Compile Data Set for Download or QSAR
Report error Found 698 Enz. Inhib. hit(s) with all data for entry = 7818
TargetBromodomain-containing protein 4 [352-457](Human)
Abbvie

US Patent
LigandChemical structure of BindingDB Monomer ID 220432BDBM220432(US9296741, 21)
Affinity DataKi:  0.25nM ΔG°:  -54.8kJ/molepH: 6.0 T: 2°CAssay Description:A time-resolved fluorescence resonance energy transfer (TR-FRET) assay was used to determine the affinities of compounds of the Examples listed in Ta...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2017
Entry Details
US Patent

TargetBromodomain-containing protein 4 [57-168](Human)
Abbvie

US Patent
LigandChemical structure of BindingDB Monomer ID 220432BDBM220432(US9296741, 21)
Affinity DataKi:  0.390nM ΔG°:  -53.7kJ/molepH: 6.0 T: 2°CAssay Description:A time-resolved fluorescence resonance energy transfer (TR-FRET) assay was used to determine the affinities of compounds of the Examples listed in Ta...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2017
Entry Details
US Patent

TargetBromodomain-containing protein 4 [352-457](Human)
Abbvie

US Patent
LigandChemical structure of BindingDB Monomer ID 220626BDBM220626(US9296741, 215)
Affinity DataKi:  0.460nM ΔG°:  -53.3kJ/molepH: 6.0 T: 2°CAssay Description:A time-resolved fluorescence resonance energy transfer (TR-FRET) assay was used to determine the affinities of compounds of the Examples listed in Ta...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2017
Entry Details
US Patent

TargetBromodomain-containing protein 4 [57-168](Human)
Abbvie

US Patent
LigandChemical structure of BindingDB Monomer ID 220518BDBM220518(US9296741, 107)
Affinity DataKi:  0.5nM ΔG°:  -53.1kJ/molepH: 6.0 T: 2°CAssay Description:A time-resolved fluorescence resonance energy transfer (TR-FRET) assay was used to determine the affinities of compounds of the Examples listed in Ta...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2017
Entry Details
US Patent

TargetBromodomain-containing protein 4 [352-457](Human)
Abbvie

US Patent
LigandChemical structure of BindingDB Monomer ID 220484BDBM220484(US9296741, 73)
Affinity DataKi:  0.5nM ΔG°:  -53.1kJ/molepH: 6.0 T: 2°CAssay Description:A time-resolved fluorescence resonance energy transfer (TR-FRET) assay was used to determine the affinities of compounds of the Examples listed in Ta...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2017
Entry Details
US Patent

TargetBromodomain-containing protein 4 [352-457](Human)
Abbvie

US Patent
LigandChemical structure of BindingDB Monomer ID 220452BDBM220452(US9296741, 41)
Affinity DataKi:  0.510nM ΔG°:  -53.0kJ/molepH: 6.0 T: 2°CAssay Description:A time-resolved fluorescence resonance energy transfer (TR-FRET) assay was used to determine the affinities of compounds of the Examples listed in Ta...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2017
Entry Details
US Patent

TargetBromodomain-containing protein 4 [57-168](Human)
Abbvie

US Patent
LigandChemical structure of BindingDB Monomer ID 220516BDBM220516(US9296741, 105)
Affinity DataKi:  0.520nM ΔG°:  -53.0kJ/molepH: 6.0 T: 2°CAssay Description:A time-resolved fluorescence resonance energy transfer (TR-FRET) assay was used to determine the affinities of compounds of the Examples listed in Ta...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2017
Entry Details
US Patent

TargetBromodomain-containing protein 4 [352-457](Human)
Abbvie

US Patent
LigandChemical structure of BindingDB Monomer ID 220679BDBM220679(US9296741, 268)
Affinity DataKi:  0.570nM ΔG°:  -52.8kJ/molepH: 6.0 T: 2°CAssay Description:A time-resolved fluorescence resonance energy transfer (TR-FRET) assay was used to determine the affinities of compounds of the Examples listed in Ta...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2017
Entry Details
US Patent

TargetBromodomain-containing protein 4 [57-168](Human)
Abbvie

US Patent
LigandChemical structure of BindingDB Monomer ID 220507BDBM220507(US9296741, 96)
Affinity DataKi:  0.630nM ΔG°:  -52.5kJ/molepH: 6.0 T: 2°CAssay Description:A time-resolved fluorescence resonance energy transfer (TR-FRET) assay was used to determine the affinities of compounds of the Examples listed in Ta...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2017
Entry Details
US Patent

TargetBromodomain-containing protein 4 [352-457](Human)
Abbvie

US Patent
LigandChemical structure of BindingDB Monomer ID 220495BDBM220495(US9296741, 84)
Affinity DataKi:  0.650nM ΔG°:  -52.4kJ/molepH: 6.0 T: 2°CAssay Description:A time-resolved fluorescence resonance energy transfer (TR-FRET) assay was used to determine the affinities of compounds of the Examples listed in Ta...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2017
Entry Details
US Patent

TargetBromodomain-containing protein 4 [352-457](Human)
Abbvie

US Patent
LigandChemical structure of BindingDB Monomer ID 220431BDBM220431(US9296741, 20 | US10633379, Compound Z)
Affinity DataKi:  0.680nM ΔG°:  -52.3kJ/molepH: 6.0 T: 2°CAssay Description:A time-resolved fluorescence resonance energy transfer (TR-FRET) assay was used to determine the affinities of compounds of the Examples listed in Ta...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2017
Entry Details
US Patent

TargetBromodomain-containing protein 4 [57-168](Human)
Abbvie

US Patent
LigandChemical structure of BindingDB Monomer ID 220614BDBM220614(US9296741, 203)
Affinity DataKi:  0.690nM ΔG°:  -52.3kJ/molepH: 6.0 T: 2°CAssay Description:A time-resolved fluorescence resonance energy transfer (TR-FRET) assay was used to determine the affinities of compounds of the Examples listed in Ta...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2017
Entry Details
US Patent

TargetBromodomain-containing protein 4 [57-168](Human)
Abbvie

US Patent
LigandChemical structure of BindingDB Monomer ID 220520BDBM220520(US9296741, 109)
Affinity DataKi:  0.720nM ΔG°:  -52.2kJ/molepH: 6.0 T: 2°CAssay Description:A time-resolved fluorescence resonance energy transfer (TR-FRET) assay was used to determine the affinities of compounds of the Examples listed in Ta...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2017
Entry Details
US Patent

TargetBromodomain-containing protein 4 [57-168](Human)
Abbvie

US Patent
LigandChemical structure of BindingDB Monomer ID 220477BDBM220477(US9296741, 66)
Affinity DataKi:  0.740nM ΔG°:  -52.1kJ/molepH: 6.0 T: 2°CAssay Description:A time-resolved fluorescence resonance energy transfer (TR-FRET) assay was used to determine the affinities of compounds of the Examples listed in Ta...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2017
Entry Details
US Patent

TargetBromodomain-containing protein 4 [57-168](Human)
Abbvie

US Patent
LigandChemical structure of BindingDB Monomer ID 220471BDBM220471(US9296741, 60)
Affinity DataKi:  0.75nM ΔG°:  -52.1kJ/molepH: 6.0 T: 2°CAssay Description:A time-resolved fluorescence resonance energy transfer (TR-FRET) assay was used to determine the affinities of compounds of the Examples listed in Ta...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2017
Entry Details
US Patent

TargetBromodomain-containing protein 4 [352-457](Human)
Abbvie

US Patent
LigandChemical structure of BindingDB Monomer ID 220434BDBM220434(US9296741, 23)
Affinity DataKi:  0.75nM ΔG°:  -52.1kJ/molepH: 6.0 T: 2°CAssay Description:A time-resolved fluorescence resonance energy transfer (TR-FRET) assay was used to determine the affinities of compounds of the Examples listed in Ta...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2017
Entry Details
US Patent

TargetBromodomain-containing protein 4 [352-457](Human)
Abbvie

US Patent
LigandChemical structure of BindingDB Monomer ID 220614BDBM220614(US9296741, 203)
Affinity DataKi:  0.75nM ΔG°:  -52.1kJ/molepH: 6.0 T: 2°CAssay Description:A time-resolved fluorescence resonance energy transfer (TR-FRET) assay was used to determine the affinities of compounds of the Examples listed in Ta...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2017
Entry Details
US Patent

TargetBromodomain-containing protein 4 [57-168](Human)
Abbvie

US Patent
LigandChemical structure of BindingDB Monomer ID 220679BDBM220679(US9296741, 268)
Affinity DataKi:  0.760nM ΔG°:  -52.0kJ/molepH: 6.0 T: 2°CAssay Description:A time-resolved fluorescence resonance energy transfer (TR-FRET) assay was used to determine the affinities of compounds of the Examples listed in Ta...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2017
Entry Details
US Patent

TargetBromodomain-containing protein 4 [352-457](Human)
Abbvie

US Patent
LigandChemical structure of BindingDB Monomer ID 220649BDBM220649(US9296741, 238)
Affinity DataKi:  0.780nM ΔG°:  -52.0kJ/molepH: 6.0 T: 2°CAssay Description:A time-resolved fluorescence resonance energy transfer (TR-FRET) assay was used to determine the affinities of compounds of the Examples listed in Ta...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2017
Entry Details
US Patent

TargetBromodomain-containing protein 4 [352-457](Human)
Abbvie

US Patent
LigandChemical structure of BindingDB Monomer ID 220608BDBM220608(US9296741, 197)
Affinity DataKi:  0.790nM ΔG°:  -52.0kJ/molepH: 6.0 T: 2°CAssay Description:A time-resolved fluorescence resonance energy transfer (TR-FRET) assay was used to determine the affinities of compounds of the Examples listed in Ta...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2017
Entry Details
US Patent

TargetBromodomain-containing protein 4 [57-168](Human)
Abbvie

US Patent
LigandChemical structure of BindingDB Monomer ID 220750BDBM220750(US9296741, 339)
Affinity DataKi:  0.800nM ΔG°:  -51.9kJ/molepH: 6.0 T: 2°CAssay Description:A time-resolved fluorescence resonance energy transfer (TR-FRET) assay was used to determine the affinities of compounds of the Examples listed in Ta...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2017
Entry Details
US Patent

TargetBromodomain-containing protein 4 [57-168](Human)
Abbvie

US Patent
LigandChemical structure of BindingDB Monomer ID 220482BDBM220482(US9296741, 71)
Affinity DataKi:  0.810nM ΔG°:  -51.9kJ/molepH: 6.0 T: 2°CAssay Description:A time-resolved fluorescence resonance energy transfer (TR-FRET) assay was used to determine the affinities of compounds of the Examples listed in Ta...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2017
Entry Details
US Patent

TargetBromodomain-containing protein 4 [57-168](Human)
Abbvie

US Patent
LigandChemical structure of BindingDB Monomer ID 220626BDBM220626(US9296741, 215)
Affinity DataKi:  0.830nM ΔG°:  -51.8kJ/molepH: 6.0 T: 2°CAssay Description:A time-resolved fluorescence resonance energy transfer (TR-FRET) assay was used to determine the affinities of compounds of the Examples listed in Ta...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2017
Entry Details
US Patent

TargetBromodomain-containing protein 4 [352-457](Human)
Abbvie

US Patent
LigandChemical structure of BindingDB Monomer ID 220660BDBM220660(US9296741, 249)
Affinity DataKi:  0.830nM ΔG°:  -51.8kJ/molepH: 6.0 T: 2°CAssay Description:A time-resolved fluorescence resonance energy transfer (TR-FRET) assay was used to determine the affinities of compounds of the Examples listed in Ta...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2017
Entry Details
US Patent

TargetBromodomain-containing protein 4 [57-168](Human)
Abbvie

US Patent
LigandChemical structure of BindingDB Monomer ID 220470BDBM220470(US9296741, 59)
Affinity DataKi:  0.840nM ΔG°:  -51.8kJ/molepH: 6.0 T: 2°CAssay Description:A time-resolved fluorescence resonance energy transfer (TR-FRET) assay was used to determine the affinities of compounds of the Examples listed in Ta...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2017
Entry Details
US Patent

TargetBromodomain-containing protein 4 [352-457](Human)
Abbvie

US Patent
LigandChemical structure of BindingDB Monomer ID 220580BDBM220580(US9296741, 169)
Affinity DataKi:  0.860nM ΔG°:  -51.7kJ/molepH: 6.0 T: 2°CAssay Description:A time-resolved fluorescence resonance energy transfer (TR-FRET) assay was used to determine the affinities of compounds of the Examples listed in Ta...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2017
Entry Details
US Patent

TargetBromodomain-containing protein 4 [57-168](Human)
Abbvie

US Patent
LigandChemical structure of BindingDB Monomer ID 220611BDBM220611(US9296741, 200)
Affinity DataKi:  0.860nM ΔG°:  -51.7kJ/molepH: 6.0 T: 2°CAssay Description:A time-resolved fluorescence resonance energy transfer (TR-FRET) assay was used to determine the affinities of compounds of the Examples listed in Ta...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2017
Entry Details
US Patent

TargetBromodomain-containing protein 4 [57-168](Human)
Abbvie

US Patent
LigandChemical structure of BindingDB Monomer ID 220749BDBM220749(US9296741, 338)
Affinity DataKi:  0.860nM ΔG°:  -51.7kJ/molepH: 6.0 T: 2°CAssay Description:A time-resolved fluorescence resonance energy transfer (TR-FRET) assay was used to determine the affinities of compounds of the Examples listed in Ta...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2017
Entry Details
US Patent

TargetBromodomain-containing protein 4 [352-457](Human)
Abbvie

US Patent
LigandChemical structure of BindingDB Monomer ID 220518BDBM220518(US9296741, 107)
Affinity DataKi:  0.870nM ΔG°:  -51.7kJ/molepH: 6.0 T: 2°CAssay Description:A time-resolved fluorescence resonance energy transfer (TR-FRET) assay was used to determine the affinities of compounds of the Examples listed in Ta...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2017
Entry Details
US Patent

TargetBromodomain-containing protein 4 [57-168](Human)
Abbvie

US Patent
LigandChemical structure of BindingDB Monomer ID 220468BDBM220468(US9296741, 57)
Affinity DataKi:  0.880nM ΔG°:  -51.7kJ/molepH: 6.0 T: 2°CAssay Description:A time-resolved fluorescence resonance energy transfer (TR-FRET) assay was used to determine the affinities of compounds of the Examples listed in Ta...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2017
Entry Details
US Patent

TargetBromodomain-containing protein 4 [57-168](Human)
Abbvie

US Patent
LigandChemical structure of BindingDB Monomer ID 220580BDBM220580(US9296741, 169)
Affinity DataKi:  0.880nM ΔG°:  -51.7kJ/molepH: 6.0 T: 2°CAssay Description:A time-resolved fluorescence resonance energy transfer (TR-FRET) assay was used to determine the affinities of compounds of the Examples listed in Ta...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2017
Entry Details
US Patent

TargetBromodomain-containing protein 4 [57-168](Human)
Abbvie

US Patent
LigandChemical structure of BindingDB Monomer ID 220484BDBM220484(US9296741, 73)
Affinity DataKi:  0.980nM ΔG°:  -51.4kJ/molepH: 6.0 T: 2°CAssay Description:A time-resolved fluorescence resonance energy transfer (TR-FRET) assay was used to determine the affinities of compounds of the Examples listed in Ta...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2017
Entry Details
US Patent

TargetBromodomain-containing protein 4 [352-457](Human)
Abbvie

US Patent
LigandChemical structure of BindingDB Monomer ID 220492BDBM220492(US9296741, 81)
Affinity DataKi:  0.990nM ΔG°:  -51.4kJ/molepH: 6.0 T: 2°CAssay Description:A time-resolved fluorescence resonance energy transfer (TR-FRET) assay was used to determine the affinities of compounds of the Examples listed in Ta...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2017
Entry Details
US Patent

TargetBromodomain-containing protein 4 [352-457](Human)
Abbvie

US Patent
LigandChemical structure of BindingDB Monomer ID 220433BDBM220433(US9296741, 22)
Affinity DataKi:  1nM ΔG°:  -51.4kJ/molepH: 6.0 T: 2°CAssay Description:A time-resolved fluorescence resonance energy transfer (TR-FRET) assay was used to determine the affinities of compounds of the Examples listed in Ta...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2017
Entry Details
US Patent

TargetBromodomain-containing protein 4 [57-168](Human)
Abbvie

US Patent
LigandChemical structure of BindingDB Monomer ID 220671BDBM220671(US9296741, 260)
Affinity DataKi:  1nM ΔG°:  -51.4kJ/molepH: 6.0 T: 2°CAssay Description:A time-resolved fluorescence resonance energy transfer (TR-FRET) assay was used to determine the affinities of compounds of the Examples listed in Ta...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2017
Entry Details
US Patent

TargetBromodomain-containing protein 4 [57-168](Human)
Abbvie

US Patent
LigandChemical structure of BindingDB Monomer ID 220649BDBM220649(US9296741, 238)
Affinity DataKi:  1.10nM ΔG°:  -51.1kJ/molepH: 6.0 T: 2°CAssay Description:A time-resolved fluorescence resonance energy transfer (TR-FRET) assay was used to determine the affinities of compounds of the Examples listed in Ta...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2017
Entry Details
US Patent

TargetBromodomain-containing protein 4 [352-457](Human)
Abbvie

US Patent
LigandChemical structure of BindingDB Monomer ID 220506BDBM220506(US9296741, 95)
Affinity DataKi:  1.10nM ΔG°:  -51.1kJ/molepH: 6.0 T: 2°CAssay Description:A time-resolved fluorescence resonance energy transfer (TR-FRET) assay was used to determine the affinities of compounds of the Examples listed in Ta...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2017
Entry Details
US Patent

TargetBromodomain-containing protein 4 [352-457](Human)
Abbvie

US Patent
LigandChemical structure of BindingDB Monomer ID 220558BDBM220558(US9296741, 147)
Affinity DataKi:  1.10nM ΔG°:  -51.1kJ/molepH: 6.0 T: 2°CAssay Description:A time-resolved fluorescence resonance energy transfer (TR-FRET) assay was used to determine the affinities of compounds of the Examples listed in Ta...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2017
Entry Details
US Patent

TargetBromodomain-containing protein 4 [352-457](Human)
Abbvie

US Patent
LigandChemical structure of BindingDB Monomer ID 220483BDBM220483(US9296741, 72)
Affinity DataKi:  1.10nM ΔG°:  -51.1kJ/molepH: 6.0 T: 2°CAssay Description:A time-resolved fluorescence resonance energy transfer (TR-FRET) assay was used to determine the affinities of compounds of the Examples listed in Ta...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2017
Entry Details
US Patent

TargetBromodomain-containing protein 4 [352-457](Human)
Abbvie

US Patent
LigandChemical structure of BindingDB Monomer ID 220507BDBM220507(US9296741, 96)
Affinity DataKi:  1.10nM ΔG°:  -51.1kJ/molepH: 6.0 T: 2°CAssay Description:A time-resolved fluorescence resonance energy transfer (TR-FRET) assay was used to determine the affinities of compounds of the Examples listed in Ta...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2017
Entry Details
US Patent

TargetBromodomain-containing protein 4 [57-168](Human)
Abbvie

US Patent
LigandChemical structure of BindingDB Monomer ID 220440BDBM220440(US9296741, 29)
Affinity DataKi:  1.10nM ΔG°:  -51.1kJ/molepH: 6.0 T: 2°CAssay Description:A time-resolved fluorescence resonance energy transfer (TR-FRET) assay was used to determine the affinities of compounds of the Examples listed in Ta...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2017
Entry Details
US Patent

TargetBromodomain-containing protein 4 [352-457](Human)
Abbvie

US Patent
LigandChemical structure of BindingDB Monomer ID 220611BDBM220611(US9296741, 200)
Affinity DataKi:  1.10nM ΔG°:  -51.1kJ/molepH: 6.0 T: 2°CAssay Description:A time-resolved fluorescence resonance energy transfer (TR-FRET) assay was used to determine the affinities of compounds of the Examples listed in Ta...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2017
Entry Details
US Patent
PDB3D3D Structure (crystal)
TargetBromodomain-containing protein 4 [352-457](Human)
Abbvie

US Patent
LigandChemical structure of BindingDB Monomer ID 220671BDBM220671(US9296741, 260)
Affinity DataKi:  1.20nM ΔG°:  -50.9kJ/molepH: 6.0 T: 2°CAssay Description:A time-resolved fluorescence resonance energy transfer (TR-FRET) assay was used to determine the affinities of compounds of the Examples listed in Ta...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2017
Entry Details
US Patent

TargetBromodomain-containing protein 4 [352-457](Human)
Abbvie

US Patent
LigandChemical structure of BindingDB Monomer ID 220735BDBM220735(US9296741, 324)
Affinity DataKi:  1.20nM ΔG°:  -50.9kJ/molepH: 6.0 T: 2°CAssay Description:A time-resolved fluorescence resonance energy transfer (TR-FRET) assay was used to determine the affinities of compounds of the Examples listed in Ta...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2017
Entry Details
US Patent

TargetBromodomain-containing protein 4 [57-168](Human)
Abbvie

US Patent
LigandChemical structure of BindingDB Monomer ID 220684BDBM220684(US9296741, 273)
Affinity DataKi:  1.20nM ΔG°:  -50.9kJ/molepH: 6.0 T: 2°CAssay Description:A time-resolved fluorescence resonance energy transfer (TR-FRET) assay was used to determine the affinities of compounds of the Examples listed in Ta...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2017
Entry Details
US Patent

TargetBromodomain-containing protein 4 [352-457](Human)
Abbvie

US Patent
LigandChemical structure of BindingDB Monomer ID 220664BDBM220664(US9296741, 253 | US10633379, Compound Y)
Affinity DataKi:  1.20nM ΔG°:  -50.9kJ/molepH: 6.0 T: 2°CAssay Description:A time-resolved fluorescence resonance energy transfer (TR-FRET) assay was used to determine the affinities of compounds of the Examples listed in Ta...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2017
Entry Details
US Patent
PDB3D3D Structure (crystal)
TargetBromodomain-containing protein 4 [57-168](Human)
Abbvie

US Patent
LigandChemical structure of BindingDB Monomer ID 220512BDBM220512(US9296741, 101)
Affinity DataKi:  1.20nM ΔG°:  -50.9kJ/molepH: 6.0 T: 2°CAssay Description:A time-resolved fluorescence resonance energy transfer (TR-FRET) assay was used to determine the affinities of compounds of the Examples listed in Ta...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2017
Entry Details
US Patent

TargetBromodomain-containing protein 4 [352-457](Human)
Abbvie

US Patent
LigandChemical structure of BindingDB Monomer ID 220454BDBM220454(US9296741, 43)
Affinity DataKi:  1.20nM ΔG°:  -50.9kJ/molepH: 6.0 T: 2°CAssay Description:A time-resolved fluorescence resonance energy transfer (TR-FRET) assay was used to determine the affinities of compounds of the Examples listed in Ta...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2017
Entry Details
US Patent

TargetBromodomain-containing protein 4 [57-168](Human)
Abbvie

US Patent
LigandChemical structure of BindingDB Monomer ID 220434BDBM220434(US9296741, 23)
Affinity DataKi:  1.20nM ΔG°:  -50.9kJ/molepH: 6.0 T: 2°CAssay Description:A time-resolved fluorescence resonance energy transfer (TR-FRET) assay was used to determine the affinities of compounds of the Examples listed in Ta...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2017
Entry Details
US Patent

TargetBromodomain-containing protein 4 [352-457](Human)
Abbvie

US Patent
LigandChemical structure of BindingDB Monomer ID 220482BDBM220482(US9296741, 71)
Affinity DataKi:  1.20nM ΔG°:  -50.9kJ/molepH: 6.0 T: 2°CAssay Description:A time-resolved fluorescence resonance energy transfer (TR-FRET) assay was used to determine the affinities of compounds of the Examples listed in Ta...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2017
Entry Details
US Patent

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