Compile Data Set for Download or QSAR
Report error Found 274 Enz. Inhib. hit(s) with all data for entry = 8472
TargetGlycogen synthase kinase-3 beta(Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 251572BDBM251572(US9452998, Table 4 Compound 2)
Affinity DataIC50: 0.100nMpH: 7.0 T: 2°CAssay Description:Types of GSK-3 assay used to test the selectivity/off target potential compounds of the invention with respect to PKC ±/ inhibition activity includes...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2017
Entry Details
US Patent

TargetProtein kinase C alpha type(Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 251491BDBM251491(US9452998, 51 | US9452998, 40)
Affinity DataIC50: 0.130nMpH: 7.4Assay Description:The compounds of formula I were tested for their activity on different PKC isoforms according to a published method (D. Geiges et al. Biochem. Pharma...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2017
Entry Details
US Patent

TargetProtein kinase C alpha type(Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 251496BDBM251496(US9452998, 45)
Affinity DataIC50: 0.130nMpH: 7.4Assay Description:The compounds of formula I were tested for their activity on different PKC isoforms according to a published method (D. Geiges et al. Biochem. Pharma...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2017
Entry Details
US Patent

TargetProtein kinase C alpha type(Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 251574BDBM251574(US9452998, Table 4 Compound 4)
Affinity DataIC50: 0.130nMpH: 7.4Assay Description:The compounds of formula I were tested for their activity on different PKC isoforms according to a published method (D. Geiges et al. Biochem. Pharma...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2017
Entry Details
US Patent

TargetProtein kinase C alpha type(Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 251497BDBM251497(US9452998, 46)
Affinity DataIC50: 0.130nMpH: 7.4Assay Description:The compounds of formula I were tested for their activity on different PKC isoforms according to a published method (D. Geiges et al. Biochem. Pharma...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2017
Entry Details
US Patent

TargetProtein kinase C alpha type(Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 251572BDBM251572(US9452998, Table 4 Compound 2)
Affinity DataIC50: 0.130nMpH: 7.4Assay Description:The compounds of formula I were tested for their activity on different PKC isoforms according to a published method (D. Geiges et al. Biochem. Pharma...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2017
Entry Details
US Patent

TargetProtein kinase C alpha type(Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 251506BDBM251506(US9452998, 55)
Affinity DataIC50: 0.130nMpH: 7.4Assay Description:The compounds of formula I were tested for their activity on different PKC isoforms according to a published method (D. Geiges et al. Biochem. Pharma...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2017
Entry Details
US Patent

TargetProtein kinase C alpha type(Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 251507BDBM251507(US9452998, 76 | US9452998, 56)
Affinity DataIC50: 0.130nMpH: 7.4Assay Description:The compounds of formula I were tested for their activity on different PKC isoforms according to a published method (D. Geiges et al. Biochem. Pharma...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2017
Entry Details
US Patent

TargetProtein kinase C theta type(Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 251525BDBM251525(US9452998, 74)
Affinity DataIC50: 0.130nMpH: 7.4Assay Description:The compounds of formula I were tested for their activity on different PKC isoforms according to a published method (D. Geiges et al. Biochem. Pharma...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2017
Entry Details
US Patent

TargetProtein kinase C alpha type(Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 251515BDBM251515(US9452998, 64)
Affinity DataIC50: 0.130nMpH: 7.4Assay Description:The compounds of formula I were tested for their activity on different PKC isoforms according to a published method (D. Geiges et al. Biochem. Pharma...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2017
Entry Details
US Patent

TargetProtein kinase C alpha type(Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 251512BDBM251512(US9452998, 61)
Affinity DataIC50: 0.130nMpH: 7.4Assay Description:The compounds of formula I were tested for their activity on different PKC isoforms according to a published method (D. Geiges et al. Biochem. Pharma...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2017
Entry Details
US Patent

TargetProtein kinase C alpha type(Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 251513BDBM251513(US9452998, 62)
Affinity DataIC50: 0.130nMpH: 7.4Assay Description:The compounds of formula I were tested for their activity on different PKC isoforms according to a published method (D. Geiges et al. Biochem. Pharma...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2017
Entry Details
US Patent

TargetProtein kinase C alpha type(Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 251508BDBM251508(US9452998, 57)
Affinity DataIC50: 0.130nMpH: 7.4Assay Description:The compounds of formula I were tested for their activity on different PKC isoforms according to a published method (D. Geiges et al. Biochem. Pharma...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2017
Entry Details
US Patent

TargetProtein kinase C alpha type(Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 251509BDBM251509(US9452998, 58)
Affinity DataIC50: 0.130nMpH: 7.4Assay Description:The compounds of formula I were tested for their activity on different PKC isoforms according to a published method (D. Geiges et al. Biochem. Pharma...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2017
Entry Details
US Patent

TargetProtein kinase C alpha type(Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 251458BDBM251458(US9452998, 7)
Affinity DataIC50: 0.130nMpH: 7.4Assay Description:The compounds of formula I were tested for their activity on different PKC isoforms according to a published method (D. Geiges et al. Biochem. Pharma...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2017
Entry Details
US Patent

TargetProtein kinase C alpha type(Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 251522BDBM251522(US9452998, 71)
Affinity DataIC50: 0.130nMpH: 7.4Assay Description:The compounds of formula I were tested for their activity on different PKC isoforms according to a published method (D. Geiges et al. Biochem. Pharma...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2017
Entry Details
US Patent

TargetProtein kinase C alpha type(Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 251523BDBM251523(US9452998, 78 | US9452998, 72)
Affinity DataIC50: 0.130nMpH: 7.4Assay Description:The compounds of formula I were tested for their activity on different PKC isoforms according to a published method (D. Geiges et al. Biochem. Pharma...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2017
Entry Details
US Patent

TargetProtein kinase C alpha type(Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 251455BDBM251455(US9452998, 4)
Affinity DataIC50: 0.130nMpH: 7.4Assay Description:The compounds of formula I were tested for their activity on different PKC isoforms according to a published method (D. Geiges et al. Biochem. Pharma...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2017
Entry Details
US Patent

TargetProtein kinase C alpha type(Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 251516BDBM251516(US9452998, 65)
Affinity DataIC50: 0.130nMpH: 7.4Assay Description:The compounds of formula I were tested for their activity on different PKC isoforms according to a published method (D. Geiges et al. Biochem. Pharma...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2017
Entry Details
US Patent

TargetProtein kinase C alpha type(Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 251517BDBM251517(US9452998, 77 | US9452998, 66)
Affinity DataIC50: 0.130nMpH: 7.4Assay Description:The compounds of formula I were tested for their activity on different PKC isoforms according to a published method (D. Geiges et al. Biochem. Pharma...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2017
Entry Details
US Patent

TargetProtein kinase C alpha type(Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 251517BDBM251517(US9452998, 77 | US9452998, 66)
Affinity DataIC50: 0.130nMpH: 7.4Assay Description:The compounds of formula I were tested for their activity on different PKC isoforms according to a published method (D. Geiges et al. Biochem. Pharma...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2017
Entry Details
US Patent

TargetProtein kinase C alpha type(Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 251523BDBM251523(US9452998, 78 | US9452998, 72)
Affinity DataIC50: 0.130nMpH: 7.4Assay Description:The compounds of formula I were tested for their activity on different PKC isoforms according to a published method (D. Geiges et al. Biochem. Pharma...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2017
Entry Details
US Patent

TargetProtein kinase C alpha type(Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 251507BDBM251507(US9452998, 76 | US9452998, 56)
Affinity DataIC50: 0.130nMpH: 7.4Assay Description:The compounds of formula I were tested for their activity on different PKC isoforms according to a published method (D. Geiges et al. Biochem. Pharma...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2017
Entry Details
US Patent

TargetProtein kinase C alpha type(Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 251524BDBM251524(US9452998, 73)
Affinity DataIC50: 0.130nMpH: 7.4Assay Description:The compounds of formula I were tested for their activity on different PKC isoforms according to a published method (D. Geiges et al. Biochem. Pharma...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2017
Entry Details
US Patent

TargetProtein kinase C theta type(Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 251544BDBM251544(US9452998, 93)
Affinity DataIC50: 0.130nMpH: 7.4Assay Description:The compounds of formula I were tested for their activity on different PKC isoforms according to a published method (D. Geiges et al. Biochem. Pharma...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2017
Entry Details
US Patent

TargetProtein kinase C alpha type(Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 251544BDBM251544(US9452998, 93)
Affinity DataIC50: 0.130nMpH: 7.4Assay Description:The compounds of formula I were tested for their activity on different PKC isoforms according to a published method (D. Geiges et al. Biochem. Pharma...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2017
Entry Details
US Patent

TargetProtein kinase C alpha type(Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 251511BDBM251511(US9452998, 60)
Affinity DataIC50: 0.140nMpH: 7.4Assay Description:The compounds of formula I were tested for their activity on different PKC isoforms according to a published method (D. Geiges et al. Biochem. Pharma...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2017
Entry Details
US Patent

TargetProtein kinase C alpha type(Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 251573BDBM251573(US9452998, Table 4 Compound 3)
Affinity DataIC50: 0.150nMpH: 7.4Assay Description:The compounds of formula I were tested for their activity on different PKC isoforms according to a published method (D. Geiges et al. Biochem. Pharma...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2017
Entry Details
US Patent

TargetProtein kinase C theta type(Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 251524BDBM251524(US9452998, 73)
Affinity DataIC50: 0.160nMpH: 7.4Assay Description:The compounds of formula I were tested for their activity on different PKC isoforms according to a published method (D. Geiges et al. Biochem. Pharma...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2017
Entry Details
US Patent

TargetProtein kinase C alpha type(Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 251540BDBM251540(US9452998, 89)
Affinity DataIC50: 0.160nMpH: 7.4Assay Description:The compounds of formula I were tested for their activity on different PKC isoforms according to a published method (D. Geiges et al. Biochem. Pharma...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2017
Entry Details
US Patent

TargetProtein kinase C alpha type(Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 251493BDBM251493(US9452998, 42)
Affinity DataIC50: 0.170nMpH: 7.4Assay Description:The compounds of formula I were tested for their activity on different PKC isoforms according to a published method (D. Geiges et al. Biochem. Pharma...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2017
Entry Details
US Patent

TargetProtein kinase C alpha type(Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 251501BDBM251501(US9452998, 50)
Affinity DataIC50: 0.190nMpH: 7.4Assay Description:The compounds of formula I were tested for their activity on different PKC isoforms according to a published method (D. Geiges et al. Biochem. Pharma...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2017
Entry Details
US Patent

TargetProtein kinase C alpha type(Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 251575BDBM251575(US9452998, Table 4 Compound 5)
Affinity DataIC50: 0.190nMpH: 7.4Assay Description:The compounds of formula I were tested for their activity on different PKC isoforms according to a published method (D. Geiges et al. Biochem. Pharma...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2017
Entry Details
US Patent

TargetProtein kinase C alpha type(Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 251504BDBM251504(US9452998, 53)
Affinity DataIC50: 0.200nMpH: 7.4Assay Description:The compounds of formula I were tested for their activity on different PKC isoforms according to a published method (D. Geiges et al. Biochem. Pharma...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2017
Entry Details
US Patent

TargetProtein kinase C theta type(Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 251523BDBM251523(US9452998, 78 | US9452998, 72)
Affinity DataIC50: 0.200nMpH: 7.4Assay Description:The compounds of formula I were tested for their activity on different PKC isoforms according to a published method (D. Geiges et al. Biochem. Pharma...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2017
Entry Details
US Patent

TargetProtein kinase C alpha type(Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 251491BDBM251491(US9452998, 51 | US9452998, 40)
Affinity DataIC50: 0.200nMpH: 7.4Assay Description:The compounds of formula I were tested for their activity on different PKC isoforms according to a published method (D. Geiges et al. Biochem. Pharma...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2017
Entry Details
US Patent

TargetProtein kinase C theta type(Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 251523BDBM251523(US9452998, 78 | US9452998, 72)
Affinity DataIC50: 0.200nMpH: 7.4Assay Description:The compounds of formula I were tested for their activity on different PKC isoforms according to a published method (D. Geiges et al. Biochem. Pharma...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2017
Entry Details
US Patent

TargetGlycogen synthase kinase-3 beta(Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 251575BDBM251575(US9452998, Table 4 Compound 5)
Affinity DataIC50: 0.200nMpH: 7.0 T: 2°CAssay Description:Types of GSK-3 assay used to test the selectivity/off target potential compounds of the invention with respect to PKC ±/ inhibition activity includes...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2017
Entry Details
US Patent

TargetGlycogen synthase kinase-3 beta(Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 251576BDBM251576(US9452998, Table 4 Compound 6)
Affinity DataIC50: 0.200nMpH: 7.0 T: 2°CAssay Description:Types of GSK-3 assay used to test the selectivity/off target potential compounds of the invention with respect to PKC ±/ inhibition activity includes...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2017
Entry Details
US Patent

TargetGlycogen synthase kinase-3 beta(Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 251574BDBM251574(US9452998, Table 4 Compound 4)
Affinity DataIC50: 0.200nMpH: 7.0 T: 2°CAssay Description:Types of GSK-3 assay used to test the selectivity/off target potential compounds of the invention with respect to PKC ±/ inhibition activity includes...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2017
Entry Details
US Patent

TargetProtein kinase C alpha type(Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 251457BDBM251457(US9452998, 6)
Affinity DataIC50: 0.220nMpH: 7.4Assay Description:The compounds of formula I were tested for their activity on different PKC isoforms according to a published method (D. Geiges et al. Biochem. Pharma...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2017
Entry Details
US Patent

TargetProtein kinase C theta type(Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 251522BDBM251522(US9452998, 71)
Affinity DataIC50: 0.230nMpH: 7.4Assay Description:The compounds of formula I were tested for their activity on different PKC isoforms according to a published method (D. Geiges et al. Biochem. Pharma...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2017
Entry Details
US Patent

TargetProtein kinase C alpha type(Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 251480BDBM251480(US9452998, 29)
Affinity DataIC50: 0.240nMpH: 7.4Assay Description:The compounds of formula I were tested for their activity on different PKC isoforms according to a published method (D. Geiges et al. Biochem. Pharma...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2017
Entry Details
US Patent

TargetProtein kinase C theta type(Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 251521BDBM251521(US9452998, 70)
Affinity DataIC50: 0.240nMpH: 7.4Assay Description:The compounds of formula I were tested for their activity on different PKC isoforms according to a published method (D. Geiges et al. Biochem. Pharma...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2017
Entry Details
US Patent

TargetProtein kinase C alpha type(Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 251505BDBM251505(US9452998, 54)
Affinity DataIC50: 0.25nMpH: 7.4Assay Description:The compounds of formula I were tested for their activity on different PKC isoforms according to a published method (D. Geiges et al. Biochem. Pharma...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2017
Entry Details
US Patent

TargetProtein kinase C theta type(Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 251573BDBM251573(US9452998, Table 4 Compound 3)
Affinity DataIC50: 0.25nMpH: 7.4Assay Description:The compounds of formula I were tested for their activity on different PKC isoforms according to a published method (D. Geiges et al. Biochem. Pharma...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2017
Entry Details
US Patent

TargetProtein kinase C alpha type(Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 251453BDBM251453(US9452998, 2)
Affinity DataIC50: 0.25nMpH: 7.4Assay Description:The compounds of formula I were tested for their activity on different PKC isoforms according to a published method (D. Geiges et al. Biochem. Pharma...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2017
Entry Details
US Patent

TargetProtein kinase C alpha type(Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 251543BDBM251543(US9452998, 92)
Affinity DataIC50: 0.25nMpH: 7.4Assay Description:The compounds of formula I were tested for their activity on different PKC isoforms according to a published method (D. Geiges et al. Biochem. Pharma...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2017
Entry Details
US Patent

TargetProtein kinase C alpha type(Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 251566BDBM251566(US9452998, 115)
Affinity DataIC50: 0.260nMpH: 7.4Assay Description:The compounds of formula I were tested for their activity on different PKC isoforms according to a published method (D. Geiges et al. Biochem. Pharma...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2017
Entry Details
US Patent

TargetProtein kinase C alpha type(Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 251498BDBM251498(US9452998, 47)
Affinity DataIC50: 0.270nMpH: 7.4Assay Description:The compounds of formula I were tested for their activity on different PKC isoforms according to a published method (D. Geiges et al. Biochem. Pharma...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2017
Entry Details
US Patent

Displayed 1 to 50 (of 274 total ) | Next | Last >>
Jump to: