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Report error Found 20 Enz. Inhib. hit(s) with all data for entry = 8261
TargetLysosomal acid glucosylceramidase(Human)
Amicus Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 238210BDBM238210(US9402837, 16)
Affinity DataKi:  440nM IC50: 1.07E+3nMpH: 4.5Assay Description:To 2.5 μl of supernatant (in 96-well plates) was added 17.5 μl reaction buffer (citrate phosphate buffer, pH 4.5, no Triton X-100), and 50 μ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/17/2017
Entry Details
US Patent

TargetLysosomal acid glucosylceramidase(Human)
Amicus Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 238214BDBM238214(US9402837, 24)
Affinity DataKi:  880nM IC50: 2.13E+3nMpH: 4.5Assay Description:To 2.5 μl of supernatant (in 96-well plates) was added 17.5 μl reaction buffer (citrate phosphate buffer, pH 4.5, no Triton X-100), and 50 μ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/17/2017
Entry Details
US Patent

TargetLysosomal acid glucosylceramidase(Human)
Amicus Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 238200BDBM238200(US9402837, 4)
Affinity DataKi:  1.66E+3nM IC50: 4.00E+3nMpH: 4.5Assay Description:To 2.5 μl of supernatant (in 96-well plates) was added 17.5 μl reaction buffer (citrate phosphate buffer, pH 4.5, no Triton X-100), and 50 μ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/17/2017
Entry Details
US Patent

TargetLysosomal acid glucosylceramidase(Human)
Amicus Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 238201BDBM238201(US9402837, 5)
Affinity DataKi:  2.48E+3nM IC50: 5.99E+3nMpH: 4.5Assay Description:To 2.5 μl of supernatant (in 96-well plates) was added 17.5 μl reaction buffer (citrate phosphate buffer, pH 4.5, no Triton X-100), and 50 μ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/17/2017
Entry Details
US Patent

TargetLysosomal acid glucosylceramidase(Human)
Amicus Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 238208BDBM238208(US9402837, 13)
Affinity DataKi:  3.11E+3nM IC50: 7.50E+3nMpH: 4.5Assay Description:To 2.5 μl of supernatant (in 96-well plates) was added 17.5 μl reaction buffer (citrate phosphate buffer, pH 4.5, no Triton X-100), and 50 μ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/17/2017
Entry Details
US Patent

TargetLysosomal acid glucosylceramidase(Human)
Amicus Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 238207BDBM238207(US9402837, 12)
Affinity DataKi:  3.88E+3nM IC50: 9.36E+3nMpH: 4.5Assay Description:To 2.5 μl of supernatant (in 96-well plates) was added 17.5 μl reaction buffer (citrate phosphate buffer, pH 4.5, no Triton X-100), and 50 μ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/17/2017
Entry Details
US Patent

TargetLysosomal acid glucosylceramidase(Human)
Amicus Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 238204BDBM238204(US9402837, 8)
Affinity DataKi:  5.26E+3nM IC50: 1.27E+4nMpH: 4.5Assay Description:To 2.5 μl of supernatant (in 96-well plates) was added 17.5 μl reaction buffer (citrate phosphate buffer, pH 4.5, no Triton X-100), and 50 μ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/17/2017
Entry Details
US Patent

TargetLysosomal acid glucosylceramidase(Human)
Amicus Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 238213BDBM238213(US9402837, 23)
Affinity DataKi:  6.48E+3nM IC50: 1.56E+4nMpH: 4.5Assay Description:To 2.5 μl of supernatant (in 96-well plates) was added 17.5 μl reaction buffer (citrate phosphate buffer, pH 4.5, no Triton X-100), and 50 μ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/17/2017
Entry Details
US Patent

TargetLysosomal acid glucosylceramidase(Human)
Amicus Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 238212BDBM238212(US9402837, 19)
Affinity DataKi:  8.02E+3nM IC50: 1.94E+4nMpH: 4.5Assay Description:To 2.5 μl of supernatant (in 96-well plates) was added 17.5 μl reaction buffer (citrate phosphate buffer, pH 4.5, no Triton X-100), and 50 μ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/17/2017
Entry Details
US Patent

TargetLysosomal acid glucosylceramidase(Human)
Amicus Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 238216BDBM238216(US9402837, 18)
Affinity DataKi:  1.14E+4nM IC50: 2.76E+4nMpH: 4.5Assay Description:To 2.5 μl of supernatant (in 96-well plates) was added 17.5 μl reaction buffer (citrate phosphate buffer, pH 4.5, no Triton X-100), and 50 μ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/17/2017
Entry Details
US Patent

TargetLysosomal acid glucosylceramidase(Human)
Amicus Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 238197BDBM238197(US9402837, 1)
Affinity DataKi:  1.48E+4nM IC50: 3.58E+4nMpH: 4.5Assay Description:To 2.5 μl of supernatant (in 96-well plates) was added 17.5 μl reaction buffer (citrate phosphate buffer, pH 4.5, no Triton X-100), and 50 μ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/17/2017
Entry Details
US Patent

TargetLysosomal acid glucosylceramidase(Human)
Amicus Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 238199BDBM238199(US9402837, 3)
Affinity DataKi:  1.73E+4nM IC50: 4.17E+4nMpH: 4.5Assay Description:To 2.5 μl of supernatant (in 96-well plates) was added 17.5 μl reaction buffer (citrate phosphate buffer, pH 4.5, no Triton X-100), and 50 μ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/17/2017
Entry Details
US Patent

TargetLysosomal acid glucosylceramidase(Human)
Amicus Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 238215BDBM238215(US9402837, 25)
Affinity DataKi:  1.86E+4nM IC50: 4.50E+4nMpH: 4.5Assay Description:To 2.5 μl of supernatant (in 96-well plates) was added 17.5 μl reaction buffer (citrate phosphate buffer, pH 4.5, no Triton X-100), and 50 μ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/17/2017
Entry Details
US Patent

TargetLysosomal acid glucosylceramidase(Human)
Amicus Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 238209BDBM238209(US9402837, 15)
Affinity DataKi:  2.04E+4nM IC50: 4.92E+4nMpH: 4.5Assay Description:To 2.5 μl of supernatant (in 96-well plates) was added 17.5 μl reaction buffer (citrate phosphate buffer, pH 4.5, no Triton X-100), and 50 μ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/17/2017
Entry Details
US Patent

TargetLysosomal acid glucosylceramidase(Human)
Amicus Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 238203BDBM238203(US9402837, 7)
Affinity DataKi:  2.88E+4nM IC50: 6.95E+4nMpH: 4.5Assay Description:To 2.5 μl of supernatant (in 96-well plates) was added 17.5 μl reaction buffer (citrate phosphate buffer, pH 4.5, no Triton X-100), and 50 μ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/17/2017
Entry Details
US Patent

TargetLysosomal acid glucosylceramidase(Human)
Amicus Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 238205BDBM238205(US9402837, 9)
Affinity DataKi:  5.37E+4nM IC50: 1.30E+5nMpH: 4.5Assay Description:To 2.5 μl of supernatant (in 96-well plates) was added 17.5 μl reaction buffer (citrate phosphate buffer, pH 4.5, no Triton X-100), and 50 μ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/17/2017
Entry Details
US Patent

TargetLysosomal acid glucosylceramidase(Human)
Amicus Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 238202BDBM238202(US9402837, 6)
Affinity DataKi:  8.30E+4nM IC50: 2.00E+5nMpH: 4.5Assay Description:To 2.5 μl of supernatant (in 96-well plates) was added 17.5 μl reaction buffer (citrate phosphate buffer, pH 4.5, no Triton X-100), and 50 μ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/17/2017
Entry Details
US Patent

TargetLysosomal acid glucosylceramidase(Human)
Amicus Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 238206BDBM238206(US9402837, 10)
Affinity DataKi:  1.12E+5nM IC50: 2.70E+5nMpH: 4.5Assay Description:To 2.5 μl of supernatant (in 96-well plates) was added 17.5 μl reaction buffer (citrate phosphate buffer, pH 4.5, no Triton X-100), and 50 μ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/17/2017
Entry Details
US Patent

TargetLysosomal acid glucosylceramidase(Human)
Amicus Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 238211BDBM238211(US9402837, 17)
Affinity DataKi:  1.16E+5nM IC50: 2.80E+5nMpH: 4.5Assay Description:To 2.5 μl of supernatant (in 96-well plates) was added 17.5 μl reaction buffer (citrate phosphate buffer, pH 4.5, no Triton X-100), and 50 μ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/17/2017
Entry Details
US Patent

TargetLysosomal acid glucosylceramidase(Human)
Amicus Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 238198BDBM238198(US9402837, 2)
Affinity DataKi:  4.06E+5nM IC50: 9.80E+5nMpH: 4.5Assay Description:To 2.5 μl of supernatant (in 96-well plates) was added 17.5 μl reaction buffer (citrate phosphate buffer, pH 4.5, no Triton X-100), and 50 μ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/17/2017
Entry Details
US Patent