Compile Data Set for Download or QSAR
Report error Found 12 Enz. Inhib. hit(s) with all data for entry = 8156
TargetTyrosine-protein kinase BTK(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 235155BDBM235155(US9359345, 1)
Affinity DataIC50: 254nMpH: 7.15 T: 2°CAssay Description:This BTK competition assay measures compound potency (IC50) for the inactivated state of Bruton's Tyrosine Kinase using FRET (Forster/Fluorescence Re...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2017
Entry Details
US Patent

TargetTyrosine-protein kinase BTK(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 235161BDBM235161(US9359345, 7)
Affinity DataIC50: 470nMpH: 7.15 T: 2°CAssay Description:This BTK competition assay measures compound potency (IC50) for the inactivated state of Bruton's Tyrosine Kinase using FRET (Forster/Fluorescence Re...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2017
Entry Details
US Patent

TargetTyrosine-protein kinase BTK(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 235157BDBM235157(US9359345, 3)
Affinity DataIC50: 1.21E+3nMpH: 7.15 T: 2°CAssay Description:This BTK competition assay measures compound potency (IC50) for the inactivated state of Bruton's Tyrosine Kinase using FRET (Forster/Fluorescence Re...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2017
Entry Details
US Patent

TargetTyrosine-protein kinase BTK(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 235163BDBM235163(US9359345, 9)
Affinity DataIC50: 1.61E+3nMpH: 7.15 T: 2°CAssay Description:This BTK competition assay measures compound potency (IC50) for the inactivated state of Bruton's Tyrosine Kinase using FRET (Forster/Fluorescence Re...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2017
Entry Details
US Patent

TargetTyrosine-protein kinase BTK(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 235158BDBM235158(US9359345, 4)
Affinity DataIC50: 1.73E+3nMpH: 7.15 T: 2°CAssay Description:This BTK competition assay measures compound potency (IC50) for the inactivated state of Bruton's Tyrosine Kinase using FRET (Forster/Fluorescence Re...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2017
Entry Details
US Patent

TargetTyrosine-protein kinase BTK(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 235162BDBM235162(US9359345, 8)
Affinity DataIC50: 5.07E+3nMpH: 7.15 T: 2°CAssay Description:This BTK competition assay measures compound potency (IC50) for the inactivated state of Bruton's Tyrosine Kinase using FRET (Forster/Fluorescence Re...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2017
Entry Details
US Patent

TargetTyrosine-protein kinase BTK(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 235165BDBM235165(US9359345, 11)
Affinity DataIC50: 5.37E+3nMpH: 7.15 T: 2°CAssay Description:This BTK competition assay measures compound potency (IC50) for the inactivated state of Bruton's Tyrosine Kinase using FRET (Forster/Fluorescence Re...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2017
Entry Details
US Patent

TargetTyrosine-protein kinase BTK(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 235164BDBM235164(US9359345, 10)
Affinity DataIC50: 5.80E+3nMpH: 7.15 T: 2°CAssay Description:This BTK competition assay measures compound potency (IC50) for the inactivated state of Bruton's Tyrosine Kinase using FRET (Forster/Fluorescence Re...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2017
Entry Details
US Patent

TargetTyrosine-protein kinase BTK(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 235166BDBM235166(US9359345, 12)
Affinity DataIC50: 6.03E+3nMpH: 7.15 T: 2°CAssay Description:This BTK competition assay measures compound potency (IC50) for the inactivated state of Bruton's Tyrosine Kinase using FRET (Forster/Fluorescence Re...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2017
Entry Details
US Patent

TargetTyrosine-protein kinase BTK(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 235159BDBM235159(US9359345, 5)
Affinity DataIC50: 6.24E+3nMpH: 7.15 T: 2°CAssay Description:This BTK competition assay measures compound potency (IC50) for the inactivated state of Bruton's Tyrosine Kinase using FRET (Forster/Fluorescence Re...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2017
Entry Details
US Patent

TargetTyrosine-protein kinase BTK(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 235160BDBM235160(US9359345, 6)
Affinity DataIC50: 7.51E+3nMpH: 7.15 T: 2°CAssay Description:This BTK competition assay measures compound potency (IC50) for the inactivated state of Bruton's Tyrosine Kinase using FRET (Forster/Fluorescence Re...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2017
Entry Details
US Patent

TargetTyrosine-protein kinase BTK(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 235156BDBM235156(US9359345, 2)
Affinity DataIC50: 7.74E+3nMpH: 7.15 T: 2°CAssay Description:This BTK competition assay measures compound potency (IC50) for the inactivated state of Bruton's Tyrosine Kinase using FRET (Forster/Fluorescence Re...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2017
Entry Details
US Patent