Compile Data Set for Download or QSAR
Report error Found 359 Enz. Inhib. hit(s) with all data for entry = 7659
TargetBcl-2-like protein 1(Human)
Abbvie

US Patent
LigandChemical structure of BindingDB Monomer ID 209160BDBM209160(US9266877, 106)
Affinity DataKi:  0.100nM ΔG°:  -57.1kJ/moleT: 2°CAssay Description:The measurement of competition of compounds of Formula (I) with F-Bak for a Bcl-2 family protein (Bcl-xL) binding site using a Time Resolved Fluoresc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2017
Entry Details
US Patent

TargetBcl-2-like protein 1(Human)
Abbvie

US Patent
LigandChemical structure of BindingDB Monomer ID 209156BDBM209156(US9266877, 102)
Affinity DataKi: <0.100nM ΔG°: <-57.1kJ/moleT: 2°CAssay Description:The measurement of competition of compounds of Formula (I) with F-Bak for a Bcl-2 family protein (Bcl-xL) binding site using a Time Resolved Fluoresc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2017
Entry Details
US Patent

TargetBcl-2-like protein 1(Human)
Abbvie

US Patent
LigandChemical structure of BindingDB Monomer ID 209170BDBM209170(US9266877, 116)
Affinity DataKi: <0.100nM ΔG°: <-57.1kJ/moleT: 2°CAssay Description:The measurement of competition of compounds of Formula (I) with F-Bak for a Bcl-2 family protein (Bcl-xL) binding site using a Time Resolved Fluoresc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2017
Entry Details
US Patent

TargetBcl-2-like protein 1(Human)
Abbvie

US Patent
LigandChemical structure of BindingDB Monomer ID 209175BDBM209175(US9266877, 121)
Affinity DataKi:  0.100nM ΔG°:  -57.1kJ/moleT: 2°CAssay Description:The measurement of competition of compounds of Formula (I) with F-Bak for a Bcl-2 family protein (Bcl-xL) binding site using a Time Resolved Fluoresc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2017
Entry Details
US Patent

TargetBcl-2-like protein 1(Human)
Abbvie

US Patent
LigandChemical structure of BindingDB Monomer ID 209178BDBM209178(US9266877, 124)
Affinity DataKi: <0.100nM ΔG°: <-57.1kJ/moleT: 2°CAssay Description:The measurement of competition of compounds of Formula (I) with F-Bak for a Bcl-2 family protein (Bcl-xL) binding site using a Time Resolved Fluoresc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2017
Entry Details
US Patent

TargetBcl-2-like protein 1(Human)
Abbvie

US Patent
LigandChemical structure of BindingDB Monomer ID 209177BDBM209177(US9266877, 123)
Affinity DataKi: <0.100nM ΔG°: <-57.1kJ/moleT: 2°CAssay Description:The measurement of competition of compounds of Formula (I) with F-Bak for a Bcl-2 family protein (Bcl-xL) binding site using a Time Resolved Fluoresc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2017
Entry Details
US Patent

TargetBcl-2-like protein 1(Human)
Abbvie

US Patent
LigandChemical structure of BindingDB Monomer ID 209171BDBM209171(US9266877, 117)
Affinity DataKi: <0.100nM ΔG°: <-57.1kJ/moleT: 2°CAssay Description:The measurement of competition of compounds of Formula (I) with F-Bak for a Bcl-2 family protein (Bcl-xL) binding site using a Time Resolved Fluoresc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2017
Entry Details
US Patent

TargetBcl-2-like protein 1(Human)
Abbvie

US Patent
LigandChemical structure of BindingDB Monomer ID 209173BDBM209173(US9266877, 119)
Affinity DataKi: <0.100nM ΔG°: <-57.1kJ/moleT: 2°CAssay Description:The measurement of competition of compounds of Formula (I) with F-Bak for a Bcl-2 family protein (Bcl-xL) binding site using a Time Resolved Fluoresc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2017
Entry Details
US Patent

TargetBcl-2-like protein 1(Human)
Abbvie

US Patent
LigandChemical structure of BindingDB Monomer ID 209184BDBM209184(US9266877, 130)
Affinity DataKi: <0.100nM ΔG°: <-57.1kJ/moleT: 2°CAssay Description:The measurement of competition of compounds of Formula (I) with F-Bak for a Bcl-2 family protein (Bcl-xL) binding site using a Time Resolved Fluoresc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2017
Entry Details
US Patent

TargetBcl-2-like protein 1(Human)
Abbvie

US Patent
LigandChemical structure of BindingDB Monomer ID 209183BDBM209183(US9266877, 129)
Affinity DataKi: <0.100nM ΔG°: <-57.1kJ/moleT: 2°CAssay Description:The measurement of competition of compounds of Formula (I) with F-Bak for a Bcl-2 family protein (Bcl-xL) binding site using a Time Resolved Fluoresc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2017
Entry Details
US Patent

TargetBcl-2-like protein 1(Human)
Abbvie

US Patent
LigandChemical structure of BindingDB Monomer ID 209185BDBM209185(US9266877, 131)
Affinity DataKi: <0.100nM ΔG°: <-57.1kJ/moleT: 2°CAssay Description:The measurement of competition of compounds of Formula (I) with F-Bak for a Bcl-2 family protein (Bcl-xL) binding site using a Time Resolved Fluoresc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2017
Entry Details
US Patent

TargetBcl-2-like protein 1(Human)
Abbvie

US Patent
LigandChemical structure of BindingDB Monomer ID 209192BDBM209192(US9266877, 138)
Affinity DataKi: <0.100nM ΔG°: <-57.1kJ/moleT: 2°CAssay Description:The measurement of competition of compounds of Formula (I) with F-Bak for a Bcl-2 family protein (Bcl-xL) binding site using a Time Resolved Fluoresc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2017
Entry Details
US Patent

TargetBcl-2-like protein 1(Human)
Abbvie

US Patent
LigandChemical structure of BindingDB Monomer ID 209188BDBM209188(US9266877, 134)
Affinity DataKi: <0.100nM ΔG°: <-57.1kJ/moleT: 2°CAssay Description:The measurement of competition of compounds of Formula (I) with F-Bak for a Bcl-2 family protein (Bcl-xL) binding site using a Time Resolved Fluoresc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2017
Entry Details
US Patent

TargetBcl-2-like protein 1(Human)
Abbvie

US Patent
LigandChemical structure of BindingDB Monomer ID 209200BDBM209200(US9266877, 146)
Affinity DataKi: <0.100nM ΔG°: <-57.1kJ/moleT: 2°CAssay Description:The measurement of competition of compounds of Formula (I) with F-Bak for a Bcl-2 family protein (Bcl-xL) binding site using a Time Resolved Fluoresc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2017
Entry Details
US Patent

TargetBcl-2-like protein 1(Human)
Abbvie

US Patent
LigandChemical structure of BindingDB Monomer ID 209199BDBM209199(US9266877, 145)
Affinity DataKi: <0.100nM ΔG°: <-57.1kJ/moleT: 2°CAssay Description:The measurement of competition of compounds of Formula (I) with F-Bak for a Bcl-2 family protein (Bcl-xL) binding site using a Time Resolved Fluoresc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2017
Entry Details
US Patent

TargetBcl-2-like protein 1(Human)
Abbvie

US Patent
LigandChemical structure of BindingDB Monomer ID 209202BDBM209202(US9266877, 148)
Affinity DataKi: <0.100nM ΔG°: <-57.1kJ/moleT: 2°CAssay Description:The measurement of competition of compounds of Formula (I) with F-Bak for a Bcl-2 family protein (Bcl-xL) binding site using a Time Resolved Fluoresc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2017
Entry Details
US Patent

TargetBcl-2-like protein 1(Human)
Abbvie

US Patent
LigandChemical structure of BindingDB Monomer ID 209201BDBM209201(US9266877, 147)
Affinity DataKi: <0.100nM ΔG°: <-57.1kJ/moleT: 2°CAssay Description:The measurement of competition of compounds of Formula (I) with F-Bak for a Bcl-2 family protein (Bcl-xL) binding site using a Time Resolved Fluoresc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2017
Entry Details
US Patent

TargetBcl-2-like protein 1(Human)
Abbvie

US Patent
LigandChemical structure of BindingDB Monomer ID 209198BDBM209198(US9266877, 144)
Affinity DataKi: <0.100nM ΔG°: <-57.1kJ/moleT: 2°CAssay Description:The measurement of competition of compounds of Formula (I) with F-Bak for a Bcl-2 family protein (Bcl-xL) binding site using a Time Resolved Fluoresc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2017
Entry Details
US Patent

TargetBcl-2-like protein 1(Human)
Abbvie

US Patent
LigandChemical structure of BindingDB Monomer ID 209197BDBM209197(US9266877, 143)
Affinity DataKi: <0.100nM ΔG°: <-57.1kJ/moleT: 2°CAssay Description:The measurement of competition of compounds of Formula (I) with F-Bak for a Bcl-2 family protein (Bcl-xL) binding site using a Time Resolved Fluoresc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2017
Entry Details
US Patent

TargetBcl-2-like protein 1(Human)
Abbvie

US Patent
LigandChemical structure of BindingDB Monomer ID 209208BDBM209208(US9266877, 154)
Affinity DataKi: <0.100nM ΔG°: <-57.1kJ/moleT: 2°CAssay Description:The measurement of competition of compounds of Formula (I) with F-Bak for a Bcl-2 family protein (Bcl-xL) binding site using a Time Resolved Fluoresc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2017
Entry Details
US Patent

TargetBcl-2-like protein 1(Human)
Abbvie

US Patent
LigandChemical structure of BindingDB Monomer ID 209209BDBM209209(US9266877, 155)
Affinity DataKi: <0.100nM ΔG°: <-57.1kJ/moleT: 2°CAssay Description:The measurement of competition of compounds of Formula (I) with F-Bak for a Bcl-2 family protein (Bcl-xL) binding site using a Time Resolved Fluoresc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2017
Entry Details
US Patent

TargetBcl-2-like protein 1(Human)
Abbvie

US Patent
LigandChemical structure of BindingDB Monomer ID 209206BDBM209206(US9266877, 152)
Affinity DataKi: <0.100nM ΔG°: <-57.1kJ/moleT: 2°CAssay Description:The measurement of competition of compounds of Formula (I) with F-Bak for a Bcl-2 family protein (Bcl-xL) binding site using a Time Resolved Fluoresc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2017
Entry Details
US Patent

TargetBcl-2-like protein 1(Human)
Abbvie

US Patent
LigandChemical structure of BindingDB Monomer ID 209205BDBM209205(US9266877, 151)
Affinity DataKi: <0.100nM ΔG°: <-57.1kJ/moleT: 2°CAssay Description:The measurement of competition of compounds of Formula (I) with F-Bak for a Bcl-2 family protein (Bcl-xL) binding site using a Time Resolved Fluoresc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2017
Entry Details
US Patent

TargetBcl-2-like protein 1(Human)
Abbvie

US Patent
LigandChemical structure of BindingDB Monomer ID 209216BDBM209216(US9266877, 162)
Affinity DataKi: <0.100nM ΔG°: <-57.1kJ/moleT: 2°CAssay Description:The measurement of competition of compounds of Formula (I) with F-Bak for a Bcl-2 family protein (Bcl-xL) binding site using a Time Resolved Fluoresc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2017
Entry Details
US Patent

TargetBcl-2-like protein 1(Human)
Abbvie

US Patent
LigandChemical structure of BindingDB Monomer ID 209215BDBM209215(US9266877, 161)
Affinity DataKi: <0.100nM ΔG°: <-57.1kJ/moleT: 2°CAssay Description:The measurement of competition of compounds of Formula (I) with F-Bak for a Bcl-2 family protein (Bcl-xL) binding site using a Time Resolved Fluoresc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2017
Entry Details
US Patent

TargetBcl-2-like protein 1(Human)
Abbvie

US Patent
LigandChemical structure of BindingDB Monomer ID 209218BDBM209218(US9266877, 164)
Affinity DataKi: <0.100nM ΔG°: <-57.1kJ/moleT: 2°CAssay Description:The measurement of competition of compounds of Formula (I) with F-Bak for a Bcl-2 family protein (Bcl-xL) binding site using a Time Resolved Fluoresc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2017
Entry Details
US Patent

TargetBcl-2-like protein 1(Human)
Abbvie

US Patent
LigandChemical structure of BindingDB Monomer ID 209212BDBM209212(US9266877, 158)
Affinity DataKi: <0.100nM ΔG°: <-57.1kJ/moleT: 2°CAssay Description:The measurement of competition of compounds of Formula (I) with F-Bak for a Bcl-2 family protein (Bcl-xL) binding site using a Time Resolved Fluoresc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2017
Entry Details
US Patent

TargetBcl-2-like protein 1(Human)
Abbvie

US Patent
LigandChemical structure of BindingDB Monomer ID 209211BDBM209211(US9266877, 157)
Affinity DataKi: <0.100nM ΔG°: <-57.1kJ/moleT: 2°CAssay Description:The measurement of competition of compounds of Formula (I) with F-Bak for a Bcl-2 family protein (Bcl-xL) binding site using a Time Resolved Fluoresc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2017
Entry Details
US Patent

TargetBcl-2-like protein 1(Human)
Abbvie

US Patent
LigandChemical structure of BindingDB Monomer ID 209214BDBM209214(US9266877, 160)
Affinity DataKi: <0.100nM ΔG°: <-57.1kJ/moleT: 2°CAssay Description:The measurement of competition of compounds of Formula (I) with F-Bak for a Bcl-2 family protein (Bcl-xL) binding site using a Time Resolved Fluoresc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2017
Entry Details
US Patent

TargetBcl-2-like protein 1(Human)
Abbvie

US Patent
LigandChemical structure of BindingDB Monomer ID 209224BDBM209224(US9266877, 170)
Affinity DataKi: <0.100nM ΔG°: <-57.1kJ/moleT: 2°CAssay Description:The measurement of competition of compounds of Formula (I) with F-Bak for a Bcl-2 family protein (Bcl-xL) binding site using a Time Resolved Fluoresc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2017
Entry Details
US Patent

TargetBcl-2-like protein 1(Human)
Abbvie

US Patent
LigandChemical structure of BindingDB Monomer ID 209223BDBM209223(US9266877, 169)
Affinity DataKi: <0.100nM ΔG°: <-57.1kJ/moleT: 2°CAssay Description:The measurement of competition of compounds of Formula (I) with F-Bak for a Bcl-2 family protein (Bcl-xL) binding site using a Time Resolved Fluoresc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2017
Entry Details
US Patent

TargetBcl-2-like protein 1(Human)
Abbvie

US Patent
LigandChemical structure of BindingDB Monomer ID 209226BDBM209226(US9266877, 172)
Affinity DataKi: <0.100nM ΔG°: <-57.1kJ/moleT: 2°CAssay Description:The measurement of competition of compounds of Formula (I) with F-Bak for a Bcl-2 family protein (Bcl-xL) binding site using a Time Resolved Fluoresc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2017
Entry Details
US Patent

TargetBcl-2-like protein 1(Human)
Abbvie

US Patent
LigandChemical structure of BindingDB Monomer ID 209225BDBM209225(US9266877, 171)
Affinity DataKi: <0.100nM ΔG°: <-57.1kJ/moleT: 2°CAssay Description:The measurement of competition of compounds of Formula (I) with F-Bak for a Bcl-2 family protein (Bcl-xL) binding site using a Time Resolved Fluoresc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2017
Entry Details
US Patent

TargetBcl-2-like protein 1(Human)
Abbvie

US Patent
LigandChemical structure of BindingDB Monomer ID 209220BDBM209220(US9266877, 166)
Affinity DataKi: <0.100nM ΔG°: <-57.1kJ/moleT: 2°CAssay Description:The measurement of competition of compounds of Formula (I) with F-Bak for a Bcl-2 family protein (Bcl-xL) binding site using a Time Resolved Fluoresc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2017
Entry Details
US Patent

TargetBcl-2-like protein 1(Human)
Abbvie

US Patent
LigandChemical structure of BindingDB Monomer ID 209219BDBM209219(US9266877, 165)
Affinity DataKi: <0.100nM ΔG°: <-57.1kJ/moleT: 2°CAssay Description:The measurement of competition of compounds of Formula (I) with F-Bak for a Bcl-2 family protein (Bcl-xL) binding site using a Time Resolved Fluoresc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2017
Entry Details
US Patent

TargetBcl-2-like protein 1(Human)
Abbvie

US Patent
LigandChemical structure of BindingDB Monomer ID 209222BDBM209222(US9266877, 168)
Affinity DataKi: <0.100nM ΔG°: <-57.1kJ/moleT: 2°CAssay Description:The measurement of competition of compounds of Formula (I) with F-Bak for a Bcl-2 family protein (Bcl-xL) binding site using a Time Resolved Fluoresc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2017
Entry Details
US Patent

TargetBcl-2-like protein 1(Human)
Abbvie

US Patent
LigandChemical structure of BindingDB Monomer ID 209221BDBM209221(US9266877, 167)
Affinity DataKi: <0.100nM ΔG°: <-57.1kJ/moleT: 2°CAssay Description:The measurement of competition of compounds of Formula (I) with F-Bak for a Bcl-2 family protein (Bcl-xL) binding site using a Time Resolved Fluoresc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2017
Entry Details
US Patent

TargetBcl-2-like protein 1(Human)
Abbvie

US Patent
LigandChemical structure of BindingDB Monomer ID 209232BDBM209232(US9266877, 178)
Affinity DataKi: <0.100nM ΔG°: <-57.1kJ/moleT: 2°CAssay Description:The measurement of competition of compounds of Formula (I) with F-Bak for a Bcl-2 family protein (Bcl-xL) binding site using a Time Resolved Fluoresc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2017
Entry Details
US Patent

TargetBcl-2-like protein 1(Human)
Abbvie

US Patent
LigandChemical structure of BindingDB Monomer ID 209231BDBM209231(US9266877, 177)
Affinity DataKi: <0.100nM ΔG°: <-57.1kJ/moleT: 2°CAssay Description:The measurement of competition of compounds of Formula (I) with F-Bak for a Bcl-2 family protein (Bcl-xL) binding site using a Time Resolved Fluoresc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2017
Entry Details
US Patent

TargetBcl-2-like protein 1(Human)
Abbvie

US Patent
LigandChemical structure of BindingDB Monomer ID 209235BDBM209235(US9266877, 181)
Affinity DataKi: <0.100nM ΔG°: <-57.1kJ/moleT: 2°CAssay Description:The measurement of competition of compounds of Formula (I) with F-Bak for a Bcl-2 family protein (Bcl-xL) binding site using a Time Resolved Fluoresc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2017
Entry Details
US Patent

TargetBcl-2-like protein 1(Human)
Abbvie

US Patent
LigandChemical structure of BindingDB Monomer ID 209233BDBM209233(US9266877, 179)
Affinity DataKi: <0.100nM ΔG°: <-57.1kJ/moleT: 2°CAssay Description:The measurement of competition of compounds of Formula (I) with F-Bak for a Bcl-2 family protein (Bcl-xL) binding site using a Time Resolved Fluoresc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2017
Entry Details
US Patent

TargetBcl-2-like protein 1(Human)
Abbvie

US Patent
LigandChemical structure of BindingDB Monomer ID 209228BDBM209228(US9266877, 174)
Affinity DataKi: <0.100nM ΔG°: <-57.1kJ/moleT: 2°CAssay Description:The measurement of competition of compounds of Formula (I) with F-Bak for a Bcl-2 family protein (Bcl-xL) binding site using a Time Resolved Fluoresc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2017
Entry Details
US Patent

TargetBcl-2-like protein 1(Human)
Abbvie

US Patent
LigandChemical structure of BindingDB Monomer ID 209227BDBM209227(US9266877, 173)
Affinity DataKi: <0.100nM ΔG°: <-57.1kJ/moleT: 2°CAssay Description:The measurement of competition of compounds of Formula (I) with F-Bak for a Bcl-2 family protein (Bcl-xL) binding site using a Time Resolved Fluoresc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2017
Entry Details
US Patent

TargetBcl-2-like protein 1(Human)
Abbvie

US Patent
LigandChemical structure of BindingDB Monomer ID 209230BDBM209230(US9266877, 176)
Affinity DataKi: <0.100nM ΔG°: <-57.1kJ/moleT: 2°CAssay Description:The measurement of competition of compounds of Formula (I) with F-Bak for a Bcl-2 family protein (Bcl-xL) binding site using a Time Resolved Fluoresc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2017
Entry Details
US Patent

TargetBcl-2-like protein 1(Human)
Abbvie

US Patent
LigandChemical structure of BindingDB Monomer ID 209229BDBM209229(US9266877, 175)
Affinity DataKi: <0.100nM ΔG°: <-57.1kJ/moleT: 2°CAssay Description:The measurement of competition of compounds of Formula (I) with F-Bak for a Bcl-2 family protein (Bcl-xL) binding site using a Time Resolved Fluoresc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2017
Entry Details
US Patent

TargetBcl-2-like protein 1(Human)
Abbvie

US Patent
LigandChemical structure of BindingDB Monomer ID 209240BDBM209240(US9266877, 186)
Affinity DataKi: <0.100nM ΔG°: <-57.1kJ/moleT: 2°CAssay Description:The measurement of competition of compounds of Formula (I) with F-Bak for a Bcl-2 family protein (Bcl-xL) binding site using a Time Resolved Fluoresc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2017
Entry Details
US Patent

TargetBcl-2-like protein 1(Human)
Abbvie

US Patent
LigandChemical structure of BindingDB Monomer ID 209239BDBM209239(US9266877, 185)
Affinity DataKi: <0.100nM ΔG°: <-57.1kJ/moleT: 2°CAssay Description:The measurement of competition of compounds of Formula (I) with F-Bak for a Bcl-2 family protein (Bcl-xL) binding site using a Time Resolved Fluoresc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2017
Entry Details
US Patent

TargetBcl-2-like protein 1(Human)
Abbvie

US Patent
LigandChemical structure of BindingDB Monomer ID 209238BDBM209238(US9266877, 184)
Affinity DataKi: <0.100nM ΔG°: <-57.1kJ/moleT: 2°CAssay Description:The measurement of competition of compounds of Formula (I) with F-Bak for a Bcl-2 family protein (Bcl-xL) binding site using a Time Resolved Fluoresc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2017
Entry Details
US Patent

TargetBcl-2-like protein 1(Mouse)
Abbvie

US Patent
LigandChemical structure of BindingDB Monomer ID 209227BDBM209227(US9266877, 173)
Affinity DataEC50:  0.100nMAssay Description:The efficacy of the compounds of Formula (I) can also be determined in cell-based killing assays using a variety of cell lines and mouse tumor models...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2017
Entry Details
US Patent

TargetBcl-2-like protein 1(Human)
Abbvie

US Patent
LigandChemical structure of BindingDB Monomer ID 209168BDBM209168(US9266877, 114)
Affinity DataKi:  0.200nM ΔG°:  -55.4kJ/moleT: 2°CAssay Description:The measurement of competition of compounds of Formula (I) with F-Bak for a Bcl-2 family protein (Bcl-xL) binding site using a Time Resolved Fluoresc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2017
Entry Details
US Patent

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