Compile Data Set for Download or QSAR
Report error Found 13 Enz. Inhib. hit(s) with all data for entry = 7698
TargetTyrosine-protein kinase SYK [2-635](Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 211959BDBM211959(US9290481, 3.1)
Affinity DataIC50: 0.5nMpH: 7.5 T: 2°CAssay Description:All assays were performed in 384 well microtiter plates. Each assay plate contained 8-point serial dilutions for 40 test compounds, as well as four 8...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/6/2017
Entry Details
US Patent

TargetTyrosine-protein kinase SYK [2-635](Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 211951BDBM211951(US9290481, 1.2)
Affinity DataIC50: 0.800nMpH: 7.5 T: 2°CAssay Description:All assays were performed in 384 well microtiter plates. Each assay plate contained 8-point serial dilutions for 40 test compounds, as well as four 8...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/6/2017
Entry Details
US Patent

TargetTyrosine-protein kinase SYK [2-635](Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 211960BDBM211960(US9290481, 4.2)
Affinity DataIC50: 1nMpH: 7.5 T: 2°CAssay Description:All assays were performed in 384 well microtiter plates. Each assay plate contained 8-point serial dilutions for 40 test compounds, as well as four 8...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/6/2017
Entry Details
US Patent

TargetTyrosine-protein kinase SYK [2-635](Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 50076187BDBM50076187(CHEMBL3416027 | US9290481, 1.4)
Affinity DataIC50: 1nMpH: 7.5 T: 2°CAssay Description:All assays were performed in 384 well microtiter plates. Each assay plate contained 8-point serial dilutions for 40 test compounds, as well as four 8...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/6/2017
Entry Details
US Patent

TargetTyrosine-protein kinase SYK [2-635](Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 50076189BDBM50076189(CHEMBL3416024 | US9290481, 4.1)
Affinity DataIC50: 2.70nMpH: 7.5 T: 2°CAssay Description:All assays were performed in 384 well microtiter plates. Each assay plate contained 8-point serial dilutions for 40 test compounds, as well as four 8...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/6/2017
Entry Details
US Patent

TargetTyrosine-protein kinase SYK [2-635](Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 211952BDBM211952(US9290481, 1.3)
Affinity DataIC50: 3.5nMpH: 7.5 T: 2°CAssay Description:All assays were performed in 384 well microtiter plates. Each assay plate contained 8-point serial dilutions for 40 test compounds, as well as four 8...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/6/2017
Entry Details
US Patent

TargetTyrosine-protein kinase SYK [2-635](Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 211958BDBM211958(US9290481, 2.6)
Affinity DataIC50: 4.60nMpH: 7.5 T: 2°CAssay Description:All assays were performed in 384 well microtiter plates. Each assay plate contained 8-point serial dilutions for 40 test compounds, as well as four 8...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/6/2017
Entry Details
US Patent

TargetTyrosine-protein kinase SYK [2-635](Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 211954BDBM211954(US9290481, 2.2)
Affinity DataIC50: 5.10nMpH: 7.5 T: 2°CAssay Description:All assays were performed in 384 well microtiter plates. Each assay plate contained 8-point serial dilutions for 40 test compounds, as well as four 8...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/6/2017
Entry Details
US Patent

TargetTyrosine-protein kinase SYK [2-635](Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 211955BDBM211955(US9290481, 2.3)
Affinity DataIC50: 11nMpH: 7.5 T: 2°CAssay Description:All assays were performed in 384 well microtiter plates. Each assay plate contained 8-point serial dilutions for 40 test compounds, as well as four 8...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/6/2017
Entry Details
US Patent

TargetTyrosine-protein kinase SYK [2-635](Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 211953BDBM211953(US9290481, 2.1)
Affinity DataIC50: 12nMpH: 7.5 T: 2°CAssay Description:All assays were performed in 384 well microtiter plates. Each assay plate contained 8-point serial dilutions for 40 test compounds, as well as four 8...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/6/2017
Entry Details
US Patent

TargetTyrosine-protein kinase SYK [2-635](Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 50076185BDBM50076185(CHEMBL3416026 | US9290481, 1.1)
Affinity DataIC50: 23nMpH: 7.5 T: 2°CAssay Description:All assays were performed in 384 well microtiter plates. Each assay plate contained 8-point serial dilutions for 40 test compounds, as well as four 8...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/6/2017
Entry Details
US Patent
PDB3D3D Structure (crystal)
TargetTyrosine-protein kinase SYK [2-635](Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 211957BDBM211957(US9290481, 2.5)
Affinity DataIC50: 30nMpH: 7.5 T: 2°CAssay Description:All assays were performed in 384 well microtiter plates. Each assay plate contained 8-point serial dilutions for 40 test compounds, as well as four 8...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/6/2017
Entry Details
US Patent

TargetTyrosine-protein kinase SYK [2-635](Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 211956BDBM211956(US9290481, 2.4)
Affinity DataIC50: 86nMpH: 7.5 T: 2°CAssay Description:All assays were performed in 384 well microtiter plates. Each assay plate contained 8-point serial dilutions for 40 test compounds, as well as four 8...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/6/2017
Entry Details
US Patent