Compile Data Set for Download or QSAR
Report error Found 208 Enz. Inhib. hit(s) with all data for entry = 8390
TargetBromodomain-containing protein 4 [352-457](Human)
Abbvie

US Patent
LigandChemical structure of BindingDB Monomer ID 245884BDBM245884(US9428514, 72)
Affinity DataKi:  2.28nM ΔG°:  -49.3kJ/molepH: 6.0 T: 2°CAssay Description:Assay method C: Compound dilution series were prepared in DMSO via an approximately 3-fold serial dilution from one of the following: 0.047 mM to 0.7...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2017
Entry Details
US Patent

TargetBromodomain-containing protein 4 [352-457](Human)
Abbvie

US Patent
LigandChemical structure of BindingDB Monomer ID 245911BDBM245911(US9428514, 99)
Affinity DataKi:  4.58nM ΔG°:  -47.6kJ/molepH: 6.0 T: 2°CAssay Description:Assay method C: Compound dilution series were prepared in DMSO via an approximately 3-fold serial dilution from one of the following: 0.047 mM to 0.7...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2017
Entry Details
US Patent

TargetBromodomain-containing protein 4 [352-457](Human)
Abbvie

US Patent
LigandChemical structure of BindingDB Monomer ID 245847BDBM245847(US9428514, 35)
Affinity DataKi:  9.36nM ΔG°:  -45.8kJ/molepH: 6.0 T: 2°CAssay Description:Assay method B: Compound dilution series were prepared in DMSO via an approximately 3-fold serial dilution from one of the following: 0.47 mM to 7.8 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2017
Entry Details
US Patent

TargetBromodomain-containing protein 4 [352-457](Human)
Abbvie

US Patent
LigandChemical structure of BindingDB Monomer ID 245885BDBM245885(US9428514, 73)
Affinity DataKi:  9.66nM ΔG°:  -45.7kJ/molepH: 6.0 T: 2°CAssay Description:Assay method C: Compound dilution series were prepared in DMSO via an approximately 3-fold serial dilution from one of the following: 0.047 mM to 0.7...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2017
Entry Details
US Patent

TargetBromodomain-containing protein 4 [352-457](Human)
Abbvie

US Patent
LigandChemical structure of BindingDB Monomer ID 245853BDBM245853(US9428514, 41)
Affinity DataKi:  10.8nM ΔG°:  -45.5kJ/molepH: 6.0 T: 2°CAssay Description:Assay method B: Compound dilution series were prepared in DMSO via an approximately 3-fold serial dilution from one of the following: 0.47 mM to 7.8 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2017
Entry Details
US Patent

TargetBromodomain-containing protein 4 [352-457](Human)
Abbvie

US Patent
LigandChemical structure of BindingDB Monomer ID 245915BDBM245915(US9428514, 103)
Affinity DataKi:  11.7nM ΔG°:  -45.3kJ/molepH: 6.0 T: 2°CAssay Description:Assay method C: Compound dilution series were prepared in DMSO via an approximately 3-fold serial dilution from one of the following: 0.047 mM to 0.7...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2017
Entry Details
US Patent

TargetBromodomain-containing protein 4 [352-457](Human)
Abbvie

US Patent
LigandChemical structure of BindingDB Monomer ID 245888BDBM245888(US9428514, 76)
Affinity DataKi:  13.1nM ΔG°:  -45.0kJ/molepH: 6.0 T: 2°CAssay Description:Assay method C: Compound dilution series were prepared in DMSO via an approximately 3-fold serial dilution from one of the following: 0.047 mM to 0.7...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2017
Entry Details
US Patent

TargetBromodomain-containing protein 4 [352-457](Human)
Abbvie

US Patent
LigandChemical structure of BindingDB Monomer ID 245886BDBM245886(US9428514, 74)
Affinity DataKi:  13.5nM ΔG°:  -44.9kJ/molepH: 6.0 T: 2°CAssay Description:Assay method C: Compound dilution series were prepared in DMSO via an approximately 3-fold serial dilution from one of the following: 0.047 mM to 0.7...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2017
Entry Details
US Patent

TargetBromodomain-containing protein 4 [352-457](Human)
Abbvie

US Patent
LigandChemical structure of BindingDB Monomer ID 245909BDBM245909(US9428514, 97)
Affinity DataKi:  17.3nM ΔG°:  -44.3kJ/molepH: 6.0 T: 2°CAssay Description:Assay method C: Compound dilution series were prepared in DMSO via an approximately 3-fold serial dilution from one of the following: 0.047 mM to 0.7...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2017
Entry Details
US Patent

TargetBromodomain-containing protein 4 [352-457](Human)
Abbvie

US Patent
LigandChemical structure of BindingDB Monomer ID 245903BDBM245903(US9428514, 91)
Affinity DataKi:  17.6nM ΔG°:  -44.3kJ/molepH: 6.0 T: 2°CAssay Description:Assay method C: Compound dilution series were prepared in DMSO via an approximately 3-fold serial dilution from one of the following: 0.047 mM to 0.7...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2017
Entry Details
US Patent

TargetBromodomain-containing protein 4 [352-457](Human)
Abbvie

US Patent
LigandChemical structure of BindingDB Monomer ID 245893BDBM245893(US9428514, 81)
Affinity DataKi:  21.9nM ΔG°:  -43.7kJ/molepH: 6.0 T: 2°CAssay Description:Assay method C: Compound dilution series were prepared in DMSO via an approximately 3-fold serial dilution from one of the following: 0.047 mM to 0.7...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2017
Entry Details
US Patent

TargetBromodomain-containing protein 4 [352-457](Human)
Abbvie

US Patent
LigandChemical structure of BindingDB Monomer ID 245898BDBM245898(US9428514, 86)
Affinity DataKi:  22.6nM ΔG°:  -43.6kJ/molepH: 6.0 T: 2°CAssay Description:Assay method C: Compound dilution series were prepared in DMSO via an approximately 3-fold serial dilution from one of the following: 0.047 mM to 0.7...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2017
Entry Details
US Patent

TargetBromodomain-containing protein 4 [352-457](Human)
Abbvie

US Patent
LigandChemical structure of BindingDB Monomer ID 245914BDBM245914(US9428514, 102)
Affinity DataKi:  23.7nM ΔG°:  -43.5kJ/molepH: 6.0 T: 2°CAssay Description:Assay method C: Compound dilution series were prepared in DMSO via an approximately 3-fold serial dilution from one of the following: 0.047 mM to 0.7...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2017
Entry Details
US Patent

TargetBromodomain-containing protein 4 [352-457](Human)
Abbvie

US Patent
LigandChemical structure of BindingDB Monomer ID 245916BDBM245916(US9428514, 104)
Affinity DataKi:  23.9nM ΔG°:  -43.5kJ/molepH: 6.0 T: 2°CAssay Description:Assay method C: Compound dilution series were prepared in DMSO via an approximately 3-fold serial dilution from one of the following: 0.047 mM to 0.7...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2017
Entry Details
US Patent

TargetBromodomain-containing protein 4 [352-457](Human)
Abbvie

US Patent
LigandChemical structure of BindingDB Monomer ID 245813BDBM245813(US9428514, 1)
Affinity DataKi:  24.6nM ΔG°:  -43.4kJ/molepH: 6.0 T: 2°CAssay Description:Assay method B: Compound dilution series were prepared in DMSO via an approximately 3-fold serial dilution from one of the following: 0.47 mM to 7.8 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2017
Entry Details
US Patent

TargetBromodomain-containing protein 4 [352-457](Human)
Abbvie

US Patent
LigandChemical structure of BindingDB Monomer ID 245828BDBM245828(US9428514, 16)
Affinity DataKi:  28.2nM ΔG°:  -43.1kJ/molepH: 6.0 T: 2°CAssay Description:Assay method B: Compound dilution series were prepared in DMSO via an approximately 3-fold serial dilution from one of the following: 0.47 mM to 7.8 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2017
Entry Details
US Patent

TargetBromodomain-containing protein 4 [352-457](Human)
Abbvie

US Patent
LigandChemical structure of BindingDB Monomer ID 245907BDBM245907(US9428514, 95)
Affinity DataKi:  28.9nM ΔG°:  -43.0kJ/molepH: 6.0 T: 2°CAssay Description:Assay method C: Compound dilution series were prepared in DMSO via an approximately 3-fold serial dilution from one of the following: 0.047 mM to 0.7...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2017
Entry Details
US Patent

TargetBromodomain-containing protein 4 [352-457](Human)
Abbvie

US Patent
LigandChemical structure of BindingDB Monomer ID 245912BDBM245912(US9428514, 100)
Affinity DataKi:  34.6nM ΔG°:  -42.6kJ/molepH: 6.0 T: 2°CAssay Description:Assay method C: Compound dilution series were prepared in DMSO via an approximately 3-fold serial dilution from one of the following: 0.047 mM to 0.7...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2017
Entry Details
US Patent

TargetBromodomain-containing protein 4 [352-457](Human)
Abbvie

US Patent
LigandChemical structure of BindingDB Monomer ID 245895BDBM245895(US9428514, 83)
Affinity DataKi:  36.5nM ΔG°:  -42.5kJ/molepH: 6.0 T: 2°CAssay Description:Assay method C: Compound dilution series were prepared in DMSO via an approximately 3-fold serial dilution from one of the following: 0.047 mM to 0.7...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2017
Entry Details
US Patent

TargetBromodomain-containing protein 4 [352-457](Human)
Abbvie

US Patent
LigandChemical structure of BindingDB Monomer ID 245839BDBM245839(US9428514, 27)
Affinity DataKi:  36.5nM ΔG°:  -42.5kJ/molepH: 6.0 T: 2°CAssay Description:Assay method B: Compound dilution series were prepared in DMSO via an approximately 3-fold serial dilution from one of the following: 0.47 mM to 7.8 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2017
Entry Details
US Patent

TargetBromodomain-containing protein 4 [352-457](Human)
Abbvie

US Patent
LigandChemical structure of BindingDB Monomer ID 245845BDBM245845(US9428514, 33)
Affinity DataKi:  36.9nM ΔG°:  -42.4kJ/molepH: 6.0 T: 2°CAssay Description:Assay method B: Compound dilution series were prepared in DMSO via an approximately 3-fold serial dilution from one of the following: 0.47 mM to 7.8 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2017
Entry Details
US Patent

TargetBromodomain-containing protein 4 [352-457](Human)
Abbvie

US Patent
LigandChemical structure of BindingDB Monomer ID 245878BDBM245878(US9428514, 66)
Affinity DataKi:  38.4nM ΔG°:  -42.3kJ/molepH: 6.0 T: 2°CAssay Description:Assay method C: Compound dilution series were prepared in DMSO via an approximately 3-fold serial dilution from one of the following: 0.047 mM to 0.7...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2017
Entry Details
US Patent

TargetBromodomain-containing protein 4 [352-457](Human)
Abbvie

US Patent
LigandChemical structure of BindingDB Monomer ID 245851BDBM245851(US9428514, 39)
Affinity DataKi:  38.8nM ΔG°:  -42.3kJ/molepH: 6.0 T: 2°CAssay Description:Assay method B: Compound dilution series were prepared in DMSO via an approximately 3-fold serial dilution from one of the following: 0.47 mM to 7.8 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2017
Entry Details
US Patent

TargetBromodomain-containing protein 4 [352-457](Human)
Abbvie

US Patent
LigandChemical structure of BindingDB Monomer ID 245842BDBM245842(US9428514, 30)
Affinity DataKi:  38.9nM ΔG°:  -42.3kJ/molepH: 6.0 T: 2°CAssay Description:Assay method B: Compound dilution series were prepared in DMSO via an approximately 3-fold serial dilution from one of the following: 0.47 mM to 7.8 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2017
Entry Details
US Patent

TargetBromodomain-containing protein 4 [352-457](Human)
Abbvie

US Patent
LigandChemical structure of BindingDB Monomer ID 245902BDBM245902(US9428514, 90)
Affinity DataKi:  44.4nM ΔG°:  -42.0kJ/molepH: 6.0 T: 2°CAssay Description:Assay method C: Compound dilution series were prepared in DMSO via an approximately 3-fold serial dilution from one of the following: 0.047 mM to 0.7...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2017
Entry Details
US Patent

TargetBromodomain-containing protein 4 [352-457](Human)
Abbvie

US Patent
LigandChemical structure of BindingDB Monomer ID 245860BDBM245860(US9428514, 48)
Affinity DataKi:  46.8nM ΔG°:  -41.8kJ/molepH: 6.0 T: 2°CAssay Description:Assay method B: Compound dilution series were prepared in DMSO via an approximately 3-fold serial dilution from one of the following: 0.47 mM to 7.8 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2017
Entry Details
US Patent

TargetBromodomain-containing protein 4 [352-457](Human)
Abbvie

US Patent
LigandChemical structure of BindingDB Monomer ID 245858BDBM245858(US9428514, 46)
Affinity DataKi:  47.7nM ΔG°:  -41.8kJ/molepH: 6.0 T: 2°CAssay Description:Assay method B: Compound dilution series were prepared in DMSO via an approximately 3-fold serial dilution from one of the following: 0.47 mM to 7.8 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2017
Entry Details
US Patent

TargetBromodomain-containing protein 4 [352-457](Human)
Abbvie

US Patent
LigandChemical structure of BindingDB Monomer ID 245887BDBM245887(US9428514, 75)
Affinity DataKi:  47.8nM ΔG°:  -41.8kJ/molepH: 6.0 T: 2°CAssay Description:Assay method C: Compound dilution series were prepared in DMSO via an approximately 3-fold serial dilution from one of the following: 0.047 mM to 0.7...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2017
Entry Details
US Patent

TargetBromodomain-containing protein 4 [352-457](Human)
Abbvie

US Patent
LigandChemical structure of BindingDB Monomer ID 245841BDBM245841(US9428514, 29)
Affinity DataKi:  50.7nM ΔG°:  -41.6kJ/molepH: 6.0 T: 2°CAssay Description:Assay method B: Compound dilution series were prepared in DMSO via an approximately 3-fold serial dilution from one of the following: 0.47 mM to 7.8 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2017
Entry Details
US Patent

TargetBromodomain-containing protein 4 [352-457](Human)
Abbvie

US Patent
LigandChemical structure of BindingDB Monomer ID 245840BDBM245840(US9428514, 28)
Affinity DataKi:  54.1nM ΔG°:  -41.5kJ/molepH: 6.0 T: 2°CAssay Description:Assay method B: Compound dilution series were prepared in DMSO via an approximately 3-fold serial dilution from one of the following: 0.47 mM to 7.8 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2017
Entry Details
US Patent

TargetBromodomain-containing protein 4 [352-457](Human)
Abbvie

US Patent
LigandChemical structure of BindingDB Monomer ID 245852BDBM245852(US9428514, 40)
Affinity DataKi:  54.2nM ΔG°:  -41.5kJ/molepH: 6.0 T: 2°CAssay Description:Assay method B: Compound dilution series were prepared in DMSO via an approximately 3-fold serial dilution from one of the following: 0.47 mM to 7.8 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2017
Entry Details
US Patent

TargetBromodomain-containing protein 4 [352-457](Human)
Abbvie

US Patent
LigandChemical structure of BindingDB Monomer ID 245892BDBM245892(US9428514, 80)
Affinity DataKi:  56.1nM ΔG°:  -41.4kJ/molepH: 6.0 T: 2°CAssay Description:Assay method C: Compound dilution series were prepared in DMSO via an approximately 3-fold serial dilution from one of the following: 0.047 mM to 0.7...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2017
Entry Details
US Patent

TargetBromodomain-containing protein 4 [352-457](Human)
Abbvie

US Patent
LigandChemical structure of BindingDB Monomer ID 245905BDBM245905(US9428514, 93)
Affinity DataKi:  56.3nM ΔG°:  -41.4kJ/molepH: 6.0 T: 2°CAssay Description:Assay method C: Compound dilution series were prepared in DMSO via an approximately 3-fold serial dilution from one of the following: 0.047 mM to 0.7...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2017
Entry Details
US Patent

TargetBromodomain-containing protein 4 [352-457](Human)
Abbvie

US Patent
LigandChemical structure of BindingDB Monomer ID 245859BDBM245859(US9428514, 47)
Affinity DataKi:  56.7nM ΔG°:  -41.4kJ/molepH: 6.0 T: 2°CAssay Description:Assay method B: Compound dilution series were prepared in DMSO via an approximately 3-fold serial dilution from one of the following: 0.47 mM to 7.8 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2017
Entry Details
US Patent

TargetBromodomain-containing protein 4 [352-457](Human)
Abbvie

US Patent
LigandChemical structure of BindingDB Monomer ID 245843BDBM245843(US9428514, 31)
Affinity DataKi:  57.9nM ΔG°:  -41.3kJ/molepH: 6.0 T: 2°CAssay Description:Assay method B: Compound dilution series were prepared in DMSO via an approximately 3-fold serial dilution from one of the following: 0.47 mM to 7.8 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2017
Entry Details
US Patent

TargetBromodomain-containing protein 4 [352-457](Human)
Abbvie

US Patent
LigandChemical structure of BindingDB Monomer ID 245868BDBM245868(US9428514, 56)
Affinity DataKi:  60.1nM ΔG°:  -41.2kJ/molepH: 6.0 T: 2°CAssay Description:Assay method B: Compound dilution series were prepared in DMSO via an approximately 3-fold serial dilution from one of the following: 0.47 mM to 7.8 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2017
Entry Details
US Patent

TargetBromodomain-containing protein 4 [57-168](Human)
Abbvie

US Patent
LigandChemical structure of BindingDB Monomer ID 245884BDBM245884(US9428514, 72)
Affinity DataKi:  60.9nM ΔG°:  -41.2kJ/molepH: 6.0 T: 2°CAssay Description:Assay method C: Compound dilution series were prepared in DMSO via an approximately 3-fold serial dilution from one of the following: 0.047 mM to 0.7...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2017
Entry Details
US Patent

TargetBromodomain-containing protein 4 [352-457](Human)
Abbvie

US Patent
LigandChemical structure of BindingDB Monomer ID 245826BDBM245826(US9428514, 14)
Affinity DataKi:  61.6nM ΔG°:  -41.2kJ/molepH: 6.0 T: 2°CAssay Description:Assay method B: Compound dilution series were prepared in DMSO via an approximately 3-fold serial dilution from one of the following: 0.47 mM to 7.8 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2017
Entry Details
US Patent

TargetBromodomain-containing protein 4 [352-457](Human)
Abbvie

US Patent
LigandChemical structure of BindingDB Monomer ID 245876BDBM245876(US9428514, 64)
Affinity DataKi:  61.8nM ΔG°:  -41.1kJ/molepH: 6.0 T: 2°CAssay Description:Assay method C: Compound dilution series were prepared in DMSO via an approximately 3-fold serial dilution from one of the following: 0.047 mM to 0.7...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2017
Entry Details
US Patent

TargetBromodomain-containing protein 4 [352-457](Human)
Abbvie

US Patent
LigandChemical structure of BindingDB Monomer ID 245894BDBM245894(US9428514, 82)
Affinity DataKi:  63nM ΔG°:  -41.1kJ/molepH: 6.0 T: 2°CAssay Description:Assay method C: Compound dilution series were prepared in DMSO via an approximately 3-fold serial dilution from one of the following: 0.047 mM to 0.7...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2017
Entry Details
US Patent

TargetBromodomain-containing protein 4 [352-457](Human)
Abbvie

US Patent
LigandChemical structure of BindingDB Monomer ID 245821BDBM245821(US9428514, 9)
Affinity DataKi:  63.2nM ΔG°:  -41.1kJ/molepH: 6.0 T: 2°CAssay Description:Assay method A: Compound dilution series were prepared in DMSO via an approximately 3-fold serial dilution from one of the following: 2.5 mM-797 nM. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2017
Entry Details
US Patent

TargetBromodomain-containing protein 4 [352-457](Human)
Abbvie

US Patent
LigandChemical structure of BindingDB Monomer ID 245817BDBM245817(US9428514, 5)
Affinity DataKi:  65.5nM ΔG°:  -41.0kJ/molepH: 6.0 T: 2°CAssay Description:Assay method C: Compound dilution series were prepared in DMSO via an approximately 3-fold serial dilution from one of the following: 0.047 mM to 0.7...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2017
Entry Details
US Patent

TargetBromodomain-containing protein 4 [352-457](Human)
Abbvie

US Patent
LigandChemical structure of BindingDB Monomer ID 245848BDBM245848(US9428514, 36)
Affinity DataKi:  66.2nM ΔG°:  -41.0kJ/molepH: 6.0 T: 2°CAssay Description:Assay method B: Compound dilution series were prepared in DMSO via an approximately 3-fold serial dilution from one of the following: 0.47 mM to 7.8 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2017
Entry Details
US Patent

TargetBromodomain-containing protein 4 [352-457](Human)
Abbvie

US Patent
LigandChemical structure of BindingDB Monomer ID 245896BDBM245896(US9428514, 84)
Affinity DataKi:  67.5nM ΔG°:  -40.9kJ/molepH: 6.0 T: 2°CAssay Description:Assay method C: Compound dilution series were prepared in DMSO via an approximately 3-fold serial dilution from one of the following: 0.047 mM to 0.7...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2017
Entry Details
US Patent

TargetBromodomain-containing protein 4 [57-168](Human)
Abbvie

US Patent
LigandChemical structure of BindingDB Monomer ID 245853BDBM245853(US9428514, 41)
Affinity DataKi:  68.5nM ΔG°:  -40.9kJ/molepH: 6.0 T: 2°CAssay Description:Assay method B: Compound dilution series were prepared in DMSO via an approximately 3-fold serial dilution from one of the following: 0.47 mM to 7.8 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2017
Entry Details
US Patent

TargetBromodomain-containing protein 4 [352-457](Human)
Abbvie

US Patent
LigandChemical structure of BindingDB Monomer ID 245849BDBM245849(US9428514, 37)
Affinity DataKi:  69.4nM ΔG°:  -40.9kJ/molepH: 6.0 T: 2°CAssay Description:Assay method B: Compound dilution series were prepared in DMSO via an approximately 3-fold serial dilution from one of the following: 0.47 mM to 7.8 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2017
Entry Details
US Patent

TargetBromodomain-containing protein 4 [352-457](Human)
Abbvie

US Patent
LigandChemical structure of BindingDB Monomer ID 245890BDBM245890(US9428514, 78)
Affinity DataKi:  71.3nM ΔG°:  -40.8kJ/molepH: 6.0 T: 2°CAssay Description:Assay method C: Compound dilution series were prepared in DMSO via an approximately 3-fold serial dilution from one of the following: 0.047 mM to 0.7...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2017
Entry Details
US Patent

TargetBromodomain-containing protein 4 [352-457](Human)
Abbvie

US Patent
LigandChemical structure of BindingDB Monomer ID 245838BDBM245838(US9428514, 26)
Affinity DataKi:  71.4nM ΔG°:  -40.8kJ/molepH: 6.0 T: 2°CAssay Description:Assay method B: Compound dilution series were prepared in DMSO via an approximately 3-fold serial dilution from one of the following: 0.47 mM to 7.8 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2017
Entry Details
US Patent

TargetBromodomain-containing protein 4 [57-168](Human)
Abbvie

US Patent
LigandChemical structure of BindingDB Monomer ID 245845BDBM245845(US9428514, 33)
Affinity DataKi:  71.8nM ΔG°:  -40.8kJ/molepH: 6.0 T: 2°CAssay Description:Assay method B: Compound dilution series were prepared in DMSO via an approximately 3-fold serial dilution from one of the following: 0.47 mM to 7.8 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2017
Entry Details
US Patent

TargetBromodomain-containing protein 4 [352-457](Human)
Abbvie

US Patent
LigandChemical structure of BindingDB Monomer ID 245850BDBM245850(US9428514, 38)
Affinity DataKi:  74.8nM ΔG°:  -40.7kJ/molepH: 6.0 T: 2°CAssay Description:Assay method C: Compound dilution series were prepared in DMSO via an approximately 3-fold serial dilution from one of the following: 0.047 mM to 0.7...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2017
Entry Details
US Patent

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