Compile Data Set for Download or QSAR
maximum 50k data
Found 10 Enz. Inhib. hit(s) with all data for entry = 7510
TargetIsoform 1 of Metabotropic glutamate receptor 5 (5a)(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM198909(US9221802, Ref. Ex. 20 | US9315498, 20)
Affinity DataEC50:  27nMT: 2°CAssay Description:About 24 hrs before an experiment, 5x104 cells/well were seeded in poly-D-lysine coated, black/clear-bottomed 96-well plates. The cells were loaded...More data for this Ligand-Target Pair
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In DepthDetails US Patent
TargetIsoform 1 of Metabotropic glutamate receptor 5 (5a)(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM198910(US9221802, Ref. Ex. 72 | US9315498, 72)
Affinity DataEC50:  10nMT: 2°CAssay Description:About 24 hrs before an experiment, 5x104 cells/well were seeded in poly-D-lysine coated, black/clear-bottomed 96-well plates. The cells were loaded...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetIsoform 1 of Metabotropic glutamate receptor 5 (5a)(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM198911(US9221802, Ref. Ex. 76 | US9315498, 76)
Affinity DataEC50:  13nMT: 2°CAssay Description:About 24 hrs before an experiment, 5x104 cells/well were seeded in poly-D-lysine coated, black/clear-bottomed 96-well plates. The cells were loaded...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetIsoform 1 of Metabotropic glutamate receptor 5 (5a)(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM198912(US9221802, Ref. Ex. 79 | US9315498, 79)
Affinity DataEC50:  22nMT: 2°CAssay Description:About 24 hrs before an experiment, 5x104 cells/well were seeded in poly-D-lysine coated, black/clear-bottomed 96-well plates. The cells were loaded...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetIsoform 1 of Metabotropic glutamate receptor 5 (5a)(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM198918(US9221802, Ex. 4)
Affinity DataEC50:  15nMT: 2°CAssay Description:About 24 hrs before an experiment, 5x104 cells/well were seeded in poly-D-lysine coated, black/clear-bottomed 96-well plates. The cells were loaded...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetIsoform 1 of Metabotropic glutamate receptor 5 (5a)(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM198914(US9221802, Ref. Ex. 103 | US9315498, 103)
Affinity DataEC50:  27nMT: 2°CAssay Description:About 24 hrs before an experiment, 5x104 cells/well were seeded in poly-D-lysine coated, black/clear-bottomed 96-well plates. The cells were loaded...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetIsoform 1 of Metabotropic glutamate receptor 5 (5a)(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM198915(US9221802, Ex. 1)
Affinity DataEC50:  22nMT: 2°CAssay Description:About 24 hrs before an experiment, 5x104 cells/well were seeded in poly-D-lysine coated, black/clear-bottomed 96-well plates. The cells were loaded...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetIsoform 1 of Metabotropic glutamate receptor 5 (5a)(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM198916(US9221802, Ex. 2)
Affinity DataEC50:  10nMT: 2°CAssay Description:About 24 hrs before an experiment, 5x104 cells/well were seeded in poly-D-lysine coated, black/clear-bottomed 96-well plates. The cells were loaded...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetIsoform 1 of Metabotropic glutamate receptor 5 (5a)(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM198917(US9221802, Ex. 3)
Affinity DataEC50:  10nMT: 2°CAssay Description:About 24 hrs before an experiment, 5x104 cells/well were seeded in poly-D-lysine coated, black/clear-bottomed 96-well plates. The cells were loaded...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetIsoform 1 of Metabotropic glutamate receptor 5 (5a)(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM198913(US9221802, Ref. Ex. 81 | US9315498, 81)
Affinity DataEC50:  12nMT: 2°CAssay Description:About 24 hrs before an experiment, 5x104 cells/well were seeded in poly-D-lysine coated, black/clear-bottomed 96-well plates. The cells were loaded...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent