Compile Data Set for Download or QSAR
Report error Found 210 Enz. Inhib. hit(s) with all data for entry = 8506
LigandChemical structure of BindingDB Monomer ID 254598BDBM254598(US9670136, 57 N1-((trans)-2-(4-((2-fluorobenzyl)ox...)
Affinity DataIC50: 12nMpH: 7.4 T: 2°CAssay Description:The compounds of the invention can be tested for their ability to inhibit LSD1. The ability of the compounds of the invention to inhibit LSD1 can be ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2017
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 50155773BDBM50155773(US9469597, 5 | CHEMBL3781751)
Affinity DataIC50: 15nMpH: 7.4 T: 2°CAssay Description:The compounds of the invention can be tested for their ability to inhibit LSD1. The ability of the compounds of the invention to inhibit LSD1 can be ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2017
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 254546BDBM254546(US9670136, 5 (trans)-N1-((1R,2S)-2-phenylcycloprop...)
Affinity DataIC50: 17nMpH: 7.4 T: 2°CAssay Description:The compounds of the invention can be tested for their ability to inhibit LSD1. The ability of the compounds of the invention to inhibit LSD1 can be ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2017
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 254593BDBM254593(US9469597, 52)
Affinity DataIC50: 19nMpH: 7.4 T: 2°CAssay Description:The compounds of the invention can be tested for their ability to inhibit LSD1. The ability of the compounds of the invention to inhibit LSD1 can be ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2017
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 254574BDBM254574(US9670136, 33 N1-(2-(naphthalen-2-yl)cyclopropyl)c...)
Affinity DataIC50: 21nMpH: 7.4 T: 2°CAssay Description:The compounds of the invention can be tested for their ability to inhibit LSD1. The ability of the compounds of the invention to inhibit LSD1 can be ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2017
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 254584BDBM254584(US9670136, 43 N1-((trans)-2-(4-(1H-pyrazol-5-yl)ph...)
Affinity DataIC50: 22nMpH: 7.4 T: 2°CAssay Description:The compounds of the invention can be tested for their ability to inhibit LSD1. The ability of the compounds of the invention to inhibit LSD1 can be ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2017
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 254589BDBM254589(US9670136, 48 N-(4′-((trans)-2-((4-aminocycl...)
Affinity DataIC50: 27nMpH: 7.4 T: 2°CAssay Description:The compounds of the invention can be tested for their ability to inhibit LSD1. The ability of the compounds of the invention to inhibit LSD1 can be ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2017
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 254568BDBM254568(US9670136, 27 N1-(2-(o-tolyl)cyclopropyl)cyclohexa...)
Affinity DataIC50: 27nMpH: 7.4 T: 2°CAssay Description:The compounds of the invention can be tested for their ability to inhibit LSD1. The ability of the compounds of the invention to inhibit LSD1 can be ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2017
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 254583BDBM254583(US9670136, 42 N1-((trans)-2-(4-(1H-indazol-6-yl)ph...)
Affinity DataIC50: 27nMpH: 7.4 T: 2°CAssay Description:The compounds of the invention can be tested for their ability to inhibit LSD1. The ability of the compounds of the invention to inhibit LSD1 can be ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2017
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 254592BDBM254592(US9469597, 51)
Affinity DataIC50: 30nMpH: 7.4 T: 2°CAssay Description:The compounds of the invention can be tested for their ability to inhibit LSD1. The ability of the compounds of the invention to inhibit LSD1 can be ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2017
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 254586BDBM254586(US9670136, 45 3-(5-((trans)-2-((4-aminocyclohexyl)...)
Affinity DataIC50: 32nMpH: 7.4 T: 2°CAssay Description:The compounds of the invention can be tested for their ability to inhibit LSD1. The ability of the compounds of the invention to inhibit LSD1 can be ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2017
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 254596BDBM254596(US9670136, 55 N1-((trans)-2-(4-((3-(piperazin-1-yl...)
Affinity DataIC50: 33nMpH: 7.4 T: 2°CAssay Description:The compounds of the invention can be tested for their ability to inhibit LSD1. The ability of the compounds of the invention to inhibit LSD1 can be ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2017
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 254603BDBM254603(US9670136, 3 (trans)-N1-((1S,2R)-2-phenylcycloprop...)
Affinity DataIC50: 33nMpH: 7.4 T: 2°CAssay Description:The compounds of the invention can be tested for their ability to inhibit LSD1. The ability of the compounds of the invention to inhibit LSD1 can be ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2017
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 254581BDBM254581(US9670136, 40 N1-((trans)-2-(4-cyclopropylphenyl)c...)
Affinity DataIC50: 34nMpH: 7.4 T: 2°CAssay Description:The compounds of the invention can be tested for their ability to inhibit LSD1. The ability of the compounds of the invention to inhibit LSD1 can be ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2017
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 254547BDBM254547(US9670136, 6 N1-((trans)-2-(thiazol-5-yl)cycloprop...)
Affinity DataIC50: 34nMpH: 7.4 T: 2°CAssay Description:The compounds of the invention can be tested for their ability to inhibit LSD1. The ability of the compounds of the invention to inhibit LSD1 can be ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2017
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 254561BDBM254561(US9670136, 20 N1-((trans)-2-phenylcyclopropyl)-2,3...)
Affinity DataIC50: 34nMpH: 7.4 T: 2°CAssay Description:The compounds of the invention can be tested for their ability to inhibit LSD1. The ability of the compounds of the invention to inhibit LSD1 can be ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2017
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 254572BDBM254572(US9670136, 31 N1-(2-(2-fluorophenyl)cyclopropyl)cy...)
Affinity DataIC50: 35nMpH: 7.4 T: 2°CAssay Description:The compounds of the invention can be tested for their ability to inhibit LSD1. The ability of the compounds of the invention to inhibit LSD1 can be ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2017
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 254570BDBM254570(US9670136, 29 N1-(2-(4-methoxyphenyl)cyclopropyl)c...)
Affinity DataIC50: 36nMpH: 7.4 T: 2°CAssay Description:The compounds of the invention can be tested for their ability to inhibit LSD1. The ability of the compounds of the invention to inhibit LSD1 can be ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2017
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 254573BDBM254573(US9670136, 32 N1-(2-(3,4-difluorophenyl)cyclopropy...)
Affinity DataIC50: 37nMpH: 7.4 T: 2°CAssay Description:The compounds of the invention can be tested for their ability to inhibit LSD1. The ability of the compounds of the invention to inhibit LSD1 can be ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2017
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 254569BDBM254569(US9670136, 28 N1-(2-(4-(trifluoromethyl)phenyl)cyc...)
Affinity DataIC50: 37nMpH: 7.4 T: 2°CAssay Description:The compounds of the invention can be tested for their ability to inhibit LSD1. The ability of the compounds of the invention to inhibit LSD1 can be ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2017
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 254551BDBM254551(US9670136, 10 N1-((trans)-2-(4-(benzyloxy)phenyl)c...)
Affinity DataIC50: 40nMpH: 7.4 T: 2°CAssay Description:The compounds of the invention can be tested for their ability to inhibit LSD1. The ability of the compounds of the invention to inhibit LSD1 can be ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2017
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 254585BDBM254585(US9670136, 44 3-(5-((trans)-2-((4-aminocyclohexyl)...)
Affinity DataIC50: 41nMpH: 7.4 T: 2°CAssay Description:The compounds of the invention can be tested for their ability to inhibit LSD1. The ability of the compounds of the invention to inhibit LSD1 can be ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2017
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 254599BDBM254599(US9670136, 58 N1-((trans)-2-(6-((3-methylbenzyl)am...)
Affinity DataIC50: 42nMpH: 7.4 T: 2°CAssay Description:The compounds of the invention can be tested for their ability to inhibit LSD1. The ability of the compounds of the invention to inhibit LSD1 can be ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2017
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 254594BDBM254594(US9670136, 53 N1-((trans)-2-fluoro-2-phenylcyclopr...)
Affinity DataIC50: 45nMpH: 7.4 T: 2°CAssay Description:The compounds of the invention can be tested for their ability to inhibit LSD1. The ability of the compounds of the invention to inhibit LSD1 can be ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2017
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 254559BDBM254559(US9670136, 18 N1-((trans)-2-phenylcyclopropyl)cycl...)
Affinity DataIC50: 45nMpH: 7.4 T: 2°CAssay Description:The compounds of the invention can be tested for their ability to inhibit LSD1. The ability of the compounds of the invention to inhibit LSD1 can be ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2017
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 254575BDBM254575(US9670136, 34 N1-(2-methyl-2-phenylcyclopropyl)cyc...)
Affinity DataIC50: 47nMpH: 7.4 T: 2°CAssay Description:The compounds of the invention can be tested for their ability to inhibit LSD1. The ability of the compounds of the invention to inhibit LSD1 can be ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2017
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 254582BDBM254582(US9670136, 41 N1-((trans)-2-(4-(pyridin-3-yl)pheny...)
Affinity DataIC50: 47nMpH: 7.4 T: 2°CAssay Description:The compounds of the invention can be tested for their ability to inhibit LSD1. The ability of the compounds of the invention to inhibit LSD1 can be ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2017
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 254550BDBM254550(US9670136, 9 N1-((trans)-2-(3′-(trifluoromet...)
Affinity DataIC50: 48nMpH: 7.4 T: 2°CAssay Description:The compounds of the invention can be tested for their ability to inhibit LSD1. The ability of the compounds of the invention to inhibit LSD1 can be ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2017
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 254603BDBM254603(US9670136, 3 (trans)-N1-((1S,2R)-2-phenylcycloprop...)
Affinity DataKi:  50nM ΔG°:  -43.3kJ/molepH: 7.4 T: 2°CAssay Description:The compounds of the invention can be tested for their ability to inhibit LSD1. The ability of the compounds of the invention to inhibit LSD1 can be ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2017
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 50155773BDBM50155773(US9469597, 5 | CHEMBL3781751)
Affinity DataKi:  50nM ΔG°:  -43.3kJ/molepH: 7.4 T: 2°CAssay Description:The compounds of the invention can be tested for their ability to inhibit LSD1. The ability of the compounds of the invention to inhibit LSD1 can be ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2017
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 254546BDBM254546(US9670136, 5 (trans)-N1-((1R,2S)-2-phenylcycloprop...)
Affinity DataKi:  50nM ΔG°:  -43.3kJ/molepH: 7.4 T: 2°CAssay Description:The compounds of the invention can be tested for their ability to inhibit LSD1. The ability of the compounds of the invention to inhibit LSD1 can be ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2017
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 254556BDBM254556(US9670136, 15 (R)-1-(4-(((trans)-2-phenylcycloprop...)
Affinity DataKi:  50nM ΔG°:  -43.3kJ/molepH: 7.4 T: 2°CAssay Description:The compounds of the invention can be tested for their ability to inhibit LSD1. The ability of the compounds of the invention to inhibit LSD1 can be ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2017
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 254553BDBM254553(US9670136, 12 4-(((trans)-2-(6-(3-(trifluoromethyl...)
Affinity DataKi:  50nM ΔG°:  -43.3kJ/molepH: 7.4 T: 2°CAssay Description:The compounds of the invention can be tested for their ability to inhibit LSD1. The ability of the compounds of the invention to inhibit LSD1 can be ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2017
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 254567BDBM254567(US9670136, 26 N1-((trans)-2-(4-bromophenyl)cyclopr...)
Affinity DataIC50: 51nMpH: 7.4 T: 2°CAssay Description:The compounds of the invention can be tested for their ability to inhibit LSD1. The ability of the compounds of the invention to inhibit LSD1 can be ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2017
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 254562BDBM254562(US9670136, 21 N1-((cis)-2-phenylcyclopropyl)cycloh...)
Affinity DataIC50: 53nMpH: 7.4 T: 2°CAssay Description:The compounds of the invention can be tested for their ability to inhibit LSD1. The ability of the compounds of the invention to inhibit LSD1 can be ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2017
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 254579BDBM254579(US9670136, 38 (Cis)-N1-((1R,2S)-2-(3′-(trifl...)
Affinity DataIC50: 53nMpH: 7.4 T: 2°CAssay Description:The compounds of the invention can be tested for their ability to inhibit LSD1. The ability of the compounds of the invention to inhibit LSD1 can be ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2017
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 254600BDBM254600(US9670136, 59 3-((5-((trans)-2-((4-aminocyclohexyl...)
Affinity DataIC50: 54nMpH: 7.4 T: 2°CAssay Description:The compounds of the invention can be tested for their ability to inhibit LSD1. The ability of the compounds of the invention to inhibit LSD1 can be ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2017
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 254558BDBM254558(US9670136, 17 4-(aminomethyl)-N-((trans)-phenylcyc...)
Affinity DataIC50: 62nMpH: 7.4 T: 2°CAssay Description:The compounds of the invention can be tested for their ability to inhibit LSD1. The ability of the compounds of the invention to inhibit LSD1 can be ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2017
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 254591BDBM254591(US9469597, 50)
Affinity DataIC50: 62nMpH: 7.4 T: 2°CAssay Description:The compounds of the invention can be tested for their ability to inhibit LSD1. The ability of the compounds of the invention to inhibit LSD1 can be ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2017
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 254563BDBM254563(US9670136, 22 N1-methyl-N4-((trans)-2-phenylcyclop...)
Affinity DataIC50: 66nMpH: 7.4 T: 2°CAssay Description:The compounds of the invention can be tested for their ability to inhibit LSD1. The ability of the compounds of the invention to inhibit LSD1 can be ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2017
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 254560BDBM254560(US9670136, 19 N1-((trans)-2-phenylcyclopropyl)cycl...)
Affinity DataIC50: 68nMpH: 7.4 T: 2°CAssay Description:The compounds of the invention can be tested for their ability to inhibit LSD1. The ability of the compounds of the invention to inhibit LSD1 can be ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2017
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 254548BDBM254548(US9670136, 7 N1-((trans)-2-(pyridin-3-yl)cycloprop...)
Affinity DataIC50: 69nMpH: 7.4 T: 2°CAssay Description:The compounds of the invention can be tested for their ability to inhibit LSD1. The ability of the compounds of the invention to inhibit LSD1 can be ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2017
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 254590BDBM254590(US9670136, 49 N-(3-(5-((trans)-2-((4-aminocyclohex...)
Affinity DataIC50: 79nMpH: 7.4 T: 2°CAssay Description:The compounds of the invention can be tested for their ability to inhibit LSD1. The ability of the compounds of the invention to inhibit LSD1 can be ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2017
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 254556BDBM254556(US9670136, 15 (R)-1-(4-(((trans)-2-phenylcycloprop...)
Affinity DataIC50: 81nMpH: 7.4 T: 2°CAssay Description:The compounds of the invention can be tested for their ability to inhibit LSD1. The ability of the compounds of the invention to inhibit LSD1 can be ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2017
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 254588BDBM254588(US9670136, 47 5-(5-((trans)-2-((4-aminocyclohexyl)...)
Affinity DataIC50: 83nMpH: 7.4 T: 2°CAssay Description:The compounds of the invention can be tested for their ability to inhibit LSD1. The ability of the compounds of the invention to inhibit LSD1 can be ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2017
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 254577BDBM254577(US9670136, 36 (Cis)-N1-((1S,2R)-2-(3′-(trifl...)
Affinity DataIC50: 86nMpH: 7.4 T: 2°CAssay Description:The compounds of the invention can be tested for their ability to inhibit LSD1. The ability of the compounds of the invention to inhibit LSD1 can be ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2017
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 254580BDBM254580(US9670136, 39 (Trans)-N1-((1R,2S)-2-(3′-(tri...)
Affinity DataIC50: 89nMpH: 7.4 T: 2°CAssay Description:The compounds of the invention can be tested for their ability to inhibit LSD1. The ability of the compounds of the invention to inhibit LSD1 can be ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2017
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 254553BDBM254553(US9670136, 12 4-(((trans)-2-(6-(3-(trifluoromethyl...)
Affinity DataIC50: 91nMpH: 7.4 T: 2°CAssay Description:The compounds of the invention can be tested for their ability to inhibit LSD1. The ability of the compounds of the invention to inhibit LSD1 can be ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2017
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 254597BDBM254597(US9670136, 56 N1-((trans)-2-(4-(pyridin-3-ylmethox...)
Affinity DataIC50: 94nMpH: 7.4 T: 2°CAssay Description:The compounds of the invention can be tested for their ability to inhibit LSD1. The ability of the compounds of the invention to inhibit LSD1 can be ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2017
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 254578BDBM254578(US9670136, 37 (Trans)-N1-((1S,2R)-2-(3′-(tri...)
Affinity DataIC50: 94nMpH: 7.4 T: 2°CAssay Description:The compounds of the invention can be tested for their ability to inhibit LSD1. The ability of the compounds of the invention to inhibit LSD1 can be ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2017
Entry Details
US Patent

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