Compile Data Set for Download or QSAR
Report error Found 722 Enz. Inhib. hit(s) with all data for entry = 7768
TargetBeta-secretase 1(Human)
Amgen

US Patent
LigandChemical structure of BindingDB Monomer ID 214844BDBM214844(US9296734, 45)
Affinity DataIC50: 0.5nMT: 2°CAssay Description:The cell-based assay measures inhibition or reduction of Aβ40 in conditioned medium of test compound treated cells expressing amyloid precursor ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2017
Entry Details
US Patent

TargetBeta-secretase 1(Human)
Amgen

US Patent
LigandChemical structure of BindingDB Monomer ID 214839BDBM214839(US9296734, 39)
Affinity DataIC50: 0.700nMpH: 4.2Assay Description:The assay buffer used in this screen is 0.05 M acetate, pH 4.2, 10% DMSO final, 100 uM genapol (which is a nonionic detergent, below its Critical Mic...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2017
Entry Details
US Patent

TargetBeta-secretase 1(Human)
Amgen

US Patent
LigandChemical structure of BindingDB Monomer ID 214961BDBM214961(US9296734, 155)
Affinity DataIC50: 0.870nMpH: 4.2Assay Description:The assay buffer used in this screen is 0.05 M acetate, pH 4.2, 10% DMSO final, 100 uM genapol (which is a nonionic detergent, below its Critical Mic...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2017
Entry Details
US Patent

TargetBeta-secretase 1(Human)
Amgen

US Patent
LigandChemical structure of BindingDB Monomer ID 215020BDBM215020(US9296734, 212)
Affinity DataIC50: 1nMT: 2°CAssay Description:The cell-based assay measures inhibition or reduction of Aβ40 in conditioned medium of test compound treated cells expressing amyloid precursor ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2017
Entry Details
US Patent

TargetBeta-secretase 1(Human)
Amgen

US Patent
LigandChemical structure of BindingDB Monomer ID 215026BDBM215026(US9296734, 218)
Affinity DataIC50: 1nMpH: 4.2Assay Description:The assay buffer used in this screen is 0.05 M acetate, pH 4.2, 10% DMSO final, 100 uM genapol (which is a nonionic detergent, below its Critical Mic...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2017
Entry Details
US Patent

TargetBeta-secretase 1(Human)
Amgen

US Patent
LigandChemical structure of BindingDB Monomer ID 214960BDBM214960(US9296734, 154)
Affinity DataIC50: 1.40nMpH: 4.2Assay Description:The assay buffer used in this screen is 0.05 M acetate, pH 4.2, 10% DMSO final, 100 uM genapol (which is a nonionic detergent, below its Critical Mic...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2017
Entry Details
US Patent

TargetBeta-secretase 1(Human)
Amgen

US Patent
LigandChemical structure of BindingDB Monomer ID 214997BDBM214997(US9296734, 190)
Affinity DataIC50: 2nMT: 2°CAssay Description:The cell-based assay measures inhibition or reduction of Aβ40 in conditioned medium of test compound treated cells expressing amyloid precursor ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2017
Entry Details
US Patent

TargetBeta-secretase 1(Human)
Amgen

US Patent
LigandChemical structure of BindingDB Monomer ID 215020BDBM215020(US9296734, 212)
Affinity DataIC50: 2nMpH: 4.2Assay Description:The assay buffer used in this screen is 0.05 M acetate, pH 4.2, 10% DMSO final, 100 uM genapol (which is a nonionic detergent, below its Critical Mic...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2017
Entry Details
US Patent

TargetBeta-secretase 1(Human)
Amgen

US Patent
LigandChemical structure of BindingDB Monomer ID 214997BDBM214997(US9296734, 190)
Affinity DataIC50: 2nMpH: 4.2Assay Description:The assay buffer used in this screen is 0.05 M acetate, pH 4.2, 10% DMSO final, 100 uM genapol (which is a nonionic detergent, below its Critical Mic...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2017
Entry Details
US Patent

TargetBeta-secretase 1(Human)
Amgen

US Patent
LigandChemical structure of BindingDB Monomer ID 214940BDBM214940(US9296734, 218)
Affinity DataIC50: 2nMT: 2°CAssay Description:The cell-based assay measures inhibition or reduction of Aβ40 in conditioned medium of test compound treated cells expressing amyloid precursor ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2017
Entry Details
US Patent

TargetBeta-secretase 1(Human)
Amgen

US Patent
LigandChemical structure of BindingDB Monomer ID 214835BDBM214835(US9296734, 35)
Affinity DataIC50: 2.30nMpH: 4.2Assay Description:The assay buffer used in this screen is 0.05 M acetate, pH 4.2, 10% DMSO final, 100 uM genapol (which is a nonionic detergent, below its Critical Mic...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2017
Entry Details
US Patent

TargetBeta-secretase 1(Human)
Amgen

US Patent
LigandChemical structure of BindingDB Monomer ID 214844BDBM214844(US9296734, 45)
Affinity DataIC50: 2.30nMpH: 4.2Assay Description:The assay buffer used in this screen is 0.05 M acetate, pH 4.2, 10% DMSO final, 100 uM genapol (which is a nonionic detergent, below its Critical Mic...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2017
Entry Details
US Patent

TargetBeta-secretase 1(Human)
Amgen

US Patent
LigandChemical structure of BindingDB Monomer ID 214872BDBM214872(US9296734, 73)
Affinity DataIC50: 2.5nMT: 2°CAssay Description:The cell-based assay measures inhibition or reduction of Aβ40 in conditioned medium of test compound treated cells expressing amyloid precursor ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2017
Entry Details
US Patent

TargetBeta-secretase 1(Human)
Amgen

US Patent
LigandChemical structure of BindingDB Monomer ID 214992BDBM214992(US9296734, 185)
Affinity DataIC50: 2.5nMT: 2°CAssay Description:The cell-based assay measures inhibition or reduction of Aβ40 in conditioned medium of test compound treated cells expressing amyloid precursor ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2017
Entry Details
US Patent

TargetBeta-secretase 1(Human)
Amgen

US Patent
LigandChemical structure of BindingDB Monomer ID 214970BDBM214970(US9296734, 163)
Affinity DataIC50: 2.80nMT: 2°CAssay Description:The cell-based assay measures inhibition or reduction of Aβ40 in conditioned medium of test compound treated cells expressing amyloid precursor ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2017
Entry Details
US Patent

TargetBeta-secretase 1(Human)
Amgen

US Patent
LigandChemical structure of BindingDB Monomer ID 214996BDBM214996(US9296734, 189)
Affinity DataIC50: 3nMpH: 4.2Assay Description:The assay buffer used in this screen is 0.05 M acetate, pH 4.2, 10% DMSO final, 100 uM genapol (which is a nonionic detergent, below its Critical Mic...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2017
Entry Details
US Patent

TargetBeta-secretase 1(Human)
Amgen

US Patent
LigandChemical structure of BindingDB Monomer ID 215016BDBM215016(US9296734, 208)
Affinity DataIC50: 3nMT: 2°CAssay Description:The cell-based assay measures inhibition or reduction of Aβ40 in conditioned medium of test compound treated cells expressing amyloid precursor ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2017
Entry Details
US Patent

TargetBeta-secretase 1(Human)
Amgen

US Patent
LigandChemical structure of BindingDB Monomer ID 214996BDBM214996(US9296734, 189)
Affinity DataIC50: 3nMT: 2°CAssay Description:The cell-based assay measures inhibition or reduction of Aβ40 in conditioned medium of test compound treated cells expressing amyloid precursor ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2017
Entry Details
US Patent

TargetBeta-secretase 1(Human)
Amgen

US Patent
LigandChemical structure of BindingDB Monomer ID 215011BDBM215011(US9296734, 204)
Affinity DataIC50: 3nMT: 2°CAssay Description:The cell-based assay measures inhibition or reduction of Aβ40 in conditioned medium of test compound treated cells expressing amyloid precursor ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2017
Entry Details
US Patent

TargetBeta-secretase 1(Human)
Amgen

US Patent
LigandChemical structure of BindingDB Monomer ID 214839BDBM214839(US9296734, 39)
Affinity DataIC50: 3.20nMT: 2°CAssay Description:The cell-based assay measures inhibition or reduction of Aβ40 in conditioned medium of test compound treated cells expressing amyloid precursor ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2017
Entry Details
US Patent

TargetBeta-secretase 1(Human)
Amgen

US Patent
LigandChemical structure of BindingDB Monomer ID 214966BDBM214966(US9296734, 160)
Affinity DataIC50: 3.5nMpH: 4.2Assay Description:The assay buffer used in this screen is 0.05 M acetate, pH 4.2, 10% DMSO final, 100 uM genapol (which is a nonionic detergent, below its Critical Mic...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2017
Entry Details
US Patent

TargetBeta-secretase 1(Human)
Amgen

US Patent
LigandChemical structure of BindingDB Monomer ID 214961BDBM214961(US9296734, 155)
Affinity DataIC50: 3.67nMT: 2°CAssay Description:The cell-based assay measures inhibition or reduction of Aβ40 in conditioned medium of test compound treated cells expressing amyloid precursor ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2017
Entry Details
US Patent

TargetBeta-secretase 1(Human)
Amgen

US Patent
LigandChemical structure of BindingDB Monomer ID 214881BDBM214881(US9296734, 82)
Affinity DataIC50: 4.5nMT: 2°CAssay Description:The cell-based assay measures inhibition or reduction of Aβ40 in conditioned medium of test compound treated cells expressing amyloid precursor ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2017
Entry Details
US Patent

TargetBeta-secretase 1(Human)
Amgen

US Patent
LigandChemical structure of BindingDB Monomer ID 214872BDBM214872(US9296734, 73)
Affinity DataIC50: 4.70nMpH: 4.2Assay Description:The assay buffer used in this screen is 0.05 M acetate, pH 4.2, 10% DMSO final, 100 uM genapol (which is a nonionic detergent, below its Critical Mic...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2017
Entry Details
US Patent

TargetBeta-secretase 1(Human)
Amgen

US Patent
LigandChemical structure of BindingDB Monomer ID 214883BDBM214883(US9296734, 84)
Affinity DataIC50: 4.80nMT: 2°CAssay Description:The cell-based assay measures inhibition or reduction of Aβ40 in conditioned medium of test compound treated cells expressing amyloid precursor ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2017
Entry Details
US Patent

TargetBeta-secretase 1(Human)
Amgen

US Patent
LigandChemical structure of BindingDB Monomer ID 214826BDBM214826(US9296734, 26 | US9296734, 60)
Affinity DataIC50: 4.90nMT: 2°CAssay Description:The cell-based assay measures inhibition or reduction of Aβ40 in conditioned medium of test compound treated cells expressing amyloid precursor ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2017
Entry Details
US Patent

TargetBeta-secretase 1(Human)
Amgen

US Patent
LigandChemical structure of BindingDB Monomer ID 214835BDBM214835(US9296734, 35)
Affinity DataIC50: 5.10nMT: 2°CAssay Description:The cell-based assay measures inhibition or reduction of Aβ40 in conditioned medium of test compound treated cells expressing amyloid precursor ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2017
Entry Details
US Patent

TargetBeta-secretase 1(Human)
Amgen

US Patent
LigandChemical structure of BindingDB Monomer ID 214971BDBM214971(US9296734, 164)
Affinity DataIC50: 5.20nMT: 2°CAssay Description:The cell-based assay measures inhibition or reduction of Aβ40 in conditioned medium of test compound treated cells expressing amyloid precursor ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2017
Entry Details
US Patent

TargetBeta-secretase 1(Human)
Amgen

US Patent
LigandChemical structure of BindingDB Monomer ID 214974BDBM214974(US9296734, 167)
Affinity DataIC50: 5.70nMT: 2°CAssay Description:The cell-based assay measures inhibition or reduction of Aβ40 in conditioned medium of test compound treated cells expressing amyloid precursor ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2017
Entry Details
US Patent

TargetBeta-secretase 1(Human)
Amgen

US Patent
LigandChemical structure of BindingDB Monomer ID 215047BDBM215047(US9296734, 238)
Affinity DataIC50: 6nMT: 2°CAssay Description:The cell-based assay measures inhibition or reduction of Aβ40 in conditioned medium of test compound treated cells expressing amyloid precursor ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2017
Entry Details
US Patent

TargetBeta-secretase 1(Human)
Amgen

US Patent
LigandChemical structure of BindingDB Monomer ID 214995BDBM214995(US9296734, 188)
Affinity DataIC50: 6nMpH: 4.2Assay Description:The assay buffer used in this screen is 0.05 M acetate, pH 4.2, 10% DMSO final, 100 uM genapol (which is a nonionic detergent, below its Critical Mic...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2017
Entry Details
US Patent

TargetBeta-secretase 1(Human)
Amgen

US Patent
LigandChemical structure of BindingDB Monomer ID 215011BDBM215011(US9296734, 204)
Affinity DataIC50: 6nMpH: 4.2Assay Description:The assay buffer used in this screen is 0.05 M acetate, pH 4.2, 10% DMSO final, 100 uM genapol (which is a nonionic detergent, below its Critical Mic...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2017
Entry Details
US Patent

TargetBeta-secretase 1(Human)
Amgen

US Patent
LigandChemical structure of BindingDB Monomer ID 214975BDBM214975(US9296734, 168)
Affinity DataIC50: 6.10nMT: 2°CAssay Description:The cell-based assay measures inhibition or reduction of Aβ40 in conditioned medium of test compound treated cells expressing amyloid precursor ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2017
Entry Details
US Patent

TargetBeta-secretase 1(Human)
Amgen

US Patent
LigandChemical structure of BindingDB Monomer ID 214982BDBM214982(US9296734, 175)
Affinity DataIC50: 6.60nMT: 2°CAssay Description:The cell-based assay measures inhibition or reduction of Aβ40 in conditioned medium of test compound treated cells expressing amyloid precursor ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2017
Entry Details
US Patent

TargetBeta-secretase 1(Human)
Amgen

US Patent
LigandChemical structure of BindingDB Monomer ID 214973BDBM214973(US9296734, 166)
Affinity DataIC50: 6.80nMT: 2°CAssay Description:The cell-based assay measures inhibition or reduction of Aβ40 in conditioned medium of test compound treated cells expressing amyloid precursor ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2017
Entry Details
US Patent

TargetBeta-secretase 1(Human)
Amgen

US Patent
LigandChemical structure of BindingDB Monomer ID 215003BDBM215003(US9296734, 196)
Affinity DataIC50: 7nMT: 2°CAssay Description:The cell-based assay measures inhibition or reduction of Aβ40 in conditioned medium of test compound treated cells expressing amyloid precursor ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2017
Entry Details
US Patent

TargetBeta-secretase 1(Human)
Amgen

US Patent
LigandChemical structure of BindingDB Monomer ID 215032BDBM215032(US9296734, 224)
Affinity DataIC50: 7nMT: 2°CAssay Description:The cell-based assay measures inhibition or reduction of Aβ40 in conditioned medium of test compound treated cells expressing amyloid precursor ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2017
Entry Details
US Patent

TargetBeta-secretase 1(Human)
Amgen

US Patent
LigandChemical structure of BindingDB Monomer ID 215047BDBM215047(US9296734, 238)
Affinity DataIC50: 8nMpH: 4.2Assay Description:The assay buffer used in this screen is 0.05 M acetate, pH 4.2, 10% DMSO final, 100 uM genapol (which is a nonionic detergent, below its Critical Mic...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2017
Entry Details
US Patent

TargetBeta-secretase 1(Human)
Amgen

US Patent
LigandChemical structure of BindingDB Monomer ID 215022BDBM215022(US9296734, 214)
Affinity DataIC50: 8nMpH: 4.2Assay Description:The assay buffer used in this screen is 0.05 M acetate, pH 4.2, 10% DMSO final, 100 uM genapol (which is a nonionic detergent, below its Critical Mic...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2017
Entry Details
US Patent

TargetBeta-secretase 1(Human)
Amgen

US Patent
LigandChemical structure of BindingDB Monomer ID 214803BDBM214803(US9296734, 4)
Affinity DataIC50: 8nMpH: 4.2Assay Description:The assay buffer used in this screen is 0.05 M acetate, pH 4.2, 10% DMSO final, 100 uM genapol (which is a nonionic detergent, below its Critical Mic...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2017
Entry Details
US Patent

TargetBeta-secretase 1(Human)
Amgen

US Patent
LigandChemical structure of BindingDB Monomer ID 214886BDBM214886(US9296734, 87)
Affinity DataIC50: 8.40nMT: 2°CAssay Description:The cell-based assay measures inhibition or reduction of Aβ40 in conditioned medium of test compound treated cells expressing amyloid precursor ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2017
Entry Details
US Patent

TargetBeta-secretase 1(Human)
Amgen

US Patent
LigandChemical structure of BindingDB Monomer ID 214891BDBM214891(US9296734, 169)
Affinity DataIC50: 8.90nMT: 2°CAssay Description:The cell-based assay measures inhibition or reduction of Aβ40 in conditioned medium of test compound treated cells expressing amyloid precursor ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2017
Entry Details
US Patent

TargetBeta-secretase 1(Human)
Amgen

US Patent
LigandChemical structure of BindingDB Monomer ID 214828BDBM214828(US9296734, 28)
Affinity DataIC50: 9.30nMT: 2°CAssay Description:The cell-based assay measures inhibition or reduction of Aβ40 in conditioned medium of test compound treated cells expressing amyloid precursor ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2017
Entry Details
US Patent

TargetBeta-secretase 1(Human)
Amgen

US Patent
LigandChemical structure of BindingDB Monomer ID 214977BDBM214977(US9296734, 170)
Affinity DataIC50: 9.5nMpH: 4.2Assay Description:The assay buffer used in this screen is 0.05 M acetate, pH 4.2, 10% DMSO final, 100 uM genapol (which is a nonionic detergent, below its Critical Mic...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2017
Entry Details
US Patent

TargetBeta-secretase 1(Human)
Amgen

US Patent
LigandChemical structure of BindingDB Monomer ID 214960BDBM214960(US9296734, 154)
Affinity DataIC50: 9.60nMT: 2°CAssay Description:The cell-based assay measures inhibition or reduction of Aβ40 in conditioned medium of test compound treated cells expressing amyloid precursor ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2017
Entry Details
US Patent

TargetBeta-secretase 1(Human)
Amgen

US Patent
LigandChemical structure of BindingDB Monomer ID 214972BDBM214972(US9296734, 165)
Affinity DataIC50: 9.80nMT: 2°CAssay Description:The cell-based assay measures inhibition or reduction of Aβ40 in conditioned medium of test compound treated cells expressing amyloid precursor ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2017
Entry Details
US Patent

TargetBeta-secretase 1(Human)
Amgen

US Patent
LigandChemical structure of BindingDB Monomer ID 214887BDBM214887(US9296734, 88)
Affinity DataIC50: 10nMT: 2°CAssay Description:The cell-based assay measures inhibition or reduction of Aβ40 in conditioned medium of test compound treated cells expressing amyloid precursor ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2017
Entry Details
US Patent

TargetBeta-secretase 1(Human)
Amgen

US Patent
LigandChemical structure of BindingDB Monomer ID 214999BDBM214999(US9296734, 192)
Affinity DataIC50: 10nMpH: 4.2Assay Description:The assay buffer used in this screen is 0.05 M acetate, pH 4.2, 10% DMSO final, 100 uM genapol (which is a nonionic detergent, below its Critical Mic...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2017
Entry Details
US Patent

TargetBeta-secretase 1(Human)
Amgen

US Patent
LigandChemical structure of BindingDB Monomer ID 215021BDBM215021(US9296734, 213)
Affinity DataIC50: 10nMpH: 4.2Assay Description:The assay buffer used in this screen is 0.05 M acetate, pH 4.2, 10% DMSO final, 100 uM genapol (which is a nonionic detergent, below its Critical Mic...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2017
Entry Details
US Patent

TargetBeta-secretase 1(Human)
Amgen

US Patent
LigandChemical structure of BindingDB Monomer ID 214851BDBM214851(US9296734, 52)
Affinity DataIC50: 10nMpH: 4.2Assay Description:The assay buffer used in this screen is 0.05 M acetate, pH 4.2, 10% DMSO final, 100 uM genapol (which is a nonionic detergent, below its Critical Mic...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2017
Entry Details
US Patent

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