Compile Data Set for Download or QSAR
Report error Found 203 Enz. Inhib. hit(s) with all data for entry = 7455
TargetGenome polyprotein(HCV)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 196124BDBM196124(US9206232, 125)
Affinity DataIC50: 0.300nMAssay Description:The inhibitory activity of certain compounds of Table A against HCV NS3-4A serine protease is determined in a homogenous assay using the full-length ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2016
Entry Details
US Patent

TargetGenome polyprotein(HCV)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 110396BDBM110396(US8613914, 170 | US9206232, 170)
Affinity DataIC50: 0.5nMAssay Description:The inhibitory activity of certain compounds of Table A against HCV NS3-4A serine protease is determined in a homogenous assay using the full-length ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2016
Entry Details
US Patent

TargetGenome polyprotein(HCV)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 110393BDBM110393(US8613914, 167 | US9206232, 167)
Affinity DataIC50: 0.600nMAssay Description:The inhibitory activity of certain compounds of Table A against HCV NS3-4A serine protease is determined in a homogenous assay using the full-length ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2016
Entry Details
US Patent

TargetGenome polyprotein(HCV)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 110400BDBM110400(US8613914, 174 | US9206232, 174)
Affinity DataIC50: 0.600nMAssay Description:The inhibitory activity of certain compounds of Table A against HCV NS3-4A serine protease is determined in a homogenous assay using the full-length ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2016
Entry Details
US Patent

TargetGenome polyprotein(HCV)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 110388BDBM110388(US8613914, 162 | US9206232, 162)
Affinity DataIC50: 0.800nMAssay Description:The inhibitory activity of certain compounds of Table A against HCV NS3-4A serine protease is determined in a homogenous assay using the full-length ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2016
Entry Details
US Patent

TargetGenome polyprotein(HCV)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 110273BDBM110273(US8613914, 41 | US9206232, 41)
Affinity DataIC50: 0.900nMAssay Description:The inhibitory activity of certain compounds of Table A against HCV NS3-4A serine protease is determined in a homogenous assay using the full-length ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2016
Entry Details
US Patent

TargetGenome polyprotein(HCV)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 110280BDBM110280(US8613914, 48 | US9206232, 48)
Affinity DataIC50: 0.900nMAssay Description:The inhibitory activity of certain compounds of Table A against HCV NS3-4A serine protease is determined in a homogenous assay using the full-length ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2016
Entry Details
US Patent

TargetGenome polyprotein(HCV)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 110388BDBM110388(US8613914, 162 | US9206232, 162)
Affinity DataIC50: 0.900nMAssay Description:The inhibitory activity of certain compounds of Table A against HCV NS3-4A serine protease is determined in a homogenous assay using the full-length ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2016
Entry Details
US Patent

TargetGenome polyprotein(HCV)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 196120BDBM196120(US9206232, 77)
Affinity DataIC50: 0.900nMAssay Description:The inhibitory activity of certain compounds of Table A against HCV NS3-4A serine protease is determined in a homogenous assay using the full-length ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2016
Entry Details
US Patent

TargetGenome polyprotein(HCV)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 110397BDBM110397(US8613914, 171 | US9206232, 171)
Affinity DataIC50: 1nMAssay Description:The inhibitory activity of certain compounds of Table A against HCV NS3-4A serine protease is determined in a homogenous assay using the full-length ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2016
Entry Details
US Patent

TargetGenome polyprotein(HCV)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 110264BDBM110264(US8613914, 32 | US9206232, 32)
Affinity DataIC50: 1nMAssay Description:The inhibitory activity of certain compounds of Table A against HCV NS3-4A serine protease is determined in a homogenous assay using the full-length ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2016
Entry Details
US Patent

TargetGenome polyprotein(HCV)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 110277BDBM110277(US8613914, 45 | US9206232, 45)
Affinity DataIC50: 1nMAssay Description:The inhibitory activity of certain compounds of Table A against HCV NS3-4A serine protease is determined in a homogenous assay using the full-length ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2016
Entry Details
US Patent

TargetGenome polyprotein(HCV)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 110383BDBM110383(US8613914, 157 | US9206232, 157)
Affinity DataIC50: 1nMAssay Description:The inhibitory activity of certain compounds of Table A against HCV NS3-4A serine protease is determined in a homogenous assay using the full-length ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2016
Entry Details
US Patent

TargetGenome polyprotein(HCV)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 110294BDBM110294(US8613914, 62 | US9206232, 62)
Affinity DataIC50: 1nMAssay Description:The inhibitory activity of certain compounds of Table A against HCV NS3-4A serine protease is determined in a homogenous assay using the full-length ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2016
Entry Details
US Patent

TargetGenome polyprotein(HCV)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 110378BDBM110378(US8613914, 152 | US9206232, 152)
Affinity DataIC50: 1.10nMAssay Description:The inhibitory activity of certain compounds of Table A against HCV NS3-4A serine protease is determined in a homogenous assay using the full-length ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2016
Entry Details
US Patent

TargetGenome polyprotein(HCV)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 110295BDBM110295(US8613914, 63 | US9206232, 63)
Affinity DataIC50: 1.20nMAssay Description:The inhibitory activity of certain compounds of Table A against HCV NS3-4A serine protease is determined in a homogenous assay using the full-length ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2016
Entry Details
US Patent

TargetGenome polyprotein(HCV)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 110382BDBM110382(US8613914, 156 | US9206232, 156)
Affinity DataIC50: 1.30nMAssay Description:The inhibitory activity of certain compounds of Table A against HCV NS3-4A serine protease is determined in a homogenous assay using the full-length ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2016
Entry Details
US Patent

TargetGenome polyprotein(HCV)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 110354BDBM110354(US8613914, 122 | US9206232, 122)
Affinity DataIC50: 1.40nMAssay Description:The inhibitory activity of certain compounds of Table A against HCV NS3-4A serine protease is determined in a homogenous assay using the full-length ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2016
Entry Details
US Patent

TargetGenome polyprotein(HCV)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 110287BDBM110287(US8613914, 55 | US9206232, 55)
Affinity DataIC50: 1.40nMAssay Description:The inhibitory activity of certain compounds of Table A against HCV NS3-4A serine protease is determined in a homogenous assay using the full-length ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2016
Entry Details
US Patent

TargetGenome polyprotein(HCV)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 110344BDBM110344(US8613914, 112 | US9206232, 112)
Affinity DataIC50: 1.40nMAssay Description:The inhibitory activity of certain compounds of Table A against HCV NS3-4A serine protease is determined in a homogenous assay using the full-length ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2016
Entry Details
US Patent

TargetGenome polyprotein(HCV)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 110360BDBM110360(US8613914, 128 | US9206232, 128)
Affinity DataIC50: 1.40nMAssay Description:The inhibitory activity of certain compounds of Table A against HCV NS3-4A serine protease is determined in a homogenous assay using the full-length ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2016
Entry Details
US Patent

TargetGenome polyprotein(HCV)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 110395BDBM110395(US8613914, 169 | US9206232, 169)
Affinity DataIC50: 1.5nMAssay Description:The inhibitory activity of certain compounds of Table A against HCV NS3-4A serine protease is determined in a homogenous assay using the full-length ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2016
Entry Details
US Patent

TargetGenome polyprotein(HCV)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 196129BDBM196129(US9206232, 149)
Affinity DataIC50: 1.5nMAssay Description:The inhibitory activity of certain compounds of Table A against HCV NS3-4A serine protease is determined in a homogenous assay using the full-length ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2016
Entry Details
US Patent

TargetGenome polyprotein(HCV)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 110375BDBM110375(US8613914, 147 | US9206232, 147)
Affinity DataIC50: 1.5nMAssay Description:The inhibitory activity of certain compounds of Table A against HCV NS3-4A serine protease is determined in a homogenous assay using the full-length ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2016
Entry Details
US Patent

TargetGenome polyprotein(HCV)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 110356BDBM110356(US8613914, 124 | US9206232, 124)
Affinity DataIC50: 1.5nMAssay Description:The inhibitory activity of certain compounds of Table A against HCV NS3-4A serine protease is determined in a homogenous assay using the full-length ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2016
Entry Details
US Patent

TargetGenome polyprotein(HCV)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 110326BDBM110326(US8613914, 94 | US9206232, 94)
Affinity DataIC50: 1.5nMAssay Description:The inhibitory activity of certain compounds of Table A against HCV NS3-4A serine protease is determined in a homogenous assay using the full-length ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2016
Entry Details
US Patent

TargetGenome polyprotein(HCV)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 110285BDBM110285(US8613914, 53 | US9206232, 53)
Affinity DataIC50: 1.70nMAssay Description:The inhibitory activity of certain compounds of Table A against HCV NS3-4A serine protease is determined in a homogenous assay using the full-length ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2016
Entry Details
US Patent

TargetGenome polyprotein(HCV)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 110379BDBM110379(US8613914, 153 | US9206232, 153)
Affinity DataIC50: 1.80nMAssay Description:The inhibitory activity of certain compounds of Table A against HCV NS3-4A serine protease is determined in a homogenous assay using the full-length ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2016
Entry Details
US Patent

TargetGenome polyprotein(HCV)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 110377BDBM110377(US8613914, 151 | US9206232, 151)
Affinity DataIC50: 2nMAssay Description:The inhibitory activity of certain compounds of Table A against HCV NS3-4A serine protease is determined in a homogenous assay using the full-length ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2016
Entry Details
US Patent

TargetGenome polyprotein(HCV)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 110296BDBM110296(US8613914, 64 | US9206232, 64)
Affinity DataIC50: 2nMAssay Description:The inhibitory activity of certain compounds of Table A against HCV NS3-4A serine protease is determined in a homogenous assay using the full-length ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2016
Entry Details
US Patent

TargetGenome polyprotein(HCV)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 196122BDBM196122(US9206232, 80)
Affinity DataIC50: 2nMAssay Description:The inhibitory activity of certain compounds of Table A against HCV NS3-4A serine protease is determined in a homogenous assay using the full-length ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2016
Entry Details
US Patent

TargetGenome polyprotein(HCV)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 110315BDBM110315(US8613914, 83 | US9206232, 83)
Affinity DataIC50: 2nMAssay Description:The inhibitory activity of certain compounds of Table A against HCV NS3-4A serine protease is determined in a homogenous assay using the full-length ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2016
Entry Details
US Patent

TargetGenome polyprotein(HCV)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 110325BDBM110325(US8613914, 93 | US9206232, 93)
Affinity DataIC50: 2nMAssay Description:The inhibitory activity of certain compounds of Table A against HCV NS3-4A serine protease is determined in a homogenous assay using the full-length ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2016
Entry Details
US Patent

TargetGenome polyprotein(HCV)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 110260BDBM110260(US8613914, 28 | US9206232, 28)
Affinity DataIC50: 2nMAssay Description:The inhibitory activity of certain compounds of Table A against HCV NS3-4A serine protease is determined in a homogenous assay using the full-length ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2016
Entry Details
US Patent

TargetGenome polyprotein(HCV)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 110247BDBM110247(US8613914, 15 | US9206232, 15)
Affinity DataIC50: 2nMAssay Description:The inhibitory activity of certain compounds of Table A against HCV NS3-4A serine protease is determined in a homogenous assay using the full-length ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2016
Entry Details
US Patent

TargetGenome polyprotein(HCV)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 110278BDBM110278(US8613914, 46 | US9206232, 46)
Affinity DataIC50: 2nMAssay Description:The inhibitory activity of certain compounds of Table A against HCV NS3-4A serine protease is determined in a homogenous assay using the full-length ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2016
Entry Details
US Patent

TargetGenome polyprotein(HCV)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 110248BDBM110248(US8613914, 16 | US9206232, 16)
Affinity DataIC50: 2.30nMAssay Description:The inhibitory activity of certain compounds of Table A against HCV NS3-4A serine protease is determined in a homogenous assay using the full-length ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2016
Entry Details
US Patent

TargetGenome polyprotein(HCV)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 110376BDBM110376(US8613914, 150 | US9206232, 150)
Affinity DataIC50: 2.40nMAssay Description:The inhibitory activity of certain compounds of Table A against HCV NS3-4A serine protease is determined in a homogenous assay using the full-length ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2016
Entry Details
US Patent

TargetGenome polyprotein(HCV)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 110333BDBM110333(US8613914, 101 | US9206232, 101)
Affinity DataIC50: 2.5nMAssay Description:The inhibitory activity of certain compounds of Table A against HCV NS3-4A serine protease is determined in a homogenous assay using the full-length ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2016
Entry Details
US Patent

TargetGenome polyprotein(HCV)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 110284BDBM110284(US8613914, 52 | US9206232, 52)
Affinity DataIC50: 2.5nMAssay Description:The inhibitory activity of certain compounds of Table A against HCV NS3-4A serine protease is determined in a homogenous assay using the full-length ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2016
Entry Details
US Patent

TargetGenome polyprotein(HCV)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 110271BDBM110271(US8613914, 39 | US9206232, 39)
Affinity DataIC50: 2.5nMAssay Description:The inhibitory activity of certain compounds of Table A against HCV NS3-4A serine protease is determined in a homogenous assay using the full-length ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2016
Entry Details
US Patent

TargetGenome polyprotein(HCV)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 110286BDBM110286(US8613914, 54 | US9206232, 54)
Affinity DataIC50: 2.5nMAssay Description:The inhibitory activity of certain compounds of Table A against HCV NS3-4A serine protease is determined in a homogenous assay using the full-length ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2016
Entry Details
US Patent

TargetGenome polyprotein(HCV)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 110249BDBM110249(US8613914, 17 | US9206232, 17)
Affinity DataIC50: 2.5nMAssay Description:The inhibitory activity of certain compounds of Table A against HCV NS3-4A serine protease is determined in a homogenous assay using the full-length ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2016
Entry Details
US Patent

TargetGenome polyprotein(HCV)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 110314BDBM110314(US8613914, 82 | US9206232, 82)
Affinity DataIC50: 2.5nMAssay Description:The inhibitory activity of certain compounds of Table A against HCV NS3-4A serine protease is determined in a homogenous assay using the full-length ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2016
Entry Details
US Patent

TargetGenome polyprotein(HCV)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 110341BDBM110341(US8613914, 109 | US9206232, 109)
Affinity DataIC50: 2.5nMAssay Description:The inhibitory activity of certain compounds of Table A against HCV NS3-4A serine protease is determined in a homogenous assay using the full-length ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2016
Entry Details
US Patent

TargetGenome polyprotein(HCV)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 196128BDBM196128(US9206232, 140)
Affinity DataIC50: 2.5nMAssay Description:The inhibitory activity of certain compounds of Table A against HCV NS3-4A serine protease is determined in a homogenous assay using the full-length ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2016
Entry Details
US Patent

TargetGenome polyprotein(HCV)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 110398BDBM110398(US8613914, 172 | US9206232, 172)
Affinity DataIC50: 2.5nMAssay Description:The inhibitory activity of certain compounds of Table A against HCV NS3-4A serine protease is determined in a homogenous assay using the full-length ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2016
Entry Details
US Patent

TargetGenome polyprotein(HCV)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 196121BDBM196121(US9206232, 79)
Affinity DataIC50: 2.5nMAssay Description:The inhibitory activity of certain compounds of Table A against HCV NS3-4A serine protease is determined in a homogenous assay using the full-length ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2016
Entry Details
US Patent

TargetGenome polyprotein(HCV)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 110380BDBM110380(US8613914, 154 | US9206232, 154)
Affinity DataIC50: 2.80nMAssay Description:The inhibitory activity of certain compounds of Table A against HCV NS3-4A serine protease is determined in a homogenous assay using the full-length ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2016
Entry Details
US Patent

TargetGenome polyprotein(HCV)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 110364BDBM110364(US8613914, 132 | US9206232, 132)
Affinity DataIC50: 2.80nMAssay Description:The inhibitory activity of certain compounds of Table A against HCV NS3-4A serine protease is determined in a homogenous assay using the full-length ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2016
Entry Details
US Patent

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