Compile Data Set for Download or QSAR
Report error Found 551 Enz. Inhib. hit(s) with all data for entry = 7737
TargetTyrosine-protein kinase ABL1 [64-515](Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 213682BDBM213682(US9278981, 274)
Affinity DataIC50: 0.100nMpH: 7.5 T: 2°CAssay Description:For determination of ABL kinase activity, the radiometric filter-binding assay was used. The assay was performed by mixing 10 uL of the compound pre-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2017
Entry Details
US Patent

TargetTyrosine-protein kinase ABL1 [64-515](Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 213677BDBM213677(US9278981, 269)
Affinity DataIC50: 0.100nMpH: 7.5 T: 2°CAssay Description:For determination of ABL kinase activity, the radiometric filter-binding assay was used. The assay was performed by mixing 10 uL of the compound pre-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2017
Entry Details
US Patent

TargetTyrosine-protein kinase ABL1 [64-515](Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 213662BDBM213662(US9278981, 254)
Affinity DataIC50: 0.100nMpH: 7.5 T: 2°CAssay Description:For determination of ABL kinase activity, the radiometric filter-binding assay was used. The assay was performed by mixing 10 uL of the compound pre-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2017
Entry Details
US Patent

TargetTyrosine-protein kinase ABL1 [64-515](Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 213659BDBM213659(US9278981, 251)
Affinity DataIC50: 0.100nMpH: 7.5 T: 2°CAssay Description:For determination of ABL kinase activity, the radiometric filter-binding assay was used. The assay was performed by mixing 10 uL of the compound pre-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2017
Entry Details
US Patent

TargetTyrosine-protein kinase ABL1 [64-515](Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 213671BDBM213671(US9278981, 263)
Affinity DataIC50: 0.130nMpH: 7.5 T: 2°CAssay Description:The assay plates were prepared by addition of 50 nL per well of compound solution in 90% DMSO. The kinase reactions were started by stepwise addition...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2017
Entry Details
US Patent

TargetTyrosine-protein kinase ABL1 [64-515](Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 213673BDBM213673(US9278981, 265)
Affinity DataIC50: 0.130nMpH: 7.5 T: 2°CAssay Description:The assay plates were prepared by addition of 50 nL per well of compound solution in 90% DMSO. The kinase reactions were started by stepwise addition...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2017
Entry Details
US Patent

TargetTyrosine-protein kinase ABL1 [64-515](Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 213667BDBM213667(US9278981, 259)
Affinity DataIC50: 0.130nMpH: 7.5 T: 2°CAssay Description:The assay plates were prepared by addition of 50 nL per well of compound solution in 90% DMSO. The kinase reactions were started by stepwise addition...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2017
Entry Details
US Patent

TargetTyrosine-protein kinase ABL1 [64-515](Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 213496BDBM213496(US9278981, 88)
Affinity DataIC50: 0.130nMpH: 7.5 T: 2°CAssay Description:The assay plates were prepared by addition of 50 nL per well of compound solution in 90% DMSO. The kinase reactions were started by stepwise addition...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2017
Entry Details
US Patent

TargetTyrosine-protein kinase ABL1 [64-515](Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 213559BDBM213559(US9278981, 151)
Affinity DataIC50: 0.130nMpH: 7.5 T: 2°CAssay Description:The assay plates were prepared by addition of 50 nL per well of compound solution in 90% DMSO. The kinase reactions were started by stepwise addition...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2017
Entry Details
US Patent

TargetTyrosine-protein kinase ABL1 [64-515](Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 213603BDBM213603(US9278981, 195)
Affinity DataIC50: 0.130nMpH: 7.5 T: 2°CAssay Description:The assay plates were prepared by addition of 50 nL per well of compound solution in 90% DMSO. The kinase reactions were started by stepwise addition...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2017
Entry Details
US Patent

TargetTyrosine-protein kinase ABL1 [64-515](Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 213581BDBM213581(US9278981, 173)
Affinity DataIC50: 0.130nMpH: 7.5 T: 2°CAssay Description:The assay plates were prepared by addition of 50 nL per well of compound solution in 90% DMSO. The kinase reactions were started by stepwise addition...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2017
Entry Details
US Patent

TargetTyrosine-protein kinase ABL1 [64-515](Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 213613BDBM213613(US9278981, 205)
Affinity DataIC50: 0.130nMpH: 7.5 T: 2°CAssay Description:The assay plates were prepared by addition of 50 nL per well of compound solution in 90% DMSO. The kinase reactions were started by stepwise addition...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2017
Entry Details
US Patent

TargetTyrosine-protein kinase ABL1 [64-515](Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 213578BDBM213578(US9278981, 170)
Affinity DataIC50: 0.130nMpH: 7.5 T: 2°CAssay Description:The assay plates were prepared by addition of 50 nL per well of compound solution in 90% DMSO. The kinase reactions were started by stepwise addition...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2017
Entry Details
US Patent

TargetTyrosine-protein kinase ABL1 [64-515](Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 213677BDBM213677(US9278981, 269)
Affinity DataIC50: 0.130nMpH: 7.5 T: 2°CAssay Description:The assay plates were prepared by addition of 50 nL per well of compound solution in 90% DMSO. The kinase reactions were started by stepwise addition...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2017
Entry Details
US Patent

TargetTyrosine-protein kinase ABL1 [64-515](Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 213579BDBM213579(US9278981, 171)
Affinity DataIC50: 0.130nMpH: 7.5 T: 2°CAssay Description:The assay plates were prepared by addition of 50 nL per well of compound solution in 90% DMSO. The kinase reactions were started by stepwise addition...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2017
Entry Details
US Patent

TargetTyrosine-protein kinase ABL1 [64-515](Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 213655BDBM213655(US9278981, 247)
Affinity DataIC50: 0.130nMpH: 7.5 T: 2°CAssay Description:The assay plates were prepared by addition of 50 nL per well of compound solution in 90% DMSO. The kinase reactions were started by stepwise addition...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2017
Entry Details
US Patent

TargetTyrosine-protein kinase ABL1 [64-515](Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 213656BDBM213656(US9278981, 248)
Affinity DataIC50: 0.130nMpH: 7.5 T: 2°CAssay Description:The assay plates were prepared by addition of 50 nL per well of compound solution in 90% DMSO. The kinase reactions were started by stepwise addition...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2017
Entry Details
US Patent

TargetTyrosine-protein kinase ABL1 [64-515](Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 213486BDBM213486(US9278981, 78)
Affinity DataIC50: 0.200nMpH: 7.5 T: 2°CAssay Description:The assay plates were prepared by addition of 50 nL per well of compound solution in 90% DMSO. The kinase reactions were started by stepwise addition...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2017
Entry Details
US Patent

TargetTyrosine-protein kinase ABL1 [64-515](Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 213583BDBM213583(US9278981, 175)
Affinity DataIC50: 0.200nMpH: 7.5 T: 2°CAssay Description:The assay plates were prepared by addition of 50 nL per well of compound solution in 90% DMSO. The kinase reactions were started by stepwise addition...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2017
Entry Details
US Patent

TargetTyrosine-protein kinase ABL1 [64-515](Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 213594BDBM213594(US9278981, 186)
Affinity DataIC50: 0.200nMpH: 7.5 T: 2°CAssay Description:The assay plates were prepared by addition of 50 nL per well of compound solution in 90% DMSO. The kinase reactions were started by stepwise addition...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2017
Entry Details
US Patent

TargetTyrosine-protein kinase ABL1 [64-515](Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 213631BDBM213631(US9278981, 223)
Affinity DataIC50: 0.200nMpH: 7.5 T: 2°CAssay Description:For determination of ABL kinase activity, the radiometric filter-binding assay was used. The assay was performed by mixing 10 uL of the compound pre-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2017
Entry Details
US Patent

TargetTyrosine-protein kinase ABL1 [64-515](Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 213593BDBM213593(US9278981, 185)
Affinity DataIC50: 0.200nMpH: 7.5 T: 2°CAssay Description:The assay plates were prepared by addition of 50 nL per well of compound solution in 90% DMSO. The kinase reactions were started by stepwise addition...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2017
Entry Details
US Patent

TargetTyrosine-protein kinase ABL1 [64-515](Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 213596BDBM213596(US9278981, 188)
Affinity DataIC50: 0.200nMpH: 7.5 T: 2°CAssay Description:The assay plates were prepared by addition of 50 nL per well of compound solution in 90% DMSO. The kinase reactions were started by stepwise addition...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2017
Entry Details
US Patent

TargetTyrosine-protein kinase ABL1 [64-515](Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 213595BDBM213595(US9278981, 187)
Affinity DataIC50: 0.200nMpH: 7.5 T: 2°CAssay Description:The assay plates were prepared by addition of 50 nL per well of compound solution in 90% DMSO. The kinase reactions were started by stepwise addition...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2017
Entry Details
US Patent

TargetTyrosine-protein kinase ABL1 [64-515](Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 213589BDBM213589(US9278981, 181)
Affinity DataIC50: 0.200nMpH: 7.5 T: 2°CAssay Description:The assay plates were prepared by addition of 50 nL per well of compound solution in 90% DMSO. The kinase reactions were started by stepwise addition...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2017
Entry Details
US Patent

TargetTyrosine-protein kinase ABL1 [64-515](Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 213448BDBM213448(US9278981, 40)
Affinity DataIC50: 0.200nMpH: 7.5 T: 2°CAssay Description:For determination of ABL kinase activity, the radiometric filter-binding assay was used. The assay was performed by mixing 10 uL of the compound pre-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2017
Entry Details
US Patent

TargetTyrosine-protein kinase ABL1 [64-515](Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 213699BDBM213699(US9278981, 291)
Affinity DataIC50: 0.200nMpH: 7.5 T: 2°CAssay Description:The assay plates were prepared by addition of 50 nL per well of compound solution in 90% DMSO. The kinase reactions were started by stepwise addition...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2017
Entry Details
US Patent

TargetTyrosine-protein kinase ABL1 [64-515](Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 213707BDBM213707(US9278981, 299)
Affinity DataIC50: 0.300nMpH: 7.5 T: 2°CAssay Description:The assay plates were prepared by addition of 50 nL per well of compound solution in 90% DMSO. The kinase reactions were started by stepwise addition...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2017
Entry Details
US Patent

TargetTyrosine-protein kinase ABL1 [64-515](Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 213516BDBM213516(US9278981, 108)
Affinity DataIC50: 0.300nMpH: 7.5 T: 2°CAssay Description:The assay plates were prepared by addition of 50 nL per well of compound solution in 90% DMSO. The kinase reactions were started by stepwise addition...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2017
Entry Details
US Patent

TargetTyrosine-protein kinase ABL1 [64-515](Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 213580BDBM213580(US9278981, 172)
Affinity DataIC50: 0.300nMpH: 7.5 T: 2°CAssay Description:The assay plates were prepared by addition of 50 nL per well of compound solution in 90% DMSO. The kinase reactions were started by stepwise addition...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2017
Entry Details
US Patent

TargetTyrosine-protein kinase ABL1 [64-515](Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 213497BDBM213497(US9278981, 89)
Affinity DataIC50: 0.300nMpH: 7.5 T: 2°CAssay Description:The assay plates were prepared by addition of 50 nL per well of compound solution in 90% DMSO. The kinase reactions were started by stepwise addition...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2017
Entry Details
US Patent

TargetTyrosine-protein kinase ABL1 [64-515](Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 213688BDBM213688(US9278981, 280)
Affinity DataIC50: 0.300nMpH: 7.5 T: 2°CAssay Description:The assay plates were prepared by addition of 50 nL per well of compound solution in 90% DMSO. The kinase reactions were started by stepwise addition...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2017
Entry Details
US Patent

TargetTyrosine-protein kinase ABL1 [64-515](Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 213585BDBM213585(US9278981, 177)
Affinity DataIC50: 0.300nMpH: 7.5 T: 2°CAssay Description:The assay plates were prepared by addition of 50 nL per well of compound solution in 90% DMSO. The kinase reactions were started by stepwise addition...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2017
Entry Details
US Patent

TargetTyrosine-protein kinase ABL1 [64-515](Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 213548BDBM213548(US9278981, 140)
Affinity DataIC50: 0.400nMpH: 7.5 T: 2°CAssay Description:The assay plates were prepared by addition of 50 nL per well of compound solution in 90% DMSO. The kinase reactions were started by stepwise addition...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2017
Entry Details
US Patent

TargetTyrosine-protein kinase ABL1 [64-515](Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 213664BDBM213664(US9278981, 256)
Affinity DataIC50: 0.400nMpH: 7.5 T: 2°CAssay Description:The assay plates were prepared by addition of 50 nL per well of compound solution in 90% DMSO. The kinase reactions were started by stepwise addition...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2017
Entry Details
US Patent

TargetTyrosine-protein kinase ABL1 [64-515](Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 213625BDBM213625(US9278981, 217)
Affinity DataIC50: 0.400nMpH: 7.5 T: 2°CAssay Description:The assay plates were prepared by addition of 50 nL per well of compound solution in 90% DMSO. The kinase reactions were started by stepwise addition...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2017
Entry Details
US Patent

TargetTyrosine-protein kinase ABL1 [64-515](Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 213606BDBM213606(US9278981, 198)
Affinity DataIC50: 0.400nMpH: 7.5 T: 2°CAssay Description:The assay plates were prepared by addition of 50 nL per well of compound solution in 90% DMSO. The kinase reactions were started by stepwise addition...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2017
Entry Details
US Patent

TargetTyrosine-protein kinase ABL1 [64-515](Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 213601BDBM213601(US9278981, 193)
Affinity DataIC50: 0.400nMpH: 7.5 T: 2°CAssay Description:The assay plates were prepared by addition of 50 nL per well of compound solution in 90% DMSO. The kinase reactions were started by stepwise addition...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2017
Entry Details
US Patent

TargetTyrosine-protein kinase ABL1 [64-515](Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 213461BDBM213461(US9278981, 53)
Affinity DataIC50: 0.400nMpH: 7.5 T: 2°CAssay Description:The assay plates were prepared by addition of 50 nL per well of compound solution in 90% DMSO. The kinase reactions were started by stepwise addition...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2017
Entry Details
US Patent

TargetTyrosine-protein kinase ABL1 [64-515](Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 213525BDBM213525(US9278981, 117)
Affinity DataIC50: 0.400nMpH: 7.5 T: 2°CAssay Description:For determination of ABL kinase activity, the radiometric filter-binding assay was used. The assay was performed by mixing 10 uL of the compound pre-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2017
Entry Details
US Patent

TargetTyrosine-protein kinase ABL1 [64-515](Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 213676BDBM213676(US9278981, 268)
Affinity DataIC50: 0.400nMpH: 7.5 T: 2°CAssay Description:The assay plates were prepared by addition of 50 nL per well of compound solution in 90% DMSO. The kinase reactions were started by stepwise addition...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2017
Entry Details
US Patent

TargetTyrosine-protein kinase ABL1 [64-515](Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 213478BDBM213478(US9278981, 70)
Affinity DataIC50: 0.400nMpH: 7.5 T: 2°CAssay Description:The assay plates were prepared by addition of 50 nL per well of compound solution in 90% DMSO. The kinase reactions were started by stepwise addition...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2017
Entry Details
US Patent

TargetTyrosine-protein kinase ABL1 [64-515](Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 213586BDBM213586(US9278981, 178)
Affinity DataIC50: 0.400nMpH: 7.5 T: 2°CAssay Description:The assay plates were prepared by addition of 50 nL per well of compound solution in 90% DMSO. The kinase reactions were started by stepwise addition...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2017
Entry Details
US Patent

TargetTyrosine-protein kinase ABL1 [64-515](Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 213682BDBM213682(US9278981, 274)
Affinity DataIC50: 0.400nMpH: 7.5 T: 2°CAssay Description:The assay plates were prepared by addition of 50 nL per well of compound solution in 90% DMSO. The kinase reactions were started by stepwise addition...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2017
Entry Details
US Patent

TargetTyrosine-protein kinase ABL1 [64-515](Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 213474BDBM213474(US9278981, 66)
Affinity DataIC50: 0.400nMpH: 7.5 T: 2°CAssay Description:The assay plates were prepared by addition of 50 nL per well of compound solution in 90% DMSO. The kinase reactions were started by stepwise addition...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2017
Entry Details
US Patent

TargetTyrosine-protein kinase ABL1 [64-515](Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 213588BDBM213588(US9278981, 180)
Affinity DataIC50: 0.400nMpH: 7.5 T: 2°CAssay Description:The assay plates were prepared by addition of 50 nL per well of compound solution in 90% DMSO. The kinase reactions were started by stepwise addition...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2017
Entry Details
US Patent

TargetTyrosine-protein kinase ABL1 [64-515](Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 213598BDBM213598(US9278981, 190)
Affinity DataIC50: 0.5nMpH: 7.5 T: 2°CAssay Description:The assay plates were prepared by addition of 50 nL per well of compound solution in 90% DMSO. The kinase reactions were started by stepwise addition...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2017
Entry Details
US Patent

TargetTyrosine-protein kinase ABL1 [64-515](Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 213661BDBM213661(US9278981, 253)
Affinity DataIC50: 0.5nMpH: 7.5 T: 2°CAssay Description:The assay plates were prepared by addition of 50 nL per well of compound solution in 90% DMSO. The kinase reactions were started by stepwise addition...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2017
Entry Details
US Patent

TargetTyrosine-protein kinase ABL1 [64-515](Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 213660BDBM213660(US9278981, 252)
Affinity DataIC50: 0.5nMpH: 7.5 T: 2°CAssay Description:The assay plates were prepared by addition of 50 nL per well of compound solution in 90% DMSO. The kinase reactions were started by stepwise addition...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2017
Entry Details
US Patent

TargetTyrosine-protein kinase ABL1 [64-515](Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 213676BDBM213676(US9278981, 268)
Affinity DataIC50: 0.5nMpH: 7.5 T: 2°CAssay Description:For determination of ABL kinase activity, the radiometric filter-binding assay was used. The assay was performed by mixing 10 uL of the compound pre-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2017
Entry Details
US Patent

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