Compile Data Set for Download or QSAR
Report error Found 135 Enz. Inhib. hit(s) with all data for entry = 7907
TargetIsoform D of Beta-secretase 1 (BACE-I-432)(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 223358BDBM223358(US9315520, Comparator 7 | US9605007, Comparator 7 ...)
Affinity DataIC50: 1nMpH: 4.5 T: 2°CAssay Description:The substrate is Biotin-GLTNIKTEEISEISY^EVEFR-C[Oregon Green]KK-OH. The BACE1 enzyme is affinity purified material from conditioned media of CHO-K1 c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/1/2017
Entry Details
US Patent

TargetIsoform D of Beta-secretase 1 (BACE-I-432)(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 223381BDBM223381(US9315520, 96 | US9605007, Example 96 | US9744173,...)
Affinity DataIC50: 2nMpH: 4.5 T: 2°CAssay Description:The substrate is Biotin-GLTNIKTEEISEISY^EVEFR-C[Oregon Green]KK-OH. The BACE1 enzyme is affinity purified material from conditioned media of CHO-K1 c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/1/2017
Entry Details
US Patent

TargetIsoform D of Beta-secretase 1 (BACE-I-432)(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 223398BDBM223398(US9315520, Comparator 2 | US9315520, Comparator 3 ...)
Affinity DataIC50: 3nMpH: 4.5 T: 2°CAssay Description:The substrate is Biotin-GLTNIKTEEISEISY^EVEFR-C[Oregon Green]KK-OH. The BACE1 enzyme is affinity purified material from conditioned media of CHO-K1 c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/1/2017
Entry Details
US Patent

TargetIsoform D of Beta-secretase 1 (BACE-I-432)(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 223412BDBM223412(US9315520, 6)
Affinity DataIC50: 4nMpH: 4.5 T: 2°CAssay Description:The substrate is Biotin-GLTNIKTEEISEISY^EVEFR-C[Oregon Green]KK-OH. The BACE1 enzyme is affinity purified material from conditioned media of CHO-K1 c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/1/2017
Entry Details
US Patent

TargetIsoform D of Beta-secretase 1 (BACE-I-432)(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 223413BDBM223413(US9315520, Comparator 6 | US9605007, Comparator 6 ...)
Affinity DataIC50: 6nMpH: 4.5 T: 2°CAssay Description:The substrate is Biotin-GLTNIKTEEISEISY^EVEFR-C[Oregon Green]KK-OH. The BACE1 enzyme is affinity purified material from conditioned media of CHO-K1 c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/1/2017
Entry Details
US Patent

TargetIsoform D of Beta-secretase 1 (BACE-I-432)(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 223409BDBM223409(US9315520, 3)
Affinity DataIC50: 7nMpH: 4.5 T: 2°CAssay Description:The substrate is Biotin-GLTNIKTEEISEISY^EVEFR-C[Oregon Green]KK-OH. The BACE1 enzyme is affinity purified material from conditioned media of CHO-K1 c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/1/2017
Entry Details
US Patent

TargetIsoform D of Beta-secretase 1 (BACE-I-432)(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 223406BDBM223406(US9315520, Comparator 4 | US9605007, Comparator 4)
Affinity DataIC50: 9nMpH: 4.5 T: 2°CAssay Description:The substrate is Biotin-GLTNIKTEEISEISY^EVEFR-C[Oregon Green]KK-OH. The BACE1 enzyme is affinity purified material from conditioned media of CHO-K1 c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/1/2017
Entry Details
US Patent

TargetIsoform D of Beta-secretase 1 (BACE-I-432)(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 223415BDBM223415(US9315520, 8)
Affinity DataIC50: 11nMpH: 4.5 T: 2°CAssay Description:The substrate is Biotin-GLTNIKTEEISEISY^EVEFR-C[Oregon Green]KK-OH. The BACE1 enzyme is affinity purified material from conditioned media of CHO-K1 c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/1/2017
Entry Details
US Patent

TargetIsoform D of Beta-secretase 1 (BACE-I-432)(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 223387BDBM223387(US9315520, 102 | US9605007, Example 102 | US974417...)
Affinity DataIC50: 12nMpH: 4.5 T: 2°CAssay Description:The substrate is Biotin-GLTNIKTEEISEISY^EVEFR-C[Oregon Green]KK-OH. The BACE1 enzyme is affinity purified material from conditioned media of CHO-K1 c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/1/2017
Entry Details
US Patent

TargetIsoform D of Beta-secretase 1 (BACE-I-432)(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 223335BDBM223335(US9315520, 22 | US9605007, Example 22 | US9744173,...)
Affinity DataIC50: 13nMpH: 4.5 T: 2°CAssay Description:The substrate is Biotin-GLTNIKTEEISEISY^EVEFR-C[Oregon Green]KK-OH. The BACE1 enzyme is affinity purified material from conditioned media of CHO-K1 c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/1/2017
Entry Details
US Patent

TargetIsoform D of Beta-secretase 1 (BACE-I-432)(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 223374BDBM223374(US9315520, 89 | US9605007, Example 89 | US9744173,...)
Affinity DataIC50: 17nMpH: 4.5 T: 2°CAssay Description:The substrate is Biotin-GLTNIKTEEISEISY^EVEFR-C[Oregon Green]KK-OH. The BACE1 enzyme is affinity purified material from conditioned media of CHO-K1 c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/1/2017
Entry Details
US Patent

TargetIsoform D of Beta-secretase 1 (BACE-I-432)(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 223379BDBM223379(US9315520, 94 | US9605007, Example 94 | US9744173,...)
Affinity DataIC50: 18nMpH: 4.5 T: 2°CAssay Description:The substrate is Biotin-GLTNIKTEEISEISY^EVEFR-C[Oregon Green]KK-OH. The BACE1 enzyme is affinity purified material from conditioned media of CHO-K1 c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/1/2017
Entry Details
US Patent

TargetIsoform D of Beta-secretase 1 (BACE-I-432)(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 223410BDBM223410(US9315520, 4)
Affinity DataIC50: 19nMpH: 4.5 T: 2°CAssay Description:The substrate is Biotin-GLTNIKTEEISEISY^EVEFR-C[Oregon Green]KK-OH. The BACE1 enzyme is affinity purified material from conditioned media of CHO-K1 c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/1/2017
Entry Details
US Patent

TargetIsoform D of Beta-secretase 1 (BACE-I-432)(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 223414BDBM223414(US9315520, 7-HCl)
Affinity DataIC50: 19nMpH: 4.5 T: 2°CAssay Description:The substrate is Biotin-GLTNIKTEEISEISY^EVEFR-C[Oregon Green]KK-OH. The BACE1 enzyme is affinity purified material from conditioned media of CHO-K1 c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/1/2017
Entry Details
US Patent

TargetIsoform D of Beta-secretase 1 (BACE-I-432)(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 223411BDBM223411(US9315520, 5)
Affinity DataIC50: 22nMpH: 4.5 T: 2°CAssay Description:The substrate is Biotin-GLTNIKTEEISEISY^EVEFR-C[Oregon Green]KK-OH. The BACE1 enzyme is affinity purified material from conditioned media of CHO-K1 c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/1/2017
Entry Details
US Patent

TargetIsoform D of Beta-secretase 1 (BACE-I-432)(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 223400BDBM223400(US9315520, Example 45 | US9315520, 45 | US9605007,...)
Affinity DataIC50: 23nMpH: 4.5 T: 2°CAssay Description:The substrate is Biotin-GLTNIKTEEISEISY^EVEFR-C[Oregon Green]KK-OH. The BACE1 enzyme is affinity purified material from conditioned media of CHO-K1 c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/1/2017
Entry Details
US Patent

TargetIsoform D of Beta-secretase 1 (BACE-I-432)(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 223384BDBM223384(US9315520, 99 | US9605007, Example 99 | US9744173,...)
Affinity DataIC50: 25nMpH: 4.5 T: 2°CAssay Description:The substrate is Biotin-GLTNIKTEEISEISY^EVEFR-C[Oregon Green]KK-OH. The BACE1 enzyme is affinity purified material from conditioned media of CHO-K1 c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/1/2017
Entry Details
US Patent

TargetCytochrome P450 2D6(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 223358BDBM223358(US9315520, Comparator 7 | US9605007, Comparator 7 ...)
Affinity DataIC50: 30nMAssay Description:CYP2D6 inhibition was obtained by measuring inhibition of 5 uM Dextromethorphan in pooled HLM (HL-MIX-102).More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/1/2017
Entry Details
US Patent

TargetCytochrome P450 2D6(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 223413BDBM223413(US9315520, Comparator 6 | US9605007, Comparator 6 ...)
Affinity DataIC50: 30nMAssay Description:CYP2D6 inhibition was obtained by measuring inhibition of 5 uM Dextromethorphan in pooled HLM (HL-MIX-102).More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/1/2017
Entry Details
US Patent

TargetCytochrome P450 2D6(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 223398BDBM223398(US9315520, Comparator 2 | US9315520, Comparator 3 ...)
Affinity DataIC50: 30nMAssay Description:CYP2D6 inhibition was obtained by measuring inhibition of 5 uM Dextromethorphan in pooled HLM (HL-MIX-102).More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/1/2017
Entry Details
US Patent

TargetCytochrome P450 2D6(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 223398BDBM223398(US9315520, Comparator 2 | US9315520, Comparator 3 ...)
Affinity DataIC50: 30nMAssay Description:CYP2D6 inhibition was obtained by measuring inhibition of 5 uM Dextromethorphan in pooled HLM (HL-MIX-102).More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/1/2017
Entry Details
US Patent

TargetIsoform D of Beta-secretase 1 (BACE-I-432)(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 223407BDBM223407(US9315520, 1-HCl)
Affinity DataIC50: 31nMpH: 4.5 T: 2°CAssay Description:The substrate is Biotin-GLTNIKTEEISEISY^EVEFR-C[Oregon Green]KK-OH. The BACE1 enzyme is affinity purified material from conditioned media of CHO-K1 c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/1/2017
Entry Details
US Patent

TargetIsoform D of Beta-secretase 1 (BACE-I-432)(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 223383BDBM223383(US9315520, 98 | US9605007, Example 98 | US9744173,...)
Affinity DataIC50: 33nMpH: 4.5 T: 2°CAssay Description:The substrate is Biotin-GLTNIKTEEISEISY^EVEFR-C[Oregon Green]KK-OH. The BACE1 enzyme is affinity purified material from conditioned media of CHO-K1 c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/1/2017
Entry Details
US Patent

TargetIsoform D of Beta-secretase 1 (BACE-I-432)(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 223396BDBM223396(US9315520, Example 7 | US9315520, 7 | US9605007, E...)
Affinity DataIC50: 33nMpH: 4.5 T: 2°CAssay Description:The substrate is Biotin-GLTNIKTEEISEISY^EVEFR-C[Oregon Green]KK-OH. The BACE1 enzyme is affinity purified material from conditioned media of CHO-K1 c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/1/2017
Entry Details
US Patent

TargetIsoform D of Beta-secretase 1 (BACE-I-432)(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 223395BDBM223395(US9315520, Example 1 | US9315520, Comparator 1 | U...)
Affinity DataIC50: 41nMpH: 4.5 T: 2°CAssay Description:The substrate is Biotin-GLTNIKTEEISEISY^EVEFR-C[Oregon Green]KK-OH. The BACE1 enzyme is affinity purified material from conditioned media of CHO-K1 c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/1/2017
Entry Details
US Patent

TargetIsoform D of Beta-secretase 1 (BACE-I-432)(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 223398BDBM223398(US9315520, Comparator 2 | US9315520, Comparator 3 ...)
Affinity DataIC50: 43nMpH: 4.5 T: 2°CAssay Description:The substrate is Biotin-GLTNIKTEEISEISY^EVEFR-C[Oregon Green]KK-OH. The BACE1 enzyme is affinity purified material from conditioned media of CHO-K1 c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/1/2017
Entry Details
US Patent

TargetIsoform D of Beta-secretase 1 (BACE-I-432)(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 223330BDBM223330(US9315520, 17 | US9605007, Example 17 | US9744173,...)
Affinity DataIC50: 54nMpH: 4.5 T: 2°CAssay Description:The substrate is Biotin-GLTNIKTEEISEISY^EVEFR-C[Oregon Green]KK-OH. The BACE1 enzyme is affinity purified material from conditioned media of CHO-K1 c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/1/2017
Entry Details
US Patent

TargetIsoform D of Beta-secretase 1 (BACE-I-432)(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 223366BDBM223366(US9315520, 53 | US9605007, Example 53 | US9744173,...)
Affinity DataIC50: 65nMpH: 4.5 T: 2°CAssay Description:The substrate is Biotin-GLTNIKTEEISEISY^EVEFR-C[Oregon Green]KK-OH. The BACE1 enzyme is affinity purified material from conditioned media of CHO-K1 c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/1/2017
Entry Details
US Patent

TargetCytochrome P450 2D6(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 223406BDBM223406(US9315520, Comparator 4 | US9605007, Comparator 4)
Affinity DataIC50: 65nMAssay Description:CYP2D6 inhibition was obtained by measuring inhibition of 5 uM Dextromethorphan in pooled HLM (HL-MIX-102).More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/1/2017
Entry Details
US Patent

TargetIsoform D of Beta-secretase 1 (BACE-I-432)(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 223339BDBM223339(US9315520, 26 | US9605007, Example 26 | US9744173,...)
Affinity DataIC50: 68nMpH: 4.5 T: 2°CAssay Description:The substrate is Biotin-GLTNIKTEEISEISY^EVEFR-C[Oregon Green]KK-OH. The BACE1 enzyme is affinity purified material from conditioned media of CHO-K1 c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/1/2017
Entry Details
US Patent

TargetIsoform D of Beta-secretase 1 (BACE-I-432)(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 223395BDBM223395(US9315520, Example 1 | US9315520, Comparator 1 | U...)
Affinity DataIC50: 73nMpH: 4.5 T: 2°CAssay Description:The substrate is Biotin-GLTNIKTEEISEISY^EVEFR-C[Oregon Green]KK-OH. The BACE1 enzyme is affinity purified material from conditioned media of CHO-K1 c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/1/2017
Entry Details
US Patent

TargetIsoform D of Beta-secretase 1 (BACE-I-432)(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 223408BDBM223408(US9315520, Comparator 5)
Affinity DataIC50: 73nMpH: 4.5 T: 2°CAssay Description:The substrate is Biotin-GLTNIKTEEISEISY^EVEFR-C[Oregon Green]KK-OH. The BACE1 enzyme is affinity purified material from conditioned media of CHO-K1 c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/1/2017
Entry Details
US Patent

TargetIsoform D of Beta-secretase 1 (BACE-I-432)(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 223338BDBM223338(US9315520, 25 | US9605007, Example 25 | US9744173,...)
Affinity DataIC50: 74nMpH: 4.5 T: 2°CAssay Description:The substrate is Biotin-GLTNIKTEEISEISY^EVEFR-C[Oregon Green]KK-OH. The BACE1 enzyme is affinity purified material from conditioned media of CHO-K1 c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/1/2017
Entry Details
US Patent

TargetIsoform D of Beta-secretase 1 (BACE-I-432)(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 223380BDBM223380(US9315520, 95 | US9605007, Example 95 | US9744173,...)
Affinity DataIC50: 75nMpH: 4.5 T: 2°CAssay Description:The substrate is Biotin-GLTNIKTEEISEISY^EVEFR-C[Oregon Green]KK-OH. The BACE1 enzyme is affinity purified material from conditioned media of CHO-K1 c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/1/2017
Entry Details
US Patent

TargetIsoform D of Beta-secretase 1 (BACE-I-432)(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 223337BDBM223337(US9315520, 24 | US9605007, Example 24 | US9744173,...)
Affinity DataIC50: 81nMpH: 4.5 T: 2°CAssay Description:The substrate is Biotin-GLTNIKTEEISEISY^EVEFR-C[Oregon Green]KK-OH. The BACE1 enzyme is affinity purified material from conditioned media of CHO-K1 c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/1/2017
Entry Details
US Patent

TargetIsoform D of Beta-secretase 1 (BACE-I-432)(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 223377BDBM223377(US9315520, 92 | US9605007, Example 92)
Affinity DataIC50: 82nMpH: 4.5 T: 2°CAssay Description:The substrate is Biotin-GLTNIKTEEISEISY^EVEFR-C[Oregon Green]KK-OH. The BACE1 enzyme is affinity purified material from conditioned media of CHO-K1 c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/1/2017
Entry Details
US Patent

TargetIsoform D of Beta-secretase 1 (BACE-I-432)(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 223390BDBM223390(US9315520, 105 | US9605007, Example 105 | US974417...)
Affinity DataIC50: 85nMpH: 4.5 T: 2°CAssay Description:The substrate is Biotin-GLTNIKTEEISEISY^EVEFR-C[Oregon Green]KK-OH. The BACE1 enzyme is affinity purified material from conditioned media of CHO-K1 c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/1/2017
Entry Details
US Patent

TargetIsoform D of Beta-secretase 1 (BACE-I-432)(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 223326BDBM223326(US9315520, 13 | US9605007, Example 13 | US9744173,...)
Affinity DataIC50: 90nMpH: 4.5 T: 2°CAssay Description:The substrate is Biotin-GLTNIKTEEISEISY^EVEFR-C[Oregon Green]KK-OH. The BACE1 enzyme is affinity purified material from conditioned media of CHO-K1 c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/1/2017
Entry Details
US Patent

TargetIsoform D of Beta-secretase 1 (BACE-I-432)(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 223365BDBM223365(US9315520, 52 | US9605007, Example 52 | US9744173,...)
Affinity DataIC50: 91nMpH: 4.5 T: 2°CAssay Description:The substrate is Biotin-GLTNIKTEEISEISY^EVEFR-C[Oregon Green]KK-OH. The BACE1 enzyme is affinity purified material from conditioned media of CHO-K1 c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/1/2017
Entry Details
US Patent

TargetIsoform D of Beta-secretase 1 (BACE-I-432)(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 223393BDBM223393(US9315520, 108)
Affinity DataIC50: 94nMpH: 4.5 T: 2°CAssay Description:The substrate is Biotin-GLTNIKTEEISEISY^EVEFR-C[Oregon Green]KK-OH. The BACE1 enzyme is affinity purified material from conditioned media of CHO-K1 c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/1/2017
Entry Details
US Patent

TargetIsoform D of Beta-secretase 1 (BACE-I-432)(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 223364BDBM223364(US9315520, 51 | US9605007, Example 51 | US9744173,...)
Affinity DataIC50: 98nMpH: 4.5 T: 2°CAssay Description:The substrate is Biotin-GLTNIKTEEISEISY^EVEFR-C[Oregon Green]KK-OH. The BACE1 enzyme is affinity purified material from conditioned media of CHO-K1 c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/1/2017
Entry Details
US Patent

TargetIsoform D of Beta-secretase 1 (BACE-I-432)(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 223360BDBM223360(US9315520, 47 | US9605007, Example 47 | US9744173,...)
Affinity DataIC50: 101nMpH: 4.5 T: 2°CAssay Description:The substrate is Biotin-GLTNIKTEEISEISY^EVEFR-C[Oregon Green]KK-OH. The BACE1 enzyme is affinity purified material from conditioned media of CHO-K1 c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/1/2017
Entry Details
US Patent

TargetIsoform D of Beta-secretase 1 (BACE-I-432)(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 223362BDBM223362(US9315520, 49 | US9605007, Example 49 | US9744173,...)
Affinity DataIC50: 103nMpH: 4.5 T: 2°CAssay Description:The substrate is Biotin-GLTNIKTEEISEISY^EVEFR-C[Oregon Green]KK-OH. The BACE1 enzyme is affinity purified material from conditioned media of CHO-K1 c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/1/2017
Entry Details
US Patent

TargetIsoform D of Beta-secretase 1 (BACE-I-432)(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 223334BDBM223334(US9315520, 21 | US9605007, Example 21 | US9744173,...)
Affinity DataIC50: 106nMpH: 4.5 T: 2°CAssay Description:The substrate is Biotin-GLTNIKTEEISEISY^EVEFR-C[Oregon Green]KK-OH. The BACE1 enzyme is affinity purified material from conditioned media of CHO-K1 c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/1/2017
Entry Details
US Patent

TargetIsoform D of Beta-secretase 1 (BACE-I-432)(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 223333BDBM223333(US9315520, 20 | US9605007, Example 20 | US9744173,...)
Affinity DataIC50: 108nMpH: 4.5 T: 2°CAssay Description:The substrate is Biotin-GLTNIKTEEISEISY^EVEFR-C[Oregon Green]KK-OH. The BACE1 enzyme is affinity purified material from conditioned media of CHO-K1 c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/1/2017
Entry Details
US Patent

TargetIsoform D of Beta-secretase 1 (BACE-I-432)(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 223353BDBM223353(US9315520, 40 | US9605007, Example 40 | US9744173,...)
Affinity DataIC50: 134nMpH: 4.5 T: 2°CAssay Description:The substrate is Biotin-GLTNIKTEEISEISY^EVEFR-C[Oregon Green]KK-OH. The BACE1 enzyme is affinity purified material from conditioned media of CHO-K1 c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/1/2017
Entry Details
US Patent

TargetIsoform D of Beta-secretase 1 (BACE-I-432)(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 223328BDBM223328(US9315520, 15 | US9605007, Example 15 | US9744173,...)
Affinity DataIC50: 145nMpH: 4.5 T: 2°CAssay Description:The substrate is Biotin-GLTNIKTEEISEISY^EVEFR-C[Oregon Green]KK-OH. The BACE1 enzyme is affinity purified material from conditioned media of CHO-K1 c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/1/2017
Entry Details
US Patent

TargetIsoform D of Beta-secretase 1 (BACE-I-432)(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 223351BDBM223351(US9315520, 38 | US9605007, Example 38 | US9744173,...)
Affinity DataIC50: 145nMpH: 4.5 T: 2°CAssay Description:The substrate is Biotin-GLTNIKTEEISEISY^EVEFR-C[Oregon Green]KK-OH. The BACE1 enzyme is affinity purified material from conditioned media of CHO-K1 c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/1/2017
Entry Details
US Patent

TargetIsoform D of Beta-secretase 1 (BACE-I-432)(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 223331BDBM223331(US9315520, 18 | US9605007, Example 18 | US9744173,...)
Affinity DataIC50: 153nMpH: 4.5 T: 2°CAssay Description:The substrate is Biotin-GLTNIKTEEISEISY^EVEFR-C[Oregon Green]KK-OH. The BACE1 enzyme is affinity purified material from conditioned media of CHO-K1 c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/1/2017
Entry Details
US Patent

TargetIsoform D of Beta-secretase 1 (BACE-I-432)(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 223371BDBM223371(US9315520, 58 | US9605007, Example 58 | US9744173,...)
Affinity DataIC50: 161nMpH: 4.5 T: 2°CAssay Description:The substrate is Biotin-GLTNIKTEEISEISY^EVEFR-C[Oregon Green]KK-OH. The BACE1 enzyme is affinity purified material from conditioned media of CHO-K1 c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/1/2017
Entry Details
US Patent

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