Inhib. hit(s) with all data for entry = 7366
TargetSerine protease hepsin(Human)
Fred Hutchinson Cancer Research Center

US Patent
LigandChemical structure of BindingDB Monomer ID 50041802BDBM50041802(CHEMBL46469 | 1,8-dihydroxyanthrone | 1,8-dihydrox...)
Affinity DataIC50: 230nMAssay Description:To identify novel inhibitors of hepsin, the Chembridge DIVERSet 10,000 compound high-diversity library was screened using an assay based on the cleav...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/6/2016
Entry Details
US Patent

TargetSerine protease hepsin(Human)
Fred Hutchinson Cancer Research Center

US Patent
LigandChemical structure of BindingDB Monomer ID 123129BDBM123129(CID236790 | 1-(3-nitro-phenyl)-pyrrole-2,5-dione (...)
Affinity DataIC50: 280nMAssay Description:To identify novel inhibitors of hepsin, the Chembridge DIVERSet 10,000 compound high-diversity library was screened using an assay based on the cleav...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/6/2016
Entry Details
US Patent

TargetSerine protease hepsin(Human)
Fred Hutchinson Cancer Research Center

US Patent
LigandChemical structure of BindingDB Monomer ID 191639BDBM191639(US9182402, 12)
Affinity DataIC50: 330nMAssay Description:To identify novel inhibitors of hepsin, the Chembridge DIVERSet 10,000 compound high-diversity library was screened using an assay based on the cleav...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/6/2016
Entry Details
US Patent

TargetSerine protease hepsin(Human)
Fred Hutchinson Cancer Research Center

US Patent
LigandChemical structure of BindingDB Monomer ID 50069104BDBM50069104(CHEMBL1449583 | US9182402, 4)
Affinity DataIC50: 350nMAssay Description:To identify novel inhibitors of hepsin, the Chembridge DIVERSet 10,000 compound high-diversity library was screened using an assay based on the cleav...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/6/2016
Entry Details
US Patent

TargetSerine protease hepsin(Human)
Fred Hutchinson Cancer Research Center

US Patent
LigandChemical structure of BindingDB Monomer ID 50007260BDBM50007260(2,6-di-tert-butyl-4-(2-(3,5-di-tert-butyl-4-hydrox...)
Affinity DataIC50: 430nMAssay Description:To identify novel inhibitors of hepsin, the Chembridge DIVERSet 10,000 compound high-diversity library was screened using an assay based on the cleav...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/6/2016
Entry Details
US Patent

TargetSerine protease hepsin(Human)
Fred Hutchinson Cancer Research Center

US Patent
LigandChemical structure of BindingDB Monomer ID 191631BDBM191631(US9182402, 5)
Affinity DataIC50: 570nMAssay Description:To identify novel inhibitors of hepsin, the Chembridge DIVERSet 10,000 compound high-diversity library was screened using an assay based on the cleav...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/6/2016
Entry Details
US Patent

TargetSerine protease hepsin(Human)
Fred Hutchinson Cancer Research Center

US Patent
LigandChemical structure of BindingDB Monomer ID 191635BDBM191635(US9182402, 8)
Affinity DataIC50: 720nMAssay Description:To identify novel inhibitors of hepsin, the Chembridge DIVERSet 10,000 compound high-diversity library was screened using an assay based on the cleav...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/6/2016
Entry Details
US Patent

TargetSerine protease hepsin(Human)
Fred Hutchinson Cancer Research Center

US Patent
LigandChemical structure of BindingDB Monomer ID 50013876BDBM50013876(N-Methyl-D-aspartate | N-Methyl aspartic acid | CH...)
Affinity DataIC50: 750nMAssay Description:To identify novel inhibitors of hepsin, the Chembridge DIVERSet 10,000 compound high-diversity library was screened using an assay based on the cleav...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/6/2016
Entry Details
US Patent

TargetSerine protease hepsin(Human)
Fred Hutchinson Cancer Research Center

US Patent
LigandChemical structure of BindingDB Monomer ID 191632BDBM191632(US9182402, 2)
Affinity DataIC50: 760nMAssay Description:To identify novel inhibitors of hepsin, the Chembridge DIVERSet 10,000 compound high-diversity library was screened using an assay based on the cleav...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/6/2016
Entry Details
US Patent

TargetSerine protease hepsin(Human)
Fred Hutchinson Cancer Research Center

US Patent
LigandChemical structure of BindingDB Monomer ID 191637BDBM191637(US9182402, 10)
Affinity DataIC50: 930nMAssay Description:To identify novel inhibitors of hepsin, the Chembridge DIVERSet 10,000 compound high-diversity library was screened using an assay based on the cleav...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/6/2016
Entry Details
US Patent

TargetSerine protease hepsin(Human)
Fred Hutchinson Cancer Research Center

US Patent
LigandChemical structure of BindingDB Monomer ID 191636BDBM191636(US9182402, 9)
Affinity DataIC50: 980nMAssay Description:To identify novel inhibitors of hepsin, the Chembridge DIVERSet 10,000 compound high-diversity library was screened using an assay based on the cleav...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/6/2016
Entry Details
US Patent

TargetSerine protease hepsin(Human)
Fred Hutchinson Cancer Research Center

US Patent
LigandChemical structure of BindingDB Monomer ID 191633BDBM191633(US9182402, 6)
Affinity DataIC50: 980nMAssay Description:To identify novel inhibitors of hepsin, the Chembridge DIVERSet 10,000 compound high-diversity library was screened using an assay based on the cleav...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/6/2016
Entry Details
US Patent

TargetTrypsin(Pig)
Fred Hutchinson Cancer Research Center

US Patent
LigandChemical structure of BindingDB Monomer ID 50041802BDBM50041802(CHEMBL46469 | 1,8-dihydroxyanthrone | 1,8-dihydrox...)
Affinity DataIC50: 1.26E+3nMAssay Description:To identify novel inhibitors of hepsin, the Chembridge DIVERSet 10,000 compound high-diversity library was screened using an assay based on the cleav...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/6/2016
Entry Details
US Patent

TargetSerine protease hepsin(Human)
Fred Hutchinson Cancer Research Center

US Patent
LigandChemical structure of BindingDB Monomer ID 191638BDBM191638(US9182402, 11)
Affinity DataIC50: 1.31E+3nMAssay Description:To identify novel inhibitors of hepsin, the Chembridge DIVERSet 10,000 compound high-diversity library was screened using an assay based on the cleav...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/6/2016
Entry Details
US Patent

TargetTrypsin(Pig)
Fred Hutchinson Cancer Research Center

US Patent
LigandChemical structure of BindingDB Monomer ID 191635BDBM191635(US9182402, 8)
Affinity DataIC50: 1.71E+3nMAssay Description:To identify novel inhibitors of hepsin, the Chembridge DIVERSet 10,000 compound high-diversity library was screened using an assay based on the cleav...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/6/2016
Entry Details
US Patent

TargetSerine protease hepsin(Human)
Fred Hutchinson Cancer Research Center

US Patent
LigandChemical structure of BindingDB Monomer ID 191630BDBM191630(US9182402, 3)
Affinity DataIC50: 1.93E+3nMAssay Description:To identify novel inhibitors of hepsin, the Chembridge DIVERSet 10,000 compound high-diversity library was screened using an assay based on the cleav...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/6/2016
Entry Details
US Patent

TargetTrypsin(Pig)
Fred Hutchinson Cancer Research Center

US Patent
LigandChemical structure of BindingDB Monomer ID 191638BDBM191638(US9182402, 11)
Affinity DataIC50: 2.00E+3nMAssay Description:To identify novel inhibitors of hepsin, the Chembridge DIVERSet 10,000 compound high-diversity library was screened using an assay based on the cleav...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/6/2016
Entry Details
US Patent

TargetSerine protease hepsin(Human)
Fred Hutchinson Cancer Research Center

US Patent
LigandChemical structure of BindingDB Monomer ID 81467BDBM81467(CHEMBL1085765 | NSC_4034 | CAS_569-65-3 | Meclizin...)
Affinity DataIC50: 2.02E+3nMAssay Description:To identify novel inhibitors of hepsin, the Chembridge DIVERSet 10,000 compound high-diversity library was screened using an assay based on the cleav...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/6/2016
Entry Details
US Patent

TargetSerine protease hepsin(Human)
Fred Hutchinson Cancer Research Center

US Patent
LigandChemical structure of BindingDB Monomer ID 191634BDBM191634(US9182402, 7)
Affinity DataIC50: 2.31E+3nMAssay Description:To identify novel inhibitors of hepsin, the Chembridge DIVERSet 10,000 compound high-diversity library was screened using an assay based on the cleav...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/6/2016
Entry Details
US Patent

TargetTrypsin(Pig)
Fred Hutchinson Cancer Research Center

US Patent
LigandChemical structure of BindingDB Monomer ID 50013876BDBM50013876(N-Methyl-D-aspartate | N-Methyl aspartic acid | CH...)
Affinity DataIC50: 2.42E+3nMAssay Description:To identify novel inhibitors of hepsin, the Chembridge DIVERSet 10,000 compound high-diversity library was screened using an assay based on the cleav...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/6/2016
Entry Details
US Patent

TargetTrypsin(Pig)
Fred Hutchinson Cancer Research Center

US Patent
LigandChemical structure of BindingDB Monomer ID 191639BDBM191639(US9182402, 12)
Affinity DataIC50: 3.50E+3nMAssay Description:To identify novel inhibitors of hepsin, the Chembridge DIVERSet 10,000 compound high-diversity library was screened using an assay based on the cleav...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/6/2016
Entry Details
US Patent

TargetTrypsin(Pig)
Fred Hutchinson Cancer Research Center

US Patent
LigandChemical structure of BindingDB Monomer ID 123129BDBM123129(CID236790 | 1-(3-nitro-phenyl)-pyrrole-2,5-dione (...)
Affinity DataIC50: 3.88E+3nMAssay Description:To identify novel inhibitors of hepsin, the Chembridge DIVERSet 10,000 compound high-diversity library was screened using an assay based on the cleav...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/6/2016
Entry Details
US Patent

TargetTrypsin(Pig)
Fred Hutchinson Cancer Research Center

US Patent
LigandChemical structure of BindingDB Monomer ID 191630BDBM191630(US9182402, 3)
Affinity DataIC50: 7.63E+3nMAssay Description:To identify novel inhibitors of hepsin, the Chembridge DIVERSet 10,000 compound high-diversity library was screened using an assay based on the cleav...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/6/2016
Entry Details
US Patent

TargetTrypsin(Pig)
Fred Hutchinson Cancer Research Center

US Patent
LigandChemical structure of BindingDB Monomer ID 191637BDBM191637(US9182402, 10)
Affinity DataIC50: 7.72E+3nMAssay Description:To identify novel inhibitors of hepsin, the Chembridge DIVERSet 10,000 compound high-diversity library was screened using an assay based on the cleav...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/6/2016
Entry Details
US Patent

TargetTrypsin(Pig)
Fred Hutchinson Cancer Research Center

US Patent
LigandChemical structure of BindingDB Monomer ID 191633BDBM191633(US9182402, 6)
Affinity DataIC50: 1.02E+4nMAssay Description:To identify novel inhibitors of hepsin, the Chembridge DIVERSet 10,000 compound high-diversity library was screened using an assay based on the cleav...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/6/2016
Entry Details
US Patent

TargetTrypsin(Pig)
Fred Hutchinson Cancer Research Center

US Patent
LigandChemical structure of BindingDB Monomer ID 191634BDBM191634(US9182402, 7)
Affinity DataIC50: 1.31E+4nMAssay Description:To identify novel inhibitors of hepsin, the Chembridge DIVERSet 10,000 compound high-diversity library was screened using an assay based on the cleav...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/6/2016
Entry Details
US Patent

TargetTrypsin(Pig)
Fred Hutchinson Cancer Research Center

US Patent
LigandChemical structure of BindingDB Monomer ID 50069104BDBM50069104(CHEMBL1449583 | US9182402, 4)
Affinity DataIC50: 1.96E+4nMAssay Description:To identify novel inhibitors of hepsin, the Chembridge DIVERSet 10,000 compound high-diversity library was screened using an assay based on the cleav...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/6/2016
Entry Details
US Patent

TargetProthrombin(Bovine)
Fred Hutchinson Cancer Research Center

US Patent
LigandChemical structure of BindingDB Monomer ID 191636BDBM191636(US9182402, 9)
Affinity DataIC50: 2.00E+4nMAssay Description:To identify novel inhibitors of hepsin, the Chembridge DIVERSet 10,000 compound high-diversity library was screened using an assay based on the cleav...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/6/2016
Entry Details
US Patent

TargetProthrombin(Bovine)
Fred Hutchinson Cancer Research Center

US Patent
LigandChemical structure of BindingDB Monomer ID 191635BDBM191635(US9182402, 8)
Affinity DataIC50: 2.00E+4nMAssay Description:To identify novel inhibitors of hepsin, the Chembridge DIVERSet 10,000 compound high-diversity library was screened using an assay based on the cleav...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/6/2016
Entry Details
US Patent

TargetProthrombin(Bovine)
Fred Hutchinson Cancer Research Center

US Patent
LigandChemical structure of BindingDB Monomer ID 191638BDBM191638(US9182402, 11)
Affinity DataIC50: 2.00E+4nMAssay Description:To identify novel inhibitors of hepsin, the Chembridge DIVERSet 10,000 compound high-diversity library was screened using an assay based on the cleav...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/6/2016
Entry Details
US Patent

TargetProthrombin(Bovine)
Fred Hutchinson Cancer Research Center

US Patent
LigandChemical structure of BindingDB Monomer ID 191637BDBM191637(US9182402, 10)
Affinity DataIC50: 2.00E+4nMAssay Description:To identify novel inhibitors of hepsin, the Chembridge DIVERSet 10,000 compound high-diversity library was screened using an assay based on the cleav...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/6/2016
Entry Details
US Patent

TargetProthrombin(Bovine)
Fred Hutchinson Cancer Research Center

US Patent
LigandChemical structure of BindingDB Monomer ID 191631BDBM191631(US9182402, 5)
Affinity DataIC50: 2.00E+4nMAssay Description:To identify novel inhibitors of hepsin, the Chembridge DIVERSet 10,000 compound high-diversity library was screened using an assay based on the cleav...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/6/2016
Entry Details
US Patent

TargetProthrombin(Bovine)
Fred Hutchinson Cancer Research Center

US Patent
LigandChemical structure of BindingDB Monomer ID 50069104BDBM50069104(CHEMBL1449583 | US9182402, 4)
Affinity DataIC50: 2.00E+4nMAssay Description:To identify novel inhibitors of hepsin, the Chembridge DIVERSet 10,000 compound high-diversity library was screened using an assay based on the cleav...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/6/2016
Entry Details
US Patent

TargetProthrombin(Bovine)
Fred Hutchinson Cancer Research Center

US Patent
LigandChemical structure of BindingDB Monomer ID 191634BDBM191634(US9182402, 7)
Affinity DataIC50: 2.00E+4nMAssay Description:To identify novel inhibitors of hepsin, the Chembridge DIVERSet 10,000 compound high-diversity library was screened using an assay based on the cleav...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/6/2016
Entry Details
US Patent

TargetProthrombin(Bovine)
Fred Hutchinson Cancer Research Center

US Patent
LigandChemical structure of BindingDB Monomer ID 191633BDBM191633(US9182402, 6)
Affinity DataIC50: 2.00E+4nMAssay Description:To identify novel inhibitors of hepsin, the Chembridge DIVERSet 10,000 compound high-diversity library was screened using an assay based on the cleav...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/6/2016
Entry Details
US Patent

TargetProthrombin(Bovine)
Fred Hutchinson Cancer Research Center

US Patent
LigandChemical structure of BindingDB Monomer ID 50013876BDBM50013876(N-Methyl-D-aspartate | N-Methyl aspartic acid | CH...)
Affinity DataIC50: 2.00E+4nMAssay Description:To identify novel inhibitors of hepsin, the Chembridge DIVERSet 10,000 compound high-diversity library was screened using an assay based on the cleav...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/6/2016
Entry Details
US Patent

TargetTrypsin(Pig)
Fred Hutchinson Cancer Research Center

US Patent
LigandChemical structure of BindingDB Monomer ID 191632BDBM191632(US9182402, 2)
Affinity DataIC50: 2.00E+4nMAssay Description:To identify novel inhibitors of hepsin, the Chembridge DIVERSet 10,000 compound high-diversity library was screened using an assay based on the cleav...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/6/2016
Entry Details
US Patent

TargetProthrombin(Bovine)
Fred Hutchinson Cancer Research Center

US Patent
LigandChemical structure of BindingDB Monomer ID 81467BDBM81467(CHEMBL1085765 | NSC_4034 | CAS_569-65-3 | Meclizin...)
Affinity DataIC50: 2.00E+4nMAssay Description:To identify novel inhibitors of hepsin, the Chembridge DIVERSet 10,000 compound high-diversity library was screened using an assay based on the cleav...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/6/2016
Entry Details
US Patent

TargetProthrombin(Bovine)
Fred Hutchinson Cancer Research Center

US Patent
LigandChemical structure of BindingDB Monomer ID 191639BDBM191639(US9182402, 12)
Affinity DataIC50: 2.00E+4nMAssay Description:To identify novel inhibitors of hepsin, the Chembridge DIVERSet 10,000 compound high-diversity library was screened using an assay based on the cleav...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/6/2016
Entry Details
US Patent

TargetProthrombin(Bovine)
Fred Hutchinson Cancer Research Center

US Patent
LigandChemical structure of BindingDB Monomer ID 50041802BDBM50041802(CHEMBL46469 | 1,8-dihydroxyanthrone | 1,8-dihydrox...)
Affinity DataIC50: 2.00E+4nMAssay Description:To identify novel inhibitors of hepsin, the Chembridge DIVERSet 10,000 compound high-diversity library was screened using an assay based on the cleav...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/6/2016
Entry Details
US Patent

TargetProthrombin(Bovine)
Fred Hutchinson Cancer Research Center

US Patent
LigandChemical structure of BindingDB Monomer ID 50007260BDBM50007260(2,6-di-tert-butyl-4-(2-(3,5-di-tert-butyl-4-hydrox...)
Affinity DataIC50: 2.00E+4nMAssay Description:To identify novel inhibitors of hepsin, the Chembridge DIVERSet 10,000 compound high-diversity library was screened using an assay based on the cleav...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/6/2016
Entry Details
US Patent

TargetProthrombin(Bovine)
Fred Hutchinson Cancer Research Center

US Patent
LigandChemical structure of BindingDB Monomer ID 191630BDBM191630(US9182402, 3)
Affinity DataIC50: 2.00E+4nMAssay Description:To identify novel inhibitors of hepsin, the Chembridge DIVERSet 10,000 compound high-diversity library was screened using an assay based on the cleav...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/6/2016
Entry Details
US Patent

TargetProthrombin(Bovine)
Fred Hutchinson Cancer Research Center

US Patent
LigandChemical structure of BindingDB Monomer ID 191632BDBM191632(US9182402, 2)
Affinity DataIC50: 2.00E+4nMAssay Description:To identify novel inhibitors of hepsin, the Chembridge DIVERSet 10,000 compound high-diversity library was screened using an assay based on the cleav...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/6/2016
Entry Details
US Patent

TargetTrypsin(Pig)
Fred Hutchinson Cancer Research Center

US Patent
LigandChemical structure of BindingDB Monomer ID 81467BDBM81467(CHEMBL1085765 | NSC_4034 | CAS_569-65-3 | Meclizin...)
Affinity DataIC50: 2.00E+4nMAssay Description:To identify novel inhibitors of hepsin, the Chembridge DIVERSet 10,000 compound high-diversity library was screened using an assay based on the cleav...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/6/2016
Entry Details
US Patent

TargetTrypsin(Pig)
Fred Hutchinson Cancer Research Center

US Patent
LigandChemical structure of BindingDB Monomer ID 191636BDBM191636(US9182402, 9)
Affinity DataIC50: 2.09E+4nMAssay Description:To identify novel inhibitors of hepsin, the Chembridge DIVERSet 10,000 compound high-diversity library was screened using an assay based on the cleav...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/6/2016
Entry Details
US Patent

TargetTrypsin(Pig)
Fred Hutchinson Cancer Research Center

US Patent
LigandChemical structure of BindingDB Monomer ID 191631BDBM191631(US9182402, 5)
Affinity DataIC50: 3.12E+4nMAssay Description:To identify novel inhibitors of hepsin, the Chembridge DIVERSet 10,000 compound high-diversity library was screened using an assay based on the cleav...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/6/2016
Entry Details
US Patent

TargetTrypsin(Pig)
Fred Hutchinson Cancer Research Center

US Patent
LigandChemical structure of BindingDB Monomer ID 50007260BDBM50007260(2,6-di-tert-butyl-4-(2-(3,5-di-tert-butyl-4-hydrox...)
Affinity DataIC50: 3.35E+4nMAssay Description:To identify novel inhibitors of hepsin, the Chembridge DIVERSet 10,000 compound high-diversity library was screened using an assay based on the cleav...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/6/2016
Entry Details
US Patent