Compile Data Set for Download or QSAR
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Report error Found 23 Enz. Inhib. hit(s) with all data for entry = 7369
TargetTranscription factor Jun(Human)
Stc.Unm

US Patent
LigandPNGBDBM191748(US9187397, 20m)
Affinity DataIC50:  1.40E+3nMAssay Description:The 293T/NF-κB-luc cells were re-plated 24 hr prior to treatment, into 24-well cell culture plates in media without hygromycin, to prevent it from...More data for this Ligand-Target Pair
In DepthDetails US Patent


TargetNuclear factor NF-kappa-B p105 subunit(Human)
Stc.Unm

US Patent
LigandPNGBDBM191744(US9187397, 3 | US9187397, 31)
Affinity DataIC50:  3.40E+3nMAssay Description:The 293T/NF-κB-luc cells were re-plated 24 hr prior to treatment, into 24-well cell culture plates in media without hygromycin, to prevent it from...More data for this Ligand-Target Pair
In DepthDetails US Patent


TargetNuclear factor NF-kappa-B p105 subunit(Human)
Stc.Unm

US Patent
LigandPNGBDBM191744(US9187397, 3 | US9187397, 31)
Affinity DataIC50:  3.40E+3nMAssay Description:The 293T/NF-κB-luc cells were re-plated 24 hr prior to treatment, into 24-well cell culture plates in media without hygromycin, to prevent it from...More data for this Ligand-Target Pair
In DepthDetails US Patent


TargetNuclear factor NF-kappa-B p105 subunit(Human)
Stc.Unm

US Patent
LigandPNGBDBM191745(US9187397, 29)
Affinity DataIC50:  3.50E+3nMAssay Description:The 293T/NF-κB-luc cells were re-plated 24 hr prior to treatment, into 24-well cell culture plates in media without hygromycin, to prevent it from...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetTranscription factor Jun(Human)
Stc.Unm

US Patent
LigandPNGBDBM191744(US9187397, 3 | US9187397, 31)
Affinity DataIC50:  4.10E+3nMAssay Description:The 293T/NF-κB-luc cells were re-plated 24 hr prior to treatment, into 24-well cell culture plates in media without hygromycin, to prevent it from...More data for this Ligand-Target Pair
In DepthDetails US Patent


TargetNuclear factor NF-kappa-B p105 subunit(Human)
Stc.Unm

US Patent
LigandPNGBDBM50067033((2E,6E)-2,6-bis(4-hydroxy-3-methoxybenzylidene)cyc...)
Affinity DataIC50:  4.20E+3nMAssay Description:TRAP Assay: The first procedure called for antioxidant activity to be measured as the ability of the analogs to react with the pre-formed radical mon...More data for this Ligand-Target Pair
In DepthDetails US Patent


TargetNuclear factor NF-kappa-B p105 subunit(Human)
Stc.Unm

US Patent
LigandPNGBDBM191746(US9187397, 20q)
Affinity DataIC50:  4.20E+3nMAssay Description:The first procedure called for antioxidant activity to be measured as the ability of the analogs to react with the pre-formed radical monocation of 2...More data for this Ligand-Target Pair
In DepthDetails US Patent


TargetNuclear factor NF-kappa-B p105 subunit(Human)
Stc.Unm

US Patent
LigandPNGBDBM50067033((2E,6E)-2,6-bis(4-hydroxy-3-methoxybenzylidene)cyc...)
Affinity DataIC50:  4.40E+3nMAssay Description:The 293T/NF-κB-luc cells were re-plated 24 hr prior to treatment, into 24-well cell culture plates in media without hygromycin, to prevent it from...More data for this Ligand-Target Pair
In DepthDetails US Patent


TargetNuclear factor NF-kappa-B p105 subunit(Human)
Stc.Unm

US Patent
LigandPNGBDBM191762(US9187397, 5)
Affinity DataIC50:  5.00E+3nMAssay Description:The 293T/NF-κB-luc cells were re-plated 24 hr prior to treatment, into 24-well cell culture plates in media without hygromycin, to prevent it from...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetTranscription factor Jun(Human)
Stc.Unm

US Patent
LigandPNGBDBM191750(US9187397, 9a)
Affinity DataIC50:  5.30E+3nMAssay Description:TRAP Assay: The first procedure called for antioxidant activity to be measured as the ability of the analogs to react with the pre-formed radical mon...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetNuclear factor NF-kappa-B p105 subunit(Human)
Stc.Unm

US Patent
LigandPNGBDBM191747(US9187397, 20ag)
Affinity DataIC50:  5.40E+3nMAssay Description:Anti-oxidant activity was also measured in the Ferric reducing/anti-oxidant power assay (FRAP assay) in which the analogs are reacted with a ferric t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetTranscription factor Jun(Human)
Stc.Unm

US Patent
LigandPNGBDBM191749(US9187397, 2 | US9187397, 6a)
Affinity DataIC50:  6.00E+3nMAssay Description:TRAP Assay: The first procedure called for antioxidant activity to be measured as the ability of the analogs to react with the pre-formed radical mon...More data for this Ligand-Target Pair
In DepthDetails US Patent


TargetNuclear factor NF-kappa-B p105 subunit(Human)
Stc.Unm

US Patent
LigandPNGBDBM191748(US9187397, 20m)
Affinity DataIC50:  6.40E+3nMAssay Description:The 293T/NF-κB-luc cells were re-plated 24 hr prior to treatment, into 24-well cell culture plates in media without hygromycin, to prevent it from...More data for this Ligand-Target Pair
In DepthDetails US Patent


TargetNuclear factor NF-kappa-B p105 subunit(Human)
Stc.Unm

US Patent
LigandPNGBDBM191749(US9187397, 2 | US9187397, 6a)
Affinity DataIC50:  6.70E+3nMAssay Description:TRAP Assay: The first procedure called for antioxidant activity to be measured as the ability of the analogs to react with the pre-formed radical mon...More data for this Ligand-Target Pair
In DepthDetails US Patent


TargetNuclear factor NF-kappa-B p105 subunit(Human)
Stc.Unm

US Patent
LigandPNGBDBM191749(US9187397, 2 | US9187397, 6a)
Affinity DataIC50:  6.70E+3nMAssay Description:The 293T/NF-κB-luc cells were re-plated 24 hr prior to treatment, into 24-well cell culture plates in media without hygromycin, to prevent it from...More data for this Ligand-Target Pair
In DepthDetails US Patent


TargetTranscription factor Jun(Human)
Stc.Unm

US Patent
LigandPNGBDBM50067033((2E,6E)-2,6-bis(4-hydroxy-3-methoxybenzylidene)cyc...)
Affinity DataIC50:  7.30E+3nMAssay Description:TRAP Assay: The first procedure called for antioxidant activity to be measured as the ability of the analogs to react with the pre-formed radical mon...More data for this Ligand-Target Pair
In DepthDetails US Patent


TargetNuclear factor NF-kappa-B p105 subunit(Human)
Stc.Unm

US Patent
LigandPNGBDBM191750(US9187397, 9a)
Affinity DataIC50:  7.60E+3nMAssay Description:TRAP Assay: The first procedure called for antioxidant activity to be measured as the ability of the analogs to react with the pre-formed radical mon...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetTranscription factor Jun(Human)
Stc.Unm

US Patent
LigandPNGBDBM191745(US9187397, 29)
Affinity DataIC50:  8.20E+3nMAssay Description:The 293T/NF-κB-luc cells were re-plated 24 hr prior to treatment, into 24-well cell culture plates in media without hygromycin, to prevent it from...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetNuclear factor NF-kappa-B p105 subunit(Human)
Stc.Unm

US Patent
LigandPNGBDBM191758(US9187397, 1 (curcumin) | US9187397, 3a)
Affinity DataIC50:  8.20E+3nMAssay Description:TRAP Assay: The first procedure called for antioxidant activity to be measured as the ability of the analogs to react with the pre-formed radical mon...More data for this Ligand-Target Pair
In DepthDetails US Patent


TargetNuclear factor NF-kappa-B p105 subunit(Human)
Stc.Unm

US Patent
LigandPNGBDBM191763(US10669227, Compound Curcumin | US11608309, Compou...)
Affinity DataIC50:  8.20E+3nMAssay Description:The 293T/NF-κB-luc cells were re-plated 24 hr prior to treatment, into 24-well cell culture plates in media without hygromycin, to prevent it from...More data for this Ligand-Target Pair
In DepthDetails US Patent


TargetTranscription factor Jun(Human)
Stc.Unm

US Patent
LigandPNGBDBM191747(US9187397, 20ag)
Affinity DataIC50:  8.30E+3nMAssay Description:Anti-oxidant activity was also measured in the Ferric reducing/anti-oxidant power assay (FRAP assay) in which the analogs are reacted with a ferric t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetTranscription factor Jun(Human)
Stc.Unm

US Patent
LigandPNGBDBM191746(US9187397, 20q)
Affinity DataIC50:  1.17E+4nMAssay Description:The first procedure called for antioxidant activity to be measured as the ability of the analogs to react with the pre-formed radical monocation of 2...More data for this Ligand-Target Pair
In DepthDetails US Patent


TargetTranscription factor Jun(Human)
Stc.Unm

US Patent
LigandPNGBDBM191758(US9187397, 1 (curcumin) | US9187397, 3a)
Affinity DataIC50:  1.28E+4nMAssay Description:The 293T/NF-κB-luc cells were re-plated 24 hr prior to treatment, into 24-well cell culture plates in media without hygromycin, to prevent it from...More data for this Ligand-Target Pair
In DepthDetails US Patent