Compile Data Set for Download or QSAR
Report error Found 22 Enz. Inhib. hit(s) with all data for entry = 8280
TargetEpidermal growth factor receptor(Human)
Pharmaxyn Laboratories

US Patent
LigandChemical structure of BindingDB Monomer ID 5446BDBM5446(Erlotinib | OSI-774 | N-(3-ethynylphenyl)-6,7-bis(...)
Affinity DataIC50: 30nMT: 2°CAssay Description:The kinase activity of EGFR was detected according to time-resolved fluorescence detection technology to evaluate automatic phosphorylation levels. T...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/24/2017
Entry Details
US Patent
PDB3D3D Structure (crystal)
TargetEpidermal growth factor receptor(Human)
Pharmaxyn Laboratories

US Patent
LigandChemical structure of BindingDB Monomer ID 50424964BDBM50424964(CHEMBL2316151 | US9409845, Table 1, Compound 12: (...)
Affinity DataIC50: 430nMT: 2°CAssay Description:The kinase activity of EGFR was detected according to time-resolved fluorescence detection technology to evaluate automatic phosphorylation levels. T...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/24/2017
Entry Details
US Patent

TargetEpidermal growth factor receptor(Human)
Pharmaxyn Laboratories

US Patent
LigandChemical structure of BindingDB Monomer ID 50424973BDBM50424973(CHEMBL2316142 | US9409845, Table 1, Compound 3: (2...)
Affinity DataIC50: 1.54E+3nMT: 2°CAssay Description:The kinase activity of EGFR was detected according to time-resolved fluorescence detection technology to evaluate automatic phosphorylation levels. T...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/24/2017
Entry Details
US Patent

TargetEpidermal growth factor receptor(Human)
Pharmaxyn Laboratories

US Patent
LigandChemical structure of BindingDB Monomer ID 50424975BDBM50424975(CHEMBL2316140 | US9409845, Table 1, Compound 1: (2...)
Affinity DataIC50: 1.68E+3nMT: 2°CAssay Description:The kinase activity of EGFR was detected according to time-resolved fluorescence detection technology to evaluate automatic phosphorylation levels. T...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/24/2017
Entry Details
US Patent

TargetEpidermal growth factor receptor(Human)
Pharmaxyn Laboratories

US Patent
LigandChemical structure of BindingDB Monomer ID 50424957BDBM50424957(CHEMBL2316158 | US9409845, Table 1, Compound 19: (...)
Affinity DataIC50: 1.96E+3nMT: 2°CAssay Description:The kinase activity of EGFR was detected according to time-resolved fluorescence detection technology to evaluate automatic phosphorylation levels. T...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/24/2017
Entry Details
US Patent

TargetEpidermal growth factor receptor(Human)
Pharmaxyn Laboratories

US Patent
LigandChemical structure of BindingDB Monomer ID 50424958BDBM50424958(CHEMBL2316157 | US9409845, Table 1, Compound 18: (...)
Affinity DataIC50: 2.08E+3nMT: 2°CAssay Description:The kinase activity of EGFR was detected according to time-resolved fluorescence detection technology to evaluate automatic phosphorylation levels. T...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/24/2017
Entry Details
US Patent

TargetEpidermal growth factor receptor(Human)
Pharmaxyn Laboratories

US Patent
LigandChemical structure of BindingDB Monomer ID 50424972BDBM50424972(CHEMBL2316143 | US9409845, Table 1, Compound 4: (2...)
Affinity DataIC50: 2.17E+3nMT: 2°CAssay Description:The kinase activity of EGFR was detected according to time-resolved fluorescence detection technology to evaluate automatic phosphorylation levels. T...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/24/2017
Entry Details
US Patent

TargetEpidermal growth factor receptor(Human)
Pharmaxyn Laboratories

US Patent
LigandChemical structure of BindingDB Monomer ID 50424974BDBM50424974(CHEMBL2316141 | US9409845, Table 1, Compound 2: (2...)
Affinity DataIC50: 2.27E+3nMT: 2°CAssay Description:The kinase activity of EGFR was detected according to time-resolved fluorescence detection technology to evaluate automatic phosphorylation levels. T...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/24/2017
Entry Details
US Patent

TargetEpidermal growth factor receptor(Human)
Pharmaxyn Laboratories

US Patent
LigandChemical structure of BindingDB Monomer ID 50424961BDBM50424961(CHEMBL2316154 | US9409845, Table 1, Compound 15: (...)
Affinity DataIC50: 3.98E+3nMT: 2°CAssay Description:The kinase activity of EGFR was detected according to time-resolved fluorescence detection technology to evaluate automatic phosphorylation levels. T...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/24/2017
Entry Details
US Patent

TargetEpidermal growth factor receptor(Human)
Pharmaxyn Laboratories

US Patent
LigandChemical structure of BindingDB Monomer ID 50424962BDBM50424962(CHEMBL2316153 | US9409845, Table 1, Compound 14: (...)
Affinity DataIC50: 4.66E+3nMT: 2°CAssay Description:The kinase activity of EGFR was detected according to time-resolved fluorescence detection technology to evaluate automatic phosphorylation levels. T...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/24/2017
Entry Details
US Patent

TargetEpidermal growth factor receptor(Human)
Pharmaxyn Laboratories

US Patent
LigandChemical structure of BindingDB Monomer ID 50424956BDBM50424956(CHEMBL2316159 | US9409845, Table 1, Compound 20: (...)
Affinity DataIC50: 4.81E+3nMT: 2°CAssay Description:The kinase activity of EGFR was detected according to time-resolved fluorescence detection technology to evaluate automatic phosphorylation levels. T...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/24/2017
Entry Details
US Patent

TargetEpidermal growth factor receptor(Human)
Pharmaxyn Laboratories

US Patent
LigandChemical structure of BindingDB Monomer ID 50424960BDBM50424960(CHEMBL2316155 | US9409845, Table 1, Compound 16: (...)
Affinity DataIC50: 5.37E+3nMT: 2°CAssay Description:The kinase activity of EGFR was detected according to time-resolved fluorescence detection technology to evaluate automatic phosphorylation levels. T...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/24/2017
Entry Details
US Patent

TargetEpidermal growth factor receptor(Human)
Pharmaxyn Laboratories

US Patent
LigandChemical structure of BindingDB Monomer ID 50424968BDBM50424968(CHEMBL2316147 | US9409845, Table 1, Compound 8: (2...)
Affinity DataIC50: 5.69E+3nMT: 2°CAssay Description:The kinase activity of EGFR was detected according to time-resolved fluorescence detection technology to evaluate automatic phosphorylation levels. T...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/24/2017
Entry Details
US Patent

TargetEpidermal growth factor receptor(Human)
Pharmaxyn Laboratories

US Patent
LigandChemical structure of BindingDB Monomer ID 50424965BDBM50424965(CHEMBL2316150 | US9409845, Table 1, Compound 11: (...)
Affinity DataIC50: 6.13E+3nMT: 2°CAssay Description:The kinase activity of EGFR was detected according to time-resolved fluorescence detection technology to evaluate automatic phosphorylation levels. T...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/24/2017
Entry Details
US Patent

TargetEpidermal growth factor receptor(Human)
Pharmaxyn Laboratories

US Patent
LigandChemical structure of BindingDB Monomer ID 50424970BDBM50424970(CHEMBL2316145 | US9409845, Table 1, Compound 6: (2...)
Affinity DataIC50: 6.85E+3nMT: 2°CAssay Description:The kinase activity of EGFR was detected according to time-resolved fluorescence detection technology to evaluate automatic phosphorylation levels. T...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/24/2017
Entry Details
US Patent

TargetEpidermal growth factor receptor(Human)
Pharmaxyn Laboratories

US Patent
LigandChemical structure of BindingDB Monomer ID 50424969BDBM50424969(CHEMBL2316146 | US9409845, Table 1, Compound 7: (2...)
Affinity DataIC50: 7.12E+3nMT: 2°CAssay Description:The kinase activity of EGFR was detected according to time-resolved fluorescence detection technology to evaluate automatic phosphorylation levels. T...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/24/2017
Entry Details
US Patent

TargetEpidermal growth factor receptor(Human)
Pharmaxyn Laboratories

US Patent
LigandChemical structure of BindingDB Monomer ID 50424966BDBM50424966(CHEMBL2316149 | US9409845, Table 1, Compound 10: (...)
Affinity DataIC50: 7.52E+3nMT: 2°CAssay Description:The kinase activity of EGFR was detected according to time-resolved fluorescence detection technology to evaluate automatic phosphorylation levels. T...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/24/2017
Entry Details
US Patent

TargetEpidermal growth factor receptor(Human)
Pharmaxyn Laboratories

US Patent
LigandChemical structure of BindingDB Monomer ID 50424971BDBM50424971(CHEMBL2316144 | US9409845, Table 1, Compound 5: (2...)
Affinity DataIC50: 8.08E+3nMT: 2°CAssay Description:The kinase activity of EGFR was detected according to time-resolved fluorescence detection technology to evaluate automatic phosphorylation levels. T...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/24/2017
Entry Details
US Patent

TargetEpidermal growth factor receptor(Human)
Pharmaxyn Laboratories

US Patent
LigandChemical structure of BindingDB Monomer ID 50140172BDBM50140172(CHEBI:3962 | CHEMBL140 | Curcumin | US9409845, Tab...)
Affinity DataIC50: 8.65E+3nMT: 2°CAssay Description:The kinase activity of EGFR was detected according to time-resolved fluorescence detection technology to evaluate automatic phosphorylation levels. T...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/24/2017
Entry Details
US Patent

TargetEpidermal growth factor receptor(Human)
Pharmaxyn Laboratories

US Patent
LigandChemical structure of BindingDB Monomer ID 50424967BDBM50424967(CHEMBL2316148 | US9409845, Table 1, Compound 9: (2...)
Affinity DataIC50: 1.53E+4nMT: 2°CAssay Description:The kinase activity of EGFR was detected according to time-resolved fluorescence detection technology to evaluate automatic phosphorylation levels. T...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/24/2017
Entry Details
US Patent

TargetEpidermal growth factor receptor(Human)
Pharmaxyn Laboratories

US Patent
LigandChemical structure of BindingDB Monomer ID 239058BDBM239058(US9409845, Table 1, Compound 17: (2E,6E)-2-di-(3,5...)
Affinity DataIC50: 1.87E+4nMT: 2°CAssay Description:The kinase activity of EGFR was detected according to time-resolved fluorescence detection technology to evaluate automatic phosphorylation levels. T...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/24/2017
Entry Details
US Patent

TargetEpidermal growth factor receptor(Human)
Pharmaxyn Laboratories

US Patent
LigandChemical structure of BindingDB Monomer ID 50424963BDBM50424963(CHEMBL2316152 | US9409845, Table 1, Compound 13: (...)
Affinity DataIC50: 2.09E+4nMT: 2°CAssay Description:The kinase activity of EGFR was detected according to time-resolved fluorescence detection technology to evaluate automatic phosphorylation levels. T...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/24/2017
Entry Details
US Patent