Compile Data Set for Download or QSAR
Report error Found 44 Enz. Inhib. hit(s) with all data for entry = 8487
TargetProthrombin(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 252994BDBM252994(US9469608, 23-4b)
Affinity DataKi:  1.10nMpH: 7.4Assay Description:Relevant in vitro assays are referenced in Morrissette, et al., Bioorg. Med. Chem. Lett. 2004, 14, 4161-4164 and described in Lewis, et al. Thromb. R...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2017
Entry Details
US Patent

TargetProthrombin(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 253006BDBM253006(US9469608, 34-7)
Affinity DataKi:  2.5nMpH: 7.4Assay Description:Relevant in vitro assays are referenced in Morrissette, et al., Bioorg. Med. Chem. Lett. 2004, 14, 4161-4164 and described in Lewis, et al. Thromb. R...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2017
Entry Details
US Patent

TargetProthrombin(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 253008BDBM253008(US9469608, 36-3)
Affinity DataKi:  2.5nMpH: 7.4Assay Description:Relevant in vitro assays are referenced in Morrissette, et al., Bioorg. Med. Chem. Lett. 2004, 14, 4161-4164 and described in Lewis, et al. Thromb. R...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2017
Entry Details
US Patent

TargetProthrombin(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 252985BDBM252985(US9469608, 13-10)
Affinity DataKi:  3.40nMpH: 7.4Assay Description:Relevant in vitro assays are referenced in Morrissette, et al., Bioorg. Med. Chem. Lett. 2004, 14, 4161-4164 and described in Lewis, et al. Thromb. R...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2017
Entry Details
US Patent

TargetProthrombin(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 253013BDBM253013(US9469608, 39-10b)
Affinity DataKi:  3.40nMpH: 7.4Assay Description:Relevant in vitro assays are referenced in Morrissette, et al., Bioorg. Med. Chem. Lett. 2004, 14, 4161-4164 and described in Lewis, et al. Thromb. R...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2017
Entry Details
US Patent

TargetProthrombin(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 253012BDBM253012(US9469608, 39-10a)
Affinity DataKi:  3.40nMpH: 7.4Assay Description:Relevant in vitro assays are referenced in Morrissette, et al., Bioorg. Med. Chem. Lett. 2004, 14, 4161-4164 and described in Lewis, et al. Thromb. R...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2017
Entry Details
US Patent

TargetProthrombin(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 253004BDBM253004(US9469608, 32-7)
Affinity DataKi:  3.90nMpH: 7.4Assay Description:Relevant in vitro assays are referenced in Morrissette, et al., Bioorg. Med. Chem. Lett. 2004, 14, 4161-4164 and described in Lewis, et al. Thromb. R...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2017
Entry Details
US Patent

TargetProthrombin(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 253003BDBM253003(US9469608, 31-7)
Affinity DataKi:  4.80nMpH: 7.4Assay Description:Relevant in vitro assays are referenced in Morrissette, et al., Bioorg. Med. Chem. Lett. 2004, 14, 4161-4164 and described in Lewis, et al. Thromb. R...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2017
Entry Details
US Patent

TargetProthrombin(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 252990BDBM252990(US9469608, 20-8)
Affinity DataKi:  7.70nMpH: 7.4Assay Description:Relevant in vitro assays are referenced in Morrissette, et al., Bioorg. Med. Chem. Lett. 2004, 14, 4161-4164 and described in Lewis, et al. Thromb. R...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2017
Entry Details
US Patent

TargetProthrombin(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 252995BDBM252995(US9469608, 24-8)
Affinity DataKi:  9.20nMpH: 7.4Assay Description:Relevant in vitro assays are referenced in Morrissette, et al., Bioorg. Med. Chem. Lett. 2004, 14, 4161-4164 and described in Lewis, et al. Thromb. R...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2017
Entry Details
US Patent

TargetProthrombin(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 252984BDBM252984(US9469608, 11-2)
Affinity DataKi:  9.70nMpH: 7.4Assay Description:Relevant in vitro assays are referenced in Morrissette, et al., Bioorg. Med. Chem. Lett. 2004, 14, 4161-4164 and described in Lewis, et al. Thromb. R...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2017
Entry Details
US Patent

TargetProthrombin(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 253002BDBM253002(US9469608, 30-6)
Affinity DataKi:  11nMpH: 7.4Assay Description:Relevant in vitro assays are referenced in Morrissette, et al., Bioorg. Med. Chem. Lett. 2004, 14, 4161-4164 and described in Lewis, et al. Thromb. R...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2017
Entry Details
US Patent

TargetProthrombin(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 252982BDBM252982(US9469608, 9-2)
Affinity DataKi:  13nMpH: 7.4Assay Description:Relevant in vitro assays are referenced in Morrissette, et al., Bioorg. Med. Chem. Lett. 2004, 14, 4161-4164 and described in Lewis, et al. Thromb. R...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2017
Entry Details
US Patent

TargetProthrombin(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 252991BDBM252991(US9469608, 21-6)
Affinity DataKi:  15nMpH: 7.4Assay Description:Relevant in vitro assays are referenced in Morrissette, et al., Bioorg. Med. Chem. Lett. 2004, 14, 4161-4164 and described in Lewis, et al. Thromb. R...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2017
Entry Details
US Patent

TargetProthrombin(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 252999BDBM252999(US9469608, 28-6)
Affinity DataKi:  16nMpH: 7.4Assay Description:Relevant in vitro assays are referenced in Morrissette, et al., Bioorg. Med. Chem. Lett. 2004, 14, 4161-4164 and described in Lewis, et al. Thromb. R...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2017
Entry Details
US Patent

TargetProthrombin(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 252983BDBM252983(US9469608, 10-7)
Affinity DataKi:  17nMpH: 7.4Assay Description:Relevant in vitro assays are referenced in Morrissette, et al., Bioorg. Med. Chem. Lett. 2004, 14, 4161-4164 and described in Lewis, et al. Thromb. R...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2017
Entry Details
US Patent

TargetProthrombin(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 252980BDBM252980(US9469608, 7-1)
Affinity DataKi:  17nMpH: 7.4Assay Description:Relevant in vitro assays are referenced in Morrissette, et al., Bioorg. Med. Chem. Lett. 2004, 14, 4161-4164 and described in Lewis, et al. Thromb. R...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2017
Entry Details
US Patent

TargetProthrombin(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 252981BDBM252981(US9469608, 8-8)
Affinity DataKi:  18nMpH: 7.4Assay Description:Relevant in vitro assays are referenced in Morrissette, et al., Bioorg. Med. Chem. Lett. 2004, 14, 4161-4164 and described in Lewis, et al. Thromb. R...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2017
Entry Details
US Patent

TargetProthrombin(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 252998BDBM252998(US9469608, 27-9)
Affinity DataKi:  20nMpH: 7.4Assay Description:Relevant in vitro assays are referenced in Morrissette, et al., Bioorg. Med. Chem. Lett. 2004, 14, 4161-4164 and described in Lewis, et al. Thromb. R...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2017
Entry Details
US Patent

TargetProthrombin(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 252978BDBM252978(US9469608, 5-9 | US9469608, 6-2)
Affinity DataKi:  21nMpH: 7.4Assay Description:Relevant in vitro assays are referenced in Morrissette, et al., Bioorg. Med. Chem. Lett. 2004, 14, 4161-4164 and described in Lewis, et al. Thromb. R...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2017
Entry Details
US Patent

TargetProthrombin(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 252987BDBM252987(US9469608, 15-8)
Affinity DataKi:  22nMpH: 7.4Assay Description:Relevant in vitro assays are referenced in Morrissette, et al., Bioorg. Med. Chem. Lett. 2004, 14, 4161-4164 and described in Lewis, et al. Thromb. R...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2017
Entry Details
US Patent

TargetProthrombin(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 252986BDBM252986(US9469608, 14-5)
Affinity DataKi:  22nMpH: 7.4Assay Description:Relevant in vitro assays are referenced in Morrissette, et al., Bioorg. Med. Chem. Lett. 2004, 14, 4161-4164 and described in Lewis, et al. Thromb. R...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2017
Entry Details
US Patent

TargetProthrombin(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 252974BDBM252974(US9469608, 1-12)
Affinity DataKi:  25nMpH: 7.4Assay Description:Relevant in vitro assays are referenced in Morrissette, et al., Bioorg. Med. Chem. Lett. 2004, 14, 4161-4164 and described in Lewis, et al. Thromb. R...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2017
Entry Details
US Patent

TargetProthrombin(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 252977BDBM252977(US9469608, 4-5)
Affinity DataKi:  27nMpH: 7.4Assay Description:Relevant in vitro assays are referenced in Morrissette, et al., Bioorg. Med. Chem. Lett. 2004, 14, 4161-4164 and described in Lewis, et al. Thromb. R...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2017
Entry Details
US Patent

TargetProthrombin(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 253000BDBM253000(US9469608, 29-9a)
Affinity DataKi:  30nMpH: 7.4Assay Description:Relevant in vitro assays are referenced in Morrissette, et al., Bioorg. Med. Chem. Lett. 2004, 14, 4161-4164 and described in Lewis, et al. Thromb. R...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2017
Entry Details
US Patent

TargetProthrombin(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 253005BDBM253005(US9469608, 33-7)
Affinity DataKi:  39nMpH: 7.4Assay Description:Relevant in vitro assays are referenced in Morrissette, et al., Bioorg. Med. Chem. Lett. 2004, 14, 4161-4164 and described in Lewis, et al. Thromb. R...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2017
Entry Details
US Patent

TargetProthrombin(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 252976BDBM252976(US9469608, 3-5)
Affinity DataKi:  47nMpH: 7.4Assay Description:Relevant in vitro assays are referenced in Morrissette, et al., Bioorg. Med. Chem. Lett. 2004, 14, 4161-4164 and described in Lewis, et al. Thromb. R...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2017
Entry Details
US Patent

TargetProthrombin(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 252989BDBM252989(US9469608, 19-4)
Affinity DataKi:  49nMpH: 7.4Assay Description:Relevant in vitro assays are referenced in Morrissette, et al., Bioorg. Med. Chem. Lett. 2004, 14, 4161-4164 and described in Lewis, et al. Thromb. R...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2017
Entry Details
US Patent

TargetProthrombin(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 252996BDBM252996(US9469608, 25-5)
Affinity DataKi:  59nMpH: 7.4Assay Description:Relevant in vitro assays are referenced in Morrissette, et al., Bioorg. Med. Chem. Lett. 2004, 14, 4161-4164 and described in Lewis, et al. Thromb. R...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2017
Entry Details
US Patent

TargetProthrombin(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 253010BDBM253010(US9469608, 37-11b)
Affinity DataKi:  65nMpH: 7.4Assay Description:Relevant in vitro assays are referenced in Morrissette, et al., Bioorg. Med. Chem. Lett. 2004, 14, 4161-4164 and described in Lewis, et al. Thromb. R...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2017
Entry Details
US Patent

TargetProthrombin(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 252993BDBM252993(US9469608, 23-4a)
Affinity DataKi:  77nMpH: 7.4Assay Description:Relevant in vitro assays are referenced in Morrissette, et al., Bioorg. Med. Chem. Lett. 2004, 14, 4161-4164 and described in Lewis, et al. Thromb. R...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2017
Entry Details
US Patent

TargetProthrombin(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 252978BDBM252978(US9469608, 5-9 | US9469608, 6-2)
Affinity DataKi:  87nMpH: 7.4Assay Description:Relevant in vitro assays are referenced in Morrissette, et al., Bioorg. Med. Chem. Lett. 2004, 14, 4161-4164 and described in Lewis, et al. Thromb. R...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2017
Entry Details
US Patent

TargetProthrombin(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 253017BDBM253017(US9469608, 45)
Affinity DataKi:  93nMpH: 7.4Assay Description:Relevant in vitro assays are referenced in Morrissette, et al., Bioorg. Med. Chem. Lett. 2004, 14, 4161-4164 and described in Lewis, et al. Thromb. R...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2017
Entry Details
US Patent

TargetProthrombin(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 253001BDBM253001(US9469608, 29-9b)
Affinity DataKi:  100nMpH: 7.4Assay Description:Relevant in vitro assays are referenced in Morrissette, et al., Bioorg. Med. Chem. Lett. 2004, 14, 4161-4164 and described in Lewis, et al. Thromb. R...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2017
Entry Details
US Patent

TargetProthrombin(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 253011BDBM253011(US9469608, 38-4)
Affinity DataKi:  100nMpH: 7.4Assay Description:Relevant in vitro assays are referenced in Morrissette, et al., Bioorg. Med. Chem. Lett. 2004, 14, 4161-4164 and described in Lewis, et al. Thromb. R...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2017
Entry Details
US Patent

TargetProthrombin(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 253016BDBM253016(US9469608, 44)
Affinity DataKi:  104nMpH: 7.4Assay Description:Relevant in vitro assays are referenced in Morrissette, et al., Bioorg. Med. Chem. Lett. 2004, 14, 4161-4164 and described in Lewis, et al. Thromb. R...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2017
Entry Details
US Patent

TargetProthrombin(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 253007BDBM253007(US9469608, 35-7)
Affinity DataKi:  110nMpH: 7.4Assay Description:Relevant in vitro assays are referenced in Morrissette, et al., Bioorg. Med. Chem. Lett. 2004, 14, 4161-4164 and described in Lewis, et al. Thromb. R...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2017
Entry Details
US Patent

TargetProthrombin(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 252975BDBM252975(US9469608, 2-11)
Affinity DataKi:  110nMpH: 7.4Assay Description:Relevant in vitro assays are referenced in Morrissette, et al., Bioorg. Med. Chem. Lett. 2004, 14, 4161-4164 and described in Lewis, et al. Thromb. R...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2017
Entry Details
US Patent

TargetProthrombin(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 253014BDBM253014(US9469608, 42-3)
Affinity DataKi:  260nMpH: 7.4Assay Description:Relevant in vitro assays are referenced in Morrissette, et al., Bioorg. Med. Chem. Lett. 2004, 14, 4161-4164 and described in Lewis, et al. Thromb. R...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2017
Entry Details
US Patent

TargetProthrombin(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 252997BDBM252997(US9469608, 26-12)
Affinity DataKi:  325nMpH: 7.4Assay Description:Relevant in vitro assays are referenced in Morrissette, et al., Bioorg. Med. Chem. Lett. 2004, 14, 4161-4164 and described in Lewis, et al. Thromb. R...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2017
Entry Details
US Patent

TargetProthrombin(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 252992BDBM252992(US9469608, 22-10)
Affinity DataKi:  400nMpH: 7.4Assay Description:Relevant in vitro assays are referenced in Morrissette, et al., Bioorg. Med. Chem. Lett. 2004, 14, 4161-4164 and described in Lewis, et al. Thromb. R...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2017
Entry Details
US Patent

TargetProthrombin(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 253015BDBM253015(US9469608, 43)
Affinity DataKi:  526nMpH: 7.4Assay Description:Relevant in vitro assays are referenced in Morrissette, et al., Bioorg. Med. Chem. Lett. 2004, 14, 4161-4164 and described in Lewis, et al. Thromb. R...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2017
Entry Details
US Patent

TargetProthrombin(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 253009BDBM253009(US9469608, 37-11a)
Affinity DataKi:  720nMpH: 7.4Assay Description:Relevant in vitro assays are referenced in Morrissette, et al., Bioorg. Med. Chem. Lett. 2004, 14, 4161-4164 and described in Lewis, et al. Thromb. R...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2017
Entry Details
US Patent

TargetProthrombin(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 252988BDBM252988(US9469608, 17-5)
Affinity DataKi:  3.50E+3nMpH: 7.4Assay Description:Relevant in vitro assays are referenced in Morrissette, et al., Bioorg. Med. Chem. Lett. 2004, 14, 4161-4164 and described in Lewis, et al. Thromb. R...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2017
Entry Details
US Patent