Compile Data Set for Download or QSAR
Report error Found 33 Enz. Inhib. hit(s) with all data for entry = 7553
TargetBeta-secretase 1(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 202064BDBM202064(US9233981, 26)
Affinity DataIC50: 6nMpH: 4.5 T: 2°CAssay Description:A synthetic APP substrate that can be cleaved by beta-secretase having N-terminal biotin and made fluorescent by the covalent attachment of Oregon Gr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2016
Entry Details
US Patent

TargetBeta-secretase 1(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 202047BDBM202047(US9233981, 8)
Affinity DataIC50: 6nMpH: 4.5 T: 2°CAssay Description:A synthetic APP substrate that can be cleaved by beta-secretase having N-terminal biotin and made fluorescent by the covalent attachment of Oregon Gr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2016
Entry Details
US Patent

TargetBeta-secretase 1(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 202044BDBM202044(US9233981, 5)
Affinity DataIC50: 10nMpH: 4.5 T: 2°CAssay Description:A synthetic APP substrate that can be cleaved by beta-secretase having N-terminal biotin and made fluorescent by the covalent attachment of Oregon Gr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2016
Entry Details
US Patent

TargetBeta-secretase 1(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 202071BDBM202071(US9233981, 33)
Affinity DataIC50: 11nMpH: 4.5 T: 2°CAssay Description:A synthetic APP substrate that can be cleaved by beta-secretase having N-terminal biotin and made fluorescent by the covalent attachment of Oregon Gr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2016
Entry Details
US Patent

TargetBeta-secretase 1(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 202061BDBM202061(US9233981, 23)
Affinity DataIC50: 11nMpH: 4.5 T: 2°CAssay Description:A synthetic APP substrate that can be cleaved by beta-secretase having N-terminal biotin and made fluorescent by the covalent attachment of Oregon Gr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2016
Entry Details
US Patent

TargetBeta-secretase 1(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 202048BDBM202048(US9233981, 9)
Affinity DataIC50: 13nMpH: 4.5 T: 2°CAssay Description:A synthetic APP substrate that can be cleaved by beta-secretase having N-terminal biotin and made fluorescent by the covalent attachment of Oregon Gr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2016
Entry Details
US Patent

TargetBeta-secretase 1(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 202072BDBM202072(US9233981, 34)
Affinity DataIC50: 14nMpH: 4.5 T: 2°CAssay Description:A synthetic APP substrate that can be cleaved by beta-secretase having N-terminal biotin and made fluorescent by the covalent attachment of Oregon Gr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2016
Entry Details
US Patent

TargetBeta-secretase 1(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 202040BDBM202040(US9233981, 1)
Affinity DataIC50: 14nMpH: 4.5 T: 2°CAssay Description:A synthetic APP substrate that can be cleaved by beta-secretase having N-terminal biotin and made fluorescent by the covalent attachment of Oregon Gr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2016
Entry Details
US Patent

TargetBeta-secretase 1(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 202070BDBM202070(US9233981, 32)
Affinity DataIC50: 15nMpH: 4.5 T: 2°CAssay Description:A synthetic APP substrate that can be cleaved by beta-secretase having N-terminal biotin and made fluorescent by the covalent attachment of Oregon Gr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2016
Entry Details
US Patent

TargetBeta-secretase 1(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 202051BDBM202051(US9233981, 12)
Affinity DataIC50: 15nMpH: 4.5 T: 2°CAssay Description:A synthetic APP substrate that can be cleaved by beta-secretase having N-terminal biotin and made fluorescent by the covalent attachment of Oregon Gr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2016
Entry Details
US Patent

TargetBeta-secretase 1(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 202049BDBM202049(US9233981, 10)
Affinity DataIC50: 16nMpH: 4.5 T: 2°CAssay Description:A synthetic APP substrate that can be cleaved by beta-secretase having N-terminal biotin and made fluorescent by the covalent attachment of Oregon Gr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2016
Entry Details
US Patent

TargetBeta-secretase 1(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 202065BDBM202065(US9233981, 27)
Affinity DataIC50: 19nMpH: 4.5 T: 2°CAssay Description:A synthetic APP substrate that can be cleaved by beta-secretase having N-terminal biotin and made fluorescent by the covalent attachment of Oregon Gr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2016
Entry Details
US Patent

TargetBeta-secretase 1(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 202053BDBM202053(US9233981, 15)
Affinity DataIC50: 21nMpH: 4.5 T: 2°CAssay Description:A synthetic APP substrate that can be cleaved by beta-secretase having N-terminal biotin and made fluorescent by the covalent attachment of Oregon Gr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2016
Entry Details
US Patent

TargetBeta-secretase 1(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 202050BDBM202050(US9233981, 11)
Affinity DataIC50: 21nMpH: 4.5 T: 2°CAssay Description:A synthetic APP substrate that can be cleaved by beta-secretase having N-terminal biotin and made fluorescent by the covalent attachment of Oregon Gr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2016
Entry Details
US Patent

TargetBeta-secretase 1(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 202062BDBM202062(US9233981, 25 | US9233981, 24)
Affinity DataIC50: 22nMpH: 4.5 T: 2°CAssay Description:A synthetic APP substrate that can be cleaved by beta-secretase having N-terminal biotin and made fluorescent by the covalent attachment of Oregon Gr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2016
Entry Details
US Patent

TargetBeta-secretase 1(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 202041BDBM202041(US9233981, 2)
Affinity DataIC50: 22nMpH: 4.5 T: 2°CAssay Description:A synthetic APP substrate that can be cleaved by beta-secretase having N-terminal biotin and made fluorescent by the covalent attachment of Oregon Gr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2016
Entry Details
US Patent

TargetBeta-secretase 1(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 202045BDBM202045(US9233981, 6)
Affinity DataIC50: 24nMpH: 4.5 T: 2°CAssay Description:A synthetic APP substrate that can be cleaved by beta-secretase having N-terminal biotin and made fluorescent by the covalent attachment of Oregon Gr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2016
Entry Details
US Patent

TargetBeta-secretase 1(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 202069BDBM202069(US9233981, 31)
Affinity DataIC50: 28nMpH: 4.5 T: 2°CAssay Description:A synthetic APP substrate that can be cleaved by beta-secretase having N-terminal biotin and made fluorescent by the covalent attachment of Oregon Gr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2016
Entry Details
US Patent

TargetBeta-secretase 1(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 202054BDBM202054(US9233981, 16)
Affinity DataIC50: 29nMpH: 4.5 T: 2°CAssay Description:A synthetic APP substrate that can be cleaved by beta-secretase having N-terminal biotin and made fluorescent by the covalent attachment of Oregon Gr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2016
Entry Details
US Patent

TargetBeta-secretase 1(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 202043BDBM202043(US9233981, 4)
Affinity DataIC50: 39nMpH: 4.5 T: 2°CAssay Description:A synthetic APP substrate that can be cleaved by beta-secretase having N-terminal biotin and made fluorescent by the covalent attachment of Oregon Gr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2016
Entry Details
US Patent

TargetBeta-secretase 1(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 202068BDBM202068(US9233981, 30)
Affinity DataIC50: 42nMpH: 4.5 T: 2°CAssay Description:A synthetic APP substrate that can be cleaved by beta-secretase having N-terminal biotin and made fluorescent by the covalent attachment of Oregon Gr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2016
Entry Details
US Patent

TargetBeta-secretase 1(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 202057BDBM202057(US9233981, 19)
Affinity DataIC50: 44nMpH: 4.5 T: 2°CAssay Description:A synthetic APP substrate that can be cleaved by beta-secretase having N-terminal biotin and made fluorescent by the covalent attachment of Oregon Gr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2016
Entry Details
US Patent

TargetBeta-secretase 1(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 202058BDBM202058(US9233981, 20)
Affinity DataIC50: 83nMpH: 4.5 T: 2°CAssay Description:A synthetic APP substrate that can be cleaved by beta-secretase having N-terminal biotin and made fluorescent by the covalent attachment of Oregon Gr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2016
Entry Details
US Patent

TargetBeta-secretase 1(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 202042BDBM202042(US9233981, 3)
Affinity DataIC50: 86nMpH: 4.5 T: 2°CAssay Description:A synthetic APP substrate that can be cleaved by beta-secretase having N-terminal biotin and made fluorescent by the covalent attachment of Oregon Gr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2016
Entry Details
US Patent

TargetBeta-secretase 1(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 202052BDBM202052(US9233981, 13)
Affinity DataIC50: 97nMpH: 4.5 T: 2°CAssay Description:A synthetic APP substrate that can be cleaved by beta-secretase having N-terminal biotin and made fluorescent by the covalent attachment of Oregon Gr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2016
Entry Details
US Patent

TargetBeta-secretase 1(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 202067BDBM202067(US9233981, 29)
Affinity DataIC50: 99nMpH: 4.5 T: 2°CAssay Description:A synthetic APP substrate that can be cleaved by beta-secretase having N-terminal biotin and made fluorescent by the covalent attachment of Oregon Gr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2016
Entry Details
US Patent

TargetBeta-secretase 1(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 202062BDBM202062(US9233981, 25 | US9233981, 24)
Affinity DataIC50: 161nMpH: 4.5 T: 2°CAssay Description:A synthetic APP substrate that can be cleaved by beta-secretase having N-terminal biotin and made fluorescent by the covalent attachment of Oregon Gr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2016
Entry Details
US Patent

TargetBeta-secretase 1(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 202066BDBM202066(US9233981, 28)
Affinity DataIC50: 210nMpH: 4.5 T: 2°CAssay Description:A synthetic APP substrate that can be cleaved by beta-secretase having N-terminal biotin and made fluorescent by the covalent attachment of Oregon Gr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2016
Entry Details
US Patent

TargetBeta-secretase 1(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 202056BDBM202056(US9233981, 18)
Affinity DataIC50: 214nMpH: 4.5 T: 2°CAssay Description:A synthetic APP substrate that can be cleaved by beta-secretase having N-terminal biotin and made fluorescent by the covalent attachment of Oregon Gr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2016
Entry Details
US Patent

TargetBeta-secretase 1(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 202059BDBM202059(US9233981, 21)
Affinity DataIC50: 335nMpH: 4.5 T: 2°CAssay Description:A synthetic APP substrate that can be cleaved by beta-secretase having N-terminal biotin and made fluorescent by the covalent attachment of Oregon Gr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2016
Entry Details
US Patent

TargetBeta-secretase 1(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 202060BDBM202060(US9233981, 22)
Affinity DataIC50: 397nMpH: 4.5 T: 2°CAssay Description:A synthetic APP substrate that can be cleaved by beta-secretase having N-terminal biotin and made fluorescent by the covalent attachment of Oregon Gr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2016
Entry Details
US Patent

TargetBeta-secretase 1(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 202046BDBM202046(US9233981, 7)
Affinity DataIC50: 970nMpH: 4.5 T: 2°CAssay Description:A synthetic APP substrate that can be cleaved by beta-secretase having N-terminal biotin and made fluorescent by the covalent attachment of Oregon Gr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2016
Entry Details
US Patent

TargetBeta-secretase 1(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 202055BDBM202055(US9233981, 17)
Affinity DataIC50: 2.21E+3nMpH: 4.5 T: 2°CAssay Description:A synthetic APP substrate that can be cleaved by beta-secretase having N-terminal biotin and made fluorescent by the covalent attachment of Oregon Gr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2016
Entry Details
US Patent