Compile Data Set for Download or QSAR
Report error Found 228 Enz. Inhib. hit(s) with all data for entry = 8117
TargetTyrosine-protein kinase SYK(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 233627BDBM233627(US9353066, 1.80)
Affinity DataIC50: 1.30nMpH: 7.5 T: 2°CAssay Description:A recombinant GST-hSYK fusion protein was used to measure potency of compounds to inhibit human Syk activity. The recombinant human GST-SYK (Carna Bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2017
Entry Details
US Patent

TargetTyrosine-protein kinase SYK(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 233625BDBM233625(US9353066, 1.78)
Affinity DataIC50: 1.90nMpH: 7.5 T: 2°CAssay Description:A recombinant GST-hSYK fusion protein was used to measure potency of compounds to inhibit human Syk activity. The recombinant human GST-SYK (Carna Bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2017
Entry Details
US Patent

TargetTyrosine-protein kinase SYK(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 233769BDBM233769(US9353066, 4.8)
Affinity DataIC50: 2.20nMpH: 7.5 T: 2°CAssay Description:A recombinant GST-hSYK fusion protein was used to measure potency of compounds to inhibit human Syk activity. The recombinant human GST-SYK (Carna Bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2017
Entry Details
US Patent

TargetTyrosine-protein kinase SYK(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 233643BDBM233643(US9353066, 1.96)
Affinity DataIC50: 2.70nMpH: 7.5 T: 2°CAssay Description:A recombinant GST-hSYK fusion protein was used to measure potency of compounds to inhibit human Syk activity. The recombinant human GST-SYK (Carna Bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2017
Entry Details
US Patent

TargetTyrosine-protein kinase SYK(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 233645BDBM233645(US9353066, 1.98)
Affinity DataIC50: 2.80nMpH: 7.5 T: 2°CAssay Description:A recombinant GST-hSYK fusion protein was used to measure potency of compounds to inhibit human Syk activity. The recombinant human GST-SYK (Carna Bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2017
Entry Details
US Patent

TargetTyrosine-protein kinase SYK(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 233650BDBM233650(US9353066, 1.103)
Affinity DataIC50: 3.20nMpH: 7.5 T: 2°CAssay Description:A recombinant GST-hSYK fusion protein was used to measure potency of compounds to inhibit human Syk activity. The recombinant human GST-SYK (Carna Bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2017
Entry Details
US Patent

TargetTyrosine-protein kinase SYK(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 233574BDBM233574(US9353066, 1.27)
Affinity DataIC50: 3.30nMpH: 7.5 T: 2°CAssay Description:A recombinant GST-hSYK fusion protein was used to measure potency of compounds to inhibit human Syk activity. The recombinant human GST-SYK (Carna Bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2017
Entry Details
US Patent

TargetTyrosine-protein kinase SYK(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 233667BDBM233667(US9353066, 1.120)
Affinity DataIC50: 4.20nMpH: 7.5 T: 2°CAssay Description:A recombinant GST-hSYK fusion protein was used to measure potency of compounds to inhibit human Syk activity. The recombinant human GST-SYK (Carna Bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2017
Entry Details
US Patent

TargetTyrosine-protein kinase SYK(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 233626BDBM233626(US9353066, 1.79)
Affinity DataIC50: 4.60nMpH: 7.5 T: 2°CAssay Description:A recombinant GST-hSYK fusion protein was used to measure potency of compounds to inhibit human Syk activity. The recombinant human GST-SYK (Carna Bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2017
Entry Details
US Patent

TargetTyrosine-protein kinase SYK(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 233765BDBM233765(US9353066, 4.4)
Affinity DataIC50: 4.60nMpH: 7.5 T: 2°CAssay Description:A recombinant GST-hSYK fusion protein was used to measure potency of compounds to inhibit human Syk activity. The recombinant human GST-SYK (Carna Bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2017
Entry Details
US Patent

TargetTyrosine-protein kinase SYK(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 233649BDBM233649(US9353066, 1.102)
Affinity DataIC50: 4.80nMpH: 7.5 T: 2°CAssay Description:A recombinant GST-hSYK fusion protein was used to measure potency of compounds to inhibit human Syk activity. The recombinant human GST-SYK (Carna Bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2017
Entry Details
US Patent

TargetTyrosine-protein kinase SYK(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 233740BDBM233740(US9353066, 3.38)
Affinity DataIC50: 5.60nMpH: 7.5 T: 2°CAssay Description:A recombinant GST-hSYK fusion protein was used to measure potency of compounds to inhibit human Syk activity. The recombinant human GST-SYK (Carna Bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2017
Entry Details
US Patent

TargetTyrosine-protein kinase SYK(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 233646BDBM233646(US9353066, 1.99)
Affinity DataIC50: 5.60nMpH: 7.5 T: 2°CAssay Description:A recombinant GST-hSYK fusion protein was used to measure potency of compounds to inhibit human Syk activity. The recombinant human GST-SYK (Carna Bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2017
Entry Details
US Patent

TargetTyrosine-protein kinase SYK(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 233635BDBM233635(US9353066, 1.88)
Affinity DataIC50: 5.90nMpH: 7.5 T: 2°CAssay Description:A recombinant GST-hSYK fusion protein was used to measure potency of compounds to inhibit human Syk activity. The recombinant human GST-SYK (Carna Bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2017
Entry Details
US Patent

TargetTyrosine-protein kinase SYK(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 233687BDBM233687(US9353066, 1.141)
Affinity DataIC50: 6.20nMpH: 7.5 T: 2°CAssay Description:A recombinant GST-hSYK fusion protein was used to measure potency of compounds to inhibit human Syk activity. The recombinant human GST-SYK (Carna Bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2017
Entry Details
US Patent

TargetTyrosine-protein kinase SYK(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 233695BDBM233695(US9353066, 2.3)
Affinity DataIC50: 6.30nMpH: 7.5 T: 2°CAssay Description:A recombinant GST-hSYK fusion protein was used to measure potency of compounds to inhibit human Syk activity. The recombinant human GST-SYK (Carna Bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2017
Entry Details
US Patent

TargetTyrosine-protein kinase SYK(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 233686BDBM233686(US9353066, 1.140)
Affinity DataIC50: 6.40nMpH: 7.5 T: 2°CAssay Description:A recombinant GST-hSYK fusion protein was used to measure potency of compounds to inhibit human Syk activity. The recombinant human GST-SYK (Carna Bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2017
Entry Details
US Patent

TargetTyrosine-protein kinase SYK(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 233666BDBM233666(US9353066, 1.119)
Affinity DataIC50: 6.5nMpH: 7.5 T: 2°CAssay Description:A recombinant GST-hSYK fusion protein was used to measure potency of compounds to inhibit human Syk activity. The recombinant human GST-SYK (Carna Bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2017
Entry Details
US Patent

TargetTyrosine-protein kinase SYK(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 233659BDBM233659(US9353066, 1.112)
Affinity DataIC50: 6.60nMpH: 7.5 T: 2°CAssay Description:A recombinant GST-hSYK fusion protein was used to measure potency of compounds to inhibit human Syk activity. The recombinant human GST-SYK (Carna Bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2017
Entry Details
US Patent

TargetTyrosine-protein kinase SYK(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 233706BDBM233706(US9353066, 3.4)
Affinity DataIC50: 6.90nMpH: 7.5 T: 2°CAssay Description:A recombinant GST-hSYK fusion protein was used to measure potency of compounds to inhibit human Syk activity. The recombinant human GST-SYK (Carna Bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2017
Entry Details
US Patent

TargetTyrosine-protein kinase SYK(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 233631BDBM233631(US9353066, 1.84)
Affinity DataIC50: 7.10nMpH: 7.5 T: 2°CAssay Description:A recombinant GST-hSYK fusion protein was used to measure potency of compounds to inhibit human Syk activity. The recombinant human GST-SYK (Carna Bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2017
Entry Details
US Patent

TargetTyrosine-protein kinase SYK(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 233764BDBM233764(US9353066, 4.3)
Affinity DataIC50: 7.40nMpH: 7.5 T: 2°CAssay Description:A recombinant GST-hSYK fusion protein was used to measure potency of compounds to inhibit human Syk activity. The recombinant human GST-SYK (Carna Bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2017
Entry Details
US Patent

TargetTyrosine-protein kinase SYK(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 233630BDBM233630(US9353066, 1.83)
Affinity DataIC50: 7.60nMpH: 7.5 T: 2°CAssay Description:A recombinant GST-hSYK fusion protein was used to measure potency of compounds to inhibit human Syk activity. The recombinant human GST-SYK (Carna Bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2017
Entry Details
US Patent

TargetTyrosine-protein kinase SYK(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 233661BDBM233661(US9353066, 1.114)
Affinity DataIC50: 8nMpH: 7.5 T: 2°CAssay Description:A recombinant GST-hSYK fusion protein was used to measure potency of compounds to inhibit human Syk activity. The recombinant human GST-SYK (Carna Bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2017
Entry Details
US Patent

TargetTyrosine-protein kinase SYK(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 233671BDBM233671(US9353066, 1.124)
Affinity DataIC50: 8.5nMpH: 7.5 T: 2°CAssay Description:A recombinant GST-hSYK fusion protein was used to measure potency of compounds to inhibit human Syk activity. The recombinant human GST-SYK (Carna Bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2017
Entry Details
US Patent

TargetTyrosine-protein kinase SYK(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 233762BDBM233762(US9353066, 4.1)
Affinity DataIC50: 8.5nMpH: 7.5 T: 2°CAssay Description:A recombinant GST-hSYK fusion protein was used to measure potency of compounds to inhibit human Syk activity. The recombinant human GST-SYK (Carna Bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2017
Entry Details
US Patent

TargetTyrosine-protein kinase SYK(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 233724BDBM233724(US9353066, 3.22)
Affinity DataIC50: 9.10nMpH: 7.5 T: 2°CAssay Description:A recombinant GST-hSYK fusion protein was used to measure potency of compounds to inhibit human Syk activity. The recombinant human GST-SYK (Carna Bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2017
Entry Details
US Patent

TargetTyrosine-protein kinase SYK(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 233739BDBM233739(US9353066, 3.37)
Affinity DataIC50: 9.70nMpH: 7.5 T: 2°CAssay Description:A recombinant GST-hSYK fusion protein was used to measure potency of compounds to inhibit human Syk activity. The recombinant human GST-SYK (Carna Bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2017
Entry Details
US Patent

TargetTyrosine-protein kinase SYK(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 233700BDBM233700(US9353066, 2.8)
Affinity DataIC50: 9.90nMpH: 7.5 T: 2°CAssay Description:A recombinant GST-hSYK fusion protein was used to measure potency of compounds to inhibit human Syk activity. The recombinant human GST-SYK (Carna Bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2017
Entry Details
US Patent

TargetTyrosine-protein kinase SYK(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 233737BDBM233737(US9353066, 3.35)
Affinity DataIC50: 10.4nMpH: 7.5 T: 2°CAssay Description:A recombinant GST-hSYK fusion protein was used to measure potency of compounds to inhibit human Syk activity. The recombinant human GST-SYK (Carna Bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2017
Entry Details
US Patent

TargetTyrosine-protein kinase SYK(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 233736BDBM233736(US9353066, 3.34)
Affinity DataIC50: 10.6nMpH: 7.5 T: 2°CAssay Description:A recombinant GST-hSYK fusion protein was used to measure potency of compounds to inhibit human Syk activity. The recombinant human GST-SYK (Carna Bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2017
Entry Details
US Patent

TargetTyrosine-protein kinase SYK(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 233713BDBM233713(US9353066, 3.11)
Affinity DataIC50: 10.8nMpH: 7.5 T: 2°CAssay Description:A recombinant GST-hSYK fusion protein was used to measure potency of compounds to inhibit human Syk activity. The recombinant human GST-SYK (Carna Bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2017
Entry Details
US Patent

TargetTyrosine-protein kinase SYK(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 233662BDBM233662(US9353066, 1.115)
Affinity DataIC50: 10.8nMpH: 7.5 T: 2°CAssay Description:A recombinant GST-hSYK fusion protein was used to measure potency of compounds to inhibit human Syk activity. The recombinant human GST-SYK (Carna Bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2017
Entry Details
US Patent

TargetTyrosine-protein kinase SYK(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 233703BDBM233703(US9353066, 3.1)
Affinity DataIC50: 11.2nMpH: 7.5 T: 2°CAssay Description:A recombinant GST-hSYK fusion protein was used to measure potency of compounds to inhibit human Syk activity. The recombinant human GST-SYK (Carna Bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2017
Entry Details
US Patent

TargetTyrosine-protein kinase SYK(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 233648BDBM233648(US9353066, 1.101)
Affinity DataIC50: 11.3nMpH: 7.5 T: 2°CAssay Description:A recombinant GST-hSYK fusion protein was used to measure potency of compounds to inhibit human Syk activity. The recombinant human GST-SYK (Carna Bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2017
Entry Details
US Patent

TargetTyrosine-protein kinase SYK(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 233708BDBM233708(US9353066, 3.6)
Affinity DataIC50: 11.4nMpH: 7.5 T: 2°CAssay Description:A recombinant GST-hSYK fusion protein was used to measure potency of compounds to inhibit human Syk activity. The recombinant human GST-SYK (Carna Bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2017
Entry Details
US Patent

TargetTyrosine-protein kinase SYK(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 233710BDBM233710(US9353066, 3.8)
Affinity DataIC50: 11.5nMpH: 7.5 T: 2°CAssay Description:A recombinant GST-hSYK fusion protein was used to measure potency of compounds to inhibit human Syk activity. The recombinant human GST-SYK (Carna Bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2017
Entry Details
US Patent

TargetTyrosine-protein kinase SYK(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 233548BDBM233548(US9353066, 1.1)
Affinity DataIC50: 12.6nMpH: 7.5 T: 2°CAssay Description:A recombinant GST-hSYK fusion protein was used to measure potency of compounds to inhibit human Syk activity. The recombinant human GST-SYK (Carna Bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2017
Entry Details
US Patent

TargetTyrosine-protein kinase SYK(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 233709BDBM233709(US9353066, 3.7)
Affinity DataIC50: 13.7nMpH: 7.5 T: 2°CAssay Description:A recombinant GST-hSYK fusion protein was used to measure potency of compounds to inhibit human Syk activity. The recombinant human GST-SYK (Carna Bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2017
Entry Details
US Patent

TargetTyrosine-protein kinase SYK(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 233699BDBM233699(US9353066, 2.7)
Affinity DataIC50: 14nMpH: 7.5 T: 2°CAssay Description:A recombinant GST-hSYK fusion protein was used to measure potency of compounds to inhibit human Syk activity. The recombinant human GST-SYK (Carna Bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2017
Entry Details
US Patent

TargetTyrosine-protein kinase SYK(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 233723BDBM233723(US9353066, 3.21)
Affinity DataIC50: 14.3nMpH: 7.5 T: 2°CAssay Description:A recombinant GST-hSYK fusion protein was used to measure potency of compounds to inhibit human Syk activity. The recombinant human GST-SYK (Carna Bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2017
Entry Details
US Patent

TargetTyrosine-protein kinase SYK(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 233718BDBM233718(US9353066, 3.16)
Affinity DataIC50: 15nMpH: 7.5 T: 2°CAssay Description:A recombinant GST-hSYK fusion protein was used to measure potency of compounds to inhibit human Syk activity. The recombinant human GST-SYK (Carna Bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2017
Entry Details
US Patent

TargetTyrosine-protein kinase SYK(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 233689BDBM233689(US9353066, 1.143)
Affinity DataIC50: 15.8nMpH: 7.5 T: 2°CAssay Description:A recombinant GST-hSYK fusion protein was used to measure potency of compounds to inhibit human Syk activity. The recombinant human GST-SYK (Carna Bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2017
Entry Details
US Patent

TargetTyrosine-protein kinase SYK(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 233688BDBM233688(US9353066, 1.142)
Affinity DataIC50: 16nMpH: 7.5 T: 2°CAssay Description:A recombinant GST-hSYK fusion protein was used to measure potency of compounds to inhibit human Syk activity. The recombinant human GST-SYK (Carna Bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2017
Entry Details
US Patent

TargetTyrosine-protein kinase SYK(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 233725BDBM233725(US9353066, 3.23)
Affinity DataIC50: 16.3nMpH: 7.5 T: 2°CAssay Description:A recombinant GST-hSYK fusion protein was used to measure potency of compounds to inhibit human Syk activity. The recombinant human GST-SYK (Carna Bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2017
Entry Details
US Patent

TargetTyrosine-protein kinase SYK(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 233742BDBM233742(US9353066, 3.40)
Affinity DataIC50: 17.4nMpH: 7.5 T: 2°CAssay Description:A recombinant GST-hSYK fusion protein was used to measure potency of compounds to inhibit human Syk activity. The recombinant human GST-SYK (Carna Bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2017
Entry Details
US Patent

TargetTyrosine-protein kinase SYK(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 233727BDBM233727(US9353066, 3.25)
Affinity DataIC50: 17.4nMpH: 7.5 T: 2°CAssay Description:A recombinant GST-hSYK fusion protein was used to measure potency of compounds to inhibit human Syk activity. The recombinant human GST-SYK (Carna Bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2017
Entry Details
US Patent

TargetTyrosine-protein kinase SYK(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 233705BDBM233705(US9353066, 3.3)
Affinity DataIC50: 18.3nMpH: 7.5 T: 2°CAssay Description:A recombinant GST-hSYK fusion protein was used to measure potency of compounds to inhibit human Syk activity. The recombinant human GST-SYK (Carna Bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2017
Entry Details
US Patent

TargetTyrosine-protein kinase SYK(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 233647BDBM233647(US9353066, 1.100)
Affinity DataIC50: 18.4nMpH: 7.5 T: 2°CAssay Description:A recombinant GST-hSYK fusion protein was used to measure potency of compounds to inhibit human Syk activity. The recombinant human GST-SYK (Carna Bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2017
Entry Details
US Patent

TargetTyrosine-protein kinase SYK(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 233704BDBM233704(US9353066, 3.2)
Affinity DataIC50: 18.7nMpH: 7.5 T: 2°CAssay Description:A recombinant GST-hSYK fusion protein was used to measure potency of compounds to inhibit human Syk activity. The recombinant human GST-SYK (Carna Bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2017
Entry Details
US Patent

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